Seroprevalence of measles and rubella in children and adolescents aged 7 to 19 years in Córdoba, Argentina, within the framework of the control and elimination program
The immunoprevention measures (vaccination by schedule plus mass campaigns) to achieve the objectives subscribed by PAHO/WHO produced around the year 2000 a sharp drop in cases of rubella and measles in Argentina. For this reason, there is currently a young population that only has immunity through...
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| Autores principales: | , , , , , , , |
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| Formato: | Artículo revista |
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Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
2022
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| Acceso en línea: | https://revistas.unc.edu.ar/index.php/med/article/view/38992 |
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| Sumario: | The immunoprevention measures (vaccination by schedule plus mass campaigns) to achieve the objectives subscribed by PAHO/WHO produced around the year 2000 a sharp drop in cases of rubella and measles in Argentina. For this reason, there is currently a young population that only has immunity through the vaccine. Objective: Given the latent risk of reintroduction of these viruses in the country, we set out to investigate the presence of anti-rubella and anti-measles IgG antibodies in people aged 7 to 19 years who, according to the National Immunization Calendar and data from the National Surveillance Program, they should have two doses of triple viral vaccine and should not have had contact with the virus naturally.
A retrospective, descriptive cross-sectional study was conducted. 180 samples from people between 7 and 19 years of age who attended the Fundación para el Progreso de la Medicina de Córdoba (FPM) for routine biochemical analyzes between the months of September 2021 and February 2022 were processed. rubella was determined by CMIA (ABBOTT) (FPM) while indirect immunofluorescence was performed for measles IgG at the Reina Fabiola University Clinic.
The seroprevalences found were 88.3% and 92.2% for measles and rubella, respectively. There were no significant differences between antibody concentrations by age subgroup (rubella p=0.1435, measles p=0.1049), but the antibody concentration among women was significantly higher than among men (rubella p=0.036, measles p=0.031). Among women, anti-rubella IgG was higher in the younger age subgroup (p=0.0196), but not for measles (p=0.1874) nor among age subgroups of men (rubella p=0.7445, measles p=0.1236).
The seroprevalences detected reach the coverage objective recommended by the WHO to prevent the circulation of rubella, but not the measles virus. These results show the need to sustain efforts to keep the prevalence of antibodies generated by vaccination high, also knowing that during the pandemic their application decreased, increasing the risk of virus reintroduction into the country. |
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