Seroprevalence of measles and rubella in children and adolescents aged 7 to 19 years in Córdoba, Argentina, within the framework of the control and elimination program
The immunoprevention measures (vaccination by schedule plus mass campaigns) to achieve the objectives subscribed by PAHO/WHO produced around the year 2000 a sharp drop in cases of rubella and measles in Argentina. For this reason, there is currently a young population that only has immunity through...
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| Formato: | Artículo revista |
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Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
2022
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| Acceso en línea: | https://revistas.unc.edu.ar/index.php/med/article/view/38992 |
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I10-R327-article-38992 |
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ojs |
| institution |
Universidad Nacional de Córdoba |
| institution_str |
I-10 |
| repository_str |
R-327 |
| container_title_str |
Revista de la Facultad de Ciencias Médicas de Córdoba |
| format |
Artículo revista |
| topic |
measles rubella Vaccination prevalence sarampión vacunación rubeóla prevalencia . |
| spellingShingle |
measles rubella Vaccination prevalence sarampión vacunación rubeóla prevalencia . Pedranti , M Isa , MB Riberi , M Hernández , G Alfaro , J Tenaglia , M Nates, S Adamo , MP Seroprevalence of measles and rubella in children and adolescents aged 7 to 19 years in Córdoba, Argentina, within the framework of the control and elimination program |
| topic_facet |
measles rubella Vaccination prevalence sarampión vacunación rubeóla prevalencia . |
| author |
Pedranti , M Isa , MB Riberi , M Hernández , G Alfaro , J Tenaglia , M Nates, S Adamo , MP |
| author_facet |
Pedranti , M Isa , MB Riberi , M Hernández , G Alfaro , J Tenaglia , M Nates, S Adamo , MP |
| author_sort |
Pedranti , M |
| title |
Seroprevalence of measles and rubella in children and adolescents aged 7 to 19 years in Córdoba, Argentina, within the framework of the control and elimination program |
| title_short |
Seroprevalence of measles and rubella in children and adolescents aged 7 to 19 years in Córdoba, Argentina, within the framework of the control and elimination program |
| title_full |
Seroprevalence of measles and rubella in children and adolescents aged 7 to 19 years in Córdoba, Argentina, within the framework of the control and elimination program |
| title_fullStr |
Seroprevalence of measles and rubella in children and adolescents aged 7 to 19 years in Córdoba, Argentina, within the framework of the control and elimination program |
| title_full_unstemmed |
Seroprevalence of measles and rubella in children and adolescents aged 7 to 19 years in Córdoba, Argentina, within the framework of the control and elimination program |
| title_sort |
seroprevalence of measles and rubella in children and adolescents aged 7 to 19 years in córdoba, argentina, within the framework of the control and elimination program |
| description |
The immunoprevention measures (vaccination by schedule plus mass campaigns) to achieve the objectives subscribed by PAHO/WHO produced around the year 2000 a sharp drop in cases of rubella and measles in Argentina. For this reason, there is currently a young population that only has immunity through the vaccine. Objective: Given the latent risk of reintroduction of these viruses in the country, we set out to investigate the presence of anti-rubella and anti-measles IgG antibodies in people aged 7 to 19 years who, according to the National Immunization Calendar and data from the National Surveillance Program, they should have two doses of triple viral vaccine and should not have had contact with the virus naturally.
A retrospective, descriptive cross-sectional study was conducted. 180 samples from people between 7 and 19 years of age who attended the Fundación para el Progreso de la Medicina de Córdoba (FPM) for routine biochemical analyzes between the months of September 2021 and February 2022 were processed. rubella was determined by CMIA (ABBOTT) (FPM) while indirect immunofluorescence was performed for measles IgG at the Reina Fabiola University Clinic.
The seroprevalences found were 88.3% and 92.2% for measles and rubella, respectively. There were no significant differences between antibody concentrations by age subgroup (rubella p=0.1435, measles p=0.1049), but the antibody concentration among women was significantly higher than among men (rubella p=0.036, measles p=0.031). Among women, anti-rubella IgG was higher in the younger age subgroup (p=0.0196), but not for measles (p=0.1874) nor among age subgroups of men (rubella p=0.7445, measles p=0.1236).
The seroprevalences detected reach the coverage objective recommended by the WHO to prevent the circulation of rubella, but not the measles virus. These results show the need to sustain efforts to keep the prevalence of antibodies generated by vaccination high, also knowing that during the pandemic their application decreased, increasing the risk of virus reintroduction into the country. |
| publisher |
Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología |
| publishDate |
2022 |
| url |
https://revistas.unc.edu.ar/index.php/med/article/view/38992 |
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I10-R327-article-389922024-04-15T16:14:45Z Seroprevalence of measles and rubella in children and adolescents aged 7 to 19 years in Córdoba, Argentina, within the framework of the control and elimination program Seroprevalencia de sarampión y rubéola en niños y adolescentes de 7 a 19 años de edad en Córdoba, Argentina, en el marco del programa de control y eliminación . Pedranti , M Isa , MB Riberi , M Hernández , G Alfaro , J Tenaglia , M Nates, S Adamo , MP measles rubella Vaccination prevalence sarampión vacunación rubeóla prevalencia . The immunoprevention measures (vaccination by schedule plus mass campaigns) to achieve the objectives subscribed by PAHO/WHO produced around the year 2000 a sharp drop in cases of rubella and measles in Argentina. For this reason, there is currently a young population that only has immunity through the vaccine. Objective: Given the latent risk of reintroduction of these viruses in the country, we set out to investigate the presence of anti-rubella and anti-measles IgG antibodies in people aged 7 to 19 years who, according to the National Immunization Calendar and data from the National Surveillance Program, they should have two doses of triple viral vaccine and should not have had contact with the virus naturally. A retrospective, descriptive cross-sectional study was conducted. 180 samples from people between 7 and 19 years of age who attended the Fundación para el Progreso de la Medicina de Córdoba (FPM) for routine biochemical analyzes between the months of September 2021 and February 2022 were processed. rubella was determined by CMIA (ABBOTT) (FPM) while indirect immunofluorescence was performed for measles IgG at the Reina Fabiola University Clinic. The seroprevalences found were 88.3% and 92.2% for measles and rubella, respectively. There were no significant differences between antibody concentrations by age subgroup (rubella p=0.1435, measles p=0.1049), but the antibody concentration among women was significantly higher than among men (rubella p=0.036, measles p=0.031). Among women, anti-rubella IgG was higher in the younger age subgroup (p=0.0196), but not for measles (p=0.1874) nor among age subgroups of men (rubella p=0.7445, measles p=0.1236). The seroprevalences detected reach the coverage objective recommended by the WHO to prevent the circulation of rubella, but not the measles virus. These results show the need to sustain efforts to keep the prevalence of antibodies generated by vaccination high, also knowing that during the pandemic their application decreased, increasing the risk of virus reintroduction into the country. Las medidas de inmunoprevención (vacunación por calendario más campañas masivas) para lograr los objetivos suscriptos de la OPS/OMS produjeron hacia el año 2000 una caída abrupta de casos de rubéola y sarampión en Argentina. Por este motivo, actualmente existe una población joven que sólo tiene inmunidad a través de la vacuna. Objetivo: ante el riesgo latente de reintroducción de estos virus en el país, nos propusimos investigar la presencia de anticuerpos IgG anti-rubéola y antisarampión en personas de 7 a 19 años de edad que, de acuerdo al Calendario Nacional de Inmunizaciones y los datos del Programa Nacional de Vigilancia, deberían tener dos dosis de vacuna triple viral y no deberían haber tenido contacto con el virus de manera natural. Se realizó un estudio retrospectivo, descriptivo transversal. Se procesaron 180 muestras de personas de entre 7 y 19 años de edad que concurrieron a realizarse análisis bioquímicos de rutina a la Fundación para el Progreso de la Medicina de Córdoba (FPM) entre los meses de septiembre de 2021 y febrero de 2022. La IgG rubéola se determinó por CMIA (ABBOTT) (FPM) mientras que para IgG sarampión se realizó inmunofluorescencia indirecta en la Clínica Universitaria Reina Fabiola. Las seroprevalencias encontradas fueron del 88.3% y 92.2% para sarampión y rubéola respectivamente. No hubo diferencias significativas entre concentraciones de anticuerpos por subgrupo etario (rubéola p=0.1435, sarampión p=0.1049), pero la concentración de anticuerpos entre mujeres fue significativamente mayor que entre hombres (rubéola p=0.036, sarampión p=0.031). Entre mujeres la IgG anti-rubéola fue mayor en el subgrupo etario de menor edad (p=0.0196), no así para sarampión (p=0.1874) ni entre subgrupos etarios de hombres (rubéola p=0.7445, sarampión p=0.1236). Las seroprevalencias detectadas alcanzan el objetivo de cobertura recomendado por la OMS para impedir la circulación de rubéola, no así de virus sarampión. Estos resultados evidencian la necesidad de sostener los esfuerzos para mantener elevadas las prevalencias de anticuerpos generados por la vacunación, sabiendo además que durante la pandemia bajó la aplicación de las mismas, aumentando el riesgo de reintroducción de los virus en el país. . Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2022-10-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion texto texto . https://revistas.unc.edu.ar/index.php/med/article/view/38992 Revista de la Facultad de Ciencias Médicas de Córdoba.; Vol. 79 No. Suplemento JIC XXIII (2022): Suplemento JIC XXIII Revista de la Facultad de Ciencias Médicas de Córdoba; Vol. 79 Núm. Suplemento JIC XXIII (2022): Suplemento JIC XXIII Revista da Faculdade de Ciências Médicas de Córdoba; v. 79 n. Suplemento JIC XXIII (2022): Suplemento JIC XXIII 1853-0605 0014-6722 http://creativecommons.org/licenses/by-nc/4.0 |