Conformity of commercial bleachers and stability of 1g/l dilutions using different drinking water sources

Bleach, known as Sodium Hypochlorite (HS) solution, is a broad-spectrum, fast-acting, widely available germicidal agent that is key in infection control. In the context of COVID-19, the WHO recommends the use of HS 1 g/L, since it inactivates SARS-CoV-2 and most environmental pathogens. However, few...

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Autores principales: GAVELLI, ME, LUCIANI GIACOBBE, LC, BUSTOS FIERRO, C, OLIVERA, ME
Formato: Artículo revista
Publicado: Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2022
Materias:
Sodium Hypochlorite
Study the Stability
Active chlorine
lavandina
hipoclorito de sodio
estudio de estabilidad
Acceso en línea:https://revistas.unc.edu.ar/index.php/med/article/view/38985
Aporte de:
Revista de la Facultad de Ciencias Médicas de Córdoba de Universidad Nacional de Córdoba
id I10-R327-article-38985
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institution Universidad Nacional de Córdoba
institution_str I-10
repository_str R-327
container_title_str Revista de la Facultad de Ciencias Médicas de Córdoba
format Artículo revista
topic Sodium Hypochlorite
Study the Stability
Active chlorine
lavandina
hipoclorito de sodio
estudio de estabilidad
spellingShingle Sodium Hypochlorite
Study the Stability
Active chlorine
lavandina
hipoclorito de sodio
estudio de estabilidad
GAVELLI, ME
LUCIANI GIACOBBE, LC
BUSTOS FIERRO, C
OLIVERA, ME
Conformity of commercial bleachers and stability of 1g/l dilutions using different drinking water sources
topic_facet Sodium Hypochlorite
Study the Stability
Active chlorine
lavandina
hipoclorito de sodio
estudio de estabilidad
author GAVELLI, ME
LUCIANI GIACOBBE, LC
BUSTOS FIERRO, C
OLIVERA, ME
author_facet GAVELLI, ME
LUCIANI GIACOBBE, LC
BUSTOS FIERRO, C
OLIVERA, ME
author_sort GAVELLI, ME
title Conformity of commercial bleachers and stability of 1g/l dilutions using different drinking water sources
title_short Conformity of commercial bleachers and stability of 1g/l dilutions using different drinking water sources
title_full Conformity of commercial bleachers and stability of 1g/l dilutions using different drinking water sources
title_fullStr Conformity of commercial bleachers and stability of 1g/l dilutions using different drinking water sources
title_full_unstemmed Conformity of commercial bleachers and stability of 1g/l dilutions using different drinking water sources
title_sort conformity of commercial bleachers and stability of 1g/l dilutions using different drinking water sources
description Bleach, known as Sodium Hypochlorite (HS) solution, is a broad-spectrum, fast-acting, widely available germicidal agent that is key in infection control. In the context of COVID-19, the WHO recommends the use of HS 1 g/L, since it inactivates SARS-CoV-2 and most environmental pathogens. However, few studies evaluate the stability of diluted solutions and none consider the influence of the hardness of the water used for their preparation. The objective of the work was to verify the concentration of active chlorine (ACC) in commercial brands of HS and to study the stability to propose a beyond use date (BDU) for solutions of HS 1 g/L, with drinking water from different sources. The CCA was determined as a function of time (by iodometric titration) in 5 different commercial preparations (nominal concentration between 25-60 g/L) and in dilutions of 1 g/L (in triplicate), using water from different water treatment plants in Córdoba, Argentina. The samples were stored at room temperature, exposed and protected from light. The BUD was reached when the CCA fell below 90% of the initial. Assays were performed in triplicate and are reported as the mean (±SD). The CCA in the commercial solutions was within the acceptable values, as established in the current regulations. Light-protected dilutions showed less than a 10% decrease in CCA during the first 10 days of testing, and one sample exceeded the acceptance limit after 14 days. In contrast, in the light-exposed sample, the CCA fell to 96.4% at 24 hours and 79.3% after 48 hours. No differences related to drinking water sources were observed. The nominal CCA was confirmed in all commercial brands tested. Regardless of the drinking water source used for dilution, 1 g/L HS solutions were stable for 10 days when stored at room temperature and protected from light. In contrast, light-exposed solutions maintain CCA for only 24 hours.
publisher Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
publishDate 2022
url https://revistas.unc.edu.ar/index.php/med/article/view/38985
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spelling I10-R327-article-389852024-04-15T16:14:45Z Conformity of commercial bleachers and stability of 1g/l dilutions using different drinking water sources Conformidad de lavandinas comerciales y estabilidad de diluciones 1g/l utilizando diferentes fuentes de agua potable GAVELLI, ME LUCIANI GIACOBBE, LC BUSTOS FIERRO, C OLIVERA, ME Sodium Hypochlorite Study the Stability Active chlorine lavandina hipoclorito de sodio estudio de estabilidad Bleach, known as Sodium Hypochlorite (HS) solution, is a broad-spectrum, fast-acting, widely available germicidal agent that is key in infection control. In the context of COVID-19, the WHO recommends the use of HS 1 g/L, since it inactivates SARS-CoV-2 and most environmental pathogens. However, few studies evaluate the stability of diluted solutions and none consider the influence of the hardness of the water used for their preparation. The objective of the work was to verify the concentration of active chlorine (ACC) in commercial brands of HS and to study the stability to propose a beyond use date (BDU) for solutions of HS 1 g/L, with drinking water from different sources. The CCA was determined as a function of time (by iodometric titration) in 5 different commercial preparations (nominal concentration between 25-60 g/L) and in dilutions of 1 g/L (in triplicate), using water from different water treatment plants in Córdoba, Argentina. The samples were stored at room temperature, exposed and protected from light. The BUD was reached when the CCA fell below 90% of the initial. Assays were performed in triplicate and are reported as the mean (±SD). The CCA in the commercial solutions was within the acceptable values, as established in the current regulations. Light-protected dilutions showed less than a 10% decrease in CCA during the first 10 days of testing, and one sample exceeded the acceptance limit after 14 days. In contrast, in the light-exposed sample, the CCA fell to 96.4% at 24 hours and 79.3% after 48 hours. No differences related to drinking water sources were observed. The nominal CCA was confirmed in all commercial brands tested. Regardless of the drinking water source used for dilution, 1 g/L HS solutions were stable for 10 days when stored at room temperature and protected from light. In contrast, light-exposed solutions maintain CCA for only 24 hours. La lavandina, conocida como solución de Hipoclorito de Sodio (HS), es un agente germicida de amplio espectro, rápida acción, ampliamente disponible y clave en el control de infecciones. En el contexto de COVID-19, la OMS recomienda el uso de HS 1 g/L, ya que inactiva al SARS-CoV-2 y a la mayoría de patógenos del entorno. Sin embargo, escasos estudios evalúan la estabilidad de las soluciones diluidas y ninguno considera la influencia de la dureza del agua utilizada para su preparación. El objetivo del trabajo fue verificar la concentración de cloro activo (CCA) en marcas comerciales de HS y estudiar la estabilidad para proponer una fecha límite de uso (FLU) para soluciones de HS 1 g/L, con agua potable proveniente de diferentes fuentes. Se determinó la CCA en función del tiempo (mediante titulación iodométrica) en 5 preparaciones comerciales diferentes (concentración nominal entre 25-60 g/L) y en diluciones de 1 g/L (por triplicado), usando agua de diferentes plantas potabilizadoras de Córdoba, Argentina. Las muestras se almacenaron a temperatura ambiente, expuestas y protegidas de la luz. La FLU se alcanzó cuando la CCA cayó por debajo del 90% de la inicial. Los ensayos se realizaron por triplicado y se informan como la media (±DE). La CCA en las soluciones comerciales estuvo dentro de los valores aceptables, según lo establecido en la normativa vigente. Las diluciones protegidas de la luz mostraron una disminución menor al 10% en la CCA, durante los primeros 10 días de ensayo y una muestra superó el límite de aceptación luego de 14 días. En contraste, en la muestra expuesta a la luz, la CCA cayó a 96.4% a las 24 horas y 79.3% después de 48 horas. No se observaron diferencias relacionadas con las fuentes de agua potable. Se confirmó la CCA nominal en todas las marcas comerciales evaluadas. Independientemente de la fuente de agua potable utilizada para la dilución, las soluciones de HS 1 g/L fueron estables durante 10 días cuando se almacenaron a temperatura ambiente y protegidas de la luz. En contraste, las soluciones expuestas a la luz mantienen la CCA solo 24 horas. Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2022-10-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion . https://revistas.unc.edu.ar/index.php/med/article/view/38985 Revista de la Facultad de Ciencias Médicas de Córdoba.; Vol. 79 No. Suplemento JIC XXIII (2022): Suplemento JIC XXIII Revista de la Facultad de Ciencias Médicas de Córdoba; Vol. 79 Núm. Suplemento JIC XXIII (2022): Suplemento JIC XXIII Revista da Faculdade de Ciências Médicas de Córdoba; v. 79 n. Suplemento JIC XXIII (2022): Suplemento JIC XXIII 1853-0605 0014-6722 http://creativecommons.org/licenses/by-nc/4.0

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