Influence of tobacco smoke in pediatric patients and young adult asthmatics in the province of Cordoba

Bronchial asthma is a chronic inflammatory disorder of the lower respiratory tract that causes symptoms such as wheezing, dyspnea, chest tightness and cough that vary over time in their appearance, frequency and intensity. It has been proposed that several genes with variable effects participate in...

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Detalles Bibliográficos
Autores principales: Liendo , AI, Pereira , BMI, Rodriguez , M, Skrie, V, Orellana , J
Formato: Artículo revista
Publicado: Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2022
Materias:
.
Acceso en línea:https://revistas.unc.edu.ar/index.php/med/article/view/38942
Aporte de:
id I10-R327-article-38942
record_format ojs
institution Universidad Nacional de Córdoba
institution_str I-10
repository_str R-327
container_title_str Revista de la Facultad de Ciencias Médicas de Córdoba
format Artículo revista
topic Asthma
tobacco
Pediatrics
atopy
asma
tabaco
Pediatría
atopia
.
spellingShingle Asthma
tobacco
Pediatrics
atopy
asma
tabaco
Pediatría
atopia
.
Liendo , AI
Pereira , BMI
Rodriguez , M
Skrie, V
Orellana , J
Influence of tobacco smoke in pediatric patients and young adult asthmatics in the province of Cordoba
topic_facet Asthma
tobacco
Pediatrics
atopy
asma
tabaco
Pediatría
atopia
.
author Liendo , AI
Pereira , BMI
Rodriguez , M
Skrie, V
Orellana , J
author_facet Liendo , AI
Pereira , BMI
Rodriguez , M
Skrie, V
Orellana , J
author_sort Liendo , AI
title Influence of tobacco smoke in pediatric patients and young adult asthmatics in the province of Cordoba
title_short Influence of tobacco smoke in pediatric patients and young adult asthmatics in the province of Cordoba
title_full Influence of tobacco smoke in pediatric patients and young adult asthmatics in the province of Cordoba
title_fullStr Influence of tobacco smoke in pediatric patients and young adult asthmatics in the province of Cordoba
title_full_unstemmed Influence of tobacco smoke in pediatric patients and young adult asthmatics in the province of Cordoba
title_sort influence of tobacco smoke in pediatric patients and young adult asthmatics in the province of cordoba
description Bronchial asthma is a chronic inflammatory disorder of the lower respiratory tract that causes symptoms such as wheezing, dyspnea, chest tightness and cough that vary over time in their appearance, frequency and intensity. It has been proposed that several genes with variable effects participate in its pathogenesis, as well as environmental factors, and the interaction between them modulates the clinical expression of asthma both at the beginning and in the course of the disease. Atopy is the most important identifiable predisposing factor for this disease. Environmental factors and lifestyle have been suggested as modulators in the development of atopy. Among the environmental factors, exposure to tobacco stands out, as well as exposure and sensitization to aeroallergens. There is currently no information available on how these factors influence the asthmatic pediatric population in the province of Córdoba. With the aim of analyzing the influence of exposure to tobacco and the place of residence in asthmatic patients, correlating them fundamentally with their levels of Immunoglobulin E (IgE), 65 patients with a diagnosis of allergic bronchial asthma of the Division of Allergy and Immunology of the Children's Hospital of the Holy Trinity. The data was collected from the medical records compiled in the Division and analyzed statistically. No statistically significant relationship was observed between high levels of IgE (NV = 0 to 200 IU/ml) with exposure to tobacco smoke, or with the place of origin. The influence of these factors in the development and evolution of the disease is not ruled out. We propose that as it is a multifactorial disease, various genetic and environmental factors must be analyzed in order to reach conclusions that contribute to the epidemiology of this disease and that would help the treatment and follow-up of these patients.
publisher Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
publishDate 2022
url https://revistas.unc.edu.ar/index.php/med/article/view/38942
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spelling I10-R327-article-389422024-04-15T16:14:45Z Influence of tobacco smoke in pediatric patients and young adult asthmatics in the province of Cordoba Influencia del humo de tabaco en pacientes pediátricos y adultos jóvenes asmáticos de la provincia de Córdoba . Liendo , AI Pereira , BMI Rodriguez , M Skrie, V Orellana , J Asthma tobacco Pediatrics atopy asma tabaco Pediatría atopia . Bronchial asthma is a chronic inflammatory disorder of the lower respiratory tract that causes symptoms such as wheezing, dyspnea, chest tightness and cough that vary over time in their appearance, frequency and intensity. It has been proposed that several genes with variable effects participate in its pathogenesis, as well as environmental factors, and the interaction between them modulates the clinical expression of asthma both at the beginning and in the course of the disease. Atopy is the most important identifiable predisposing factor for this disease. Environmental factors and lifestyle have been suggested as modulators in the development of atopy. Among the environmental factors, exposure to tobacco stands out, as well as exposure and sensitization to aeroallergens. There is currently no information available on how these factors influence the asthmatic pediatric population in the province of Córdoba. With the aim of analyzing the influence of exposure to tobacco and the place of residence in asthmatic patients, correlating them fundamentally with their levels of Immunoglobulin E (IgE), 65 patients with a diagnosis of allergic bronchial asthma of the Division of Allergy and Immunology of the Children's Hospital of the Holy Trinity. The data was collected from the medical records compiled in the Division and analyzed statistically. No statistically significant relationship was observed between high levels of IgE (NV = 0 to 200 IU/ml) with exposure to tobacco smoke, or with the place of origin. The influence of these factors in the development and evolution of the disease is not ruled out. We propose that as it is a multifactorial disease, various genetic and environmental factors must be analyzed in order to reach conclusions that contribute to the epidemiology of this disease and that would help the treatment and follow-up of these patients. El asma bronquial es un trastorno inflamatorio crónico de las vías respiratorias inferiores que provoca síntomas tales como respiración sibilante, disnea, opresión torácica y tos que varían con el tiempo en su aparición, frecuencia e intensidad. Se ha propuesto que en su patogénesis participan varios genes con efectos variables al igual que factores ambientales, y la interacción entre los mismos modulan la expresión clínica del asma tanto en el comienzo como en la evolución de la enfermedad. La atopia es el factor predisponente identificable más importante de esta enfermedad. Los factores ambientales y el estilo de vida se han sugerido como moduladores en el desarrollo de atopia. Dentro de los factores ambientales se destacan la exposición al tabaco, tanto como la exposición y sensibilización a aeroalérgenos. Actualmente no se dispone de información de cómo estos factores influyen en la población pediátrica asmática de la provincia de Córdoba. Con el objetivo de analizar la influencia de la exposición al tabaco y el lugar de residencia en los pacientes asmáticos, correlacionándolos fundamentalmente con sus niveles de Inmunoglobulina E (IgE), se estudiaron 65 pacientes con diagnóstico de asma bronquial alérgico de la División de Alergia e inmunología del Hospital de Niños de la Santísima Trinidad. Los datos se recolectaron a partir de las historias clínicas confeccionadas en la División y se analizaron de manera estadística. No se observó una relación estadísticamente significativa entre niveles elevados de IgE (VN = 0 a 200 UI/ml) con la exposición al humo de tabaco, ni con el lugar de procedencia. No se descarta la influencia de estos factores en el desarrollo y evolución de la enfermedad. Proponemos que al ser una enfermedad multifactorial, deben de analizarse diversos factores tantos genéticos como ambientales para poder arribar a conclusiones que aporten a la epidemiologia de esta enfermedad y que ayudarían al tratamiento y seguimiento de estos pacientes. . Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2022-10-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion texto texto . https://revistas.unc.edu.ar/index.php/med/article/view/38942 Revista de la Facultad de Ciencias Médicas de Córdoba.; Vol. 79 No. Suplemento JIC XXIII (2022): Suplemento JIC XXIII Revista de la Facultad de Ciencias Médicas de Córdoba; Vol. 79 Núm. Suplemento JIC XXIII (2022): Suplemento JIC XXIII Revista da Faculdade de Ciências Médicas de Córdoba; v. 79 n. Suplemento JIC XXIII (2022): Suplemento JIC XXIII 1853-0605 0014-6722 http://creativecommons.org/licenses/by-nc/4.0