Skin lesions associated with invasive candidiasis in a neutropenic patient with acute myeloid leukemia

A 51-year-old male with profound and prolonged neutropenia 12 days after receiving chemotherapy for an acute myeloid leukemia developed a nodular, erythematous lesion with a necrotic center on the base of the neck, associated with fever, chills, and myalgia. An invasive fungal infection was diagnose...

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Detalles Bibliográficos
Autores principales: Santarelli, Ignacio Martín, Brest, Agustín, Juri, Pablo Jorge, Grinspun, Martin, Fernández, Sofía Isabel
Formato: Artículo revista
Lenguaje:Español
Publicado: Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2023
Materias:
Candida
neutropenia
skin
piel
pele
Acceso en línea:https://revistas.unc.edu.ar/index.php/med/article/view/38723
Aporte de:
Revista de la Facultad de Ciencias Médicas de Córdoba de Universidad Nacional de Córdoba
id I10-R327-article-38723
record_format ojs
spelling I10-R327-article-387232023-07-10T12:07:38Z Skin lesions associated with invasive candidiasis in a neutropenic patient with acute myeloid leukemia Lesiones cutáneas asociadas a candidiasis invasiva en un paciente neutropénico con leucemia mieloide aguda Lesões cutâneas associadas à candidíase invasiva em paciente neutropênico com leucemia mieloide aguda Santarelli, Ignacio Martín Brest, Agustín Juri, Pablo Jorge Grinspun, Martin Fernández, Sofía Isabel Candida neutropenia skin Candida neutropenia piel Candida neutropenia pele A 51-year-old male with profound and prolonged neutropenia 12 days after receiving chemotherapy for an acute myeloid leukemia developed a nodular, erythematous lesion with a necrotic center on the base of the neck, associated with fever, chills, and myalgia. An invasive fungal infection was diagnosed after growth of Candia tropicalis in blood cultures. He evolved with multiple reddish papular lesions concentrated mainly on the trunk, although they also spread to the extremities. The most common skin lesions of disseminated candidiasis are erythematous-violaceous papules with vesicular centers, which, in some cases, can progress to necrosis. Other forms of cutaneous presentation of invasive candidiasis are ecthyma gangrenosum-like lesions, hemorrhagic plaques or bullae, rash resembling folliculitis, and subcutaneous nodules. Un varón de 51 años que se encontraba con neutropenia profunda y prolongada luego de 12 días del inicio de su quimioterapia por una leucemia mieloide aguda desarrolló una lesión nodular, eritematosa y con centro necrótico en la base del cuello, asociada a fiebre, escalofríos y mialgias. Se diagnosticó infección fúngica invasiva luego del desarrollo de Candia tropicalis en los hemocultivos. Evolucionó con múltiples lesiones papulares rojizas concentradas principalmente en el tronco, aunque también extendidas a las extremidades. Las lesiones cutáneas más frecuentes de la candidiasis diseminada son pápulas eritematosas-violáceas con centros vesiculares, que, en algunos casos, pueden evolucionar a necrosis. Otras formas de presentación cutánea de la candidiasis invasiva son lesiones similares a ectima gangrenoso, placas o bullas hemorrágicas, erupción que resembla foliculitis, y nódulos subcutáneos. Um homem de 51 anos com neutropenia profunda e prolongada 12 dias após o início da quimioterapia para leucemia mieloide aguda desenvolveu lesão nodular eritematosa com centro necrótico na base do pescoço, associada a febre, calafrios e mialgia. A infecção fúngica invasiva foi diagnosticada após o desenvolvimento de Candia tropicalis em hemoculturas. Evoluiu com múltiplas lesões papulares avermelhadas concentradas principalmente no tronco, embora também se espalhassem para as extremidades. As lesões cutâneas mais comuns da candidíase disseminada são as pápulas eritêmato-violáceas com centros vesiculares, que, em alguns casos, podem evoluir para necrose. Outras formas de apresentação cutânea da candidíase invasiva são lesões semelhantes ao ectima gangrenoso, placas ou bolhas hemorrágicas, erupção cutânea semelhante à foliculite e nódulos subcutâneos. Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2023-06-30 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Text Texto Texto application/pdf text/html https://revistas.unc.edu.ar/index.php/med/article/view/38723 10.31053/1853.0605.v80.n2.38723 Revista de la Facultad de Ciencias Médicas de Córdoba.; Vol. 80 No. 2 (2023); 158-159 Revista de la Facultad de Ciencias Médicas de Córdoba; Vol. 80 Núm. 2 (2023); 158-159 Revista da Faculdade de Ciências Médicas de Córdoba; v. 80 n. 2 (2023); 158-159 1853-0605 0014-6722 10.31053/1853.0605.v80.n2 spa https://revistas.unc.edu.ar/index.php/med/article/view/38723/41770 https://revistas.unc.edu.ar/index.php/med/article/view/38723/41148 Derechos de autor 2023 Universidad Nacional de Córdoba http://creativecommons.org/licenses/by-nc/4.0
institution Universidad Nacional de Córdoba
institution_str I-10
repository_str R-327
container_title_str Revista de la Facultad de Ciencias Médicas de Córdoba
language Español
format Artículo revista
topic Candida
neutropenia
skin
Candida
neutropenia
piel
Candida
neutropenia
pele
spellingShingle Candida
neutropenia
skin
Candida
neutropenia
piel
Candida
neutropenia
pele
Santarelli, Ignacio Martín
Brest, Agustín
Juri, Pablo Jorge
Grinspun, Martin
Fernández, Sofía Isabel
Skin lesions associated with invasive candidiasis in a neutropenic patient with acute myeloid leukemia
topic_facet Candida
neutropenia
skin
Candida
neutropenia
piel
Candida
neutropenia
pele
author Santarelli, Ignacio Martín
Brest, Agustín
Juri, Pablo Jorge
Grinspun, Martin
Fernández, Sofía Isabel
author_facet Santarelli, Ignacio Martín
Brest, Agustín
Juri, Pablo Jorge
Grinspun, Martin
Fernández, Sofía Isabel
author_sort Santarelli, Ignacio Martín
title Skin lesions associated with invasive candidiasis in a neutropenic patient with acute myeloid leukemia
title_short Skin lesions associated with invasive candidiasis in a neutropenic patient with acute myeloid leukemia
title_full Skin lesions associated with invasive candidiasis in a neutropenic patient with acute myeloid leukemia
title_fullStr Skin lesions associated with invasive candidiasis in a neutropenic patient with acute myeloid leukemia
title_full_unstemmed Skin lesions associated with invasive candidiasis in a neutropenic patient with acute myeloid leukemia
title_sort skin lesions associated with invasive candidiasis in a neutropenic patient with acute myeloid leukemia
description A 51-year-old male with profound and prolonged neutropenia 12 days after receiving chemotherapy for an acute myeloid leukemia developed a nodular, erythematous lesion with a necrotic center on the base of the neck, associated with fever, chills, and myalgia. An invasive fungal infection was diagnosed after growth of Candia tropicalis in blood cultures. He evolved with multiple reddish papular lesions concentrated mainly on the trunk, although they also spread to the extremities. The most common skin lesions of disseminated candidiasis are erythematous-violaceous papules with vesicular centers, which, in some cases, can progress to necrosis. Other forms of cutaneous presentation of invasive candidiasis are ecthyma gangrenosum-like lesions, hemorrhagic plaques or bullae, rash resembling folliculitis, and subcutaneous nodules.
publisher Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
publishDate 2023
url https://revistas.unc.edu.ar/index.php/med/article/view/38723
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first_indexed 2024-09-03T21:03:43Z
last_indexed 2024-09-03T21:03:43Z
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