Chemotherapy at the end of life is compatible with dignified death and palliative care
Introduction: Cancer treatment is increasingly aggressive. The aim was to estimate who died due to cancer, to report use of chemotherapy (CT) in the last 3 months of life, and to describe clinical-epidemiological characteristics of these patients. Methods: We included a consecutive sample of decease...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Artículo revista |
| Lenguaje: | Español |
| Publicado: |
Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
2023
|
| Materias: | |
| Acceso en línea: | https://revistas.unc.edu.ar/index.php/med/article/view/37489 |
| Aporte de: |
| id |
I10-R327-article-37489 |
|---|---|
| record_format |
ojs |
| institution |
Universidad Nacional de Córdoba |
| institution_str |
I-10 |
| repository_str |
R-327 |
| container_title_str |
Revista de la Facultad de Ciencias Médicas de Córdoba |
| language |
Español |
| format |
Artículo revista |
| topic |
medical oncology drug therapy palliative care death oncología médica quimioterapia cuidados paliativos muerte oncologia tratamento farmacológico morte cuidados Paliativos |
| spellingShingle |
medical oncology drug therapy palliative care death oncología médica quimioterapia cuidados paliativos muerte oncologia tratamento farmacológico morte cuidados Paliativos Diaz, Mario Hernan Ibañez Ledesma, Luz Guadalupe Torres Gomez, Felipe Carretero, Marcelina Pasquinelli, Rosario Martínez, Bernardo Julio Grande Ratti, María Florencia Chemotherapy at the end of life is compatible with dignified death and palliative care |
| topic_facet |
medical oncology drug therapy palliative care death oncología médica quimioterapia cuidados paliativos muerte oncologia tratamento farmacológico morte cuidados Paliativos |
| author |
Diaz, Mario Hernan Ibañez Ledesma, Luz Guadalupe Torres Gomez, Felipe Carretero, Marcelina Pasquinelli, Rosario Martínez, Bernardo Julio Grande Ratti, María Florencia |
| author_facet |
Diaz, Mario Hernan Ibañez Ledesma, Luz Guadalupe Torres Gomez, Felipe Carretero, Marcelina Pasquinelli, Rosario Martínez, Bernardo Julio Grande Ratti, María Florencia |
| author_sort |
Diaz, Mario Hernan |
| title |
Chemotherapy at the end of life is compatible with dignified death and palliative care |
| title_short |
Chemotherapy at the end of life is compatible with dignified death and palliative care |
| title_full |
Chemotherapy at the end of life is compatible with dignified death and palliative care |
| title_fullStr |
Chemotherapy at the end of life is compatible with dignified death and palliative care |
| title_full_unstemmed |
Chemotherapy at the end of life is compatible with dignified death and palliative care |
| title_sort |
chemotherapy at the end of life is compatible with dignified death and palliative care |
| description |
Introduction: Cancer treatment is increasingly aggressive. The aim was to estimate who died due to cancer, to report use of chemotherapy (CT) in the last 3 months of life, and to describe clinical-epidemiological characteristics of these patients.
Methods: We included a consecutive sample of deceased during 2017, affiliated to Hospital Italiano de Buenos Aires. Through manual review of medical helath records, they were classified according to the cause of death (cancer or other cause), validating diagnosis and baseline stage, performance status (PS). Prevalences with 95% CI are reported and descriptive statistics were used.
Results: A total of 2293 adults died, 59% women with a median age of 84 years old. There were a total of 736 deaths from cancer, representing 32% (95%CI 30-34). This last subgroup were 54% women, with a median age of 75 years, and only one patient had advance directives. Regarding the place of death, 80% were hospitalized (65% general ward and 15% intensive care units). The most frequent tumors were: lung, colorectal-gastric, hematological, and breast. A total of 390 patients received CT at the end of life (53%; 95%CI 49-57), 53% being women and with a mean age of 68 years. Regarding the underlying oncological disease: 81% had a solid tumor, 75% advanced stage, and mostly with poor/regular ability to perform daily activities (25% PS3 and 32% PS4, respectively).
Conclusion: There is a high frequency of CT at the end of life and deaths continue to be mainly in-hospital. |
| publisher |
Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología |
| publishDate |
2023 |
| url |
https://revistas.unc.edu.ar/index.php/med/article/view/37489 |
| work_keys_str_mv |
AT diazmariohernan chemotherapyattheendoflifeiscompatiblewithdignifieddeathandpalliativecare AT ibanezledesmaluzguadalupe chemotherapyattheendoflifeiscompatiblewithdignifieddeathandpalliativecare AT torresgomezfelipe chemotherapyattheendoflifeiscompatiblewithdignifieddeathandpalliativecare AT carreteromarcelina chemotherapyattheendoflifeiscompatiblewithdignifieddeathandpalliativecare AT pasquinellirosario chemotherapyattheendoflifeiscompatiblewithdignifieddeathandpalliativecare AT martinezbernardojulio chemotherapyattheendoflifeiscompatiblewithdignifieddeathandpalliativecare AT granderattimariaflorencia chemotherapyattheendoflifeiscompatiblewithdignifieddeathandpalliativecare AT diazmariohernan quimioterapiaalfinaldelavidaescompatibleconmuertedignaycuidadospaliativos AT ibanezledesmaluzguadalupe quimioterapiaalfinaldelavidaescompatibleconmuertedignaycuidadospaliativos AT torresgomezfelipe quimioterapiaalfinaldelavidaescompatibleconmuertedignaycuidadospaliativos AT carreteromarcelina quimioterapiaalfinaldelavidaescompatibleconmuertedignaycuidadospaliativos AT pasquinellirosario quimioterapiaalfinaldelavidaescompatibleconmuertedignaycuidadospaliativos AT martinezbernardojulio quimioterapiaalfinaldelavidaescompatibleconmuertedignaycuidadospaliativos AT granderattimariaflorencia quimioterapiaalfinaldelavidaescompatibleconmuertedignaycuidadospaliativos AT diazmariohernan aquimioterapianofimdavidaecompativelcommortedignificaecuidadospaliativos AT ibanezledesmaluzguadalupe aquimioterapianofimdavidaecompativelcommortedignificaecuidadospaliativos AT torresgomezfelipe aquimioterapianofimdavidaecompativelcommortedignificaecuidadospaliativos AT carreteromarcelina aquimioterapianofimdavidaecompativelcommortedignificaecuidadospaliativos AT pasquinellirosario aquimioterapianofimdavidaecompativelcommortedignificaecuidadospaliativos AT martinezbernardojulio aquimioterapianofimdavidaecompativelcommortedignificaecuidadospaliativos AT granderattimariaflorencia aquimioterapianofimdavidaecompativelcommortedignificaecuidadospaliativos |
| first_indexed |
2024-09-03T21:03:36Z |
| last_indexed |
2024-09-03T21:03:36Z |
| _version_ |
1809210321479401472 |
| spelling |
I10-R327-article-374892023-07-26T15:14:45Z Chemotherapy at the end of life is compatible with dignified death and palliative care Quimioterapia al final de la vida es compatible con muerte digna y cuidados paliativos A quimioterapia no fim da vida é compatível com morte dignifica e cuidados paliativos Diaz, Mario Hernan Ibañez Ledesma, Luz Guadalupe Torres Gomez, Felipe Carretero, Marcelina Pasquinelli, Rosario Martínez, Bernardo Julio Grande Ratti, María Florencia medical oncology drug therapy palliative care death oncología médica quimioterapia cuidados paliativos muerte oncologia tratamento farmacológico morte cuidados Paliativos Introduction: Cancer treatment is increasingly aggressive. The aim was to estimate who died due to cancer, to report use of chemotherapy (CT) in the last 3 months of life, and to describe clinical-epidemiological characteristics of these patients. Methods: We included a consecutive sample of deceased during 2017, affiliated to Hospital Italiano de Buenos Aires. Through manual review of medical helath records, they were classified according to the cause of death (cancer or other cause), validating diagnosis and baseline stage, performance status (PS). Prevalences with 95% CI are reported and descriptive statistics were used. Results: A total of 2293 adults died, 59% women with a median age of 84 years old. There were a total of 736 deaths from cancer, representing 32% (95%CI 30-34). This last subgroup were 54% women, with a median age of 75 years, and only one patient had advance directives. Regarding the place of death, 80% were hospitalized (65% general ward and 15% intensive care units). The most frequent tumors were: lung, colorectal-gastric, hematological, and breast. A total of 390 patients received CT at the end of life (53%; 95%CI 49-57), 53% being women and with a mean age of 68 years. Regarding the underlying oncological disease: 81% had a solid tumor, 75% advanced stage, and mostly with poor/regular ability to perform daily activities (25% PS3 and 32% PS4, respectively). Conclusion: There is a high frequency of CT at the end of life and deaths continue to be mainly in-hospital. Introducción: El tratamiento oncológico es cada vez más agresivo. El objetivo de este trabajo fue estimar las personas fallecidas por causa oncológica, reportar la frecuencia de uso de quimioterapia (QT) en los últimos 3 meses de vida, y describir las características clínicas-epidemiológicas de estos pacientes. Métodos: Se incluyó una muestra consecutiva de fallecidos durante el 2017, afiliados a prepaga del Hospital Italiano de Buenos Aires. Mediante revisión de historias clínicas, se los clasificó según la causa de muerte (oncológico u otra causa), validando diagnóstico y estadio de base, performance status (PS). Se reportan prevalencias con IC95% y se utilizó estadística descriptiva. Resultados: Fallecieron 2293 personas, 59% mujeres con mediana de 84 años. Hubo un total de 736 fallecidos por cáncer, representando el 32% (IC95% 30-34). Este último subgrupo presentó una mediana de 75 años, 54% eran mujeres y sólo una paciente tenía directivas anticipadas. En cuanto al lugar de fallecimiento, 80% ocurrió hospitalizado (65% sala general y 15% unidad cerrada). Los tumores más frecuentes fueron: pulmón, colorrectal-gástrico, hematológico, y mama. Un total de 390 pacientes recibieron QT al final de la vida (53%; IC95% 49-57), siendo 53% mujeres y con promedio de 68 años. En cuanto a la enfermedad oncológica de base: 81% tenían tumor sólido, 75% estadío avanzado, y mayoritariamente con mala/regular capacidad para realizar actividades cotidianas (25% PS3 y 32% PS4 respectivamente). Conclusión: Existe una frecuencia preocupante del uso de QT en el fin de vida y los fallecimientos siguen siendo principalmente intrahospitalarios. Introdução: O tratamento do câncer está cada vez mais agressivo. O objetivo deste estudo foi estimar o número de pessoas que morreram por câncer, relatar a frequência de uso de quimioterapia (TC) nos últimos 3 meses de vida e descrever as características clínico-epidemiológicas desses pacientes. Métodos: Foi incluída uma amostra consecutiva de falecidos durante 2017, filiados ao Hospital Italiano de Buenos Aires pré-pago. Por meio de revisão de prontuários, eles foram classificados de acordo com a causa da morte (câncer ou outra causa), validando diagnóstico e estágio inicial, performance status (PS). Prevalências com IC 95% são relatadas e estatística descritiva foi utilizada. Resultados: 2.293 pessoas morreram, 59% mulheres com idade mediana de 84 anos. Houve um total de 736 mortes por câncer, representando 32% (IC 95% 30-34). Este último subgrupo tinha idade mediana de 75 anos, 54% eram mulheres e apenas um paciente possuía diretivas antecipadas de vontade. Em relação ao local do óbito, 80% foram internados (65% enfermaria geral e 15% unidade fechada). Os tumores mais frequentes foram: pulmão, colorretal-gástrico, hematológico e de mama. Um total de 390 pacientes recebeu TC no final da vida (53%; IC 95% 49-57), sendo 53% mulheres e com idade média de 68 anos. Em relação à doença oncológica de base: 81% apresentavam tumor sólido, 75% em estágio avançado e a maioria com capacidade ruim/regular para realizar atividades diárias (25% PS3 e 32% PS4, respectivamente). Conclusão: Existe uma frequência preocupante do uso de TC no final da vida e os óbitos continuam sendo principalmente intra-hospitalares. Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2023-06-30 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf text/html https://revistas.unc.edu.ar/index.php/med/article/view/37489 10.31053/1853.0605.v80.n2.37489 Revista de la Facultad de Ciencias Médicas de Córdoba.; Vol. 80 No. 2 (2023); 93-98 Revista de la Facultad de Ciencias Médicas de Córdoba; Vol. 80 Núm. 2 (2023); 93-98 Revista da Faculdade de Ciências Médicas de Córdoba; v. 80 n. 2 (2023); 93-98 1853-0605 0014-6722 10.31053/1853.0605.v80.n2 spa https://revistas.unc.edu.ar/index.php/med/article/view/37489/41756 https://revistas.unc.edu.ar/index.php/med/article/view/37489/42018 Derechos de autor 2023 Universidad Nacional de Córdoba http://creativecommons.org/licenses/by-nc/4.0 |