Células neuroendócrinas de la próstata
From the first description of Pretl in 1944, many authors have shown difterent morphological and immunohistochemical studies related to prostatic neuroendocrine cells. These cells belong to a neuroendocrine system, wide disseminated network, that is found in man)' human tissues. They secret neu...
| Autores principales: | , , |
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| Formato: | Artículo revista |
| Lenguaje: | Español |
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Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
2002
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| Materias: | |
| Acceso en línea: | https://revistas.unc.edu.ar/index.php/med/article/view/36848 |
| Aporte de: |
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I10-R327-article-36848 |
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| record_format |
ojs |
| institution |
Universidad Nacional de Córdoba |
| institution_str |
I-10 |
| repository_str |
R-327 |
| container_title_str |
Revista de la Facultad de Ciencias Médicas de Córdoba |
| language |
Español |
| format |
Artículo revista |
| topic |
Prostatic neuroendocríne cells Normal tissue Nodular hyperpiasia adenocarcinoma Morphological identification Silver impregnation technique Células neuroendocrinas prostáticas Tejido normal Hiperplasia nodular Adenocarcinoma Identificación morfológica Técnica de impregnación argéntica |
| spellingShingle |
Prostatic neuroendocríne cells Normal tissue Nodular hyperpiasia adenocarcinoma Morphological identification Silver impregnation technique Células neuroendocrinas prostáticas Tejido normal Hiperplasia nodular Adenocarcinoma Identificación morfológica Técnica de impregnación argéntica Herrero, Mónica Rodríguez , Adelaida Cejas , Hugo Células neuroendócrinas de la próstata |
| topic_facet |
Prostatic neuroendocríne cells Normal tissue Nodular hyperpiasia adenocarcinoma Morphological identification Silver impregnation technique Células neuroendocrinas prostáticas Tejido normal Hiperplasia nodular Adenocarcinoma Identificación morfológica Técnica de impregnación argéntica |
| author |
Herrero, Mónica Rodríguez , Adelaida Cejas , Hugo |
| author_facet |
Herrero, Mónica Rodríguez , Adelaida Cejas , Hugo |
| author_sort |
Herrero, Mónica |
| title |
Células neuroendócrinas de la próstata |
| title_short |
Células neuroendócrinas de la próstata |
| title_full |
Células neuroendócrinas de la próstata |
| title_fullStr |
Células neuroendócrinas de la próstata |
| title_full_unstemmed |
Células neuroendócrinas de la próstata |
| title_sort |
células neuroendócrinas de la próstata |
| description |
From the first description of Pretl in 1944, many authors have shown difterent morphological and immunohistochemical studies related to prostatic neuroendocrine cells. These cells belong to a neuroendocrine system, wide disseminated network, that is found in man)' human tissues. They secret neuroendocrine peptides and play an important role in the glandular pithelium regulation (growing, differentiation, and exocrine secretion), in both normal and hyperplastic glands. They are also present in ordinary prostatic adenocarcinoma and in unusual small ccli carcinoma. Recently, it has been suggested that prostatic neuroendocrine celis may be relatedto prognosis in prostatic carcinoma, particulary in cases with hormonal therapy resistant. In this study, there are 23 prostatic disorders: 11 nodular hyperpiasias and 12 adenocarcinomas, and also arcas of normal gland.The objetive is the morphologic identification of these cells with sil ver impregnation technique, in normal tissuc, nodular hyperplasia and adenocarcinorna. In normal gland and nodular hyperpiasia, the NE cells can he seen along most of the gland or near the urcthra, solitary or in small clusters. These cells are located hetween acinar epithelium cells and basement membrane, but they are a]so found within the stroma in relationto nerve endings. They characteristically contain argyrophil and argentaffin granules in the cytoplasm and exhibit cytoplasmatic processes extended to acinar or urethral lumen. Within the stroma, they are seen isolated with dendritic or ribbon-like cytoplasmaticprocesses. In this study, there is only one adenocarcinoma of high grade with NE cells. In this neoplasm they are increase in number, and appear isolated and more polymorphic |
| publisher |
Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología |
| publishDate |
2002 |
| url |
https://revistas.unc.edu.ar/index.php/med/article/view/36848 |
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AT herreromonica celulasneuroendocrinasdelaprostata AT rodriguezadelaida celulasneuroendocrinasdelaprostata AT cejashugo celulasneuroendocrinasdelaprostata |
| first_indexed |
2024-09-03T21:03:25Z |
| last_indexed |
2024-09-03T21:03:25Z |
| _version_ |
1809210310343524352 |
| spelling |
I10-R327-article-368482022-03-15T21:10:09Z Células neuroendócrinas de la próstata Herrero, Mónica Rodríguez , Adelaida Cejas , Hugo Prostatic neuroendocríne cells Normal tissue Nodular hyperpiasia adenocarcinoma Morphological identification Silver impregnation technique Células neuroendocrinas prostáticas Tejido normal Hiperplasia nodular Adenocarcinoma Identificación morfológica Técnica de impregnación argéntica From the first description of Pretl in 1944, many authors have shown difterent morphological and immunohistochemical studies related to prostatic neuroendocrine cells. These cells belong to a neuroendocrine system, wide disseminated network, that is found in man)' human tissues. They secret neuroendocrine peptides and play an important role in the glandular pithelium regulation (growing, differentiation, and exocrine secretion), in both normal and hyperplastic glands. They are also present in ordinary prostatic adenocarcinoma and in unusual small ccli carcinoma. Recently, it has been suggested that prostatic neuroendocrine celis may be relatedto prognosis in prostatic carcinoma, particulary in cases with hormonal therapy resistant. In this study, there are 23 prostatic disorders: 11 nodular hyperpiasias and 12 adenocarcinomas, and also arcas of normal gland.The objetive is the morphologic identification of these cells with sil ver impregnation technique, in normal tissuc, nodular hyperplasia and adenocarcinorna. In normal gland and nodular hyperpiasia, the NE cells can he seen along most of the gland or near the urcthra, solitary or in small clusters. These cells are located hetween acinar epithelium cells and basement membrane, but they are a]so found within the stroma in relationto nerve endings. They characteristically contain argyrophil and argentaffin granules in the cytoplasm and exhibit cytoplasmatic processes extended to acinar or urethral lumen. Within the stroma, they are seen isolated with dendritic or ribbon-like cytoplasmaticprocesses. In this study, there is only one adenocarcinoma of high grade with NE cells. In this neoplasm they are increase in number, and appear isolated and more polymorphic Desde la primera descripción de Pretl en 1944, muchos autores han realizado diferentes estudios morfológicos e inmunohistoquímicos sobre las células neuroendocrinas (NE) de la próstata.Estas células pertenecen a un sistema ncuroendocrino ampliamente diseminado en muchos tejidos humanos.Las células NE prostáticas segregan distintos péptidos neuroendocrinos con función reguladora sobre el epitelio glandular (crecimiento. diferenciación y secreción exocrina), tanto en la glándula normal corno en la hiperplásica. También están presentes en los adenocarcinomas convencionales y en el poco frecuente carcinoma de pequeñas células.Recientemente se ha postulado que las células NE prostáticas estarían relacionadas con el pronóstico del carcinoma prostático, especialmente en aquéllos resistentes a la terapia hormonal.En este estudio hay 23 patologías prostáticas: 11 hiperplasias nodulares y 12 adenocarcinomas. El estudio comprende además áreas glandulares normales, sin lesión. El objetivo es la identificación morfológica de éstas células con técnicas de impregnación argéntica en tejido normal, hiperpiásico y carcinornatoso.En la próstata normal y en la hiperpiasia nodular, estas células se encuentran en toda la glándula, en forma aislada o en pequeños grupos, y en las proximidades de la uretra. Se localizan entre las células epiteliales acinares y la membrana basa¡, y también en el estroma enrelación con terminaciones nerviosas. Poseen gránulos argi rófi los y argentafines en el citoplasma apical, y prolongaciones citoplasmáticas dirigidas hacia la luz acinar o uretral.En el estroma se presentan aisladas y con prolongaciones citoplasmáticas dendrílicas o acintadas. Están presentes en un solo adenocar-cinoma de alto grado, en el que son más numerosas y polimorfas, y se disponen en forma aislada Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2002-03-30 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion texto texto texto application/pdf https://revistas.unc.edu.ar/index.php/med/article/view/36848 10.31053/1853.0605.v59.n1.36848 Revista de la Facultad de Ciencias Médicas de Córdoba.; Vol. 59 No. 1 (2002); 91-96 Revista de la Facultad de Ciencias Médicas de Córdoba; Vol. 59 Núm. 1 (2002); 91-96 Revista da Faculdade de Ciências Médicas de Córdoba; v. 59 n. 1 (2002); 91-96 1853-0605 0014-6722 10.31053/1853.0605.v59.n1 spa https://revistas.unc.edu.ar/index.php/med/article/view/36848/37158 Derechos de autor 2022 Universidad Nacional de Córdoba http://creativecommons.org/licenses/by-nc/4.0 |