Mature teratoma of the filum terminale in an adult female. Report of a clinical case
Abstract: Mature teratomas are benign tumors, composed of tissues derived from at least two of the three germ lines: ectoderm, mesoderm, and endoderm. They are most frequently located in the gonads, sacrococcygeal area, mediastinum, and cranial fossa. In the spinal cord they represent only...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Artículo revista |
| Publicado: |
Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
2021
|
| Materias: | |
| Acceso en línea: | https://revistas.unc.edu.ar/index.php/med/article/view/35005 |
| Aporte de: |
| id |
I10-R327-article-35005 |
|---|---|
| record_format |
ojs |
| institution |
Universidad Nacional de Córdoba |
| institution_str |
I-10 |
| repository_str |
R-327 |
| container_title_str |
Revista de la Facultad de Ciencias Médicas de Córdoba |
| format |
Artículo revista |
| topic |
teratoma cauda equina spinal cord teratoma cauda equina médula espinal |
| spellingShingle |
teratoma cauda equina spinal cord teratoma cauda equina médula espinal Masciarelli , L Falco , F Pérez , C Aguado , G Ferraris , L Storniolo , A González , C Mature teratoma of the filum terminale in an adult female. Report of a clinical case |
| topic_facet |
teratoma cauda equina spinal cord teratoma cauda equina médula espinal |
| author |
Masciarelli , L Falco , F Pérez , C Aguado , G Ferraris , L Storniolo , A González , C |
| author_facet |
Masciarelli , L Falco , F Pérez , C Aguado , G Ferraris , L Storniolo , A González , C |
| author_sort |
Masciarelli , L |
| title |
Mature teratoma of the filum terminale in an adult female. Report of a clinical case |
| title_short |
Mature teratoma of the filum terminale in an adult female. Report of a clinical case |
| title_full |
Mature teratoma of the filum terminale in an adult female. Report of a clinical case |
| title_fullStr |
Mature teratoma of the filum terminale in an adult female. Report of a clinical case |
| title_full_unstemmed |
Mature teratoma of the filum terminale in an adult female. Report of a clinical case |
| title_sort |
mature teratoma of the filum terminale in an adult female. report of a clinical case |
| description |
Abstract:
Mature teratomas are benign tumors, composed of tissues derived from at least two of the three germ lines: ectoderm, mesoderm, and endoderm. They are most frequently located in the gonads, sacrococcygeal area, mediastinum, and cranial fossa. In the spinal cord they represent only 0.2-0.5% of all tumors, and within this location those in the thoracolumbar region are more frequent. Our objective is to report the case of a mature teratoma in the filum terminale, as this site of presentation is extremely infrequent.
We present the case of a 31-year-old patient, who consulted at Epidio Torres Hospital for a 5-year clinical picture of dysbasia, patchy hypoesthesia / paresthesia of the lower limbs, anesthesia in the genital region and sphincter incontinence. MRI showed a cystic lesion, 7 cm in maximum diameter in the spinal canal.
She was operated on, by the Neurosurgery team, carrying out an incomplete removal of the lesion, due to the interposition of nerve roots.
The tissues referred to Pathological Anatomy consisted of a fine capsule and a yellowish unctuous fragment, with hairy elements. Optical microscopy revealed that the capsule was lined by squamous mucosa, settling on fibroconnective, adipose and neural tissue with a mature appearance, with calcification foci. With these findings, the diagnosis of mature teratoma was reached.
The patient had to be re-operated on two occasions to undergo a surgical site toilet due to infection, and subsequently re-toilet with CSF fistula repair and placement of a spinal drain. She is currently hospitalized with antibiotic treatment, with good clinical evolution.
We conclude that mature spinal cord teratomas are not usually thought of as a differential diagnosis, since they are very rare in this location. Furthermore, despite being benign tumors, their surgical management with complete resection is very difficult to achieve, due to the complex anatomical location. |
| publisher |
Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología |
| publishDate |
2021 |
| url |
https://revistas.unc.edu.ar/index.php/med/article/view/35005 |
| work_keys_str_mv |
AT masciarellil matureteratomaofthefilumterminaleinanadultfemalereportofaclinicalcase AT falcof matureteratomaofthefilumterminaleinanadultfemalereportofaclinicalcase AT perezc matureteratomaofthefilumterminaleinanadultfemalereportofaclinicalcase AT aguadog matureteratomaofthefilumterminaleinanadultfemalereportofaclinicalcase AT ferrarisl matureteratomaofthefilumterminaleinanadultfemalereportofaclinicalcase AT stornioloa matureteratomaofthefilumterminaleinanadultfemalereportofaclinicalcase AT gonzalezc matureteratomaofthefilumterminaleinanadultfemalereportofaclinicalcase AT masciarellil teratomamadurodelfilumterminalenunamujeradultareportedeuncasoclinico AT falcof teratomamadurodelfilumterminalenunamujeradultareportedeuncasoclinico AT perezc teratomamadurodelfilumterminalenunamujeradultareportedeuncasoclinico AT aguadog teratomamadurodelfilumterminalenunamujeradultareportedeuncasoclinico AT ferrarisl teratomamadurodelfilumterminalenunamujeradultareportedeuncasoclinico AT stornioloa teratomamadurodelfilumterminalenunamujeradultareportedeuncasoclinico AT gonzalezc teratomamadurodelfilumterminalenunamujeradultareportedeuncasoclinico |
| first_indexed |
2024-09-03T21:02:55Z |
| last_indexed |
2024-09-03T21:02:55Z |
| _version_ |
1809210278469959680 |
| spelling |
I10-R327-article-350052024-04-15T16:19:09Z Mature teratoma of the filum terminale in an adult female. Report of a clinical case Teratoma maduro del filum terminal en una mujer adulta. Reporte de un caso clínico. Masciarelli , L Falco , F Pérez , C Aguado , G Ferraris , L Storniolo , A González , C teratoma cauda equina spinal cord teratoma cauda equina médula espinal Abstract: Mature teratomas are benign tumors, composed of tissues derived from at least two of the three germ lines: ectoderm, mesoderm, and endoderm. They are most frequently located in the gonads, sacrococcygeal area, mediastinum, and cranial fossa. In the spinal cord they represent only 0.2-0.5% of all tumors, and within this location those in the thoracolumbar region are more frequent. Our objective is to report the case of a mature teratoma in the filum terminale, as this site of presentation is extremely infrequent. We present the case of a 31-year-old patient, who consulted at Epidio Torres Hospital for a 5-year clinical picture of dysbasia, patchy hypoesthesia / paresthesia of the lower limbs, anesthesia in the genital region and sphincter incontinence. MRI showed a cystic lesion, 7 cm in maximum diameter in the spinal canal. She was operated on, by the Neurosurgery team, carrying out an incomplete removal of the lesion, due to the interposition of nerve roots. The tissues referred to Pathological Anatomy consisted of a fine capsule and a yellowish unctuous fragment, with hairy elements. Optical microscopy revealed that the capsule was lined by squamous mucosa, settling on fibroconnective, adipose and neural tissue with a mature appearance, with calcification foci. With these findings, the diagnosis of mature teratoma was reached. The patient had to be re-operated on two occasions to undergo a surgical site toilet due to infection, and subsequently re-toilet with CSF fistula repair and placement of a spinal drain. She is currently hospitalized with antibiotic treatment, with good clinical evolution. We conclude that mature spinal cord teratomas are not usually thought of as a differential diagnosis, since they are very rare in this location. Furthermore, despite being benign tumors, their surgical management with complete resection is very difficult to achieve, due to the complex anatomical location. Resumen: Los teratomas maduros son tumores benignos, compuestos por tejidos derivados de, al menos dos, de las tres líneas germinativas: ectodermo, mesodermo y endodermo. Se localizan con mayor frecuencia en las gónadas, área sacrococcígea, mediastino y fosa craneal. En la médula espinal representan solo el 0.2-0.5% de todos los tumores, y dentro de esta localización son más frecuentes los de la región toracolumbar. Nuestro objetivo es reportar el caso de un teratoma maduro en el filum terminal, por ser este lugar de presentación extremadamente infrecuente. Se presenta el caso de una paciente de 31 años, quien se presentó en el Hospital Epidio Torres por un cuadro clínico de disbasia de 5 años de evolución, hipoestesia/parestesia parcheada de miembros inferiores, anestesia en región genital e incontinencia de esfínteres. La RMN demostró una lesión quística, de 7 cm de diámetro máximo a nivel del canal raquídeo. Fue intervenida quirúrgicamente por el equipo de Neurocirugía, realizándose la extirpación incompleta de la lesión, debido a interposición de raíces nerviosas. Los tejidos remitidos a Anatomía Patológica estaban constituidos por una cápsula fina y un fragmento untuoso amarillento, con elementos pilosos. A la microscopía óptica, se evidenciaba que la cápsula estaba revestida por mucosa escamosa, asentando sobre tejido fibroconectivo, adiposo y neural de aspecto maduro, con focos de calcificación. Con estos hallazgos, se llegó al diagnóstico de teratoma maduro. La paciente debió ser re-intervenida en dos oportunidades para realizarse toilette del sitio quirúrgico por infección, y posteriormente re-toilette con reparación de fistula de LCR y colocación de drenaje espinal. Actualmente continúa internada con tratamiento antibiótico, con buena evolución clínica. Concluimos que los teratomas maduros de la médula espinal no suelen pensarse como diagnóstico diferencial, ya que son de muy rara presentación en esta localización. Además, a pesar de ser tumores benignos, su manejo quirúrgico con resección completa es muy dificultoso de lograr, debido a la compleja ubicación anatómica. Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2021-10-12 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion texto texto texto https://revistas.unc.edu.ar/index.php/med/article/view/35005 Revista de la Facultad de Ciencias Médicas de Córdoba.; Vol. 78 No. Suplemento (2021): Suplemento JIC XXII Revista de la Facultad de Ciencias Médicas de Córdoba; Vol. 78 Núm. Suplemento (2021): Suplemento JIC XXII Revista da Faculdade de Ciências Médicas de Córdoba; v. 78 n. Suplemento (2021): Suplemento JIC XXII 1853-0605 0014-6722 http://creativecommons.org/licenses/by-nc/4.0 |