Effect of the accumulation of risk factors on the risk of oral squamous cell carcinoma
Introduction: the causative factors of oral squamous cell carcinoma are not necessary and not sufficient causes, even the most accepted ones, such as tobacco and alcohol. Little is known about the cumulative effect of all risk factors for oral cancer. The objective of this work was to analyze whethe...
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| Formato: | Artículo revista |
| Lenguaje: | Español |
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Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
2021
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| Acceso en línea: | https://revistas.unc.edu.ar/index.php/med/article/view/31247 |
| Aporte de: |
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I10-R327-article-31247 |
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ojs |
| institution |
Universidad Nacional de Córdoba |
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I-10 |
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R-327 |
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Revista de la Facultad de Ciencias Médicas de Córdoba |
| language |
Español |
| format |
Artículo revista |
| topic |
mouth neoplasms squamous cell carcinoma risk factors causality neoplasias de la boca carcinoma de células escamosas factores de riesgo causalidad neoplasias bucais carcinoma de células escamosas fatores de risco causalidade |
| spellingShingle |
mouth neoplasms squamous cell carcinoma risk factors causality neoplasias de la boca carcinoma de células escamosas factores de riesgo causalidad neoplasias bucais carcinoma de células escamosas fatores de risco causalidade Piemonte, Eduardo David Lazos, Jerónimo Pablo Belardinelli, Paola Castillo, Graciela del Valle Talavera, Angel Daniel Secchi, Dante Gustavo Lanfranchi Tizeira, Héctor Eduardo Brunotto, Mabel Noemí Effect of the accumulation of risk factors on the risk of oral squamous cell carcinoma |
| topic_facet |
mouth neoplasms squamous cell carcinoma risk factors causality neoplasias de la boca carcinoma de células escamosas factores de riesgo causalidad neoplasias bucais carcinoma de células escamosas fatores de risco causalidade |
| author |
Piemonte, Eduardo David Lazos, Jerónimo Pablo Belardinelli, Paola Castillo, Graciela del Valle Talavera, Angel Daniel Secchi, Dante Gustavo Lanfranchi Tizeira, Héctor Eduardo Brunotto, Mabel Noemí |
| author_facet |
Piemonte, Eduardo David Lazos, Jerónimo Pablo Belardinelli, Paola Castillo, Graciela del Valle Talavera, Angel Daniel Secchi, Dante Gustavo Lanfranchi Tizeira, Héctor Eduardo Brunotto, Mabel Noemí |
| author_sort |
Piemonte, Eduardo David |
| title |
Effect of the accumulation of risk factors on the risk of oral squamous cell carcinoma |
| title_short |
Effect of the accumulation of risk factors on the risk of oral squamous cell carcinoma |
| title_full |
Effect of the accumulation of risk factors on the risk of oral squamous cell carcinoma |
| title_fullStr |
Effect of the accumulation of risk factors on the risk of oral squamous cell carcinoma |
| title_full_unstemmed |
Effect of the accumulation of risk factors on the risk of oral squamous cell carcinoma |
| title_sort |
effect of the accumulation of risk factors on the risk of oral squamous cell carcinoma |
| description |
Introduction: the causative factors of oral squamous cell carcinoma are not necessary and not sufficient causes, even the most accepted ones, such as tobacco and alcohol. Little is known about the cumulative effect of all risk factors for oral cancer. The objective of this work was to analyze whether the sum of oral cancer risk factors is associated with an increase in its risk.
Methods: a case-control study was carried out to determine the risk factors for oral cancer in the population under study, and then correlate the number of risk factors in each individual with the risk of oral cancer.
Results: the accumulation of oral cancer risk factors, analyzed using different strategies, was always associated with a significant increase in the risk of oral cancer. Having 3 or more risk factors was associated with an increased risk of oral cancer (OR 110, p <0.0001)
Conclusion: the main risk factor for oral cancer is the accumulation of its risk factors. The accumulation of risk factors could be considered a necessary cause for the development of oral cancer. |
| publisher |
Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología |
| publishDate |
2021 |
| url |
https://revistas.unc.edu.ar/index.php/med/article/view/31247 |
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I10-R327-article-312472021-12-29T20:15:49Z Effect of the accumulation of risk factors on the risk of oral squamous cell carcinoma Efecto de la acumulación de factores de riesgo en el riesgo de carcinoma de células escamosas bucal Efeito do acúmulo de fatores de risco sobre o risco de carcinoma epidermóide oral Piemonte, Eduardo David Lazos, Jerónimo Pablo Belardinelli, Paola Castillo, Graciela del Valle Talavera, Angel Daniel Secchi, Dante Gustavo Lanfranchi Tizeira, Héctor Eduardo Brunotto, Mabel Noemí mouth neoplasms squamous cell carcinoma risk factors causality neoplasias de la boca carcinoma de células escamosas factores de riesgo causalidad neoplasias bucais carcinoma de células escamosas fatores de risco causalidade Introduction: the causative factors of oral squamous cell carcinoma are not necessary and not sufficient causes, even the most accepted ones, such as tobacco and alcohol. Little is known about the cumulative effect of all risk factors for oral cancer. The objective of this work was to analyze whether the sum of oral cancer risk factors is associated with an increase in its risk. Methods: a case-control study was carried out to determine the risk factors for oral cancer in the population under study, and then correlate the number of risk factors in each individual with the risk of oral cancer. Results: the accumulation of oral cancer risk factors, analyzed using different strategies, was always associated with a significant increase in the risk of oral cancer. Having 3 or more risk factors was associated with an increased risk of oral cancer (OR 110, p <0.0001) Conclusion: the main risk factor for oral cancer is the accumulation of its risk factors. The accumulation of risk factors could be considered a necessary cause for the development of oral cancer. Introducción: los factores causales de carcinoma de células escamosas bucal son causas no necesarias y no suficientes, incluso los más aceptados, como tabaco y alcohol. Poco se conoce sobre el efecto acumulativo de todos los factores de riesgo de cáncer bucal. El objetivo de este trabajo fue analizar si la sumatoria de factores de riesgo de cáncer bucal se asocia con un aumento de su riesgo. Métodos: se realizó un estudio de casos y controles para determinar los factores de riesgo de cáncer bucal en la población bajo estudio, para luego correlacionar el número de factores de riesgo en cada individuo, con el riesgo de cáncer bucal. Resultados: la acumulación de factores de riesgo de cáncer bucal, analizada mediante diferentes estrategias, estuvo siempre asociada con un aumento significativo del riesgo de cáncer bucal. Tener 3 o más factores de riesgo estuvo asociado con mayor riesgo de cáncer bucal (OR 110, p<0,0001) Conclusión: el principal factor de riesgo de cáncer bucal es la acumulación de sus factores de riesgo. La acumulación de factores de riesgo podría considerarse una causa necesaria para el desarrollo de cáncer bucal. Introdução: os fatores causais do carcinoma epidermóide oral não são causas necessárias e nem suficientes, mesmo os mais aceitos, como o fumo e o álcool. Pouco se sabe sobre o efeito cumulativo de todos os fatores de risco para câncer oral. O objetivo deste trabalho foi analisar se a soma dos fatores de risco do câncer bucal está associada a um aumento do seu risco. Métodos: foi realizado um estudo caso-controle para determinar os fatores de risco para câncer bucal na população em estudo e, em seguida, correlacionar o número de fatores de risco em cada indivíduo com o risco de câncer bucal. Resultados: o acúmulo de fatores de risco para câncer bucal, analisados por meio de diferentes estratégias, sempre esteve associado a um aumento significativo no risco de câncer bucal. Ter 3 ou mais fatores de risco foi associado a um risco aumentado de câncer oral (OR 110, p <0,0001) Conclusão: o principal fator de risco para o câncer bucal é o acúmulo de seus fatores de risco. O acúmulo de fatores de risco pode ser considerado uma causa necessária para o desenvolvimento do câncer bucal. Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2021-06-28 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf text/html https://revistas.unc.edu.ar/index.php/med/article/view/31247 10.31053/1853.0605.v78.n2.31247 Revista de la Facultad de Ciencias Médicas de Córdoba.; Vol. 78 No. 2 (2021); 158-165 Revista de la Facultad de Ciencias Médicas de Córdoba; Vol. 78 Núm. 2 (2021); 158-165 Revista da Faculdade de Ciências Médicas de Córdoba; v. 78 n. 2 (2021); 158-165 1853-0605 0014-6722 10.31053/1853.0605.v78.n2 spa https://revistas.unc.edu.ar/index.php/med/article/view/31247/33808 https://revistas.unc.edu.ar/index.php/med/article/view/31247/33839 Derechos de autor 2021 Universidad Nacional de Córdoba http://creativecommons.org/licenses/by-nc/4.0 |