Clinical presentation of the first demyelinating event in pediatrics
Introduction: Isolated Clinical Syndrome (ACS) refers to the first clinical event with characteristics suggestive of multiple sclerosis (MS). Clinical case: We report the case of a previously healthy 8-year-old male patient hospitalized for altered gait with suspicion of transverse myelitis. Spinal...
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Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
2023
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| Acceso en línea: | https://revistas.unc.edu.ar/index.php/med/article/view/29664 |
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I10-R327-article-296642023-07-10T12:03:20Z Clinical presentation of the first demyelinating event in pediatrics Presentación clínica de primer evento desmielinizante en pediatría Apresentação clínica do primeiro evento desmielinizante em pediatria Sbruzzi, Agustina del Rosario Nasif, Salome Coloski, Macarena Pajariño, Santiago Gambarrutta, Fabian Franco, Paloma Jardi, Mailen Multiple Sclerosis Pediatrics Acute Transverse Myelitis in Demyelinating Disease of the Central Nervous System Esclerosis múltiple Pediatria Mielitis Transversa Aguda en Enfermedad Desmielinizante del Sistema Nervioso Central Esclerose Múltipla Pediatria Mielite Transversa Aguda na Doença Desmielinizante do Sistema Nervoso Central Introduction: Isolated Clinical Syndrome (ACS) refers to the first clinical event with characteristics suggestive of multiple sclerosis (MS). Clinical case: We report the case of a previously healthy 8-year-old male patient hospitalized for altered gait with suspicion of transverse myelitis. Spinal MRI was performed showing evidence of hyperintense D3-D5 lesion in T2. He receives treatment with intravenous corticosteroid therapy and with the result of oligoclonal bands in serum and CSF, a diagnosis of ACS is made. Conclusion: The objective is to describe a rare form of manifestation of demyelinating disease in pediatric age and to assess the importance of timely diagnosis and treatment. Introducción: El síndrome Clínico Aislado (SCA) hace referencia al primer evento clínico con características sugestivas de esclerosis múltiple (EM). Caso clínico: Se comunica el caso de un paciente masculino de 8 años previamente sano internado por alteración de la marcha con sospecha de mielitis transversa. Se realiza RMN medular donde se evidencia lesión en D3-D5 hiperintensa en T2. Recibe tratamiento con corticoterapia endovenosa y con resultado de bandas oligoclonales en suero y LCR se realiza diagnóstico de SCA. Conclusión: El objetivo es describir una forma poco frecuente de manifestación de enfermedad desmielinizante en la edad pediátrica y valorar la importancia del diagnóstico y tratamiento oportuno. Introdução: Síndrome Clínica Isolada (SCA) refere-se ao primeiro evento clínico com características sugestivas de esclerose múltipla (SM). Caso clínico: Relatamos o caso de um paciente do sexo masculino, com 8 anos de idade, previamente saudável, hospitalizado por marcha anormal com suspeita de mielite transversa. Foi realizada ressonância magnética da coluna vertebral, evidenciando lesão hiperintensa D3-D5 em T2. Ele recebe tratamento com corticoterapia endovenosa e, com o resultado de bandas oligoclonais no soro e no LCR, é feito um diagnóstico de SCA. Conclusão: O objetivo é descrever uma forma rara de manifestação da doença desmielinizante na idade pediátrica e avaliar a importância do diagnóstico e tratamento oportunos. Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2023-03-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion text/html application/pdf https://revistas.unc.edu.ar/index.php/med/article/view/29664 10.31053/1853.0605.v80.n1.29664 Revista de la Facultad de Ciencias Médicas de Córdoba.; Vol. 80 No. 1 (2023); 52-54 Revista de la Facultad de Ciencias Médicas de Córdoba; Vol. 80 Núm. 1 (2023); 52-54 Revista da Faculdade de Ciências Médicas de Córdoba; v. 80 n. 1 (2023); 52-54 1853-0605 0014-6722 10.31053/1853.0605.v80.n1 spa https://revistas.unc.edu.ar/index.php/med/article/view/29664/40885 https://revistas.unc.edu.ar/index.php/med/article/view/29664/40950 Derechos de autor 2023 Universidad Nacional de Córdoba http://creativecommons.org/licenses/by-nc/4.0 |
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Universidad Nacional de Córdoba |
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I-10 |
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R-327 |
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Revista de la Facultad de Ciencias Médicas de Córdoba |
| language |
Español |
| format |
Artículo revista |
| topic |
Multiple Sclerosis Pediatrics Acute Transverse Myelitis in Demyelinating Disease of the Central Nervous System Esclerosis múltiple Pediatria Mielitis Transversa Aguda en Enfermedad Desmielinizante del Sistema Nervioso Central Esclerose Múltipla Pediatria Mielite Transversa Aguda na Doença Desmielinizante do Sistema Nervoso Central |
| spellingShingle |
Multiple Sclerosis Pediatrics Acute Transverse Myelitis in Demyelinating Disease of the Central Nervous System Esclerosis múltiple Pediatria Mielitis Transversa Aguda en Enfermedad Desmielinizante del Sistema Nervioso Central Esclerose Múltipla Pediatria Mielite Transversa Aguda na Doença Desmielinizante do Sistema Nervoso Central Sbruzzi, Agustina del Rosario Nasif, Salome Coloski, Macarena Pajariño, Santiago Gambarrutta, Fabian Franco, Paloma Jardi, Mailen Clinical presentation of the first demyelinating event in pediatrics |
| topic_facet |
Multiple Sclerosis Pediatrics Acute Transverse Myelitis in Demyelinating Disease of the Central Nervous System Esclerosis múltiple Pediatria Mielitis Transversa Aguda en Enfermedad Desmielinizante del Sistema Nervioso Central Esclerose Múltipla Pediatria Mielite Transversa Aguda na Doença Desmielinizante do Sistema Nervoso Central |
| author |
Sbruzzi, Agustina del Rosario Nasif, Salome Coloski, Macarena Pajariño, Santiago Gambarrutta, Fabian Franco, Paloma Jardi, Mailen |
| author_facet |
Sbruzzi, Agustina del Rosario Nasif, Salome Coloski, Macarena Pajariño, Santiago Gambarrutta, Fabian Franco, Paloma Jardi, Mailen |
| author_sort |
Sbruzzi, Agustina del Rosario |
| title |
Clinical presentation of the first demyelinating event in pediatrics |
| title_short |
Clinical presentation of the first demyelinating event in pediatrics |
| title_full |
Clinical presentation of the first demyelinating event in pediatrics |
| title_fullStr |
Clinical presentation of the first demyelinating event in pediatrics |
| title_full_unstemmed |
Clinical presentation of the first demyelinating event in pediatrics |
| title_sort |
clinical presentation of the first demyelinating event in pediatrics |
| description |
Introduction: Isolated Clinical Syndrome (ACS) refers to the first clinical event with characteristics suggestive of multiple sclerosis (MS). Clinical case: We report the case of a previously healthy 8-year-old male patient hospitalized for altered gait with suspicion of transverse myelitis. Spinal MRI was performed showing evidence of hyperintense D3-D5 lesion in T2. He receives treatment with intravenous corticosteroid therapy and with the result of oligoclonal bands in serum and CSF, a diagnosis of ACS is made. Conclusion: The objective is to describe a rare form of manifestation of demyelinating disease in pediatric age and to assess the importance of timely diagnosis and treatment. |
| publisher |
Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología |
| publishDate |
2023 |
| url |
https://revistas.unc.edu.ar/index.php/med/article/view/29664 |
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