Cardiovascular disease and hormone therapy. Current status of the controversy

The cardiovascular effects of female sex steroids have many faces and are very complex.  To make this situation even more complicated different therapeutic regimens, types,  dosages or routes of administration may exhibit different effects of estrogens and  progestines in...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Siseles, Néstor, Gutiérrez, Pamela
Formato: Artículo revista
Lenguaje:Español
Publicado: Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2021
Materias:
.
Acceso en línea:https://revistas.unc.edu.ar/index.php/med/article/view/27919
Aporte de:
Revista de la Facultad de Ciencias Médicas de Córdoba de Universidad Nacional de Córdoba
id I10-R327-article-27919
record_format ojs
spelling I10-R327-article-279192024-08-27T18:27:49Z Cardiovascular disease and hormone therapy. Current status of the controversy Enfermedad cardiovascular terapia hormonal en reemplazo: estado actual de la controversia Siseles, Néstor Gutiérrez, Pamela . The cardiovascular effects of female sex steroids have many faces and are very complex.  To make this situation even more complicated different therapeutic regimens, types,  dosages or routes of administration may exhibit different effects of estrogens and  progestines in postmenopausal women. Furthermore, the interpretation of population  studies may be problematic by itself, in view of so many confounders and biases involved  and methodological flaws that sometimes are discovered only post-hoc. It seems therefore,  that in such a complicated situation making definite conclusions and guidelines is almost an  impossible task. Our suggestion to clinicians is to try and follow the main stream of clinical  data, looking at the general picture rather than the small details, and try to individualize therapy in order to maximize the benefits and minimize the adverse reactions and risks. This article discusses the current knowledge on hormone replacement therapy and the  cardiovascular system. It is not an overview since data are vast, but in the post-WHl era this  chapter presents current ideas and trends in this field to be used by people who practice  menopause medicine for their own clinical decisions Los efectos cardiovasculares de los esteroides sexuales en la mujer son complejos y para  complicar aún más la situación existen diferencias en los efectos de los distintos regímenes  terapéuticos, dosis y vías de administración de la terapia hormonal de reemplazo (THR) en la post-menopausia. Incluso la interpretación de los estudios clínicos es problemática en  vista de múltiples factores que pueden llevar a confusión, además de los sesgos y defectos  metodológicos encontrados en algunas circunstancias post-hoc. En este contexto plantear conclusiones definitivas y recomendaciones parecería una tarea imposible. Nuestra  sugerencia para la práctica clínica diaria es intentar seguir la corriente principal de la  información científica, analizar los datos generales e intentar individualizar la THR para maximizar los beneficios y minimizar los efectos adversos. Este artículo resume el estado  actual de la THR y el sistema cardiovascular. Dado lo vasto de la información en la era postWHl, solo presentamos las ideas actuales y tendencias en este campo para el uso  práctico del profesional en sus decisiones clínicas. Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2021-03-25 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://revistas.unc.edu.ar/index.php/med/article/view/27919 10.31053/1853.0605.v62.n2.27919 Revista de la Facultad de Ciencias Médicas de Córdoba.; Vol. 62 No. 2 (2005); 67 - 71 Revista de la Facultad de Ciencias Médicas de Córdoba; Vol. 62 Núm. 2 (2005); 67 - 71 Revista da Faculdade de Ciências Médicas de Córdoba; v. 62 n. 2 (2005); 67 - 71 1853-0605 0014-6722 spa https://revistas.unc.edu.ar/index.php/med/article/view/27919/29193 Derechos de autor 2021 Universidad Nacional de Córdoba https://creativecommons.org/licenses/by-nc/4.0
institution Universidad Nacional de Córdoba
institution_str I-10
repository_str R-327
container_title_str Revista de la Facultad de Ciencias Médicas de Córdoba
language Español
format Artículo revista
topic .
spellingShingle .
Siseles, Néstor
Gutiérrez, Pamela
Cardiovascular disease and hormone therapy. Current status of the controversy
topic_facet .
author Siseles, Néstor
Gutiérrez, Pamela
author_facet Siseles, Néstor
Gutiérrez, Pamela
author_sort Siseles, Néstor
title Cardiovascular disease and hormone therapy. Current status of the controversy
title_short Cardiovascular disease and hormone therapy. Current status of the controversy
title_full Cardiovascular disease and hormone therapy. Current status of the controversy
title_fullStr Cardiovascular disease and hormone therapy. Current status of the controversy
title_full_unstemmed Cardiovascular disease and hormone therapy. Current status of the controversy
title_sort cardiovascular disease and hormone therapy. current status of the controversy
description The cardiovascular effects of female sex steroids have many faces and are very complex.  To make this situation even more complicated different therapeutic regimens, types,  dosages or routes of administration may exhibit different effects of estrogens and  progestines in postmenopausal women. Furthermore, the interpretation of population  studies may be problematic by itself, in view of so many confounders and biases involved  and methodological flaws that sometimes are discovered only post-hoc. It seems therefore,  that in such a complicated situation making definite conclusions and guidelines is almost an  impossible task. Our suggestion to clinicians is to try and follow the main stream of clinical  data, looking at the general picture rather than the small details, and try to individualize therapy in order to maximize the benefits and minimize the adverse reactions and risks. This article discusses the current knowledge on hormone replacement therapy and the  cardiovascular system. It is not an overview since data are vast, but in the post-WHl era this  chapter presents current ideas and trends in this field to be used by people who practice  menopause medicine for their own clinical decisions
publisher Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
publishDate 2021
url https://revistas.unc.edu.ar/index.php/med/article/view/27919
work_keys_str_mv AT siselesnestor cardiovasculardiseaseandhormonetherapycurrentstatusofthecontroversy
AT gutierrezpamela cardiovasculardiseaseandhormonetherapycurrentstatusofthecontroversy
AT siselesnestor enfermedadcardiovascularterapiahormonalenreemplazoestadoactualdelacontroversia
AT gutierrezpamela enfermedadcardiovascularterapiahormonalenreemplazoestadoactualdelacontroversia
first_indexed 2024-09-03T21:01:48Z
last_indexed 2024-09-03T21:01:48Z
_version_ 1809210207787548672

Ejemplares similares