Intracranial lipomatous hamartoma (lipoma). Presentation of two cases.

Intracranial lipomas are very rare, probably congenital lesions. Although they can occur in any part of the intracranial space, a good proportion of cases tend to be located around the midline or adjacent areas especially the corpus callosum (50%) followed in order of frequency by the quadrigra...

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Autores principales: Salas, T, Perez, C, Storniolo, A, Aguado, G, Ferraris, L, Gonzales, C, Ferraris, R
Formato: Artículo revista
Lenguaje:Español
Publicado: Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2019
Materias:
neurology
cerebellum
hamartoma
benign
lipoma
neurologia
cerebelo
benigno
Acceso en línea:https://revistas.unc.edu.ar/index.php/med/article/view/25860
Aporte de:
Revista de la Facultad de Ciencias Médicas de Córdoba de Universidad Nacional de Córdoba
id I10-R327-article-25860
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institution Universidad Nacional de Córdoba
institution_str I-10
repository_str R-327
container_title_str Revista de la Facultad de Ciencias Médicas de Córdoba
language Español
format Artículo revista
topic neurology
cerebellum
hamartoma
benign
lipoma
neurologia
cerebelo
hamartoma
benigno
lipoma
spellingShingle neurology
cerebellum
hamartoma
benign
lipoma
neurologia
cerebelo
hamartoma
benigno
lipoma
Salas, T
Perez, C
Storniolo, A
Aguado, G
Ferraris, L
Gonzales, C
Ferraris, R
Intracranial lipomatous hamartoma (lipoma). Presentation of two cases.
topic_facet neurology
cerebellum
hamartoma
benign
lipoma
neurologia
cerebelo
hamartoma
benigno
lipoma
author Salas, T
Perez, C
Storniolo, A
Aguado, G
Ferraris, L
Gonzales, C
Ferraris, R
author_facet Salas, T
Perez, C
Storniolo, A
Aguado, G
Ferraris, L
Gonzales, C
Ferraris, R
author_sort Salas, T
title Intracranial lipomatous hamartoma (lipoma). Presentation of two cases.
title_short Intracranial lipomatous hamartoma (lipoma). Presentation of two cases.
title_full Intracranial lipomatous hamartoma (lipoma). Presentation of two cases.
title_fullStr Intracranial lipomatous hamartoma (lipoma). Presentation of two cases.
title_full_unstemmed Intracranial lipomatous hamartoma (lipoma). Presentation of two cases.
title_sort intracranial lipomatous hamartoma (lipoma). presentation of two cases.
description Intracranial lipomas are very rare, probably congenital lesions. Although they can occur in any part of the intracranial space, a good proportion of cases tend to be located around the midline or adjacent areas especially the corpus callosum (50%) followed in order of frequency by the quadrigramine lamina, other reported locations include the vermis cerebellar and the pontocerebellar angle. There are two cases of lipomatous hamartoma, diagnosed in our center, in the last 10 years, of a total of 788 brain biopsies performed. Case 1: 56-year-old woman consulted for vertiginous syndrome of months of evolution, so a brain tomography was performed, which showed a solid, heterogeneous nodular image measuring 22 mm, located in the cerebellum. The neurosurgery department decided to surgical intervention of the lesion with biopsy for intraoperative study, which after its evaluation was reported as negative for malignancy with definitive diagnosis by deferred study. With the reported result, the total removal of the lesion was decided. In the average macroscopic examination 23x18x15 mm., It was nodular, solid well delimited, to the yellowish cut with whitish areas. In the histological study, in addition to the predominant component of adipose tissue, blood vessels were observed with marked wall thickening, nerve fillets and fibroconnective tissue. Case 2: A 62-year-old woman consulted due to severe headache, for which reason she underwent a cerebral tomography that showed a heterogeneous tumor lesion of 18 mm, located in the quadrigeminal lamina. A lumpectomy was performed and sent to our center. Macroscopically the lesion was nodular, solid white-yellowish. Microscopically it showed adipose tissue tracts of fibroconnective tissue and congestive vessels. Lipomas used to be reported primarily as incidental findings at autopsy. Advances in neuroimaging techniques have greatly improved the possibility of being discovered during life.
publisher Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
publishDate 2019
url https://revistas.unc.edu.ar/index.php/med/article/view/25860
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first_indexed 2024-09-03T21:01:11Z
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spelling I10-R327-article-258602024-08-27T18:26:29Z Intracranial lipomatous hamartoma (lipoma). Presentation of two cases. Hamartoma lipomatoso (lipoma) intracraneal. Presentación de dos casos. Salas, T Perez, C Storniolo, A Aguado, G Ferraris, L Gonzales, C Ferraris, R neurology cerebellum hamartoma benign lipoma neurologia cerebelo hamartoma benigno lipoma Intracranial lipomas are very rare, probably congenital lesions. Although they can occur in any part of the intracranial space, a good proportion of cases tend to be located around the midline or adjacent areas especially the corpus callosum (50%) followed in order of frequency by the quadrigramine lamina, other reported locations include the vermis cerebellar and the pontocerebellar angle. There are two cases of lipomatous hamartoma, diagnosed in our center, in the last 10 years, of a total of 788 brain biopsies performed. Case 1: 56-year-old woman consulted for vertiginous syndrome of months of evolution, so a brain tomography was performed, which showed a solid, heterogeneous nodular image measuring 22 mm, located in the cerebellum. The neurosurgery department decided to surgical intervention of the lesion with biopsy for intraoperative study, which after its evaluation was reported as negative for malignancy with definitive diagnosis by deferred study. With the reported result, the total removal of the lesion was decided. In the average macroscopic examination 23x18x15 mm., It was nodular, solid well delimited, to the yellowish cut with whitish areas. In the histological study, in addition to the predominant component of adipose tissue, blood vessels were observed with marked wall thickening, nerve fillets and fibroconnective tissue. Case 2: A 62-year-old woman consulted due to severe headache, for which reason she underwent a cerebral tomography that showed a heterogeneous tumor lesion of 18 mm, located in the quadrigeminal lamina. A lumpectomy was performed and sent to our center. Macroscopically the lesion was nodular, solid white-yellowish. Microscopically it showed adipose tissue tracts of fibroconnective tissue and congestive vessels. Lipomas used to be reported primarily as incidental findings at autopsy. Advances in neuroimaging techniques have greatly improved the possibility of being discovered during life. Los lipomas intracraneales son muy raros, probablemente lesiones congénitas. Aunque pueden ocurrir en cualquier parte del espacio intracraneal, una buena proporción de los casos tienden a ubicarse alrededor de la línea media o áreas adyacentes especialmente el cuerpo calloso (50 %) seguido en orden de frecuencia la lámina cuadrigémina, otras localizaciones reportadas incluyen el vermis cerebeloso y el ángulo pontocerebeloso.  Se presentan dos casos de hamartoma lipomatoso, diagnosticados en nuestro centro, en los últimos 10 años, de un total de 788 biopsias cerebrales realizadas. Caso 1: Mujer de 56 años consultó por síndrome vertiginoso de meses de evolución por lo que se realizó  tomografía de cerebro, que evidenció una imagen nodular sólida,heterogénea que medía 22 mm, localizado en cerebelo. El servicio de neurocirugía decidió intervención quirúrgica de la lesión con toma biopsia para estudio intraoperatorio, que después de su evaluación se informó como negativo para malignidad con diagnóstico definitivo por estudio diferido. Con el resultado informado se decidió la extirpación total de la lesión. En el examen  macroscopico media 23x18x15 mm., era nodular, sólida bien delimitada, al corte de color amarillento con áreas blanquecinas. En el estudio histológico además del componente predominante de tejido adiposo se observaron vasos sanguíneos con marcado engrosamiento de la pared,filetes nerviosos y tejido fibroconectivo. Caso 2: Mujer de 62 años consultó por cefalea intensa, por lo que se le realizó tomografía cerebral que mostro lesión tumoral heterogénea de 18 mm., localizada en la lámina cuadrigémina. Se realizó tumorectomía y se remitió a nuestro centro. Macroscópicamente la lesión era nodular, solida de color blanco-amarillenta. Microscopicamente mostro tejido adiposo tractos de tejido fibroconectivo y vasos congestivos. Los lipomas solían ser reportados principalmente como hallazgos incidentales en la autopsia. Los avances en las técnicas de neuroimagen han mejorado enormemente la posibilidad de ser descubiertos durante la vida.  Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2019-10-21 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://revistas.unc.edu.ar/index.php/med/article/view/25860 Revista de la Facultad de Ciencias Médicas de Córdoba.; 2019: Suplemento JIC XX Revista de la Facultad de Ciencias Médicas de Córdoba; 2019: Suplemento JIC XX Revista da Faculdade de Ciências Médicas de Córdoba; 2019: Suplemento JIC XX 1853-0605 0014-6722 10.31053/1853.0605.v76.nSuplemento spa https://revistas.unc.edu.ar/index.php/med/article/view/25860/27687 Derechos de autor 2019 Universidad Nacional de Córdoba https://creativecommons.org/licenses/by-nc/4.0

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