Presentation of 30 cases of recurrent retinochoroiditis
Ocular toxoplasmosis is a pathology that usually presents with non-evolving retinochoroidal lesions; however reactivations or recurrences are possible due to immunosuppressive diseases such as AIDS, neoplasms, drug treatments, due to hormonal factors typical of puberty, associated with pregnancy and...
| Autores principales: | , , , , , |
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| Formato: | Artículo revista |
| Lenguaje: | Español |
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Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
2019
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| Materias: | |
| Acceso en línea: | https://revistas.unc.edu.ar/index.php/med/article/view/25708 |
| Aporte de: |
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I10-R327-article-25708 |
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| institution |
Universidad Nacional de Córdoba |
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I-10 |
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R-327 |
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Revista de la Facultad de Ciencias Médicas de Córdoba |
| language |
Español |
| format |
Artículo revista |
| topic |
retinochoroiditis recurrences toxoplasmosis retinocoroiditis recidivas toxoplasmosis |
| spellingShingle |
retinochoroiditis recurrences toxoplasmosis retinocoroiditis recidivas toxoplasmosis Maffrand , R Maffrand, C Tomas, A Paez Rearte, M Pizzi, RD Pizzi, HL Presentation of 30 cases of recurrent retinochoroiditis |
| topic_facet |
retinochoroiditis recurrences toxoplasmosis retinocoroiditis recidivas toxoplasmosis |
| author |
Maffrand , R Maffrand, C Tomas, A Paez Rearte, M Pizzi, RD Pizzi, HL |
| author_facet |
Maffrand , R Maffrand, C Tomas, A Paez Rearte, M Pizzi, RD Pizzi, HL |
| author_sort |
Maffrand , R |
| title |
Presentation of 30 cases of recurrent retinochoroiditis |
| title_short |
Presentation of 30 cases of recurrent retinochoroiditis |
| title_full |
Presentation of 30 cases of recurrent retinochoroiditis |
| title_fullStr |
Presentation of 30 cases of recurrent retinochoroiditis |
| title_full_unstemmed |
Presentation of 30 cases of recurrent retinochoroiditis |
| title_sort |
presentation of 30 cases of recurrent retinochoroiditis |
| description |
Ocular toxoplasmosis is a pathology that usually presents with non-evolving retinochoroidal lesions; however reactivations or recurrences are possible due to immunosuppressive diseases such as AIDS, neoplasms, drug treatments, due to hormonal factors typical of puberty, associated with pregnancy and even for unknown reasons. Toxoplasma gondii is an intracellular cosmopolitan parasite that affects numerous hosts and in its evolutionary cycle leaves cysts that remain viable, in tissues such as the brain and the retina, which can be reactivated; the reproduction of Toxoplasma initiates a new cycle of eye injuries with serious compromise that can lead to loss of vision.
The objective of the presentation was to report on 30 cases of reactivated retinochoroiditis and their causal relationship.
Presentation of cases: 30 reactivated retinochoroiditis are reported from patients attending the Ophthalmology Service of the Pediatric Hospital of the Child Jesus of the city of Córdoba, Argentina. They were studied through ophthalmological procedures of direct and indirect ophthalmoscopy, fundus biomicroscopy, retinography (RG), retinofluoresceinography (RFG) and by the use of immunological methods; which gave positive results in all cases. The reactivations were related to pregnancy in 1 case, with puberty in 13 cases, with the administration of corticosteroid therapy in 6 cases, with other intercurrent diseases in 7 cases and not attributable to known causes in 3 cases.
Reactivations of toxoplasmosis retinochoroiditis are linked to diseases that cause immunosuppression such as AIDS, corticosteroid treatments, cytostatics, neoplasms. Pregnancy and puberty may be associated with recurrences. A particular situation usually occurs at puberty, in young people without prior diagnosis of toxoplasmosis, or ocular symptoms, but carriers of congenital toxoplasmosis with a reactivation of latent parasitic cysts in the retina leading to complex ocular patology. Therefore, an efficient monitoring of the pregnant woman must be carried out through the methods available for the early diagnosis of congenital toxoplasmosis. Patients with toxoplasmic retinochoroiditis have to receive regular ophthalmological controls due to the possibility of recurrence, in order to receive timely treatment that limits the magnitude of eye damage |
| publisher |
Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología |
| publishDate |
2019 |
| url |
https://revistas.unc.edu.ar/index.php/med/article/view/25708 |
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I10-R327-article-257082024-08-27T18:26:06Z Presentation of 30 cases of recurrent retinochoroiditis Presentación de 30 casos de retinocoroiditis recidivante. Maffrand , R Maffrand, C Tomas, A Paez Rearte, M Pizzi, RD Pizzi, HL retinochoroiditis recurrences toxoplasmosis retinocoroiditis recidivas toxoplasmosis Ocular toxoplasmosis is a pathology that usually presents with non-evolving retinochoroidal lesions; however reactivations or recurrences are possible due to immunosuppressive diseases such as AIDS, neoplasms, drug treatments, due to hormonal factors typical of puberty, associated with pregnancy and even for unknown reasons. Toxoplasma gondii is an intracellular cosmopolitan parasite that affects numerous hosts and in its evolutionary cycle leaves cysts that remain viable, in tissues such as the brain and the retina, which can be reactivated; the reproduction of Toxoplasma initiates a new cycle of eye injuries with serious compromise that can lead to loss of vision. The objective of the presentation was to report on 30 cases of reactivated retinochoroiditis and their causal relationship. Presentation of cases: 30 reactivated retinochoroiditis are reported from patients attending the Ophthalmology Service of the Pediatric Hospital of the Child Jesus of the city of Córdoba, Argentina. They were studied through ophthalmological procedures of direct and indirect ophthalmoscopy, fundus biomicroscopy, retinography (RG), retinofluoresceinography (RFG) and by the use of immunological methods; which gave positive results in all cases. The reactivations were related to pregnancy in 1 case, with puberty in 13 cases, with the administration of corticosteroid therapy in 6 cases, with other intercurrent diseases in 7 cases and not attributable to known causes in 3 cases. Reactivations of toxoplasmosis retinochoroiditis are linked to diseases that cause immunosuppression such as AIDS, corticosteroid treatments, cytostatics, neoplasms. Pregnancy and puberty may be associated with recurrences. A particular situation usually occurs at puberty, in young people without prior diagnosis of toxoplasmosis, or ocular symptoms, but carriers of congenital toxoplasmosis with a reactivation of latent parasitic cysts in the retina leading to complex ocular patology. Therefore, an efficient monitoring of the pregnant woman must be carried out through the methods available for the early diagnosis of congenital toxoplasmosis. Patients with toxoplasmic retinochoroiditis have to receive regular ophthalmological controls due to the possibility of recurrence, in order to receive timely treatment that limits the magnitude of eye damage La toxoplasmosis ocular es una patología que por lo general, se presenta con lesiones retinocoroideas no evolutivas, no obstante son posibles las reactivaciones o recidivas debido a enfermedades inmunodepresoras como SIDA, neoplasias, tratamientos medicamentosos, por factores hormonales propios de la pubertad, asociado al embarazo e incluso por causas desconocidas. El Toxoplasma gondii es un parásito cosmopolita intracelular que afecta a numerosos hospedadores y en su ciclo evolutivo deja quistes que permanecen viables, en tejidos como el cerebro y la retina, los que pueden reactivarse; la reproducción del Toxoplasma inicia un nuevo ciclo de lesiones oculares con compromiso grave que puede conducir a la pérdida de la visión. El objetivo de la presentación fue informar sobre 30 casos de retinocoroiditis reactivadas y su relación causal. Presentación de los casos: Se informan 30 retinocoroiditis reactivadas de pacientes concurrentes al Servicio de Oftalmología del Hospital Pediátrico del Niño Jesús de la ciudad de Córdoba, Argentina. Se estudiaron a través de oftalmoscopía directa e indirecta, biomicroscopía del Fondo, retinografía (RG), retinofluoresceinografía (RFG) y mediante el empleo de métodos inmunológicos; los cuales dieron resultados positivos en todos los casos. Las reactivaciones se relacionaron con el embarazo en 1 caso, con la pubertad en 13 casos, con la administración de corticoterapia en 6 casos, con otras enfermedades intercurrentes en 7 casos y no atribuibles a causas conocidas en 3 casos. Las reactivaciones de retinocoroiditis por toxoplasmosis están ligadas a enfermedades que causan inmunodepresión, a el embarazo y la pubertad. En ocasiones, en jóvenes sin diagnóstico previo de toxoplasmosis, ni clínica ocular, pero portadores de una toxoplasmosis congénita se da una reactivación de los quistes parasitarios latentes en retina, con la producción de complejos cuadros oculares. Por lo dicho, se debe realizar un eficiente seguimiento de la embarazada a través de los métodos disponibles para el diagnóstico precoz de la toxoplasmosis congénita. Los pacientes portadores de retinocoroiditis por toxoplasmosis tienen que recibir controles oftalmológicos periódicos, debido a la posibilidad de las recidivas, a los fines de recibir tratamiento oportuno que limite la magnitud del daño ocular Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2019-10-10 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://revistas.unc.edu.ar/index.php/med/article/view/25708 Revista de la Facultad de Ciencias Médicas de Córdoba.; 2019: Suplemento JIC XX Revista de la Facultad de Ciencias Médicas de Córdoba; 2019: Suplemento JIC XX Revista da Faculdade de Ciências Médicas de Córdoba; 2019: Suplemento JIC XX 1853-0605 0014-6722 10.31053/1853.0605.v76.nSuplemento spa https://revistas.unc.edu.ar/index.php/med/article/view/25708/27403 Derechos de autor 2019 Universidad Nacional de Córdoba https://creativecommons.org/licenses/by-nc/4.0 |