Think of Leishmaniasis, even in non-endemic areas. Presentation of two cases
Leishmaniasis are a group of diseases caused by infection with protozoa of the genus Leishmania, which parasitize the cells of the reticuloendothelial system. It is transmitted by the bite of female mosquitoes of the genera Phlebotomus and Lutzomya, whose reservoi...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Artículo revista |
| Lenguaje: | Español |
| Publicado: |
Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
2019
|
| Materias: | |
| Acceso en línea: | https://revistas.unc.edu.ar/index.php/med/article/view/25616 |
| Aporte de: |
| id |
I10-R327-article-25616 |
|---|---|
| record_format |
ojs |
| institution |
Universidad Nacional de Córdoba |
| institution_str |
I-10 |
| repository_str |
R-327 |
| container_title_str |
Revista de la Facultad de Ciencias Médicas de Córdoba |
| language |
Español |
| format |
Artículo revista |
| topic |
skin leishmania infection piel leishmania infección |
| spellingShingle |
skin leishmania infection piel leishmania infección Meza Vetanzo , Z Martinez, M Rodriguez, N Pets, H Volmaro, K Suaréz Ghibaudo, H Mandrile, J Herrero, MV Think of Leishmaniasis, even in non-endemic areas. Presentation of two cases |
| topic_facet |
skin leishmania infection piel leishmania infección |
| author |
Meza Vetanzo , Z Martinez, M Rodriguez, N Pets, H Volmaro, K Suaréz Ghibaudo, H Mandrile, J Herrero, MV |
| author_facet |
Meza Vetanzo , Z Martinez, M Rodriguez, N Pets, H Volmaro, K Suaréz Ghibaudo, H Mandrile, J Herrero, MV |
| author_sort |
Meza Vetanzo , Z |
| title |
Think of Leishmaniasis, even in non-endemic areas. Presentation of two cases |
| title_short |
Think of Leishmaniasis, even in non-endemic areas. Presentation of two cases |
| title_full |
Think of Leishmaniasis, even in non-endemic areas. Presentation of two cases |
| title_fullStr |
Think of Leishmaniasis, even in non-endemic areas. Presentation of two cases |
| title_full_unstemmed |
Think of Leishmaniasis, even in non-endemic areas. Presentation of two cases |
| title_sort |
think of leishmaniasis, even in non-endemic areas. presentation of two cases |
| description |
Leishmaniasis are a group of diseases caused by infection with protozoa of the genus Leishmania, which parasitize the cells of the reticuloendothelial system. It is transmitted by the bite of female mosquitoes of the genera Phlebotomus and Lutzomya, whose reservoir are vertebrate animals. The disease is widely distributed in America and is endemic in the northern provinces of our country, where the agent involved is L. brazilensis. In America and Argentina there are three clinical forms: visceral (LV), cutaneous (LC) and mucocutaneous (LMC). Due to global warming, population migration and deforestation, the epidemiological border line has advanced towards our province, which forces us to keep this pathology in mind. The objective of the present work was to communicate two cases, uncommon in our environment, highlighting the importance of clinical-pathological correlation and morphological changes, sometimes subtle, which are observed in the biopsy. Its main importance is the early diagnosis and timely treatment, which prevents the progress of the lesions.
The first case is a 52 years old man, carpenter, native of the capital city of Córdoba. He had an erythematous plaque on the left cheek of two months of evolution, which began, after a trip to Jujuy, as an asymptomatic erythematous papule with progressive enlargement; currently covered with serohematic scabs, it measured 3-4cm in diameter and was surrounded by erythematous-edematous halo slightly indurated on palpation. The second case is a 76-year-old man, a native of the Punilla Valley, who consulted for a deep papular lesion in the calf, asymptomatic of 2 months of evolution after a trip to Brazil. In both cases, biopsies were obtained, fixed in 10% formalin, included in paraffin blocks and colored with hematoxylin / eosin, Giemsa, PAS and Ziehl Neelsen (ZN). In the histological sections were observed a dense inflammatory infiltrate, with plasma-histio-lymphocyte, visualizing the parasitic forms of extra and intracellular amastigostes.
Two cases of cutaneous leishmaniasis are reported, a rare condition in our environment, highlighting the importance of epidemiological antecedents to the correct diagnosis and timely treatment. |
| publisher |
Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología |
| publishDate |
2019 |
| url |
https://revistas.unc.edu.ar/index.php/med/article/view/25616 |
| work_keys_str_mv |
AT mezavetanzoz thinkofleishmaniasiseveninnonendemicareaspresentationoftwocases AT martinezm thinkofleishmaniasiseveninnonendemicareaspresentationoftwocases AT rodriguezn thinkofleishmaniasiseveninnonendemicareaspresentationoftwocases AT petsh thinkofleishmaniasiseveninnonendemicareaspresentationoftwocases AT volmarok thinkofleishmaniasiseveninnonendemicareaspresentationoftwocases AT suarezghibaudoh thinkofleishmaniasiseveninnonendemicareaspresentationoftwocases AT mandrilej thinkofleishmaniasiseveninnonendemicareaspresentationoftwocases AT herreromv thinkofleishmaniasiseveninnonendemicareaspresentationoftwocases AT mezavetanzoz pensarenleishmaniasisaunenzonasnoendemicaspresentaciondedoscasos AT martinezm pensarenleishmaniasisaunenzonasnoendemicaspresentaciondedoscasos AT rodriguezn pensarenleishmaniasisaunenzonasnoendemicaspresentaciondedoscasos AT petsh pensarenleishmaniasisaunenzonasnoendemicaspresentaciondedoscasos AT volmarok pensarenleishmaniasisaunenzonasnoendemicaspresentaciondedoscasos AT suarezghibaudoh pensarenleishmaniasisaunenzonasnoendemicaspresentaciondedoscasos AT mandrilej pensarenleishmaniasisaunenzonasnoendemicaspresentaciondedoscasos AT herreromv pensarenleishmaniasisaunenzonasnoendemicaspresentaciondedoscasos |
| first_indexed |
2024-09-03T21:00:48Z |
| last_indexed |
2024-09-03T21:00:48Z |
| _version_ |
1809210145530445824 |
| spelling |
I10-R327-article-256162024-08-27T18:25:57Z Think of Leishmaniasis, even in non-endemic areas. Presentation of two cases Pensar en Leishmaniasis, aún en zonas no endémicas. Presentación de dos casos Meza Vetanzo , Z Martinez, M Rodriguez, N Pets, H Volmaro, K Suaréz Ghibaudo, H Mandrile, J Herrero, MV skin leishmania infection piel leishmania infección Leishmaniasis are a group of diseases caused by infection with protozoa of the genus Leishmania, which parasitize the cells of the reticuloendothelial system. It is transmitted by the bite of female mosquitoes of the genera Phlebotomus and Lutzomya, whose reservoir are vertebrate animals. The disease is widely distributed in America and is endemic in the northern provinces of our country, where the agent involved is L. brazilensis. In America and Argentina there are three clinical forms: visceral (LV), cutaneous (LC) and mucocutaneous (LMC). Due to global warming, population migration and deforestation, the epidemiological border line has advanced towards our province, which forces us to keep this pathology in mind. The objective of the present work was to communicate two cases, uncommon in our environment, highlighting the importance of clinical-pathological correlation and morphological changes, sometimes subtle, which are observed in the biopsy. Its main importance is the early diagnosis and timely treatment, which prevents the progress of the lesions. The first case is a 52 years old man, carpenter, native of the capital city of Córdoba. He had an erythematous plaque on the left cheek of two months of evolution, which began, after a trip to Jujuy, as an asymptomatic erythematous papule with progressive enlargement; currently covered with serohematic scabs, it measured 3-4cm in diameter and was surrounded by erythematous-edematous halo slightly indurated on palpation. The second case is a 76-year-old man, a native of the Punilla Valley, who consulted for a deep papular lesion in the calf, asymptomatic of 2 months of evolution after a trip to Brazil. In both cases, biopsies were obtained, fixed in 10% formalin, included in paraffin blocks and colored with hematoxylin / eosin, Giemsa, PAS and Ziehl Neelsen (ZN). In the histological sections were observed a dense inflammatory infiltrate, with plasma-histio-lymphocyte, visualizing the parasitic forms of extra and intracellular amastigostes. Two cases of cutaneous leishmaniasis are reported, a rare condition in our environment, highlighting the importance of epidemiological antecedents to the correct diagnosis and timely treatment. Las leishmaniasis son un grupo de enfermedades originadas por la infección producida por protozoos del género Leishmania, que parasitan las células del sistema reticuloendotelial. Es transmitida por la picadura de las hembras de mosquitos de los géneros Phlebotomus y Lutzomya, cuyo reservorio son los animales vertebrados. La enfermedad está ampliamente distribuida en América y en nuestro país es endémica en las provincias del norte en donde el agente involucrado es L. brazilensis. En América y Argentina se encuentran las tres formas clínicas: visceral (LV), cutánea (LC) y mucocutánea (LMC). Debido al calentamiento global, a las migraciones poblacionales y deforestaciones, la línea de frontera epidemiológica ha avanzado hacia nuestra provincia lo que nos obliga a tener presente esta patología. El objetivo del presente trabajo fue comunicar dos casos, poco frecuentes en nuestro medio, resaltando la importancia de la correlación clínico patológica y los cambios morfológicos, aveces sutiles, que se observan en la biopsia. De gran importancia es el diagnóstico precoz y tratamiento oportuno, que evita el avance de las lesiones. El primer caso corresponde a un paciente de sexo masculino, 52 años, carpintero, oriundo de Córdoba, capital. Presenta una placa eritematosa en mejilla izquierda de dos meses de evolución, que comenzó luego de un viaje a Jujuy, como una pápula eritematosa, asintomática con aumento de tamaño progresivo; actualmente cubierta de costras serohematicas, mide 3-4cm de diámetro y está rodeado por halo eritematoso-edematoso levemente indurado a la palpación. El segundo caso es un hombre de 76 años, oriundo del Valle de Punilla consulta por una lesión papular profunda en pantorrilla, asintomática de 2 meses de evolución posterior a un viaje a Brasil. En ambos casos se obtienen biopsias, se fijan en formol al 10%, se incluyen en tacos de parafina y se colorean con hematoxilina/eosina, Giemsa, PAS Y Ziehl Neelsen (ZN). En las secciones histológicas se observa un denso infiltrado inflamatorio , plasmo-histio-linfocitario, visualizándose las formas parasitarias de los amastigostes extra e intracelulares. Se comunican dos casos de Leishmaniasis cutánea, una patología poco frecuente en nuestro medio, resaltando la importancia de los antecedentes epidemiológicos para realizar el correcto diagnóstico y tratamiento oportuno. Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2019-10-08 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://revistas.unc.edu.ar/index.php/med/article/view/25616 Revista de la Facultad de Ciencias Médicas de Córdoba.; 2019: Suplemento JIC XX Revista de la Facultad de Ciencias Médicas de Córdoba; 2019: Suplemento JIC XX Revista da Faculdade de Ciências Médicas de Córdoba; 2019: Suplemento JIC XX 1853-0605 0014-6722 10.31053/1853.0605.v76.nSuplemento spa https://revistas.unc.edu.ar/index.php/med/article/view/25616/27357 Derechos de autor 2019 Universidad Nacional de Córdoba https://creativecommons.org/licenses/by-nc/4.0 |