Hip fracture due to osteomalacia secondary to celiac disease
Background: Hip fracture in the young patient is uncommon, but it can have devastating consequences. This pathology in the context of minimal trauma obliges us to carry out a study on calcium metabolism to determine the primary cause. Material and methods: We present a clinical case about an 18-year...
| Autores principales: | , , , , |
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| Formato: | Artículo revista |
| Lenguaje: | Español |
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Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
2022
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| Acceso en línea: | https://revistas.unc.edu.ar/index.php/med/article/view/25541 |
| Aporte de: |
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I10-R327-article-25541 |
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ojs |
| institution |
Universidad Nacional de Córdoba |
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I-10 |
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R-327 |
| container_title_str |
Revista de la Facultad de Ciencias Médicas de Córdoba |
| language |
Español |
| format |
Artículo revista |
| topic |
celiac disease osteomalacia femoral neck fracture fractures spontaneous enfermedad celíaca osteomalacia fracturas del cuello femoral fracturas espontáneas doença celíaca osteomalacia fraturas do colo femoral fraturas espontâneas |
| spellingShingle |
celiac disease osteomalacia femoral neck fracture fractures spontaneous enfermedad celíaca osteomalacia fracturas del cuello femoral fracturas espontáneas doença celíaca osteomalacia fraturas do colo femoral fraturas espontâneas Hernández Fernández, Alberto Pinilla-Gracia, Cristian Rodríguez Nogué, Luis Rodríguez Chacón, Luis Bejarano Lasunción , Carlos Hip fracture due to osteomalacia secondary to celiac disease |
| topic_facet |
celiac disease osteomalacia femoral neck fracture fractures spontaneous enfermedad celíaca osteomalacia fracturas del cuello femoral fracturas espontáneas doença celíaca osteomalacia fraturas do colo femoral fraturas espontâneas |
| author |
Hernández Fernández, Alberto Pinilla-Gracia, Cristian Rodríguez Nogué, Luis Rodríguez Chacón, Luis Bejarano Lasunción , Carlos |
| author_facet |
Hernández Fernández, Alberto Pinilla-Gracia, Cristian Rodríguez Nogué, Luis Rodríguez Chacón, Luis Bejarano Lasunción , Carlos |
| author_sort |
Hernández Fernández, Alberto |
| title |
Hip fracture due to osteomalacia secondary to celiac disease |
| title_short |
Hip fracture due to osteomalacia secondary to celiac disease |
| title_full |
Hip fracture due to osteomalacia secondary to celiac disease |
| title_fullStr |
Hip fracture due to osteomalacia secondary to celiac disease |
| title_full_unstemmed |
Hip fracture due to osteomalacia secondary to celiac disease |
| title_sort |
hip fracture due to osteomalacia secondary to celiac disease |
| description |
Background: Hip fracture in the young patient is uncommon, but it can have devastating consequences. This pathology in the context of minimal trauma obliges us to carry out a study on calcium metabolism to determine the primary cause. Material and methods: We present a clinical case about an 18-year-old male patient who suffered a subcapital fracture of the left hip due to minimal trauma while playing football. The patient was treated urgently by means of closed reduction and internal fixation with two spongy screws. Subsequently, the metabolism study showed a severe vitamin D deficiency (27.1 nmol/L - normal above 75 nmol/L) and high levels of anti-transglutaminase IgA antibodies (2502.40 U/mL). The digestive biopsy confirmed the diagnosis of celiac disease and was treated with a gluten-free diet and calcium and vitamin D supplements. Results: After two years of follow-up, the patient is pain free, with complete hip mobility. There have been no complications (failure of osteosynthesis, avascular necrosis or pseudoarthrosis) and serum levels of vitamin D as well as IgA antibodies against transglutaminase have normalized. Conclusion: In young patients with low energy trauma fractures, vitamin D deficiency must be considered as a possible etiology and the reason for such osteomalacia, such as celiac disease, must be identified. |
| publisher |
Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología |
| publishDate |
2022 |
| url |
https://revistas.unc.edu.ar/index.php/med/article/view/25541 |
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2024-09-03T21:00:46Z |
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I10-R327-article-255412024-08-27T18:25:52Z Hip fracture due to osteomalacia secondary to celiac disease Fractura de cadera debida a osteomalacia secundaria a enfermedad celíaca Fratura de quadril devido a osteomalácia secundária a doença celíaca Hernández Fernández, Alberto Pinilla-Gracia, Cristian Rodríguez Nogué, Luis Rodríguez Chacón, Luis Bejarano Lasunción , Carlos celiac disease osteomalacia femoral neck fracture fractures spontaneous enfermedad celíaca osteomalacia fracturas del cuello femoral fracturas espontáneas doença celíaca osteomalacia fraturas do colo femoral fraturas espontâneas Background: Hip fracture in the young patient is uncommon, but it can have devastating consequences. This pathology in the context of minimal trauma obliges us to carry out a study on calcium metabolism to determine the primary cause. Material and methods: We present a clinical case about an 18-year-old male patient who suffered a subcapital fracture of the left hip due to minimal trauma while playing football. The patient was treated urgently by means of closed reduction and internal fixation with two spongy screws. Subsequently, the metabolism study showed a severe vitamin D deficiency (27.1 nmol/L - normal above 75 nmol/L) and high levels of anti-transglutaminase IgA antibodies (2502.40 U/mL). The digestive biopsy confirmed the diagnosis of celiac disease and was treated with a gluten-free diet and calcium and vitamin D supplements. Results: After two years of follow-up, the patient is pain free, with complete hip mobility. There have been no complications (failure of osteosynthesis, avascular necrosis or pseudoarthrosis) and serum levels of vitamin D as well as IgA antibodies against transglutaminase have normalized. Conclusion: In young patients with low energy trauma fractures, vitamin D deficiency must be considered as a possible etiology and the reason for such osteomalacia, such as celiac disease, must be identified. Antecedentes: La fractura de cadera en el paciente joven es infrecuente, pero puede tener unas consecuencias devastadoras. Esta patología en el contexto de un traumatismo mínimo nos obliga a realizar un estudio sobre el metabolismo del calcio para filiar la causa primaria. Material y método: Presentamos un caso clínico sobre un paciente varón de 18 años que sufrió una fractura subcapital de cadera izquierda debido a un traumatismo mínimo mientras jugaba al fútbol. El paciente fue tratado quirúrgicamente de urgencia mediante reducción cerrada y fijación interna con dos tornillos de esponjosa. Posteriormente, el estudio del metabolismo mostró una deficiencia grave de vitamina D (27.1 nmol/L – normal por encima de 75 nmol/L) y altos niveles de anticuerpos IgA antitransglutaminasa (2502.40 U/mL). La biopsia digestiva confirmó el diagnóstico de enfermedad celíaca por lo que fue tratado con una dieta libre de gluten y suplementos de calcio y vitamina D. Resultados: Tras dos años de seguimiento, el paciente está libre de dolor, con movilidad completa de la cadera. No ha habido complicaciones (fracaso de la osteosíntesis, necrosis avascular o pseudoartrosis) y los niveles séricos de vitamina D así como de los anticuerpos IgA antitransglutaminasa se han normalizado. Conclusión: En pacientes jóvenes que presentan fracturas por traumatismos de baja energía, se ha de tener en cuenta la deficiencia de vitamina D como posible etiología y se debe identificar el motivo de dicha osteomalacia, como es la enfermedad celíaca. Fundamento: A fratura de quadril no paciente jovem é incomum, mas pode ter consequências devastadoras. Essa patologia no contexto de trauma mínimo nos obriga a realizar um estudo sobre o metabolismo do cálcio para determinar a causa primária. Material e método: Apresentamos um caso clínico de um paciente do sexo masculino de 18 anos de idade que sofreu uma fratura subcapital do quadril esquerdo devido a trauma mínimo durante o jogo de futebol. O paciente foi tratado com urgência por meio de redução fechada e fixação interna com dois parafusos esponjosos. Posteriormente, o estudo do metabolismo mostrou uma grave deficiência de vitamina D (27,1 nmol / L - normal acima de 75 nmol / L) e altos níveis de anticorpos IgA contra a transglutaminase (2502,40 U / mL). A biópsia digestiva confirmou o diagnóstico de doença celíaca e foi tratada com dieta sem glúten e suplementos de cálcio e vitamina D. Resultados: Após dois anos de acompanhamento, o paciente está livre da dor, com total mobilidade do quadril. Não houve complicações (falha da osteossíntese, necrose avascular ou pseudoartrose) e os níveis séricos de vitamina D, bem como os anticorpos IgA contra a transglutaminase, se normalizaram. Conclusão: Em pacientes jovens com fraturas por trauma de baixa energia, a deficiência de vitamina D deve ser considerada uma possível etiologia e o motivo dessa osteomalácia, como a doença celíaca, deve ser identificado. Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2022-03-07 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion text/html application/pdf https://revistas.unc.edu.ar/index.php/med/article/view/25541 10.31053/1853.0605.v79.n1.25541 Revista de la Facultad de Ciencias Médicas de Córdoba.; Vol. 79 No. 1 (2022); 61-64 Revista de la Facultad de Ciencias Médicas de Córdoba; Vol. 79 Núm. 1 (2022); 61-64 Revista da Faculdade de Ciências Médicas de Córdoba; v. 79 n. 1 (2022); 61-64 1853-0605 0014-6722 10.31053/1853.0605.v79.n1 spa https://revistas.unc.edu.ar/index.php/med/article/view/25541/37146 https://revistas.unc.edu.ar/index.php/med/article/view/25541/37255 Derechos de autor 2022 Universidad Nacional de Córdoba https://creativecommons.org/licenses/by-nc/4.0 |