Microcephaly infant mortality in Brazil before zika outbreak

Introduction We present temporal and spatial variation of deaths from microcephaly in children under 1 year of age is analyzed at regional, state, and municipal level in the pre-Zika period in Brazil. Materials and Methods Data on births and deaths of infants with microcephaly was obtained from DATA...

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Autores principales: Dipierri, José Edgardo, Schuler-Faccini, Lavinia, Chapur, Valeria Fernanda, Bronberg, Rubén Adrián
Formato: Artículo revista
Lenguaje:Inglés
Español
Publicado: Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2019
Materias:
Infant mortality
microcephaly
Brazil
mortalidad infantil
microcefalia
Brasil
mortalidade infantil
Acceso en línea:https://revistas.unc.edu.ar/index.php/med/article/view/25172
Aporte de:
Revista de la Facultad de Ciencias Médicas de Córdoba de Universidad Nacional de Córdoba
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institution Universidad Nacional de Córdoba
institution_str I-10
repository_str R-327
container_title_str Revista de la Facultad de Ciencias Médicas de Córdoba
language Inglés
Español
format Artículo revista
topic Infant mortality
microcephaly
Brazil
mortalidad infantil
microcefalia
Brasil
mortalidade infantil
microcefalia
Brasil
spellingShingle Infant mortality
microcephaly
Brazil
mortalidad infantil
microcefalia
Brasil
mortalidade infantil
microcefalia
Brasil
Dipierri, José Edgardo
Schuler-Faccini, Lavinia
Chapur, Valeria Fernanda
Bronberg, Rubén Adrián
Microcephaly infant mortality in Brazil before zika outbreak
topic_facet Infant mortality
microcephaly
Brazil
mortalidad infantil
microcefalia
Brasil
mortalidade infantil
microcefalia
Brasil
author Dipierri, José Edgardo
Schuler-Faccini, Lavinia
Chapur, Valeria Fernanda
Bronberg, Rubén Adrián
author_facet Dipierri, José Edgardo
Schuler-Faccini, Lavinia
Chapur, Valeria Fernanda
Bronberg, Rubén Adrián
author_sort Dipierri, José Edgardo
title Microcephaly infant mortality in Brazil before zika outbreak
title_short Microcephaly infant mortality in Brazil before zika outbreak
title_full Microcephaly infant mortality in Brazil before zika outbreak
title_fullStr Microcephaly infant mortality in Brazil before zika outbreak
title_full_unstemmed Microcephaly infant mortality in Brazil before zika outbreak
title_sort microcephaly infant mortality in brazil before zika outbreak
description Introduction We present temporal and spatial variation of deaths from microcephaly in children under 1 year of age is analyzed at regional, state, and municipal level in the pre-Zika period in Brazil. Materials and Methods Data on births and deaths of infants with microcephaly was obtained from DATASUS from 1996 to 2013. Infant mortality rate from microcephaly (IMR-M) was estimated at Region, Federative Unit (UF), and Municipality level. Secular trend (ST) and risk of death variation were estimated using a Poisson regression model. Satscan software was used to obtain a statistic spatial scan for the Poisson model. Results IMR-M shows a non-significant negative ST in the Southeast, South and Central West Regions of Brazil. A greater IMR-M risk of death variation is found in the North and Northeast Regions. Most UFs in the Southeast, South and Central West Regions showed a negative ST, in contrast to what occurs in the UFs of the North and Northeast Regions showed a positive ST. Six high risk significant clusters were found: 3 in the North-Northeast and 3 in the South-SouthWest-Center-West. Conclusions The North and Northeast Regions showed positive ST for IRM-M and higher death risk, which was not observed in the other regions. Cluster distribution for higher IMR-M and risk resembles the distribution of the microcephaly and Zika cases in the outbreak period.
publisher Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
publishDate 2019
url https://revistas.unc.edu.ar/index.php/med/article/view/25172
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spelling I10-R327-article-251722024-08-27T18:25:27Z Microcephaly infant mortality in Brazil before zika outbreak Mortalidad infantil por microcefalia antes del brote de zika en Brasil Mortalidade infantil devido à microcefalia antes do surto de zika no Brasil Dipierri, José Edgardo Schuler-Faccini, Lavinia Chapur, Valeria Fernanda Bronberg, Rubén Adrián Infant mortality microcephaly Brazil mortalidad infantil microcefalia Brasil mortalidade infantil microcefalia Brasil Introduction We present temporal and spatial variation of deaths from microcephaly in children under 1 year of age is analyzed at regional, state, and municipal level in the pre-Zika period in Brazil. Materials and Methods Data on births and deaths of infants with microcephaly was obtained from DATASUS from 1996 to 2013. Infant mortality rate from microcephaly (IMR-M) was estimated at Region, Federative Unit (UF), and Municipality level. Secular trend (ST) and risk of death variation were estimated using a Poisson regression model. Satscan software was used to obtain a statistic spatial scan for the Poisson model. Results IMR-M shows a non-significant negative ST in the Southeast, South and Central West Regions of Brazil. A greater IMR-M risk of death variation is found in the North and Northeast Regions. Most UFs in the Southeast, South and Central West Regions showed a negative ST, in contrast to what occurs in the UFs of the North and Northeast Regions showed a positive ST. Six high risk significant clusters were found: 3 in the North-Northeast and 3 in the South-SouthWest-Center-West. Conclusions The North and Northeast Regions showed positive ST for IRM-M and higher death risk, which was not observed in the other regions. Cluster distribution for higher IMR-M and risk resembles the distribution of the microcephaly and Zika cases in the outbreak period. Introducción Presentamos la variación temporal y espacial de las muertes por microcefalia en niños menores de 1 año de edad que se analizan a nivel regional, estatal y municipal en el período pre-Zika en Brasil. Materiales y métodos Los datos sobre nacimientos y muertes de niños con microcefalia se obtuvieron de DATASUS de 1996 a 2013. La tasa de mortalidad infantil por microcefalia (TMI-M) se estimó a nivel de Región, Unidad de Federativa (UF) y Municipio. La tendencia secular (TS) y la variación del riesgo de muerte se estimaron utilizando un modelo de regresión de Poisson. El análisis estadístico espacial fue realizado por un modelo de Poisson utilizando el software Satscan. Resultados La TMI-M muestra un TS negativo no significativo en las regiones sudeste, sur y centro-oeste de Brasil. Una mayor variación de riesgo de muerte se encuentra en las regiones Norte y Noreste. La mayoría de las UF en las regiones Sureste, Sur y Centro-Oeste mostraron un TS negativa, en contraste con lo que ocurre en las UF de las Regiones Norte y Noreste mostraron una TS positiva. Se encontraron seis agrupamientos significativos de alto riesgo: 3 en el Norte-Noreste y 3 en el Sur-Sur-Oeste-Centro-Oeste. Conclusiones Las regiones Norte y Noreste mostraron una TS positiva para la TMI-M y un mayor riesgo de muerte, que no se observó en las otras regiones. La distribución de los agrupamientos de mayor TMI-M y riesgo se asemeja a la distribución de los casos de microcefalia y Zika en el período del brote. Introdução Apresentamos a variação temporal e espacial das mortes por microcefalia em crianças menores de um ano de idade analisadas nos níveis regional, estadual e municipal no período pré-zika no Brasil. Materiais e métodos Os dados sobre o nascimento e morte de crianças com microcefalia é obtido DATASUS 1996 a 2013. A taxa de mortalidade infantil por microcefalia (IMR-M) foi estimada região nível, UF (UF) e município. A tendência secular (ST) e a variação do risco de morte foram estimadas usando um modelo de regressão de Poisson. A análise estatística espacial foi realizada por um modelo de Poisson utilizando o software Satscan. Resultados O IMR-M mostra um ST negativo não significativo nas regiões sudeste, sul e centro-oeste do Brasil. Uma maior variação no risco de morte da IMR-M é encontrada nas regiões Norte e Nordeste. A maioria das UF nas regiões Sudeste, Sul e Centro-Oeste apresentou um ST negativo, ao contrário do que ocorre na UF das Regiões Norte e Nordeste, que apresentou um ST positivo. Seis grupos significativos de alto risco foram encontrados: 3 no Norte-Nordeste e 3 no Sul-Sul-Oeste-Centro-Oeste. Conclusões As regiões Norte e Nordeste apresentaram um ST positivo para RM e um aumento do risco de morte, o que não foi observado nas demais regiões. A distribuição dos grupos de maior IMR-M e risco assemelha-se à distribuição dos casos de microcefalia e zika no período do surto. Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2019-12-03 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf text/html application/pdf https://revistas.unc.edu.ar/index.php/med/article/view/25172 10.31053/1853.0605.v76.n4.25172 Revista de la Facultad de Ciencias Médicas de Córdoba.; Vol. 76 No. 4 (2019); 217-221 Revista de la Facultad de Ciencias Médicas de Córdoba; Vol. 76 Núm. 4 (2019); 217-221 Revista da Faculdade de Ciências Médicas de Córdoba; v. 76 n. 4 (2019); 217-221 1853-0605 0014-6722 10.31053/1853.0605.v76.n4 eng spa https://revistas.unc.edu.ar/index.php/med/article/view/25172/28383 https://revistas.unc.edu.ar/index.php/med/article/view/25172/28562 https://revistas.unc.edu.ar/index.php/med/article/view/25172/28573 Derechos de autor 2019 Universidad Nacional de Córdoba https://creativecommons.org/licenses/by-nc/4.0

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