Small intestinal plasmacytoid lymphoma. Clinical presentation with acute abdominal pain

Primary tumors of the small intestine are rare; 15-20% of the cases are extranodal lymphomas from B or T cells. Higher Incidence occurs in patients between 21 and 50 years. The clinical symptoms are pain, intestinal obstruction, diarrhea, bleeding or perforated peritonitis. In high-grade lymphomas,...

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Autores principales: Kaplan, R., Burgos, A., Rodriguez, N., Meza Vetanzo, Z., Ortiz, S., Piccinni, DJ.
Formato: Artículo revista
Lenguaje:Español
Publicado: Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2009
Materias:
linfoma
perforación
plasmocitoide
lymphoma
perforation
plasmacytoid configuration
Acceso en línea:https://revistas.unc.edu.ar/index.php/med/article/view/23566
Aporte de:
Revista de la Facultad de Ciencias Médicas de Córdoba de Universidad Nacional de Córdoba
id I10-R327-article-23566
record_format ojs
spelling I10-R327-article-235662024-08-27T18:24:36Z Small intestinal plasmacytoid lymphoma. Clinical presentation with acute abdominal pain Linfoma plasmocitoide de intestino delgado. Presentación Clínica con un cuadro de abdomen agudo Kaplan, R. Burgos, A. Rodriguez, N. Meza Vetanzo, Z. Ortiz, S. Piccinni, DJ. linfoma perforación plasmocitoide lymphoma perforation plasmacytoid configuration Primary tumors of the small intestine are rare; 15-20% of the cases are extranodal lymphomas from B or T cells. Higher Incidence occurs in patients between 21 and 50 years. The clinical symptoms are pain, intestinal obstruction, diarrhea, bleeding or perforated peritonitis. In high-grade lymphomas, the cells are large and pleomorphic, with immunoblastic and plasmacytoid features, and immunopositive for alpha chain immunoglobulins. We reported the case of a 56-year-old patient presented with abdominal pain associated with intestinal perforation. Resections of a 9-centimetres-long segment in the small intestine was performed, which was covered by purulent plaques, with a perforation of 5 mm, surrounded by a greyish-white thick intestinal wall. It can be observed in the microscopy a proliferation of neoplastic cells arranged diffusely and with frequent mitosis. Large areas of immunoblastic and plasmacytoid configuration were evident. The immunomarcation was consistent with a lymphoma of large cells, immunophenotype B, with plasmacytoid development. We highlighted the clinical presentation like acute abdominal pain and its clinical and pathological characteristics, especially in the plasmacytoid development that should differ of the true plasmocytoma. Los tumores primarios de intestino delgado son raros, el 15-20% son linfomas de tipo extranodal que pueden derivar de las células B o T. La edad de mayor incidencia es entre los 21 y 50 años. Clínicamente se presentan con dolor, obstrucción abdominal, diarrea, sangrado o peritonitis perforada. En las formas de alto grado, las células son grandes y pleomórficas, con desarrollo de inmunoblastos y características plasmocitoides, mostrando inmunopositividad para inmunoglobulinas de cadena alfa. Paciente de 56 años con abdomen agudo debido a perforación intestinal. Se le reseca segmento de intestino delgado de 9 cm de largo, cubierto por placas de aspecto purulento, con una perforación de 5mm de diámetro, circundada por una pared intestinal engrosada y gris blanquecina. En la microscopia se observa una proliferación de células neoplásicas, dispuestas difusamente y con frecuente mitosis, destacándose extensas áreas de configuración inmunoblática y plasmocitoide. La inmunomarcación fue consistente con linfoma de células grandes, inmunofenotipo B, con desarrollo plasmocitoide. Presentamos un caso de linfoma plasmocitoide de intestino delgado, variedad neoplásica poco frecuente. Nuestro objetivo es destacar su manifestación como abdomen agudo y hacer hincapié en sus características clínicas y anatomopatológicas, especialmente en el desarrollo plasmocitoide, que debe diferenciarse del verdadero plasmocitoma. Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2009-10-01 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://revistas.unc.edu.ar/index.php/med/article/view/23566 10.31053/1853.0605.v65.n3.23566 Revista de la Facultad de Ciencias Médicas de Córdoba.; Vol. 65 No. 3 (2008); 93-97 Revista de la Facultad de Ciencias Médicas de Córdoba; Vol. 65 Núm. 3 (2008); 93-97 Revista da Faculdade de Ciências Médicas de Córdoba; v. 65 n. 3 (2008); 93-97 1853-0605 0014-6722 10.31053/1853.0605.v65.n3 spa https://revistas.unc.edu.ar/index.php/med/article/view/23566/23251 Derechos de autor 2009 Universidad Nacional de Córdoba https://creativecommons.org/licenses/by-nc/4.0
institution Universidad Nacional de Córdoba
institution_str I-10
repository_str R-327
container_title_str Revista de la Facultad de Ciencias Médicas de Córdoba
language Español
format Artículo revista
topic linfoma
perforación
plasmocitoide
lymphoma
perforation
plasmacytoid configuration
spellingShingle linfoma
perforación
plasmocitoide
lymphoma
perforation
plasmacytoid configuration
Kaplan, R.
Burgos, A.
Rodriguez, N.
Meza Vetanzo, Z.
Ortiz, S.
Piccinni, DJ.
Small intestinal plasmacytoid lymphoma. Clinical presentation with acute abdominal pain
topic_facet linfoma
perforación
plasmocitoide
lymphoma
perforation
plasmacytoid configuration
author Kaplan, R.
Burgos, A.
Rodriguez, N.
Meza Vetanzo, Z.
Ortiz, S.
Piccinni, DJ.
author_facet Kaplan, R.
Burgos, A.
Rodriguez, N.
Meza Vetanzo, Z.
Ortiz, S.
Piccinni, DJ.
author_sort Kaplan, R.
title Small intestinal plasmacytoid lymphoma. Clinical presentation with acute abdominal pain
title_short Small intestinal plasmacytoid lymphoma. Clinical presentation with acute abdominal pain
title_full Small intestinal plasmacytoid lymphoma. Clinical presentation with acute abdominal pain
title_fullStr Small intestinal plasmacytoid lymphoma. Clinical presentation with acute abdominal pain
title_full_unstemmed Small intestinal plasmacytoid lymphoma. Clinical presentation with acute abdominal pain
title_sort small intestinal plasmacytoid lymphoma. clinical presentation with acute abdominal pain
description Primary tumors of the small intestine are rare; 15-20% of the cases are extranodal lymphomas from B or T cells. Higher Incidence occurs in patients between 21 and 50 years. The clinical symptoms are pain, intestinal obstruction, diarrhea, bleeding or perforated peritonitis. In high-grade lymphomas, the cells are large and pleomorphic, with immunoblastic and plasmacytoid features, and immunopositive for alpha chain immunoglobulins. We reported the case of a 56-year-old patient presented with abdominal pain associated with intestinal perforation. Resections of a 9-centimetres-long segment in the small intestine was performed, which was covered by purulent plaques, with a perforation of 5 mm, surrounded by a greyish-white thick intestinal wall. It can be observed in the microscopy a proliferation of neoplastic cells arranged diffusely and with frequent mitosis. Large areas of immunoblastic and plasmacytoid configuration were evident. The immunomarcation was consistent with a lymphoma of large cells, immunophenotype B, with plasmacytoid development. We highlighted the clinical presentation like acute abdominal pain and its clinical and pathological characteristics, especially in the plasmacytoid development that should differ of the true plasmocytoma.
publisher Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
publishDate 2009
url https://revistas.unc.edu.ar/index.php/med/article/view/23566
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AT mezavetanzoz smallintestinalplasmacytoidlymphomaclinicalpresentationwithacuteabdominalpain
AT ortizs smallintestinalplasmacytoidlymphomaclinicalpresentationwithacuteabdominalpain
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first_indexed 2024-09-03T21:00:34Z
last_indexed 2024-09-03T21:00:34Z
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