Colonic carcinomatosis due to lobular carcinoma of the breast: unusual case presentation

Gastrointestinal metastases are rare. May occur years after initial diagnosis and its symptoms are nonspecific, delaying its correct diagnosis and aggravating its prognosis. The most common histological subtype is lobular breast carcinoma. We present a 75-year-old woman with history of left mastecto...

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Detalles Bibliográficos
Autores principales: Bürgesser, María Virginia, Calafat, Patricia, Diller, Ana
Formato: Artículo revista
Lenguaje:Español
Publicado: Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2010
Materias:
tumor
metástasis
tracto gastrointestinal
metastasis
gastrointestinal tract
Acceso en línea:https://revistas.unc.edu.ar/index.php/med/article/view/23424
Aporte de:
Revista de la Facultad de Ciencias Médicas de Córdoba de Universidad Nacional de Córdoba
id I10-R327-article-23424
record_format ojs
institution Universidad Nacional de Córdoba
institution_str I-10
repository_str R-327
container_title_str Revista de la Facultad de Ciencias Médicas de Córdoba
language Español
format Artículo revista
topic tumor
metástasis
tracto gastrointestinal
tumor
metastasis
gastrointestinal tract
spellingShingle tumor
metástasis
tracto gastrointestinal
tumor
metastasis
gastrointestinal tract
Bürgesser, María Virginia
Calafat, Patricia
Diller, Ana
Colonic carcinomatosis due to lobular carcinoma of the breast: unusual case presentation
topic_facet tumor
metástasis
tracto gastrointestinal
tumor
metastasis
gastrointestinal tract
author Bürgesser, María Virginia
Calafat, Patricia
Diller, Ana
author_facet Bürgesser, María Virginia
Calafat, Patricia
Diller, Ana
author_sort Bürgesser, María Virginia
title Colonic carcinomatosis due to lobular carcinoma of the breast: unusual case presentation
title_short Colonic carcinomatosis due to lobular carcinoma of the breast: unusual case presentation
title_full Colonic carcinomatosis due to lobular carcinoma of the breast: unusual case presentation
title_fullStr Colonic carcinomatosis due to lobular carcinoma of the breast: unusual case presentation
title_full_unstemmed Colonic carcinomatosis due to lobular carcinoma of the breast: unusual case presentation
title_sort colonic carcinomatosis due to lobular carcinoma of the breast: unusual case presentation
description Gastrointestinal metastases are rare. May occur years after initial diagnosis and its symptoms are nonspecific, delaying its correct diagnosis and aggravating its prognosis. The most common histological subtype is lobular breast carcinoma. We present a 75-year-old woman with history of left mastectomy six years ago by infiltrating lobular carcinoma. She was treated with tamoxifen for five years. At present, there was no evidence of disease. She attended the hospital for intestinal subocclusion, being admitted for study. A barium enema revealed multiple strictures of the large bowel and a colonoscopy revealed an impassable stricture in the rectum-sigma. Due to the severity of symptoms, underwent total colectomy. The suspected diagnosis was Crohn's disease. The surgical specimen showed multiple stenosis of the light, with thickened wall and mucosa with granulations. Microscopic examination showed transmural infiltration of colonic wall by malignant cells CK7 positive and ER positive. Breast infiltrating lobular carcinoma has more special tendency to affect the digestive tract, even many years after the diagnosis of the primary tumor. In front of a patient with history of breast cancer and gastrointestinal symptoms, its mandatory to consider gastrointestinal metastases, making differential diagnosis with inflammatory bowel disease, infections or primary tumors, as the therapeutic actions are different. 
publisher Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
publishDate 2010
url https://revistas.unc.edu.ar/index.php/med/article/view/23424
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AT calafatpatricia coloniccarcinomatosisduetolobularcarcinomaofthebreastunusualcasepresentation
AT dillerana coloniccarcinomatosisduetolobularcarcinomaofthebreastunusualcasepresentation
AT burgessermariavirginia carcinomatosiscolonicaporcarcinomalobulillardemamapresentacioninusualdeuncaso
AT calafatpatricia carcinomatosiscolonicaporcarcinomalobulillardemamapresentacioninusualdeuncaso
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spelling I10-R327-article-234242024-08-27T18:24:25Z Colonic carcinomatosis due to lobular carcinoma of the breast: unusual case presentation Carcinomatosis colónica por carcinoma lobulillar de mama: presentación inusual de un caso Bürgesser, María Virginia Calafat, Patricia Diller, Ana tumor metástasis tracto gastrointestinal tumor metastasis gastrointestinal tract Gastrointestinal metastases are rare. May occur years after initial diagnosis and its symptoms are nonspecific, delaying its correct diagnosis and aggravating its prognosis. The most common histological subtype is lobular breast carcinoma. We present a 75-year-old woman with history of left mastectomy six years ago by infiltrating lobular carcinoma. She was treated with tamoxifen for five years. At present, there was no evidence of disease. She attended the hospital for intestinal subocclusion, being admitted for study. A barium enema revealed multiple strictures of the large bowel and a colonoscopy revealed an impassable stricture in the rectum-sigma. Due to the severity of symptoms, underwent total colectomy. The suspected diagnosis was Crohn's disease. The surgical specimen showed multiple stenosis of the light, with thickened wall and mucosa with granulations. Microscopic examination showed transmural infiltration of colonic wall by malignant cells CK7 positive and ER positive. Breast infiltrating lobular carcinoma has more special tendency to affect the digestive tract, even many years after the diagnosis of the primary tumor. In front of a patient with history of breast cancer and gastrointestinal symptoms, its mandatory to consider gastrointestinal metastases, making differential diagnosis with inflammatory bowel disease, infections or primary tumors, as the therapeutic actions are different.  Las metástasis en aparato digestivo son infrecuentes. Pueden presentarse años después del diagnóstico inicial y sus síntomas son inespecíficos, haciendo que el diagnóstico correcto se retrase y que empeore el pronóstico de la enfermedad. El subtipo histológico más común es el carcinoma lobulillar de mama. Se presenta una paciente de 75 años de edad, con antecedentes de mastectomía izquierda hacía 6 años por un carcinoma lobulillar infiltrante. Recibió tratamiento con tamoxifeno por 5 años. En la actualidad, no presentaba evidencias de enfermedad. Concurrió a la consulta por cuadro de suboclusión intestinal, siendo internada para su estudio. Un colon por enema reveló múltiples estrecheces del marco colónico y una colonoscopia evidenció una estenosis infranqueable en recto-sigma. Debido a la gravedad del cuadro, fue sometida a colectomía total. La sospecha diagnostica inicial fue enfermedad de Crohn. Al estudiar la pieza quirúrgica se observaron múltiples estenosis de la luz, con mucosa de aspecto mamelonado y pared engrosada. El estudio microscópico evidenció infiltración transmural de la pared colónica por células malignas CK7 positivas y ER positivas. El carcinoma lobulillar infiltrante de mama tiene como particularidad una mayor tendencia a afectar el tubo digestivo, aún muchos años después del diagnóstico del tumor primario. Ante todo paciente con antecedente de cáncer de mama y síntomas gastrointestinales, debe pensarse en metástasis gastrointestinales, realizando, el diagnóstico diferencial con enfermedad inflamatoria intestinal, infecciones o tumores primarios, ya que las acciones terapéuticas son diferentes. Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2010-07-01 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://revistas.unc.edu.ar/index.php/med/article/view/23424 10.31053/1853.0605.v67.n2.23424 Revista de la Facultad de Ciencias Médicas de Córdoba.; Vol. 67 No. 2 (2010); 81-84 Revista de la Facultad de Ciencias Médicas de Córdoba; Vol. 67 Núm. 2 (2010); 81-84 Revista da Faculdade de Ciências Médicas de Córdoba; v. 67 n. 2 (2010); 81-84 1853-0605 0014-6722 10.31053/1853.0605.v67.n2 spa https://revistas.unc.edu.ar/index.php/med/article/view/23424/23146 Derechos de autor 2010 Universidad Nacional de Córdoba https://creativecommons.org/licenses/by-nc/4.0

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