Autoantibodies and Systemic vasculitis
The term vasculitis includes a heterogeneous group of diseases that have in common inflammatory injury of the blood vessels. The evolution of this inflammatory process leads to ischemia or, sometimes, haemorrhage of the organs dependent on these vessels. The location of the affected vessels and tiss...
| Autores principales: | , , |
|---|---|
| Formato: | Artículo revista |
| Lenguaje: | Español |
| Publicado: |
Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
2010
|
| Materias: | |
| Acceso en línea: | https://revistas.unc.edu.ar/index.php/med/article/view/22576 |
| Aporte de: |
| id |
I10-R327-article-22576 |
|---|---|
| record_format |
ojs |
| spelling |
I10-R327-article-225762024-08-27T18:24:05Z Autoantibodies and Systemic vasculitis Autoanticuerpos y vasculitis sistémicas Alba, Paula Bertolacini, María Laura Khasmashta, Munther A. autoantibodies systemic vasculitis autoanticuerpos vasculitis sistémicas The term vasculitis includes a heterogeneous group of diseases that have in common inflammatory injury of the blood vessels. The evolution of this inflammatory process leads to ischemia or, sometimes, haemorrhage of the organs dependent on these vessels. The location of the affected vessels and tissues will determine the appearance of a wide variety of clinical manifestations and, therefore, a very variable prognosis.The different entities grouped under the term vasculitis include Wegener's granulomatosis, Churg-Strauss syndrome, classical panarteritis nodosa, microscopic polyangeitis, Kawasaki disease and classical leukocyte vasculitis, which predominantly affect small and medium-sized vessels. Giant cell arteritis and Takayasu arteritis mainly affect large vessels. We can find primary vasculitis (without association with another underlying disease) or secondary to both infectious processes and autoimmune diseases (rheumatoid arthritis, systemic lupus erythematosus, etc.). Neutrophil anticitoplasma antibodies (ANCA) were initially described by Davies et al. (2) in patients with glomerulonephritis. They are directed against enzymes present in the granules. El término vasculitis incluye un grupo heterogéneo de enfermedades que tienen en común la lesión inflamatoria de los vasos sanguíneos. La evolución de este proceso inflamatorio conduce a la isquemia o, en ocasiones, hemorragia de los órganos dependientes de esos vasos. La localización de los vasos y los tejidos afectados van a determinar la aparición de una amplia variedad de manifestaciones clínicas y, por tanto, de un pronóstico también muy variable. Las distintas entidades agrupadas bajo el término de vasculitis incluyen la granulomatosis de Wegener, el síndrome de Churg-Strauss, panarteritis nodosa clásica, poliangeítis microscópica, enfermedad de Kawasaki y vasculitis leucocito clásticas que afectan predominantemente a vasos de mediano y pequeño tamaño. La arteritis de células gigantes y la arteritis de Takayasu afectan sobre todo a vasos de gran tamaño. Podemos encontrar vasculitis primarias (sin asociación con otra enfermedad subyacente) o secundarias tanto a procesos infecciosos como a enfermedades autoinmunes (artritis reumatoide, lupus eritematoso sistémico, etc.). Los anticuerpos anticitoplasma de neutrófilo (ANCA) fueron descriptos inicialmente por Davies et al. (2) en pacientes con glomerulonefritis. Están dirigidos contra enzimas presentes en los gránulos azuròfilos de los neutrófilos (3,4). Trabajos posteriores han confirmado su asociación con la granulomatosis de Wegener (5,6), con la poliangeítis microscópica, glomerulonefritis idiopática necrotizante y otras enfermedades autoinmunes. Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2010-12-07 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://revistas.unc.edu.ar/index.php/med/article/view/22576 10.31053/1853.0605.v67.n4.22576 Revista de la Facultad de Ciencias Médicas de Córdoba.; Vol. 67 No. 4 (2010); 159-168 Revista de la Facultad de Ciencias Médicas de Córdoba; Vol. 67 Núm. 4 (2010); 159-168 Revista da Faculdade de Ciências Médicas de Córdoba; v. 67 n. 4 (2010); 159-168 1853-0605 0014-6722 10.31053/1853.0605.v67.n4 spa https://revistas.unc.edu.ar/index.php/med/article/view/22576/22191 Derechos de autor 2010 Universidad Nacional de Córdoba https://creativecommons.org/licenses/by-nc/4.0 |
| institution |
Universidad Nacional de Córdoba |
| institution_str |
I-10 |
| repository_str |
R-327 |
| container_title_str |
Revista de la Facultad de Ciencias Médicas de Córdoba |
| language |
Español |
| format |
Artículo revista |
| topic |
autoantibodies systemic vasculitis autoanticuerpos vasculitis sistémicas |
| spellingShingle |
autoantibodies systemic vasculitis autoanticuerpos vasculitis sistémicas Alba, Paula Bertolacini, María Laura Khasmashta, Munther A. Autoantibodies and Systemic vasculitis |
| topic_facet |
autoantibodies systemic vasculitis autoanticuerpos vasculitis sistémicas |
| author |
Alba, Paula Bertolacini, María Laura Khasmashta, Munther A. |
| author_facet |
Alba, Paula Bertolacini, María Laura Khasmashta, Munther A. |
| author_sort |
Alba, Paula |
| title |
Autoantibodies and Systemic vasculitis |
| title_short |
Autoantibodies and Systemic vasculitis |
| title_full |
Autoantibodies and Systemic vasculitis |
| title_fullStr |
Autoantibodies and Systemic vasculitis |
| title_full_unstemmed |
Autoantibodies and Systemic vasculitis |
| title_sort |
autoantibodies and systemic vasculitis |
| description |
The term vasculitis includes a heterogeneous group of diseases that have in common inflammatory injury of the blood vessels. The evolution of this inflammatory process leads to ischemia or, sometimes, haemorrhage of the organs dependent on these vessels. The location of the affected vessels and tissues will determine the appearance of a wide variety of clinical manifestations and, therefore, a very variable prognosis.The different entities grouped under the term vasculitis include Wegener's granulomatosis, Churg-Strauss syndrome, classical panarteritis nodosa, microscopic polyangeitis, Kawasaki disease and classical leukocyte vasculitis, which predominantly affect small and medium-sized vessels. Giant cell arteritis and Takayasu arteritis mainly affect large vessels. We can find primary vasculitis (without association with another underlying disease) or secondary to both infectious processes and autoimmune diseases (rheumatoid arthritis, systemic lupus erythematosus, etc.). Neutrophil anticitoplasma antibodies (ANCA) were initially described by Davies et al. (2) in patients with glomerulonephritis. They are directed against enzymes present in the granules. |
| publisher |
Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología |
| publishDate |
2010 |
| url |
https://revistas.unc.edu.ar/index.php/med/article/view/22576 |
| work_keys_str_mv |
AT albapaula autoantibodiesandsystemicvasculitis AT bertolacinimarialaura autoantibodiesandsystemicvasculitis AT khasmashtamunthera autoantibodiesandsystemicvasculitis AT albapaula autoanticuerposyvasculitissistemicas AT bertolacinimarialaura autoanticuerposyvasculitissistemicas AT khasmashtamunthera autoanticuerposyvasculitissistemicas |
| first_indexed |
2024-09-03T21:00:24Z |
| last_indexed |
2024-09-03T21:00:24Z |
| _version_ |
1809210119677804544 |