Predictive ability of clinical parameters of bacteremia in hemodialysed patients

Background: No clinical events to differentiate bacteteremia from other pathologies in hemodialysis patients therefore the physicians makes diagnosis and treatment decisions based on clinical evidence an local epidemiology Objective: the aim of this work was to study the frequency of microorganism i...

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Autores principales: Egea, Ana L., Vilaró, Mario, De la Fuente, Jorge, Cuestas, Eduardo, Bongiovanni, Maria E.
Formato: Artículo revista
Lenguaje:Español
Publicado: Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2012
Materias:
Acceso en línea:https://revistas.unc.edu.ar/index.php/med/article/view/21119
Aporte de:
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institution Universidad Nacional de Córdoba
institution_str I-10
repository_str R-327
container_title_str Revista de la Facultad de Ciencias Médicas de Córdoba
language Español
format Artículo revista
topic bacteremia
hemodialysis
sensitivity
specificity
clinical variables
bacteriemia
hemodiálisis
variables clínicas
sensibilidad
especificidad
spellingShingle bacteremia
hemodialysis
sensitivity
specificity
clinical variables
bacteriemia
hemodiálisis
variables clínicas
sensibilidad
especificidad
Egea, Ana L.
Vilaró, Mario
De la Fuente, Jorge
Cuestas, Eduardo
Bongiovanni, Maria E.
Predictive ability of clinical parameters of bacteremia in hemodialysed patients
topic_facet bacteremia
hemodialysis
sensitivity
specificity
clinical variables
bacteriemia
hemodiálisis
variables clínicas
sensibilidad
especificidad
author Egea, Ana L.
Vilaró, Mario
De la Fuente, Jorge
Cuestas, Eduardo
Bongiovanni, Maria E.
author_facet Egea, Ana L.
Vilaró, Mario
De la Fuente, Jorge
Cuestas, Eduardo
Bongiovanni, Maria E.
author_sort Egea, Ana L.
title Predictive ability of clinical parameters of bacteremia in hemodialysed patients
title_short Predictive ability of clinical parameters of bacteremia in hemodialysed patients
title_full Predictive ability of clinical parameters of bacteremia in hemodialysed patients
title_fullStr Predictive ability of clinical parameters of bacteremia in hemodialysed patients
title_full_unstemmed Predictive ability of clinical parameters of bacteremia in hemodialysed patients
title_sort predictive ability of clinical parameters of bacteremia in hemodialysed patients
description Background: No clinical events to differentiate bacteteremia from other pathologies in hemodialysis patients therefore the physicians makes diagnosis and treatment decisions based on clinical evidence an local epidemiology Objective: the aim of this work was to study the frequency of microorganism isolated from blood culture of hemodialysis patients with suspected bacteraemia and evaluate Sensitivity (S) and Specificity (E) of medical diagnostic orientation in this cases of suspected Materials and methods: we performed an observational and prospective study for one year in hemodialysis patient with suspected bacteremia. We evaluated blood pressure, temperature (Tº), altered conscious state (AEC), respiratory frequency (FR), chills (ESC),diarrhea (DIARR), blood culture results and microbiological identification. We work with the mean ± standar desviation for continuous variables and frequencies for categorical variables We analyzed S, E, negative predictive value (VPN), positive predictive value (VPP) Resultados: a total of 87 events with suspected bacteremia 34 (39%) were confirmed with positive blood culture the most common microorganisms were cocci Gram positive (CGP) 65%,Most relevant clinical variables were PCP ? 2 (VPN 81%), Tº ? 38 (VPN 76%) and AEC (E 98% y VPP 80%). Conclusions: CGP were the most prevalent microorganisms None of the clinical variables shows high S and E indicating low usefulness as a predictive tool of bacteremia Excepting AEC with E98% and VPP 80% but it would be necessary to evaluate this variable with a more number patient. Results justify to routine HC use like diagnostic tool.
publisher Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
publishDate 2012
url https://revistas.unc.edu.ar/index.php/med/article/view/21119
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spelling I10-R327-article-211192024-08-27T18:22:41Z Predictive ability of clinical parameters of bacteremia in hemodialysed patients Capacidad predictiva de los parámetros clínico de bacteriemia en pacientes hemodializados Egea, Ana L. Vilaró, Mario De la Fuente, Jorge Cuestas, Eduardo Bongiovanni, Maria E. bacteremia hemodialysis sensitivity specificity clinical variables bacteriemia hemodiálisis variables clínicas sensibilidad especificidad Background: No clinical events to differentiate bacteteremia from other pathologies in hemodialysis patients therefore the physicians makes diagnosis and treatment decisions based on clinical evidence an local epidemiology Objective: the aim of this work was to study the frequency of microorganism isolated from blood culture of hemodialysis patients with suspected bacteraemia and evaluate Sensitivity (S) and Specificity (E) of medical diagnostic orientation in this cases of suspected Materials and methods: we performed an observational and prospective study for one year in hemodialysis patient with suspected bacteremia. We evaluated blood pressure, temperature (Tº), altered conscious state (AEC), respiratory frequency (FR), chills (ESC),diarrhea (DIARR), blood culture results and microbiological identification. We work with the mean ± standar desviation for continuous variables and frequencies for categorical variables We analyzed S, E, negative predictive value (VPN), positive predictive value (VPP) Resultados: a total of 87 events with suspected bacteremia 34 (39%) were confirmed with positive blood culture the most common microorganisms were cocci Gram positive (CGP) 65%,Most relevant clinical variables were PCP ? 2 (VPN 81%), Tº ? 38 (VPN 76%) and AEC (E 98% y VPP 80%). Conclusions: CGP were the most prevalent microorganisms None of the clinical variables shows high S and E indicating low usefulness as a predictive tool of bacteremia Excepting AEC with E98% and VPP 80% but it would be necessary to evaluate this variable with a more number patient. Results justify to routine HC use like diagnostic tool. Antecedentes: No existen manifestaciones clínicas propias que permitan diferenciar bacteriemia de otras patologías en pacientes hemodializados (HD), por ello el médico toma decisiones de diagnóstico y tratamiento apoyándose en la clínica y en la evidencia epidemiología local. Objetivos: estudiar la prevalencia de microorganismos aislados de pacientes hemodializados con sospecha de bacteriemia y evaluar Sensibilidad (S) y Especificidad (E), Valor predictivo positivo y negatico (VPP,VPN) de los parámetros clínicos ante la sospecha de bacteriemia. Materiales y Métodos: Se realizó un estudio observacional prospectivo durante el período de un año en pacientes de HD con sospecha de bacteriemia. Se evaluó tensión arterial (Ta), Temperatura mayor o igual a 38 º (Tº?38), alteración del estado de conciencia (AEC), frecuencia respiratoria (FR), escalofrío (ESC), diarrea (DIARR), resultados de Hemocultivo (HC) e identificación microbiológica. Se calculó media ± DE para variables continuas y proporciones con IC95% para variables categóricas, se evalió S, E, VPP y VPN; con IC95%. Resultados: 87 fueron los eventos sospechosos de bacteriemia. En 34 (39%) fueron confirmadas con HC positivos (HC+): los microorganismos mas frecuente fueron: cocos Gram positivos (CGP) 22 (65%). Las variables clínicas más relevantes fueron: Tº ? 38 (S 70 (60-80); VPP 76 (67-85)) y AEC S 98 % (95-101), VPP 80 (72-88) Conclusiones: prevalecieron cocos Gram positivos. La variable AEC demostró ser un predictor sensible para predecir sepsis en pacientes HD. Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2012-09-04 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://revistas.unc.edu.ar/index.php/med/article/view/21119 10.31053/1853.0605.v69.n3.21119 Revista de la Facultad de Ciencias Médicas de Córdoba.; Vol. 69 No. 3 (2012); 135-138 Revista de la Facultad de Ciencias Médicas de Córdoba; Vol. 69 Núm. 3 (2012); 135-138 Revista da Faculdade de Ciências Médicas de Córdoba; v. 69 n. 3 (2012); 135-138 1853-0605 0014-6722 10.31053/1853.0605.v69.n3 spa https://revistas.unc.edu.ar/index.php/med/article/view/21119/20681 Derechos de autor 2012 Universidad Nacional de Córdoba https://creativecommons.org/licenses/by-nc/4.0