Inappropriate response against Hepatitis B vaccine in health personnel of the National Hospital, Paraguay.
Introduction: health personnel are a risk group for acquiring hepatitis B. The vaccine against it is effective but requires evaluation of the immune response with the dosage of anti-HBs.Objectives: to determine the immunological response to the vaccine against hepatitis B in physicians, nurses and m...
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| Autores principales: | , , |
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| Formato: | Artículo revista |
| Lenguaje: | Español |
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Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
2018
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| Materias: | |
| Acceso en línea: | https://revistas.unc.edu.ar/index.php/med/article/view/19060 |
| Aporte de: |
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I10-R327-article-19060 |
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ojs |
| institution |
Universidad Nacional de Córdoba |
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I-10 |
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R-327 |
| container_title_str |
Revista de la Facultad de Ciencias Médicas de Córdoba |
| language |
Español |
| format |
Artículo revista |
| topic |
hepatitis B vaccine anti-HBs health personnel vacuna hepatitis B antiHBs personal de salud |
| spellingShingle |
hepatitis B vaccine anti-HBs health personnel vacuna hepatitis B antiHBs personal de salud Real Delor, Raúl Emilio Villar, Gustavo Rigel Espínola, Julia Inappropriate response against Hepatitis B vaccine in health personnel of the National Hospital, Paraguay. |
| topic_facet |
hepatitis B vaccine anti-HBs health personnel vacuna hepatitis B antiHBs personal de salud |
| author |
Real Delor, Raúl Emilio Villar, Gustavo Rigel Espínola, Julia |
| author_facet |
Real Delor, Raúl Emilio Villar, Gustavo Rigel Espínola, Julia |
| author_sort |
Real Delor, Raúl Emilio |
| title |
Inappropriate response against Hepatitis B vaccine in health personnel of the National Hospital, Paraguay. |
| title_short |
Inappropriate response against Hepatitis B vaccine in health personnel of the National Hospital, Paraguay. |
| title_full |
Inappropriate response against Hepatitis B vaccine in health personnel of the National Hospital, Paraguay. |
| title_fullStr |
Inappropriate response against Hepatitis B vaccine in health personnel of the National Hospital, Paraguay. |
| title_full_unstemmed |
Inappropriate response against Hepatitis B vaccine in health personnel of the National Hospital, Paraguay. |
| title_sort |
inappropriate response against hepatitis b vaccine in health personnel of the national hospital, paraguay. |
| description |
Introduction: health personnel are a risk group for acquiring hepatitis B. The vaccine against it is effective but requires evaluation of the immune response with the dosage of anti-HBs.Objectives: to determine the immunological response to the vaccine against hepatitis B in physicians, nurses and medical students of the National Hospital, Paraguay.Methods: an observational, analytical and cross-sectional study was conducted in a sample of 120 health workers during 2017. The level of anti-HBs was determined with quantitative immunoassay and demographic and clinical variables were recorded, with prior informed consent.Results: the sample was integrated with 79 women and 41 men. The mean age was 28±7 years. Physicians (62.5%), nurses (20%) and medical students (17.5%) were included. The mean BMI was 24.7 ± 3.8 kg/m2. Adequate serum levels of anti-HBs (> 100 IU / mL) were detected in 64% of the health personnel. Obesity was a factor associated with poor response to the vaccine (p 0.02). Sex, age, the time elapsed since the last dose and smoking were factors not significantly associated with the lack of response to the vaccine.Conclusion: inadequate response to HB vaccine was found in 36%. Obesity was significantly associated with poor immunological response. |
| publisher |
Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología |
| publishDate |
2018 |
| url |
https://revistas.unc.edu.ar/index.php/med/article/view/19060 |
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2024-09-03T20:59:20Z |
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2024-09-03T20:59:20Z |
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I10-R327-article-190602024-08-27T18:21:41Z Inappropriate response against Hepatitis B vaccine in health personnel of the National Hospital, Paraguay. Respuesta inadecuada a la vacuna contra la hepatitis B en personal de salud del Hospital Nacional, Paraguay Real Delor, Raúl Emilio Villar, Gustavo Rigel Espínola, Julia hepatitis B vaccine anti-HBs health personnel vacuna hepatitis B antiHBs personal de salud Introduction: health personnel are a risk group for acquiring hepatitis B. The vaccine against it is effective but requires evaluation of the immune response with the dosage of anti-HBs.Objectives: to determine the immunological response to the vaccine against hepatitis B in physicians, nurses and medical students of the National Hospital, Paraguay.Methods: an observational, analytical and cross-sectional study was conducted in a sample of 120 health workers during 2017. The level of anti-HBs was determined with quantitative immunoassay and demographic and clinical variables were recorded, with prior informed consent.Results: the sample was integrated with 79 women and 41 men. The mean age was 28±7 years. Physicians (62.5%), nurses (20%) and medical students (17.5%) were included. The mean BMI was 24.7 ± 3.8 kg/m2. Adequate serum levels of anti-HBs (> 100 IU / mL) were detected in 64% of the health personnel. Obesity was a factor associated with poor response to the vaccine (p 0.02). Sex, age, the time elapsed since the last dose and smoking were factors not significantly associated with the lack of response to the vaccine.Conclusion: inadequate response to HB vaccine was found in 36%. Obesity was significantly associated with poor immunological response. Introducción: el personal de salud es un grupo de riesgo de adquirir la hepatitis B. La vacuna contra la misma es efectiva pero requiere evaluación de la respuesta inmune con el dosaje de antiHBs.Objetivos: determinar la respuesta inmunológica a la vacuna contra la hepatitis B en médicos, enfermeras y estudiantes de Medicina del Hospital Nacional, Paraguay.Métodos: se realizó un estudio observacional, analítico y transversal en una muestra de 120 trabajadores de la salud durante el 2017. Se determinó el nivel de antiHBs con inmunoensayo cuantitativo y se registraron variables demográficas y clínicas, previo consentimiento informado.Resultados: la muestra se conformó con 79 mujeres y 41 varones. La edad media fue 30±8 años. Se incluyeron médicos (62,5%), enfermeras (20%) y estudiantes de Medicina (17,5%). El IMC medio fue 24,7±3,8 kg/m2. Los niveles séricos adecuados de antiHBs (>100 UI/mL) se detectaron en 64% del personal de salud. La obesidad fue un factor asociado a mala respuesta a la vacuna (p 0,02). El sexo, la edad, el tiempo trascurrido desde la última dosis y el tabaquismo no resultaron factores significativamente asociados a la falta de respuesta a la vacuna.Conclusión: la respuesta inadecuada a vacuna HB se halló en 36%. La obesidad se asoció significativamente a la mala respuesta inmunológica. Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2018-09-02 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion estudio observacional prospectivo application/pdf image/jpeg application/pdf application/vnd.openxmlformats-officedocument.wordprocessingml.document application/vnd.openxmlformats-officedocument.spreadsheetml.sheet application/vnd.openxmlformats-officedocument.wordprocessingml.document application/vnd.openxmlformats-officedocument.spreadsheetml.sheet https://revistas.unc.edu.ar/index.php/med/article/view/19060 10.31053/1853.0605.v75.n3.19060 Revista de la Facultad de Ciencias Médicas de Córdoba.; Vol. 75 No. 3 (2018); 150-155 Revista de la Facultad de Ciencias Médicas de Córdoba; Vol. 75 Núm. 3 (2018); 150-155 Revista da Faculdade de Ciências Médicas de Córdoba; v. 75 n. 3 (2018); 150-155 1853-0605 0014-6722 10.31053/1853.0605.v75.n3 spa https://revistas.unc.edu.ar/index.php/med/article/view/19060/20818 https://revistas.unc.edu.ar/index.php/med/article/view/19060/26753 https://revistas.unc.edu.ar/index.php/med/article/view/19060/26754 https://revistas.unc.edu.ar/index.php/med/article/view/19060/26759 https://revistas.unc.edu.ar/index.php/med/article/view/19060/26760 https://revistas.unc.edu.ar/index.php/med/article/view/19060/26761 https://revistas.unc.edu.ar/index.php/med/article/view/19060/26762 Derechos de autor 2018 Universidad Nacional de Córdoba https://creativecommons.org/licenses/by-nc/4.0 |