Filamentous fungal infection in burned patients: retrospective study

Introduction: Infections are the most frequent complications in burn patients. Filamentous fungi have an uncertain place within the statistics, since in our media data regarding their prevalence, causal agents and outcome of those who suffer them remain scarce. The aim of this stud...

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Detalles Bibliográficos
Autores principales: Spesso, Florencia, Aiassa, Susana, Garutti, Alicia, Carballo, Graciela Mariel, Dotto, Gladys
Formato: Artículo revista
Lenguaje:Español
Publicado: Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2018
Materias:
fungi
burn units
mycoses
hongos filamentosos
pacientes quemados
infección fúngica
Acceso en línea:https://revistas.unc.edu.ar/index.php/med/article/view/17841
Aporte de:
Revista de la Facultad de Ciencias Médicas de Córdoba de Universidad Nacional de Córdoba
id I10-R327-article-17841
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institution Universidad Nacional de Córdoba
institution_str I-10
repository_str R-327
container_title_str Revista de la Facultad de Ciencias Médicas de Córdoba
language Español
format Artículo revista
topic fungi
burn units
mycoses
hongos filamentosos
pacientes quemados
infección fúngica
spellingShingle fungi
burn units
mycoses
hongos filamentosos
pacientes quemados
infección fúngica
Spesso, Florencia
Aiassa, Susana
Garutti, Alicia
Carballo, Graciela Mariel
Dotto, Gladys
Filamentous fungal infection in burned patients: retrospective study
topic_facet fungi
burn units
mycoses
hongos filamentosos
pacientes quemados
infección fúngica
author Spesso, Florencia
Aiassa, Susana
Garutti, Alicia
Carballo, Graciela Mariel
Dotto, Gladys
author_facet Spesso, Florencia
Aiassa, Susana
Garutti, Alicia
Carballo, Graciela Mariel
Dotto, Gladys
author_sort Spesso, Florencia
title Filamentous fungal infection in burned patients: retrospective study
title_short Filamentous fungal infection in burned patients: retrospective study
title_full Filamentous fungal infection in burned patients: retrospective study
title_fullStr Filamentous fungal infection in burned patients: retrospective study
title_full_unstemmed Filamentous fungal infection in burned patients: retrospective study
title_sort filamentous fungal infection in burned patients: retrospective study
description Introduction: Infections are the most frequent complications in burn patients. Filamentous fungi have an uncertain place within the statistics, since in our media data regarding their prevalence, causal agents and outcome of those who suffer them remain scarce. The aim of this study was to evaluate the prevalence of fungal infection by filamentous fungi (IHF) in patients hospitalized in burn intensive care unit (BICU), and to review clinical, epidemiological, microbiological and evolutionary characteristics of these patients and to know the frequency and distribution of the isolated fungi. Materials and methods: Retrospective and descriptive study. It includes all individuals admitted in burns intensive care unit (2012-2015), with positive culture for filamentous fungi in skin biopsies and bedsores. Results: A total of 168 patients were admitted in the BICU in a period of 3 years. 90% were major burned and 17% of them developed IHF (29/168).  Aspergillus spp (24%), Fusarium sp (14%), Mucor spp (3%) and various black fungus genera (58%) were the main genera found in cultives. About 24% of the patients with IHF died and Fusarium spp was found in 50% of the cases. The cause of death was irreversible cardiogenic shock with multiorgan failure. Conclusions: Filamentous fungal infection was present in 17% of burned patients. The main isolatte fungi in samples were dematiaceous mould. Mortality among patients was 24%, with Fusarium being the fungus found in the highest number of deaths (50%).
publisher Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
publishDate 2018
url https://revistas.unc.edu.ar/index.php/med/article/view/17841
work_keys_str_mv AT spessoflorencia filamentousfungalinfectioninburnedpatientsretrospectivestudy
AT aiassasusana filamentousfungalinfectioninburnedpatientsretrospectivestudy
AT garuttialicia filamentousfungalinfectioninburnedpatientsretrospectivestudy
AT carballogracielamariel filamentousfungalinfectioninburnedpatientsretrospectivestudy
AT dottogladys filamentousfungalinfectioninburnedpatientsretrospectivestudy
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spelling I10-R327-article-178412024-08-27T18:20:50Z Filamentous fungal infection in burned patients: retrospective study Infección por hongos filamentosos en pacientes quemados: estudio retrospectivo Spesso, Florencia Aiassa, Susana Garutti, Alicia Carballo, Graciela Mariel Dotto, Gladys fungi burn units mycoses hongos filamentosos pacientes quemados infección fúngica Introduction: Infections are the most frequent complications in burn patients. Filamentous fungi have an uncertain place within the statistics, since in our media data regarding their prevalence, causal agents and outcome of those who suffer them remain scarce. The aim of this study was to evaluate the prevalence of fungal infection by filamentous fungi (IHF) in patients hospitalized in burn intensive care unit (BICU), and to review clinical, epidemiological, microbiological and evolutionary characteristics of these patients and to know the frequency and distribution of the isolated fungi. Materials and methods: Retrospective and descriptive study. It includes all individuals admitted in burns intensive care unit (2012-2015), with positive culture for filamentous fungi in skin biopsies and bedsores. Results: A total of 168 patients were admitted in the BICU in a period of 3 years. 90% were major burned and 17% of them developed IHF (29/168).  Aspergillus spp (24%), Fusarium sp (14%), Mucor spp (3%) and various black fungus genera (58%) were the main genera found in cultives. About 24% of the patients with IHF died and Fusarium spp was found in 50% of the cases. The cause of death was irreversible cardiogenic shock with multiorgan failure. Conclusions: Filamentous fungal infection was present in 17% of burned patients. The main isolatte fungi in samples were dematiaceous mould. Mortality among patients was 24%, with Fusarium being the fungus found in the highest number of deaths (50%). Antecedentes: Las infecciones son las complicaciones más frecuentes en los pacientes quemados. Los hongos filamentosos ocupan un lugar incierto dentro de las estadísticas nosocomiales; existen escasos datos sobre la prevalencia de las mismas, los agentes causales y el desenlace de los que las padecen.   Objetivos: El objetivo fue evaluar  prevalencia de la infección por hongos filamentosos (IHF) en pacientes internados en la unidad terapia intensiva de quemados (UTIQ), revisar algunas características clínicas, epidemiológicas, microbiológicas y evolución de estos pacientes;  conocer  la frecuencia y distribución de las especies fúngicas aisladas. Materiales y métodos: Estudio retrospectivo y descriptivo. Se incluyeron todos los individuos que ingresaron a la terapia intensiva de pacientes quemados (2012-2015), con cultivo positivo para hongos filamentosos en biopsias de piel y escaras. Resultados: Un total de 168 de pacientes ingresaron en la unidad intensiva de quemados  en un período de 3 años. El 17% desarrolló IHF (29/168) y el 90% fueron grandes quemados.  Se recuperaron 29 hongos filamentosos (93% de exámenes microscópicos positivos): Aspergillus spp (24%), Fusarium spp (14%), Mucor spp (3%) y diversos géneros de hongos negros (58%).  El 95% presentó entre 1 y 4 infecciones bacterianas además de la infección fúngica en piel. El 24% de los pacientes con IHF falleció. La causa de la muerte fue shock cardiogénico irreversible con falla multiorgánica. Conclusiones: La infección por hongos filamentosos se presentó en el 17% de los pacientes quemados. Los principales hongos causantes de infección  fúngica fueron dematiáceos. La mortalidad entre los pacientes fue del 24%,  siendo Fusarium el hongo  hallado en el mayor número de muertes (50%). Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2018-07-27 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf application/vnd.openxmlformats-officedocument.wordprocessingml.document https://revistas.unc.edu.ar/index.php/med/article/view/17841 10.31053/1853.0605.v75.n2.17841 Revista de la Facultad de Ciencias Médicas de Córdoba.; Vol. 75 No. 2 (2018); 128-133 Revista de la Facultad de Ciencias Médicas de Córdoba; Vol. 75 Núm. 2 (2018); 128-133 Revista da Faculdade de Ciências Médicas de Córdoba; v. 75 n. 2 (2018); 128-133 1853-0605 0014-6722 10.31053/1853.0605.v75.n2 spa https://revistas.unc.edu.ar/index.php/med/article/view/17841/20619 https://revistas.unc.edu.ar/index.php/med/article/view/17841/26698 Derechos de autor 2018 Universidad Nacional de Córdoba https://creativecommons.org/licenses/by-nc/4.0

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