Distribution of Rotavirus G Genotypes during 10 years in children with acute diarrhea of the city of La Rioja, Argentina. Implications for vaccination

Vaccination against rotavirus in Argentina is obligatory from January 2015. From 418 stools in children with acute diarrhea were collected from 2000 to 2010 in city of La Rioja, Argentina, Rotavirus was detected. The 90 rotavirus positive stools samples (21.53%) were amplified by RT-PCR and genotype...

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Autor principal: Cordoba, Patricia Alejandra
Formato: Artículo revista
Lenguaje:Español
Publicado: Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2017
Materias:
rotavirus
diarrhea. La Rioja
Argentina
Genotypes G.
Rotavirus. Diarrea. La Rioja. Argentina. Genotipos G.
Acceso en línea:https://revistas.unc.edu.ar/index.php/med/article/view/15144
Aporte de:
Revista de la Facultad de Ciencias Médicas de Córdoba de Universidad Nacional de Córdoba
id I10-R327-article-15144
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spelling I10-R327-article-151442024-08-27T18:20:18Z Distribution of Rotavirus G Genotypes during 10 years in children with acute diarrhea of the city of La Rioja, Argentina. Implications for vaccination Genotipos G de rotavirus durante 10 años en niños con diarrea aguda de la ciudad de La Rioja, Argentina. Implicancias en la vacunación Cordoba, Patricia Alejandra rotavirus diarrhea. La Rioja Argentina Genotypes G. Rotavirus. Diarrea. La Rioja. Argentina. Genotipos G. Vaccination against rotavirus in Argentina is obligatory from January 2015. From 418 stools in children with acute diarrhea were collected from 2000 to 2010 in city of La Rioja, Argentina, Rotavirus was detected. The 90 rotavirus positive stools samples (21.53%) were amplified by RT-PCR and genotyped by PCR-Mix for G1, G2, G3, G4, G9 and G8. The results show that during 2000-2003, the most frequent genotype was G1 and but since 2008, the G2, G3 and G9 genotypes in single and mixed infections were detected. In La Rioja, the vaccines could prevent dehydration in older children the year but children under one year could be vulnerable to the emergence of strains with genic aberrations due to the implementation of vaccination in our region. La vacunación para rotavirus es obligatoria en Argentina desde enero del 2015. Los genotipos G de rotavirus circulantes previo a la vacunación no fueron estudiados en la Provincia de La Rioja. El objetivo del presente trabajo fue determinar los genotipos G de rotavirus que circulan en La Rioja en niños con diarrea desde 2000 a 2010. Se determinó la presencia de rotavirus del Grupo A por Inmunocromatografía (Biomerieux) en 418 muestras de materias fecales obtenidas en niños con diarrea aguda, hospitalizados y ambulatorios, en ciudad de La Rioja, Argentina. El 40 % de los niños estudiados provenía del interior de la provincia. Las 90 muestras positivas (21,53%) fueron amplificadas por RT-PCR y genotipificadas por Multiplex-PCR para genotipos G1, G2, G3, G4, G9 y G8. Los resultados muestran que el genotipo más frecuente de2000 a2003 fue G1 pero que desde el 2008 se detectaron los genotipos G2, G3 y G9 en infecciones simples y mixtas. Los genotipos G9 y las infecciones mixta, cuádruple y quíntuple, se presentaron en niños menores de un año de vida. Este es el primer reporte de los genotipos G de rotavirus en La Rioja. Los resultados indican que los genotipos G circulantes de rotavirus son compatibles con los que se dispone en la vacuna aunque la presencia de infecciones mixtas y Genotipo G9 en niños menores de un año sugieren una mayor vulnerabilidad de este grupo para la aparición de cepas con derivas génicas durante la implementación de la vacunación en esta Provincia Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2017-12-08 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf application/vnd.openxmlformats-officedocument.spreadsheetml.sheet application/vnd.openxmlformats-officedocument.spreadsheetml.sheet application/vnd.openxmlformats-officedocument.spreadsheetml.sheet https://revistas.unc.edu.ar/index.php/med/article/view/15144 10.31053/1853.0605.v74.n4.15144 Revista de la Facultad de Ciencias Médicas de Córdoba.; Vol. 74 No. 4 (2017); 345-349 Revista de la Facultad de Ciencias Médicas de Córdoba; Vol. 74 Núm. 4 (2017); 345-349 Revista da Faculdade de Ciências Médicas de Córdoba; v. 74 n. 4 (2017); 345-349 1853-0605 0014-6722 10.31053/1853.0605.v74.n4 spa https://revistas.unc.edu.ar/index.php/med/article/view/15144/19490 https://revistas.unc.edu.ar/index.php/med/article/view/15144/26161 https://revistas.unc.edu.ar/index.php/med/article/view/15144/26162 https://revistas.unc.edu.ar/index.php/med/article/view/15144/26163 Derechos de autor 2017 Universidad Nacional de Córdoba https://creativecommons.org/licenses/by-nc/4.0
institution Universidad Nacional de Córdoba
institution_str I-10
repository_str R-327
container_title_str Revista de la Facultad de Ciencias Médicas de Córdoba
language Español
format Artículo revista
topic rotavirus
diarrhea. La Rioja
Argentina
Genotypes G.
Rotavirus. Diarrea. La Rioja. Argentina. Genotipos G.
spellingShingle rotavirus
diarrhea. La Rioja
Argentina
Genotypes G.
Rotavirus. Diarrea. La Rioja. Argentina. Genotipos G.
Cordoba, Patricia Alejandra
Distribution of Rotavirus G Genotypes during 10 years in children with acute diarrhea of the city of La Rioja, Argentina. Implications for vaccination
topic_facet rotavirus
diarrhea. La Rioja
Argentina
Genotypes G.
Rotavirus. Diarrea. La Rioja. Argentina. Genotipos G.
author Cordoba, Patricia Alejandra
author_facet Cordoba, Patricia Alejandra
author_sort Cordoba, Patricia Alejandra
title Distribution of Rotavirus G Genotypes during 10 years in children with acute diarrhea of the city of La Rioja, Argentina. Implications for vaccination
title_short Distribution of Rotavirus G Genotypes during 10 years in children with acute diarrhea of the city of La Rioja, Argentina. Implications for vaccination
title_full Distribution of Rotavirus G Genotypes during 10 years in children with acute diarrhea of the city of La Rioja, Argentina. Implications for vaccination
title_fullStr Distribution of Rotavirus G Genotypes during 10 years in children with acute diarrhea of the city of La Rioja, Argentina. Implications for vaccination
title_full_unstemmed Distribution of Rotavirus G Genotypes during 10 years in children with acute diarrhea of the city of La Rioja, Argentina. Implications for vaccination
title_sort distribution of rotavirus g genotypes during 10 years in children with acute diarrhea of the city of la rioja, argentina. implications for vaccination
description Vaccination against rotavirus in Argentina is obligatory from January 2015. From 418 stools in children with acute diarrhea were collected from 2000 to 2010 in city of La Rioja, Argentina, Rotavirus was detected. The 90 rotavirus positive stools samples (21.53%) were amplified by RT-PCR and genotyped by PCR-Mix for G1, G2, G3, G4, G9 and G8. The results show that during 2000-2003, the most frequent genotype was G1 and but since 2008, the G2, G3 and G9 genotypes in single and mixed infections were detected. In La Rioja, the vaccines could prevent dehydration in older children the year but children under one year could be vulnerable to the emergence of strains with genic aberrations due to the implementation of vaccination in our region.
publisher Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
publishDate 2017
url https://revistas.unc.edu.ar/index.php/med/article/view/15144
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AT cordobapatriciaalejandra genotiposgderotavirusdurante10anosenninoscondiarreaagudadelaciudaddelariojaargentinaimplicanciasenlavacunacion
first_indexed 2024-09-03T20:58:22Z
last_indexed 2024-09-03T20:58:22Z
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