Endocannabinoids (endogenous cannabis), dietary lipids w6 and w3, stress, anxiety, and depression: are they related to each other?
The “essential” polyunsaturated fatty acids (PUFAs), specifically those of the omega-6 and omega-3 families, must be ingested through foods. These lipids are the precursors of numerous molecules with intense biological activity, collectively called “eicosanoids” that include endoca...
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| Autores principales: | , , , , |
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| Formato: | Artículo revista |
| Lenguaje: | Español |
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Asociación de Medicina del Estrés y Psicoinmunoneuroendocrinología
2024
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| Acceso en línea: | https://revistas.unc.edu.ar/index.php/pinelatam/article/view/45877 |
| Aporte de: |
| Sumario: | The “essential” polyunsaturated fatty acids (PUFAs), specifically those of the omega-6 and omega-3 families, must be ingested through foods. These lipids are the precursors of numerous molecules with intense biological activity, collectively called “eicosanoids” that include endocannabinoids (ECB) or endogenous cannabinoids. This article reviews the components of the ECB system, and its functions in health conditions and in situations of chronic stress, depression and anxiety, circumstances usually associated. The effects of exogenous administration of PUFAs and the consequent modulation of the ECB system are also described, both at clinical and experimental level. It is proposed that the ECB system could be favorably modified by exogenous manipulation of PUFAs present in the body, through dietary modifications by food choice. This could potentially facilitate the prevention and management of mood disorders particularly stress, other mood states such as depression, anxiety and similar conditions that affect psycho-emotional health. |
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