Link Between Metabolic Syndrome and Brain Health
Metabolic syndrome is a combination of metabolic disorders, with an estimated prevalence of 20-25% worldwide. According to experimental, clinical and epidemiological evidence, it is associated with the main psychiatric disorders, alterations in the nervous system and neurodegenerative diseases. Obes...
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Asociación de Medicina del Estrés y Psicoinmunoneuroendocrinología
2023
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| Acceso en línea: | https://revistas.unc.edu.ar/index.php/pinelatam/article/view/42021 |
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I10-R287-article-420212024-05-22T19:20:09Z Link Between Metabolic Syndrome and Brain Health Relación entre el síndrome metabólico y la salud cerebral Ligação entre a síndrome metabólica e a saúde cerebral Diaz-Gerevini, Gustavo Priotto, Santiago Barotto, Nelso Astorquiza, Paula Barbosa, Carolina López, Pablo Repossi, Gastón síndrome metabólico trastornos mentales enfermedades neurodegenerativas deterioro cognitivo metabolic syndrome mental disorders neurodegenerative diseases cognitive impairment síndrome metabólica transtornos mentais doenças neurodegenerativas comprometimento cognitivo Metabolic syndrome is a combination of metabolic disorders, with an estimated prevalence of 20-25% worldwide. According to experimental, clinical and epidemiological evidence, it is associated with the main psychiatric disorders, alterations in the nervous system and neurodegenerative diseases. Obesity, which induces chronic inflammatory state, and insulin resistance appear to be the main underlying pathophysiological mechanisms leading to neuroinflammation, neural tissue damage, and cognitive impairment. These issues are discussed with simple proposals of therapeutic interventions: diet, physical activity, sleep improvement and medications with potential neuroprotective effects. El síndrome metabólico es una combinación de alteraciones metabólicas, con una prevalencia estimada en un 20-25% de la población mundial. Según la evidencia experimental, clínica y epidemiológica se asocia con los principales trastornos psiquiátricos, alteraciones en el sistema nervioso y enfermedades neurodegenerativas. La obesidad, que induce un estado inflamatorio crónico, y la insulinoresistencia parecen ser los principales procesos fisiopatológicos basales que llevan a progresiva neuroinflamación, daño en el tejido nervioso y deterioro cognitivo. Se proponen intervenciones terapéuticas simples como: la dieta, actividad física, mejora de la calidad del sueño y ciertos medicamentos con potenciales efectos neuroprotectores. A síndrome metabólica é uma combinação de distúrbios metabólicos, com uma prevalência estimada de 20-25% da população mundial. Segundo evidências experimentais, clínicas e epidemiológicas, está associada aos principais transtornos psiquiátricos, alterações do sistema nervoso e doenças neurodegenerativas. A obesidade, que induz um estado inflamatório crônico, e a resistência à insulina parecem ser os principais processos fisiopatológicos basais que levam à neuroinflamação progressiva, dano ao tecido nervoso e comprometimento cognitivo. Intervenções terapêuticas simples são propostas como: dieta, atividade física, melhora da qualidade do sono e certos medicamentos com potenciais efeitos neuroprotetores. Asociación de Medicina del Estrés y Psicoinmunoneuroendocrinología 2023-07-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion text/html application/pdf https://revistas.unc.edu.ar/index.php/pinelatam/article/view/42021 ark:/s27968677/ewbqp79ki Pinelatinoamericana; Vol. 3 No. 2 (2023); 156-173 Pinelatinoamericana; Vol. 3 Núm. 2 (2023); 156-173 Pinelatinoamericana; V. 3 N. 2 (2023); 156-173 Pinelatinoamericana; v. 3 n. 2 (2023); 156-173 2796-8677 spa https://revistas.unc.edu.ar/index.php/pinelatam/article/view/42021/42179 https://revistas.unc.edu.ar/index.php/pinelatam/article/view/42021/42183 Derechos de autor 2023 Pinelatinoamericana https://creativecommons.org/licenses/by-nc/4.0 |
| institution |
Universidad Nacional de Córdoba |
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I-10 |
| repository_str |
R-287 |
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Pinelatinoamericana |
| language |
Español |
| format |
Artículo revista |
| topic |
síndrome metabólico trastornos mentales enfermedades neurodegenerativas deterioro cognitivo metabolic syndrome mental disorders neurodegenerative diseases cognitive impairment síndrome metabólica transtornos mentais doenças neurodegenerativas comprometimento cognitivo |
| spellingShingle |
síndrome metabólico trastornos mentales enfermedades neurodegenerativas deterioro cognitivo metabolic syndrome mental disorders neurodegenerative diseases cognitive impairment síndrome metabólica transtornos mentais doenças neurodegenerativas comprometimento cognitivo Diaz-Gerevini, Gustavo Priotto, Santiago Barotto, Nelso Astorquiza, Paula Barbosa, Carolina López, Pablo Repossi, Gastón Link Between Metabolic Syndrome and Brain Health |
| topic_facet |
síndrome metabólico trastornos mentales enfermedades neurodegenerativas deterioro cognitivo metabolic syndrome mental disorders neurodegenerative diseases cognitive impairment síndrome metabólica transtornos mentais doenças neurodegenerativas comprometimento cognitivo |
| author |
Diaz-Gerevini, Gustavo Priotto, Santiago Barotto, Nelso Astorquiza, Paula Barbosa, Carolina López, Pablo Repossi, Gastón |
| author_facet |
Diaz-Gerevini, Gustavo Priotto, Santiago Barotto, Nelso Astorquiza, Paula Barbosa, Carolina López, Pablo Repossi, Gastón |
| author_sort |
Diaz-Gerevini, Gustavo |
| title |
Link Between Metabolic Syndrome and Brain Health |
| title_short |
Link Between Metabolic Syndrome and Brain Health |
| title_full |
Link Between Metabolic Syndrome and Brain Health |
| title_fullStr |
Link Between Metabolic Syndrome and Brain Health |
| title_full_unstemmed |
Link Between Metabolic Syndrome and Brain Health |
| title_sort |
link between metabolic syndrome and brain health |
| description |
Metabolic syndrome is a combination of metabolic disorders, with an estimated prevalence of 20-25% worldwide. According to experimental, clinical and epidemiological evidence, it is associated with the main psychiatric disorders, alterations in the nervous system and neurodegenerative diseases. Obesity, which induces chronic inflammatory state, and insulin resistance appear to be the main underlying pathophysiological mechanisms leading to neuroinflammation, neural tissue damage, and cognitive impairment. These issues are discussed with simple proposals of therapeutic interventions: diet, physical activity, sleep improvement and medications with potential neuroprotective effects. |
| publisher |
Asociación de Medicina del Estrés y Psicoinmunoneuroendocrinología |
| publishDate |
2023 |
| url |
https://revistas.unc.edu.ar/index.php/pinelatam/article/view/42021 |
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