Elevated HDL as a stress-related factor in patients with acute coronary heart disease
The aim of this study was to determine the relationship between stress and sociodemographic variables and biomarkers of allostatic load in patients with acute coronary artery disease. Cross-sectional study, in patients with coronary artery disease confirmed by coronary angiography. Stress was measur...
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| Autores principales: | , , , |
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| Formato: | Artículo revista |
| Lenguaje: | Español |
| Publicado: |
Asociación de Medicina del Estrés y Psicoinmunoneuroendocrinología
2023
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| Materias: | |
| Acceso en línea: | https://revistas.unc.edu.ar/index.php/pinelatam/article/view/41862 |
| Aporte de: |
| Sumario: | The aim of this study was to determine the relationship between stress and sociodemographic variables and biomarkers of allostatic load in patients with acute coronary artery disease. Cross-sectional study, in patients with coronary artery disease confirmed by coronary angiography. Stress was measured by means of the perceived stress scale and the sociodemographic and clinical variables were taken from the medical records. Covariables were analyzed using descriptive statistics. Two groups were formed according to the presence or absence of stress at the time of hospitalization; the difference between the groups was evaluated. Correlation was explored by linear regression. A total of 138 patients were recruited, 50% of them were 65 years of age or older, 65.9% were men, acute myocardial infarction was the main diagnosis documented and the most frequent risk factor was arterial hypertension. Twenty-two-point eight percent of patients scored for stress. HDL was higher among patients with stress (Me 45.57) versus those without stress (Me 39.12), being a differentiating factor (p= 0.024). In the multivariate analysis, a positive relationship was found (r: 0.3; p: 0.003) of HDL with stress and an inverse relationship (r: -0.95; p: 0.02) of BMI with HDL in men. The results suggest a direct and significant relationship between elevated HDL levels and stress, and HDL may act as a proinflammatory factor in the acute stage of acute coronary disease. |
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