Elevated HDL as a stress-related factor in patients with acute coronary heart disease
The aim of this study was to determine the relationship between stress and sociodemographic variables and biomarkers of allostatic load in patients with acute coronary artery disease. Cross-sectional study, in patients with coronary artery disease confirmed by coronary angiography. Stress was measur...
| Autores principales: | , , , |
|---|---|
| Formato: | Artículo revista |
| Lenguaje: | Español |
| Publicado: |
Asociación de Medicina del Estrés y Psicoinmunoneuroendocrinología
2023
|
| Materias: | |
| Acceso en línea: | https://revistas.unc.edu.ar/index.php/pinelatam/article/view/41862 |
| Aporte de: |
| id |
I10-R287-article-41862 |
|---|---|
| record_format |
ojs |
| institution |
Universidad Nacional de Córdoba |
| institution_str |
I-10 |
| repository_str |
R-287 |
| container_title_str |
Pinelatinoamericana |
| language |
Español |
| format |
Artículo revista |
| topic |
enfermedad coronaria estrés biomarcadores colesterol HDL carga alostática coronary disease stress biomarkers HDL dysfunctional HDL allostatic load doença cardíaca coronária stress biomarcadores colesterol HDL carga alostática |
| spellingShingle |
enfermedad coronaria estrés biomarcadores colesterol HDL carga alostática coronary disease stress biomarkers HDL dysfunctional HDL allostatic load doença cardíaca coronária stress biomarcadores colesterol HDL carga alostática Henao Pérez, Marcela López Medina, Diana Carolina Henao Pérez, Julieta Lemos , Mariantonia Elevated HDL as a stress-related factor in patients with acute coronary heart disease |
| topic_facet |
enfermedad coronaria estrés biomarcadores colesterol HDL carga alostática coronary disease stress biomarkers HDL dysfunctional HDL allostatic load doença cardíaca coronária stress biomarcadores colesterol HDL carga alostática |
| author |
Henao Pérez, Marcela López Medina, Diana Carolina Henao Pérez, Julieta Lemos , Mariantonia |
| author_facet |
Henao Pérez, Marcela López Medina, Diana Carolina Henao Pérez, Julieta Lemos , Mariantonia |
| author_sort |
Henao Pérez, Marcela |
| title |
Elevated HDL as a stress-related factor in patients with acute coronary heart disease |
| title_short |
Elevated HDL as a stress-related factor in patients with acute coronary heart disease |
| title_full |
Elevated HDL as a stress-related factor in patients with acute coronary heart disease |
| title_fullStr |
Elevated HDL as a stress-related factor in patients with acute coronary heart disease |
| title_full_unstemmed |
Elevated HDL as a stress-related factor in patients with acute coronary heart disease |
| title_sort |
elevated hdl as a stress-related factor in patients with acute coronary heart disease |
| description |
The aim of this study was to determine the relationship between stress and sociodemographic variables and biomarkers of allostatic load in patients with acute coronary artery disease. Cross-sectional study, in patients with coronary artery disease confirmed by coronary angiography. Stress was measured by means of the perceived stress scale and the sociodemographic and clinical variables were taken from the medical records. Covariables were analyzed using descriptive statistics. Two groups were formed according to the presence or absence of stress at the time of hospitalization; the difference between the groups was evaluated. Correlation was explored by linear regression. A total of 138 patients were recruited, 50% of them were 65 years of age or older, 65.9% were men, acute myocardial infarction was the main diagnosis documented and the most frequent risk factor was arterial hypertension. Twenty-two-point eight percent of patients scored for stress. HDL was higher among patients with stress (Me 45.57) versus those without stress (Me 39.12), being a differentiating factor (p= 0.024). In the multivariate analysis, a positive relationship was found (r: 0.3; p: 0.003) of HDL with stress and an inverse relationship (r: -0.95; p: 0.02) of BMI with HDL in men. The results suggest a direct and significant relationship between elevated HDL levels and stress, and HDL may act as a proinflammatory factor in the acute stage of acute coronary disease. |
| publisher |
Asociación de Medicina del Estrés y Psicoinmunoneuroendocrinología |
| publishDate |
2023 |
| url |
https://revistas.unc.edu.ar/index.php/pinelatam/article/view/41862 |
| work_keys_str_mv |
AT henaoperezmarcela elevatedhdlasastressrelatedfactorinpatientswithacutecoronaryheartdisease AT lopezmedinadianacarolina elevatedhdlasastressrelatedfactorinpatientswithacutecoronaryheartdisease AT henaoperezjulieta elevatedhdlasastressrelatedfactorinpatientswithacutecoronaryheartdisease AT lemosmariantonia elevatedhdlasastressrelatedfactorinpatientswithacutecoronaryheartdisease AT henaoperezmarcela hdlelevadocomofactorrelacionadoalestresenpacientesconenfermedadcoronariaaguda AT lopezmedinadianacarolina hdlelevadocomofactorrelacionadoalestresenpacientesconenfermedadcoronariaaguda AT henaoperezjulieta hdlelevadocomofactorrelacionadoalestresenpacientesconenfermedadcoronariaaguda AT lemosmariantonia hdlelevadocomofactorrelacionadoalestresenpacientesconenfermedadcoronariaaguda AT henaoperezmarcela hdlelevadocomoumfatorrelacionadoaoestresseempacientescomdoencacoronarianaaguda AT lopezmedinadianacarolina hdlelevadocomoumfatorrelacionadoaoestresseempacientescomdoencacoronarianaaguda AT henaoperezjulieta hdlelevadocomoumfatorrelacionadoaoestresseempacientescomdoencacoronarianaaguda AT lemosmariantonia hdlelevadocomoumfatorrelacionadoaoestresseempacientescomdoencacoronarianaaguda |
| first_indexed |
2024-09-03T22:41:59Z |
| last_indexed |
2024-09-03T22:41:59Z |
| _version_ |
1809216511273861120 |
| spelling |
I10-R287-article-418622024-05-22T19:19:17Z Elevated HDL as a stress-related factor in patients with acute coronary heart disease HDL elevado como factor relacionado al estrés en pacientes con enfermedad coronaria aguda HDL elevado como um fator relacionado ao estresse em pacientes com doença coronariana aguda Henao Pérez, Marcela López Medina, Diana Carolina Henao Pérez, Julieta Lemos , Mariantonia enfermedad coronaria estrés biomarcadores colesterol HDL carga alostática coronary disease stress biomarkers HDL dysfunctional HDL allostatic load doença cardíaca coronária stress biomarcadores colesterol HDL carga alostática The aim of this study was to determine the relationship between stress and sociodemographic variables and biomarkers of allostatic load in patients with acute coronary artery disease. Cross-sectional study, in patients with coronary artery disease confirmed by coronary angiography. Stress was measured by means of the perceived stress scale and the sociodemographic and clinical variables were taken from the medical records. Covariables were analyzed using descriptive statistics. Two groups were formed according to the presence or absence of stress at the time of hospitalization; the difference between the groups was evaluated. Correlation was explored by linear regression. A total of 138 patients were recruited, 50% of them were 65 years of age or older, 65.9% were men, acute myocardial infarction was the main diagnosis documented and the most frequent risk factor was arterial hypertension. Twenty-two-point eight percent of patients scored for stress. HDL was higher among patients with stress (Me 45.57) versus those without stress (Me 39.12), being a differentiating factor (p= 0.024). In the multivariate analysis, a positive relationship was found (r: 0.3; p: 0.003) of HDL with stress and an inverse relationship (r: -0.95; p: 0.02) of BMI with HDL in men. The results suggest a direct and significant relationship between elevated HDL levels and stress, and HDL may act as a proinflammatory factor in the acute stage of acute coronary disease. El objetivo de este estudio fue determinar la relación entre estrés con variables sociodemográficas y biomarcadores de carga alostática, en pacientes con enfermedad coronaria aguda. Es un estudio cross sectional, en pacientes con enfermedad coronaria confirmada por coronariografía. El estrés se midió a través de la escala de estrés percibido y las variables sociodemográficas y clínicas fueron tomadas de las historias clínicas. Por medio de estadística descriptiva se analizaron las covariables. Se conformaron dos grupos según la presencia o no de estrés, al momento de la hospitalización; se evaluó la diferencia entre los grupos. Se exploró la correlación por medio de regresión lineal. Se reclutaron 138 pacientes, 50% de ellos tenían 65 o más años, 65.9% eran hombres, el infarto agudo de miocardio fue el principal diagnostico documentado y el factor de riesgo más frecuente fue la hipertensión arterial. El 22,8% de los pacientes puntuaron para estrés. El HDL fue mayor entre los pacientes con estrés (Me 45,57) frente a aquellos sin estrés (Me 39,12), siendo un factor diferenciador (p= 0,024). En el análisis multivariable se encontró relación positiva (r: 0.3; p: 0.003) del HDL con el estrés y una relación inversa (r: -0.95; p: 0.02) del IMC con el HDL en los hombres. Los resultados sugieren una relación directa y significativa entre niveles elevados de HDL y el estrés, pudiendo actuar el HDL como un factor proinflamatorio en el momento agudo de la enfermedad coronaria aguda. O objetivo deste estudo foi determinar a relação entre stress e variáveis sociodemográficas e biomarcadores de carga alostática em doentes com doença arterial coronária aguda. Estudo transversal, em pacientes com doença arterial coronária confirmada por angiografia coronária. O stress foi medido através da escala de stress percebido e as variáveis sociodemográficas e clínicas foram retiradas dos registos médicos. As covariáveis foram analisadas através de estatística descritiva. Foram formados dois grupos de acordo com a presença ou ausência de stress no momento da hospitalização; foi avaliada a diferença entre os grupos. A correlação foi explorada por regressão linear. Foram recrutados 138 doentes, 50% dos quais tinham 65 anos ou mais, 65,9% eram do sexo masculino, o enfarte agudo do miocárdio foi o principal diagnóstico documentado e o fator de risco mais frequente foi a hipertensão arterial. 22,8% dos doentes foram submetidos a stress. O HDL foi mais elevado nos doentes com stress (Me 45,57) em comparação com os doentes sem stress (Me 39,12), sendo um fator diferenciador (p= 0,024). A análise multivariada encontrou uma relação positiva (r: 0,3; p: 0,003) do HDL com o stress e uma relação inversa (r: -0,95; p: 0,02) do IMC com o HDL nos homens. Os resultados sugerem uma relação direta e significativa entre níveis elevados de HDL e stress, e o HDL pode atuar como um fator pró-inflamatório na fase aguda da doença coronária aguda. Asociación de Medicina del Estrés y Psicoinmunoneuroendocrinología 2023-07-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion text/html application/pdf https://revistas.unc.edu.ar/index.php/pinelatam/article/view/41862 ark:/s27968677/6q9kbx228 Pinelatinoamericana; Vol. 3 No. 2 (2023); 138-155 Pinelatinoamericana; Vol. 3 Núm. 2 (2023); 138-155 Pinelatinoamericana; V. 3 N. 2 (2023); 138-155 Pinelatinoamericana; v. 3 n. 2 (2023); 138-155 2796-8677 spa https://revistas.unc.edu.ar/index.php/pinelatam/article/view/41862/42015 https://revistas.unc.edu.ar/index.php/pinelatam/article/view/41862/42016 Derechos de autor 2023 Pinelatinoamericana https://creativecommons.org/licenses/by-nc/4.0 |