Implication of diet in the composition and variability of the intestinal microbiota: its effects on obesity and anxiety
The gut microbiota (GM) is a complex community of billions of commensal microorganisms, conditioned by perinatal, postnatal, environmental and pharmacological factors, with significant metabolic activity. Its dysbiosis is associated with a greater predisposition to intestinal, allergic and metabolic...
| Autores principales: | , |
|---|---|
| Formato: | Artículo revista |
| Lenguaje: | Español |
| Publicado: |
Asociación de Medicina del Estrés y Psicoinmunoneuroendocrinología
2022
|
| Materias: | |
| Acceso en línea: | https://revistas.unc.edu.ar/index.php/pinelatam/article/view/38373 |
| Aporte de: |
| id |
I10-R287-article-38373 |
|---|---|
| record_format |
ojs |
| institution |
Universidad Nacional de Córdoba |
| institution_str |
I-10 |
| repository_str |
R-287 |
| container_title_str |
Pinelatinoamericana |
| language |
Español |
| format |
Artículo revista |
| topic |
microbiota intestinal dieta obesidad ansiedad gastrointestinal microbiome dieta obesity anxiety microbioma intestinal diet obesidade ansiedade |
| spellingShingle |
microbiota intestinal dieta obesidad ansiedad gastrointestinal microbiome dieta obesity anxiety microbioma intestinal diet obesidade ansiedade Oberto, María Georgina Defagó, María Daniela Implication of diet in the composition and variability of the intestinal microbiota: its effects on obesity and anxiety |
| topic_facet |
microbiota intestinal dieta obesidad ansiedad gastrointestinal microbiome dieta obesity anxiety microbioma intestinal diet obesidade ansiedade |
| author |
Oberto, María Georgina Defagó, María Daniela |
| author_facet |
Oberto, María Georgina Defagó, María Daniela |
| author_sort |
Oberto, María Georgina |
| title |
Implication of diet in the composition and variability of the intestinal microbiota: its effects on obesity and anxiety |
| title_short |
Implication of diet in the composition and variability of the intestinal microbiota: its effects on obesity and anxiety |
| title_full |
Implication of diet in the composition and variability of the intestinal microbiota: its effects on obesity and anxiety |
| title_fullStr |
Implication of diet in the composition and variability of the intestinal microbiota: its effects on obesity and anxiety |
| title_full_unstemmed |
Implication of diet in the composition and variability of the intestinal microbiota: its effects on obesity and anxiety |
| title_sort |
implication of diet in the composition and variability of the intestinal microbiota: its effects on obesity and anxiety |
| description |
The gut microbiota (GM) is a complex community of billions of commensal microorganisms, conditioned by perinatal, postnatal, environmental and pharmacological factors, with significant metabolic activity. Its dysbiosis is associated with a greater predisposition to intestinal, allergic and metabolic diseases, as well as to mental, autoimmune diseases and some types of cancer.
Stress and anxiety may affect the diversity of GM, with increased permeability to pathogens, minor presence of Firmicutes, Bacteroidetes and Lactobacillus spp. and a persistent activation of the appetite that can trigger excess weight. The microbial ecology is different between healthy and obese, affecting energy homeostasis with a consequent higher concentration of short-chain fatty acids (SCFA) and fat storage. On the other hand, healthy food patterns are associated to F. prausnitzii and Prevotella copri, linked with beneficial cardiometabolic markers and negative correlation with visceral fat.
Although it has been shown that diet actively participates in the structural regulation of GM, with implications for mood, stress and anxiety, and the possible therapeutic effects derived from its modulation with probiotics (i.e. L. acidophilus, L. casei and B. bifidum), more prospective studies in humans are required for the planning of comprehensive and personalized dietary interventions. |
| publisher |
Asociación de Medicina del Estrés y Psicoinmunoneuroendocrinología |
| publishDate |
2022 |
| url |
https://revistas.unc.edu.ar/index.php/pinelatam/article/view/38373 |
| work_keys_str_mv |
AT obertomariageorgina implicationofdietinthecompositionandvariabilityoftheintestinalmicrobiotaitseffectsonobesityandanxiety AT defagomariadaniela implicationofdietinthecompositionandvariabilityoftheintestinalmicrobiotaitseffectsonobesityandanxiety AT obertomariageorgina implicanciadeladietaenlacomposicionyvariabilidaddelamicrobiotaintestinalsusefectosenlaobesidadyansiedad AT defagomariadaniela implicanciadeladietaenlacomposicionyvariabilidaddelamicrobiotaintestinalsusefectosenlaobesidadyansiedad AT obertomariageorgina implicacaodadietanacomposicaoevariabilidadedamicrobiotaintestinalseusefeitosnaobesidadeenaansiedade AT defagomariadaniela implicacaodadietanacomposicaoevariabilidadedamicrobiotaintestinalseusefeitosnaobesidadeenaansiedade |
| first_indexed |
2024-09-03T22:41:54Z |
| last_indexed |
2024-09-03T22:41:54Z |
| _version_ |
1809216505884180480 |
| spelling |
I10-R287-article-383732024-05-22T19:44:11Z Implication of diet in the composition and variability of the intestinal microbiota: its effects on obesity and anxiety Implicancia de la dieta en la composición y variabilidad de la microbiota intestinal: sus efectos en la obesidad y ansiedad Implicação da dieta na composição e variabilidade da microbiota intestinal: seus efeitos na obesidade e na ansiedade Oberto, María Georgina Defagó, María Daniela microbiota intestinal dieta obesidad ansiedad gastrointestinal microbiome dieta obesity anxiety microbioma intestinal diet obesidade ansiedade The gut microbiota (GM) is a complex community of billions of commensal microorganisms, conditioned by perinatal, postnatal, environmental and pharmacological factors, with significant metabolic activity. Its dysbiosis is associated with a greater predisposition to intestinal, allergic and metabolic diseases, as well as to mental, autoimmune diseases and some types of cancer. Stress and anxiety may affect the diversity of GM, with increased permeability to pathogens, minor presence of Firmicutes, Bacteroidetes and Lactobacillus spp. and a persistent activation of the appetite that can trigger excess weight. The microbial ecology is different between healthy and obese, affecting energy homeostasis with a consequent higher concentration of short-chain fatty acids (SCFA) and fat storage. On the other hand, healthy food patterns are associated to F. prausnitzii and Prevotella copri, linked with beneficial cardiometabolic markers and negative correlation with visceral fat. Although it has been shown that diet actively participates in the structural regulation of GM, with implications for mood, stress and anxiety, and the possible therapeutic effects derived from its modulation with probiotics (i.e. L. acidophilus, L. casei and B. bifidum), more prospective studies in humans are required for the planning of comprehensive and personalized dietary interventions. La microbiota intestinal (MI) es una compleja comunidad de billones de microorganismos comensales, condicionada por factores perinatales, posnatales, medioambientales y farmacológicos, con importante actividad metabólica. Su disbiosis se asocia a mayor predisposición a enfermedades intestinales, alérgicas y metabólicas, como así también a enfermedades mentales, autoinmunes y algunos tipos de cáncer. El estrés y la ansiedad afectan la diversidad de la MI, aumentándose la permeabilidad a patógenos, menos presencia de Firmicutes, Bacteroidetes y Lactobacillus spp. y una activación persistente del apetito que puede desencadenar en exceso de peso. La ecología microbiana es diferente entre sanos y obesos, afectando la homeostasis energética con una consecuente mayor concentración de ácidos grasos de cadena corta (AGCC) y almacenamiento de grasa. Por otro lado, patrones alimentarios saludables se vinculan con F. prausnitzii y Prevotella copri, asociadas con marcadores cardiometabólicos beneficiosos y correlación negativa con la grasa visceral. Se ha demostrado que la calidad y cantidad de los componentes de la dieta participan activamente en la regulación del microbioma estructural de la MI, con implicancias en el estado de ánimo, el estrés y la ansiedad y los posibles efectos terapéuticos derivados de su modulación con probióticos (i.e. L. acidophilus, L. casei y B. Bifidum) Sin embargo, se requieren más estudios prospectivos en seres humanos para la planificación de intervenciones dietéticas integrales y personalizadas. A microbiota intestinal (MI) é uma comunidade complexa de bilhões de microrganismos comensais, condicionada por fatores perinatais, pós-natais, ambientais e farmacológicos, com significativa atividade metabólica. Sua disbiose está associada a uma maior predisposição a doenças intestinais, alérgicas e metabólicas, assim como a doenças mentais, autoimunes e alguns tipos de câncer. Estresse e ansiedade afetam a diversidade de MI, com maior permeabilidade a patógenos, menor presença de Firmicutes, Bacteroidetes e Lactobacillus spp. e uma ativação persistente do apetite que pode desencadear o excesso de peso. A ecologia microbiana é diferente entre saudáveis e obesos, afetando a homeostase energética com conseqüente maior concentração de ácidos graxos de cadeia curta (AGCC) e armazenamento de gordura. Por outro lado, padrões alimentares saudáveis estão ligados a F. prausnitzii e Prevotella copri, associados a marcadores cardiometabólicos benéficos e correlação negativa com gordura visceral. Embora tenha sido demonstrado que a dieta participa ativamente na regulação estrutural do IM, com implicações no humor, estresse e ansiedade, e os possíveis efeitos terapêuticos derivados de sua modulação com probióticos (ou seja, L. acidophilus, L. casei e B. bifidum), mais estudos prospectivos em humanos são necessários para o planejamento de intervenções dietéticas abrangentes e personalizadas. Asociación de Medicina del Estrés y Psicoinmunoneuroendocrinología 2022-07-29 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf text/html https://revistas.unc.edu.ar/index.php/pinelatam/article/view/38373 ark:/s27968677/cwov78r28 Pinelatinoamericana; Vol. 2 No. 2 (2022); 137-152 Pinelatinoamericana; Vol. 2 Núm. 2 (2022); 137-152 Pinelatinoamericana; V. 2 N. 2 (2022); 137-152 Pinelatinoamericana; v. 2 n. 2 (2022); 137-152 2796-8677 spa https://revistas.unc.edu.ar/index.php/pinelatam/article/view/38373/38409 https://revistas.unc.edu.ar/index.php/pinelatam/article/view/38373/38384 Derechos de autor 2022 Pinelatinoamericana https://creativecommons.org/licenses/by-nc/4.0 |