Low degree inflammation in the Nervous System and chronic stress: cellular and molecular pathophysiology

It will be reviewed how the typical cascade of inflammation begins emphasizing that this normal sequential process conforms the final path of the organism to recover its homeostasis being a global response of the whole body, evolutionarily preserved against macro and microscopic injuries. The develo...

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Detalles Bibliográficos
Autor principal: Eynard, Aldo R.
Formato: Artículo revista
Lenguaje:Español
Publicado: Asociación de Medicina del Estrés y Psicoinmunoneuroendocrinología 2021
Materias:
inflamación de bajo grado
sistema nervioso
estrés
stress
low grade inflammation
nervous system
estresse
inflamação de baixo grau
sistema nervoso
Acceso en línea:https://revistas.unc.edu.ar/index.php/pinelatam/article/view/35444
Aporte de:
Pinelatinoamericana de Universidad Nacional de Córdoba
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record_format ojs
institution Universidad Nacional de Córdoba
institution_str I-10
repository_str R-287
container_title_str Pinelatinoamericana
language Español
format Artículo revista
topic inflamación de bajo grado
sistema nervioso
estrés
stress
low grade inflammation
nervous system
estresse
inflamação de baixo grau
sistema nervoso
spellingShingle inflamación de bajo grado
sistema nervioso
estrés
stress
low grade inflammation
nervous system
estresse
inflamação de baixo grau
sistema nervoso
Eynard, Aldo R.
Low degree inflammation in the Nervous System and chronic stress: cellular and molecular pathophysiology
topic_facet inflamación de bajo grado
sistema nervioso
estrés
stress
low grade inflammation
nervous system
estresse
inflamação de baixo grau
sistema nervoso
author Eynard, Aldo R.
author_facet Eynard, Aldo R.
author_sort Eynard, Aldo R.
title Low degree inflammation in the Nervous System and chronic stress: cellular and molecular pathophysiology
title_short Low degree inflammation in the Nervous System and chronic stress: cellular and molecular pathophysiology
title_full Low degree inflammation in the Nervous System and chronic stress: cellular and molecular pathophysiology
title_fullStr Low degree inflammation in the Nervous System and chronic stress: cellular and molecular pathophysiology
title_full_unstemmed Low degree inflammation in the Nervous System and chronic stress: cellular and molecular pathophysiology
title_sort low degree inflammation in the nervous system and chronic stress: cellular and molecular pathophysiology
description It will be reviewed how the typical cascade of inflammation begins emphasizing that this normal sequential process conforms the final path of the organism to recover its homeostasis being a global response of the whole body, evolutionarily preserved against macro and microscopic injuries. The development and progression of chronic diseases or conditions, particularly chronic stress, closely related to low-grade or subclinical inflammations induced by several aggressors (physical, environmental or psychological) will be discussed. The cross-talk among basic cellular and molecular aspects of inflammation, the local and systemic immune processes regulating pro- and anti-inflammatory molecules of innate and acquired immunity will be analyzed as well it will be the interconnected feedback among neuronal pathways, their encephalic nuclei and endocrine responses in healthy conditions. The systemic alterations that develop in these systems when occurs a sustained aggression by chronic stress will be pointed out. It is concluded that the professionals who are members of the health team must work together and guide adults in order to educate their children to acquire healthy lifestyle habits that may avoid, prevent and alleviate the condition of chronic inflammation and stress.
publisher Asociación de Medicina del Estrés y Psicoinmunoneuroendocrinología
publishDate 2021
url https://revistas.unc.edu.ar/index.php/pinelatam/article/view/35444
work_keys_str_mv AT eynardaldor lowdegreeinflammationinthenervoussystemandchronicstresscellularandmolecularpathophysiology
AT eynardaldor inflamaciondebajogradoenelsistemanerviosoyestrescronicoaspectoscelularesymolecularesbasicosensufisiopatologia
AT eynardaldor inflamacaodebaixograunosistemanervosoeestressecronicoaspectoscelularesemolecularesbasicosemsuafisiopatologia
first_indexed 2024-09-03T22:41:50Z
last_indexed 2024-09-03T22:41:50Z
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spelling I10-R287-article-354442024-05-22T19:54:50Z Low degree inflammation in the Nervous System and chronic stress: cellular and molecular pathophysiology Inflamación de “bajo grado” en el Sistema Nervioso y estrés crónico: aspectos celulares y moleculares básicos en su fisiopatología Inflamação de "baixo grau" no Sistema Nervoso e estresse crônico: aspectos celulares e moleculares básicos em sua fisiopatologia Eynard, Aldo R. inflamación de bajo grado sistema nervioso estrés stress low grade inflammation nervous system estresse inflamação de baixo grau sistema nervoso It will be reviewed how the typical cascade of inflammation begins emphasizing that this normal sequential process conforms the final path of the organism to recover its homeostasis being a global response of the whole body, evolutionarily preserved against macro and microscopic injuries. The development and progression of chronic diseases or conditions, particularly chronic stress, closely related to low-grade or subclinical inflammations induced by several aggressors (physical, environmental or psychological) will be discussed. The cross-talk among basic cellular and molecular aspects of inflammation, the local and systemic immune processes regulating pro- and anti-inflammatory molecules of innate and acquired immunity will be analyzed as well it will be the interconnected feedback among neuronal pathways, their encephalic nuclei and endocrine responses in healthy conditions. The systemic alterations that develop in these systems when occurs a sustained aggression by chronic stress will be pointed out. It is concluded that the professionals who are members of the health team must work together and guide adults in order to educate their children to acquire healthy lifestyle habits that may avoid, prevent and alleviate the condition of chronic inflammation and stress. Se revisará cómo se inicia la típica cascada de la inflamación y se enfatizará que la misma conforma la “vía final común” normal del organismo para recuperar su homeoestásis saludable, siendo la inflamación una respuesta global de todo el cuerpo, evolutivamente preservada ante injurias macro- y microscópicas. Se mencionará que el desarrollo y la progresión de enfermedades o condiciones crónicas, en particular el estrés crónico, están relacionadas con la inflamación de bajo grado o subclínica, sean las circunstancias y los agentes agresores de naturaleza física, ambiental, emocional o psicológico. Se revisarán los aspectos básicos a nivel celular y molecular de la inflamación, los procesos inmunes locales y sistémicos de regulación de moléculas pro- y antiinflamatoria liberados por las poblaciones celulares que integran los Sistemas Inmune Innato y Adquirido. Se señalarán los nexos interconectados y de retroalimentación de determinadas vías neuronales, sus núcleos encefálicos y sus respuestas endócrinas en condiciones de salud. Luego, se describirán las alteraciones sistémicas que se desarrollan en estos complejos sistemas interconectados ante la agresión sostenida inducida por el estrés crónico. Concluyendo así que los profesionales integrantes del equipo de salud deberían trabajar de modo integrado para guiar a los adultos y éstos educar a sus hijos, para adquirir hábitos de vida saludables que eviten y alivien la condición de inflamación crónica y el estrés. Será revisto como começa a cascata típica de inflamação e será enfatizado que ela forma a "via comum final" normal para o organismo recuperar sua homeostase saudável, sendo a inflamação uma resposta global de todo o corpo, evolutivamente preservada contra lesões macro- e microscópicas. Será mencionado que o desenvolvimento e a progressão de doenças ou condições crônicas, em particular o estresse crônico, estão relacionados à inflamação de baixo grau ou subclínica, independentemente das circunstâncias e dos agentes agressores de natureza física, ambiental, emocional ou psicológica. Serão revisados os aspectos básicos no nível celular e molecular da inflamação, os processos imunológicos locais e sistêmicos de regulação de moléculas pró e anti-inflamatórias liberadas pelas populações de células que compõem os Sistemas Imunológicos Inatos e Adquiridos. Serão apontados os links interconectados e de feedback de certas vias neurais, seus núcleos encefálicos e suas respostas endócrinas em condições saudáveis. Em seguida, serão descritas as alterações sistêmicas que se desenvolvem nesses sistemas complexos interconectados em fase da agressão sustentada induzida por estresse crônico. Concluindo assim que os profissionais que integram a equipe de saúde devem atuar de forma integrada para orientar os adultos e educar seus filhos, adquirir hábitos de vida saudáveis que evitem e aliviem o quadro de inflamação crônica e estresse. Asociación de Medicina del Estrés y Psicoinmunoneuroendocrinología 2021-12-27 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf text/html https://revistas.unc.edu.ar/index.php/pinelatam/article/view/35444 ark:/s27968677/eo6x2ps5j Pinelatinoamericana; Vol. 1 No. 1 (2021); 3-11 Pinelatinoamericana; Vol. 1 Núm. 1 (2021); 3-11 Pinelatinoamericana; V. 1 N. 1 (2021); 3-11 Pinelatinoamericana; v. 1 n. 1 (2021); 3-11 2796-8677 spa https://revistas.unc.edu.ar/index.php/pinelatam/article/view/35444/36408 https://revistas.unc.edu.ar/index.php/pinelatam/article/view/35444/35577 Derechos de autor 2021 Pinelatinoamericana https://creativecommons.org/licenses/by-nc/4.0

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