Fine-scale genomic analyses of admixed individuals reveal unrecognized genetic ancestry components in Argentina

Mostrar todas las versiones(3)

Similarly to other populations across the Americas, Argentinean populations trace back their genetic ancestry into African, European and Native American ancestors, reflecting a complex demographic history with multiple migration and admixture events in pre- and post-colonial times. However, little i...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Luisi, Pierre, García, Angelina, Berros, Juan Manuel, Motti, Josefina María Brenda, Demarchi, Dario, Alfaro Gómez, Emma Laura, Aquilano, Eliana Anahi, Argüelles, Carina Francisca, Avena, Sergio Alejandro, Bailliet, Graciela, Beltramo, Julieta, Bravi, Claudio Marcelo, Cuello, Mariela Vanesa, Dejean, Cristina Beatriz, Dipierri, Jose Edgardo, Jurado Medina, Laura Smeldy, Lanata, Jose Luis, Muzzio, Marina, Parolin, María Laura, Pauro, Maia, Paz Sepúlveda, Paula Beatriz, Rodríguez Golpe, Daniela Carmen, Santos, María Rita, Schwab, Marisol Elisabet, Silvero, Natalia, Zubrzycki, Jeremías Enrique, Ramallo, Virginia, Dopazo, Hernán Javier
Formato: Artículo publishedVersion
Lenguaje:Inglés
Publicado: Public Library of Science 2020
Materias:
Ancestry
Native American
Argentina
Genética y Herencia
Ciencias Biológicas
CIENCIAS NATURALES Y EXACTAS
Acceso en línea:http://hdl.handle.net/11336/128640
http://suquia.ffyh.unc.edu.ar/handle/11336/128640
Aporte de:
Suquía - Instituto de Antropología de Córdoba (IDACOR, CONICET y UNC) de Universidad Nacional de Córdoba
id I10-R181-11336-128640
record_format dspace
institution Universidad Nacional de Córdoba
institution_str I-10
repository_str R-181
collection Suquía - Instituto de Antropología de Córdoba (IDACOR, CONICET y UNC)
language Inglés
topic Ancestry
Native American
Argentina
Genética y Herencia
Ciencias Biológicas
CIENCIAS NATURALES Y EXACTAS
spellingShingle Ancestry
Native American
Argentina
Genética y Herencia
Ciencias Biológicas
CIENCIAS NATURALES Y EXACTAS
Luisi, Pierre
García, Angelina
Berros, Juan Manuel
Motti, Josefina María Brenda
Demarchi, Dario
Alfaro Gómez, Emma Laura
Aquilano, Eliana Anahi
Argüelles, Carina Francisca
Avena, Sergio Alejandro
Bailliet, Graciela
Beltramo, Julieta
Bravi, Claudio Marcelo
Cuello, Mariela Vanesa
Dejean, Cristina Beatriz
Dipierri, Jose Edgardo
Jurado Medina, Laura Smeldy
Lanata, Jose Luis
Muzzio, Marina
Parolin, María Laura
Pauro, Maia
Paz Sepúlveda, Paula Beatriz
Rodríguez Golpe, Daniela Carmen
Santos, María Rita
Schwab, Marisol Elisabet
Silvero, Natalia
Zubrzycki, Jeremías Enrique
Ramallo, Virginia
Dopazo, Hernán Javier
Fine-scale genomic analyses of admixed individuals reveal unrecognized genetic ancestry components in Argentina
topic_facet Ancestry
Native American
Argentina
Genética y Herencia
Ciencias Biológicas
CIENCIAS NATURALES Y EXACTAS
description Similarly to other populations across the Americas, Argentinean populations trace back their genetic ancestry into African, European and Native American ancestors, reflecting a complex demographic history with multiple migration and admixture events in pre- and post-colonial times. However, little is known about the sub-continental origins of these three main ancestries. We present new high-throughput genotyping data for 87 admixed individuals across Argentina. This data was combined to previously published data for admixed individuals in the region and then compared to different reference panels specifically built to perform population structure analyses at a sub-continental level. Concerning the Native American ancestry, we could identify four Native American components segregating in modern Argentinean populations. Three of them are also found in modern South American populations and are specifically represented in Central Andes, Central Chile/Patagonia, and Subtropical and Tropical Forests geographic areas. The fourth component might be specific to the Central Western region of Argentina, and it is not well represented in any genomic data from the literature. As for the European and African ancestries, we confirmed previous results about origins from Southern Europe, Western and Central Western Africa, and we provide evidences for the presence of Northern European and Eastern African ancestries.
format Artículo
Artículo
publishedVersion
author Luisi, Pierre
García, Angelina
Berros, Juan Manuel
Motti, Josefina María Brenda
Demarchi, Dario
Alfaro Gómez, Emma Laura
Aquilano, Eliana Anahi
Argüelles, Carina Francisca
Avena, Sergio Alejandro
Bailliet, Graciela
Beltramo, Julieta
Bravi, Claudio Marcelo
Cuello, Mariela Vanesa
Dejean, Cristina Beatriz
Dipierri, Jose Edgardo
Jurado Medina, Laura Smeldy
Lanata, Jose Luis
Muzzio, Marina
Parolin, María Laura
Pauro, Maia
Paz Sepúlveda, Paula Beatriz
Rodríguez Golpe, Daniela Carmen
Santos, María Rita
Schwab, Marisol Elisabet
Silvero, Natalia
Zubrzycki, Jeremías Enrique
Ramallo, Virginia
Dopazo, Hernán Javier
author_facet Luisi, Pierre
García, Angelina
Berros, Juan Manuel
Motti, Josefina María Brenda
Demarchi, Dario
Alfaro Gómez, Emma Laura
Aquilano, Eliana Anahi
Argüelles, Carina Francisca
Avena, Sergio Alejandro
Bailliet, Graciela
Beltramo, Julieta
Bravi, Claudio Marcelo
Cuello, Mariela Vanesa
Dejean, Cristina Beatriz
Dipierri, Jose Edgardo
Jurado Medina, Laura Smeldy
Lanata, Jose Luis
Muzzio, Marina
Parolin, María Laura
Pauro, Maia
Paz Sepúlveda, Paula Beatriz
Rodríguez Golpe, Daniela Carmen
Santos, María Rita
Schwab, Marisol Elisabet
Silvero, Natalia
Zubrzycki, Jeremías Enrique
Ramallo, Virginia
Dopazo, Hernán Javier
author_sort Luisi, Pierre
title Fine-scale genomic analyses of admixed individuals reveal unrecognized genetic ancestry components in Argentina
title_short Fine-scale genomic analyses of admixed individuals reveal unrecognized genetic ancestry components in Argentina
title_full Fine-scale genomic analyses of admixed individuals reveal unrecognized genetic ancestry components in Argentina
title_fullStr Fine-scale genomic analyses of admixed individuals reveal unrecognized genetic ancestry components in Argentina
title_full_unstemmed Fine-scale genomic analyses of admixed individuals reveal unrecognized genetic ancestry components in Argentina
title_sort fine-scale genomic analyses of admixed individuals reveal unrecognized genetic ancestry components in argentina
publisher Public Library of Science
publishDate 2020
url http://hdl.handle.net/11336/128640
http://suquia.ffyh.unc.edu.ar/handle/11336/128640
work_keys_str_mv AT luisipierre finescalegenomicanalysesofadmixedindividualsrevealunrecognizedgeneticancestrycomponentsinargentina
AT garciaangelina finescalegenomicanalysesofadmixedindividualsrevealunrecognizedgeneticancestrycomponentsinargentina
AT berrosjuanmanuel finescalegenomicanalysesofadmixedindividualsrevealunrecognizedgeneticancestrycomponentsinargentina
AT mottijosefinamariabrenda finescalegenomicanalysesofadmixedindividualsrevealunrecognizedgeneticancestrycomponentsinargentina
AT demarchidario finescalegenomicanalysesofadmixedindividualsrevealunrecognizedgeneticancestrycomponentsinargentina
AT alfarogomezemmalaura finescalegenomicanalysesofadmixedindividualsrevealunrecognizedgeneticancestrycomponentsinargentina
AT aquilanoelianaanahi finescalegenomicanalysesofadmixedindividualsrevealunrecognizedgeneticancestrycomponentsinargentina
AT arguellescarinafrancisca finescalegenomicanalysesofadmixedindividualsrevealunrecognizedgeneticancestrycomponentsinargentina
AT avenasergioalejandro finescalegenomicanalysesofadmixedindividualsrevealunrecognizedgeneticancestrycomponentsinargentina
AT baillietgraciela finescalegenomicanalysesofadmixedindividualsrevealunrecognizedgeneticancestrycomponentsinargentina
AT beltramojulieta finescalegenomicanalysesofadmixedindividualsrevealunrecognizedgeneticancestrycomponentsinargentina
AT braviclaudiomarcelo finescalegenomicanalysesofadmixedindividualsrevealunrecognizedgeneticancestrycomponentsinargentina
AT cuellomarielavanesa finescalegenomicanalysesofadmixedindividualsrevealunrecognizedgeneticancestrycomponentsinargentina
AT dejeancristinabeatriz finescalegenomicanalysesofadmixedindividualsrevealunrecognizedgeneticancestrycomponentsinargentina
AT dipierrijoseedgardo finescalegenomicanalysesofadmixedindividualsrevealunrecognizedgeneticancestrycomponentsinargentina
AT juradomedinalaurasmeldy finescalegenomicanalysesofadmixedindividualsrevealunrecognizedgeneticancestrycomponentsinargentina
AT lanatajoseluis finescalegenomicanalysesofadmixedindividualsrevealunrecognizedgeneticancestrycomponentsinargentina
AT muzziomarina finescalegenomicanalysesofadmixedindividualsrevealunrecognizedgeneticancestrycomponentsinargentina
AT parolinmarialaura finescalegenomicanalysesofadmixedindividualsrevealunrecognizedgeneticancestrycomponentsinargentina
AT pauromaia finescalegenomicanalysesofadmixedindividualsrevealunrecognizedgeneticancestrycomponentsinargentina
AT pazsepulvedapaulabeatriz finescalegenomicanalysesofadmixedindividualsrevealunrecognizedgeneticancestrycomponentsinargentina
AT rodriguezgolpedanielacarmen finescalegenomicanalysesofadmixedindividualsrevealunrecognizedgeneticancestrycomponentsinargentina
AT santosmariarita finescalegenomicanalysesofadmixedindividualsrevealunrecognizedgeneticancestrycomponentsinargentina
AT schwabmarisolelisabet finescalegenomicanalysesofadmixedindividualsrevealunrecognizedgeneticancestrycomponentsinargentina
AT silveronatalia finescalegenomicanalysesofadmixedindividualsrevealunrecognizedgeneticancestrycomponentsinargentina
AT zubrzyckijeremiasenrique finescalegenomicanalysesofadmixedindividualsrevealunrecognizedgeneticancestrycomponentsinargentina
AT ramallovirginia finescalegenomicanalysesofadmixedindividualsrevealunrecognizedgeneticancestrycomponentsinargentina
AT dopazohernanjavier finescalegenomicanalysesofadmixedindividualsrevealunrecognizedgeneticancestrycomponentsinargentina
bdutipo_str Repositorios
_version_ 1764820397514031105

Ejemplares similares