High interpopulation homogeneity in Central Argentina as assessed by Ancestry Informative Markers (AIMs)

The population of Argentina has already been studied with regard to several genetic markers, but much more data are needed for the appropriate definition of its genetic profile. This study aimed at investigating the admixture patterns and genetic structure in Central Argentina, using biparental mark...

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Autores principales: García, Angelina, Demarchi, Dario, Tovo Rodrigues, Luciana, Pauro, Maia, Callegari Jacques, Sidia M., Salzano, Francisco M., Hutz, Mara H.
Formato: Artículo publishedVersion
Lenguaje:Inglés
Publicado: Sociedade Brasileira de Genética 2015
Materias:
Acceso en línea:http://hdl.handle.net/11336/11103
http://suquia.ffyh.unc.edu.ar/handle/11336/11103
Aporte de:
id I10-R181-11336-11103
record_format dspace
institution Universidad Nacional de Córdoba
institution_str I-10
repository_str R-181
collection Suquía - Instituto de Antropología de Córdoba (IDACOR, CONICET y UNC)
language Inglés
topic AIMs
CÓRDOBA
MIGRATIONS
POPULATION STRUCTURE
SAN LUIS
Otras Humanidades
Otras Humanidades
HUMANIDADES
Otras Humanidades
Otras Humanidades
HUMANIDADES
spellingShingle AIMs
CÓRDOBA
MIGRATIONS
POPULATION STRUCTURE
SAN LUIS
Otras Humanidades
Otras Humanidades
HUMANIDADES
Otras Humanidades
Otras Humanidades
HUMANIDADES
García, Angelina
Demarchi, Dario
Tovo Rodrigues, Luciana
Pauro, Maia
Callegari Jacques, Sidia M.
Salzano, Francisco M.
Hutz, Mara H.
High interpopulation homogeneity in Central Argentina as assessed by Ancestry Informative Markers (AIMs)
topic_facet AIMs
CÓRDOBA
MIGRATIONS
POPULATION STRUCTURE
SAN LUIS
Otras Humanidades
Otras Humanidades
HUMANIDADES
Otras Humanidades
Otras Humanidades
HUMANIDADES
description The population of Argentina has already been studied with regard to several genetic markers, but much more data are needed for the appropriate definition of its genetic profile. This study aimed at investigating the admixture patterns and genetic structure in Central Argentina, using biparental markers and comparing the results with those previously obtained by us with mitochondrial DNA (mtDNA) in the same samples. A total of 521 healthy unrelated individuals living in 13 villages of the Córdoba and San Luis provinces were tested. The individuals were genotyped for ten autosomal ancestry informative markers (AIMs). Allele frequencies were compared with those of African, European and Native American populations, chosen to represent parental contributions. The AIM estimates indicated a greater influence of the Native American ancestry as compared to previous studies in the same or other Argentinean regions, but smaller than that observed with the mtDNA tests. These differences can be explained, respectively, by different genetic contributions between rural and urban areas, and asymmetric gene flow occurred in the past. But a most unexpected finding was the marked interpopulation genetic homogeneity found in villages located in diverse geographic environments across a wide territory, suggesting considerable gene flow.
format Artículo
Artículo
publishedVersion
author García, Angelina
Demarchi, Dario
Tovo Rodrigues, Luciana
Pauro, Maia
Callegari Jacques, Sidia M.
Salzano, Francisco M.
Hutz, Mara H.
author_facet García, Angelina
Demarchi, Dario
Tovo Rodrigues, Luciana
Pauro, Maia
Callegari Jacques, Sidia M.
Salzano, Francisco M.
Hutz, Mara H.
author_sort García, Angelina
title High interpopulation homogeneity in Central Argentina as assessed by Ancestry Informative Markers (AIMs)
title_short High interpopulation homogeneity in Central Argentina as assessed by Ancestry Informative Markers (AIMs)
title_full High interpopulation homogeneity in Central Argentina as assessed by Ancestry Informative Markers (AIMs)
title_fullStr High interpopulation homogeneity in Central Argentina as assessed by Ancestry Informative Markers (AIMs)
title_full_unstemmed High interpopulation homogeneity in Central Argentina as assessed by Ancestry Informative Markers (AIMs)
title_sort high interpopulation homogeneity in central argentina as assessed by ancestry informative markers (aims)
publisher Sociedade Brasileira de Genética
publishDate 2015
url http://hdl.handle.net/11336/11103
http://suquia.ffyh.unc.edu.ar/handle/11336/11103
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