From genetic alterations to new molecular targets in pituitary disorders

3.9 Impact Factor

Detalles Bibliográficos
Autores principales: Ferraris, Jimena, Perez Millan, María Inés, Petiti, Juan Pablo
Otros Autores: https://orcid.org/0000-0001-7472-0439
Formato: publishedVersion article
Lenguaje:Inglés
Publicado: 2024
Materias:
Pituitary plasticity
Pituitary tumors
Wnt/b-catenin pathway
Sphingosine-1phosphate
Low blood testosterone level
Acceso en línea:http://hdl.handle.net/11086/552688
https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2024.1375475/full
https://doi.org/10.3389/fendo.2024.1375475
Aporte de:
Repositorio Digital Universitario (UNC) de Universidad Nacional de Córdoba
id I10-R141-11086-552688
record_format dspace
spelling I10-R141-11086-5526882024-07-12T06:20:55Z From genetic alterations to new molecular targets in pituitary disorders Ferraris, Jimena Perez Millan, María Inés Petiti, Juan Pablo https://orcid.org/0000-0001-7472-0439 https://orcid.org/0000-0002-0486-109X https://orcid.org/0000-0002-8555-3426 Pituitary plasticity Pituitary tumors Wnt/b-catenin pathway Sphingosine-1phosphate Low blood testosterone level 3.9 Impact Factor info:eu-repo/semantics/publishedVersion Fil: Ferraris, Jimena. Stockholm University. Department of Biophysics and Biochemistry; Suecia. Fil: Pérez Millan, María Inés. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Biociencia, Biotecnología y Biología Traslacional. Departamento de Fisiología, Biología Molecular y Celular; Argentina. Fil: Petiti, Juan Pablo. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Centro de Microscopía Electrónica; Argentina. Fil: Petiti, Juan Pablo. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ciencias de la Salud; Argentina. The pituitary gland is a central regulator of growth, reproduction and stress among other physiological functions through the secretion of five different hormone-producing cells types. A main characteristic of the anterior pituitary gland is its plasticity, which allows to adjust to different physiological conditions related to endocrine demands. Hormones are secreted by specific cells in the pituitary gland and this secretion is pulsatile (1). Pulses of pituitary hormones are generated and modified at multiple levels. From a therapeutic point of view, efforts are being focused on the study of normal hypothalamic-pituitary axes function and how dysregulation occurs in a disease context. This is particularly relevant to pituitary tumors, where hormone output is largely independent of hypothalamic stimulation (2). info:eu-repo/semantics/publishedVersion Fil: Ferraris, Jimena. Stockholm University. Department of Biophysics and Biochemistry; Suecia. Fil: Pérez Millan, María Inés. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Biociencia, Biotecnología y Biología Traslacional. Departamento de Fisiología, Biología Molecular y Celular; Argentina. Fil: Petiti, Juan Pablo. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Centro de Microscopía Electrónica; Argentina. Fil: Petiti, Juan Pablo. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ciencias de la Salud; Argentina. 2024-07-11T17:24:38Z 2024-07-11T17:24:38Z 2024-02-07 article Ferraris J, Perez-Millan MI and Petiti JP (2024) Editorial: From genetic alterations to new molecular targets in pituitary disorders. Front. Endocrinol. 15:1375475. doi: 10.3389/fendo.2024.1375475 1664-2392 http://hdl.handle.net/11086/552688 https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2024.1375475/full https://doi.org/10.3389/fendo.2024.1375475 eng Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/
institution Universidad Nacional de Córdoba
institution_str I-10
repository_str R-141
collection Repositorio Digital Universitario (UNC)
language Inglés
topic Pituitary plasticity
Pituitary tumors
Wnt/b-catenin pathway
Sphingosine-1phosphate
Low blood testosterone level
spellingShingle Pituitary plasticity
Pituitary tumors
Wnt/b-catenin pathway
Sphingosine-1phosphate
Low blood testosterone level
Ferraris, Jimena
Perez Millan, María Inés
Petiti, Juan Pablo
From genetic alterations to new molecular targets in pituitary disorders
topic_facet Pituitary plasticity
Pituitary tumors
Wnt/b-catenin pathway
Sphingosine-1phosphate
Low blood testosterone level
description 3.9 Impact Factor
author2 https://orcid.org/0000-0001-7472-0439
author_facet https://orcid.org/0000-0001-7472-0439
Ferraris, Jimena
Perez Millan, María Inés
Petiti, Juan Pablo
format publishedVersion
article
author Ferraris, Jimena
Perez Millan, María Inés
Petiti, Juan Pablo
author_sort Ferraris, Jimena
title From genetic alterations to new molecular targets in pituitary disorders
title_short From genetic alterations to new molecular targets in pituitary disorders
title_full From genetic alterations to new molecular targets in pituitary disorders
title_fullStr From genetic alterations to new molecular targets in pituitary disorders
title_full_unstemmed From genetic alterations to new molecular targets in pituitary disorders
title_sort from genetic alterations to new molecular targets in pituitary disorders
publishDate 2024
url http://hdl.handle.net/11086/552688
https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2024.1375475/full
https://doi.org/10.3389/fendo.2024.1375475
work_keys_str_mv AT ferrarisjimena fromgeneticalterationstonewmoleculartargetsinpituitarydisorders
AT perezmillanmariaines fromgeneticalterationstonewmoleculartargetsinpituitarydisorders
AT petitijuanpablo fromgeneticalterationstonewmoleculartargetsinpituitarydisorders
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