Kinetic study of the stereoselectivity reduction of acetophenone promoted by a strain of Geotrichum spp

Fil: Decarlini, M. F. Universidad Católica de Córdoba. Facultad de Ciencias Químicas; Argentina.

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Detalles Bibliográficos
Autores principales: Decarlini, M. F., Vázquez, A. M., Aimar, M. L.
Formato: conferenceObject
Lenguaje:Inglés
Publicado: 2024
Materias:
Biocatalysis
Bioreduction
Prochiral ketones
Ciencias Químicas
Química Aplicada
Acceso en línea:http://hdl.handle.net/11086/550480
Aporte de:
Repositorio Digital Universitario (UNC) de Universidad Nacional de Córdoba
id I10-R141-11086-550480
record_format dspace
spelling I10-R141-11086-5504802024-02-15T13:48:16Z Kinetic study of the stereoselectivity reduction of acetophenone promoted by a strain of Geotrichum spp Decarlini, M. F. Vázquez, A. M. Aimar, M. L. Biocatalysis Bioreduction Prochiral ketones Ciencias Químicas Química Aplicada Fil: Decarlini, M. F. Universidad Católica de Córdoba. Facultad de Ciencias Químicas; Argentina. Fil: Vázquez, A. M. Universidad Católica de Córdoba. Facultad de Ciencias Químicas; Argentina. Fil: Aimar, M. L. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales. Departamento de Química. Cátedra de Química Aplicada; Argentina. Nowadays, biocatalytic stereoselective reduction of prochiral ketones is one of the most important methodologies in organic synthesis for the preparation of chiral alcohols. These enantiomerically pure alcohols are very important because they are key precursors in the obtaining of pharmaceutical compounds. Recently, a screening on fifty six strains of bacteria and fungi was made for our team toidentify microorganisms capable of performing the stereoselective reduction of acetophenone (AP) to 1-phenylethanol (1-PE). From this study a strain of Geotrichum spp.has been isolated and characterized, and this yeast has presented anexcellent conversion (>99%) and stereoselectivity (>99.9 e.e.%) in the preparation of (R)-1-PE from AP. Fil: Decarlini, M. F. Universidad Católica de Córdoba. Facultad de Ciencias Químicas; Argentina. Fil: Vázquez, A. M. Universidad Católica de Córdoba. Facultad de Ciencias Químicas; Argentina. Fil: Aimar, M. L. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales. Departamento de Química. Cátedra de Química Aplicada; Argentina. Otras Ciencias Químicas 2024-02-14T12:00:23Z 2024-02-14T12:00:23Z 2015 conferenceObject http://hdl.handle.net/11086/550480 eng Attribution-NonCommercial-ShareAlike 4.0 International http://creativecommons.org/licenses/by-nc-sa/4.0/ Impreso
institution Universidad Nacional de Córdoba
institution_str I-10
repository_str R-141
collection Repositorio Digital Universitario (UNC)
language Inglés
topic Biocatalysis
Bioreduction
Prochiral ketones
Ciencias Químicas
Química Aplicada
spellingShingle Biocatalysis
Bioreduction
Prochiral ketones
Ciencias Químicas
Química Aplicada
Decarlini, M. F.
Vázquez, A. M.
Aimar, M. L.
Kinetic study of the stereoselectivity reduction of acetophenone promoted by a strain of Geotrichum spp
topic_facet Biocatalysis
Bioreduction
Prochiral ketones
Ciencias Químicas
Química Aplicada
description Fil: Decarlini, M. F. Universidad Católica de Córdoba. Facultad de Ciencias Químicas; Argentina.
format conferenceObject
author Decarlini, M. F.
Vázquez, A. M.
Aimar, M. L.
author_facet Decarlini, M. F.
Vázquez, A. M.
Aimar, M. L.
author_sort Decarlini, M. F.
title Kinetic study of the stereoselectivity reduction of acetophenone promoted by a strain of Geotrichum spp
title_short Kinetic study of the stereoselectivity reduction of acetophenone promoted by a strain of Geotrichum spp
title_full Kinetic study of the stereoselectivity reduction of acetophenone promoted by a strain of Geotrichum spp
title_fullStr Kinetic study of the stereoselectivity reduction of acetophenone promoted by a strain of Geotrichum spp
title_full_unstemmed Kinetic study of the stereoselectivity reduction of acetophenone promoted by a strain of Geotrichum spp
title_sort kinetic study of the stereoselectivity reduction of acetophenone promoted by a strain of geotrichum spp
publishDate 2024
url http://hdl.handle.net/11086/550480
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AT vazquezam kineticstudyofthestereoselectivityreductionofacetophenonepromotedbyastrainofgeotrichumspp
AT aimarml kineticstudyofthestereoselectivityreductionofacetophenonepromotedbyastrainofgeotrichumspp
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