Effect of sodium fluoride or sodium monofluorphosphate treatment in an alveolar bone healing experimental model

Fil: Romanazzi Chumbita, Lucas. Universidad Nacional de Córdoba. Facultad de Odontología. Cátedra Química Biológica A; Argentina.

Detalles Bibliográficos
Autores principales: Romanazzi Chumbita, Lucas, Reati, Carolina, Fontanetti, Pablo Alejandro, Interlandi, Victoria, Centeno, Viviana Andrea
Formato: conferenceObject
Lenguaje:Inglés
Publicado: 2023
Materias:
Monofluorphosfate
Acceso en línea:http://hdl.handle.net/11086/548375
Aporte de:
Repositorio Digital Universitario (UNC) de Universidad Nacional de Córdoba
id I10-R141-11086-548375
record_format dspace
spelling I10-R141-11086-5483752024-07-02T18:28:13Z Effect of sodium fluoride or sodium monofluorphosphate treatment in an alveolar bone healing experimental model Romanazzi Chumbita, Lucas Reati, Carolina Fontanetti, Pablo Alejandro Interlandi, Victoria Centeno, Viviana Andrea Monofluorphosfate Fil: Romanazzi Chumbita, Lucas. Universidad Nacional de Córdoba. Facultad de Odontología. Cátedra Química Biológica A; Argentina. Fil: Reati, Carolina. Universidad Nacional de Córdoba. Facultad de Odontología. Cátedra Química Biológica A; Argentina. Fil: Fontanetti, Pablo Alejandro. Universidad Nacional de Córdoba. Facultad de Odontología. Cátedra Introducción a la Química y Física Biológicas A; Argentina. Fil: Interlandi, Victoria. Universidad Nacional de Córdoba. Facultad de Odontología. Cátedra Química Biológica A; Argentina. Fil: Centeno, Viviana Andrea. Universidad Nacional de Córdoba. Facultad de Odontología. Cátedra Química Biológica A; Argentina. Depending on the dose and the way of administration, fluoride (F-) produces different physico-chemicals and biological effects on bone tissue. The F- biodisponibility is higher when it is administrated as sodium monofluorphosphate (MFP) compared to sodium fluoride (NaF) at equivalent doses. OBJECTIVE: to compare the effect produced by F- administratio n in the form of NaF or MFP, post first molar extraction, on biochemicals markers of phosphocalcic metabolism and morphometric parameters of mandibular growth. METHODS: the first right lower molar of twelve 21-days-old male Wistar rats was extracted under anesthesia. Then, rats were divided into three experimental groups which received distilled water (control) or a solution containing 80 mmol of NaF or MFP per day during 21 days. The treatment was administrated by orogastric catheter. After treatment, animals were euthanized by cervical dislocation and mandibles were collected. Plasma Ca and P levels and alkaline phosphatase (ALP) activity were determined. Morphometric parameters of mandible growth were measured on digital radiographic images using the software Romexis. Data were analyzed by ANOVA and Bonferroni?s post hoc test. RESULTS: Phosphatemia increased in animals under F- treatment respect control animals (p<0,05); an increase in ALP activity was observed o nly in NaF group compared to control (p<0,05). The F- treatment, d! id not affect mandible growth parameters. CONCLUSIONS: the administration of F-, as NaF or MFP, by orogastric catheter after first molar extraction, affected some plasma markers related with phosphocalcic metabolism, effect more pronounced in NaF group. Fil: Romanazzi Chumbita, Lucas. Universidad Nacional de Córdoba. Facultad de Odontología. Cátedra Química Biológica A; Argentina. Fil: Reati, Carolina. Universidad Nacional de Córdoba. Facultad de Odontología. Cátedra Química Biológica A; Argentina. Fil: Fontanetti, Pablo Alejandro. Universidad Nacional de Córdoba. Facultad de Odontología. Cátedra Introducción a la Química y Física Biológicas A; Argentina. Fil: Interlandi, Victoria. Universidad Nacional de Córdoba. Facultad de Odontología. Cátedra Química Biológica A; Argentina. Fil: Centeno, Viviana Andrea. Universidad Nacional de Córdoba. Facultad de Odontología. Cátedra Química Biológica A; Argentina. Otras Ciencias de la Salud 2023-08-07T14:06:29Z 2023-08-07T14:06:29Z 2016 conferenceObject http://hdl.handle.net/11086/548375 eng Attribution-NonCommercial-ShareAlike 4.0 International http://creativecommons.org/licenses/by-nc-sa/4.0/ Impreso
institution Universidad Nacional de Córdoba
institution_str I-10
repository_str R-141
collection Repositorio Digital Universitario (UNC)
language Inglés
topic Monofluorphosfate
spellingShingle Monofluorphosfate
Romanazzi Chumbita, Lucas
Reati, Carolina
Fontanetti, Pablo Alejandro
Interlandi, Victoria
Centeno, Viviana Andrea
Effect of sodium fluoride or sodium monofluorphosphate treatment in an alveolar bone healing experimental model
topic_facet Monofluorphosfate
description Fil: Romanazzi Chumbita, Lucas. Universidad Nacional de Córdoba. Facultad de Odontología. Cátedra Química Biológica A; Argentina.
format conferenceObject
author Romanazzi Chumbita, Lucas
Reati, Carolina
Fontanetti, Pablo Alejandro
Interlandi, Victoria
Centeno, Viviana Andrea
author_facet Romanazzi Chumbita, Lucas
Reati, Carolina
Fontanetti, Pablo Alejandro
Interlandi, Victoria
Centeno, Viviana Andrea
author_sort Romanazzi Chumbita, Lucas
title Effect of sodium fluoride or sodium monofluorphosphate treatment in an alveolar bone healing experimental model
title_short Effect of sodium fluoride or sodium monofluorphosphate treatment in an alveolar bone healing experimental model
title_full Effect of sodium fluoride or sodium monofluorphosphate treatment in an alveolar bone healing experimental model
title_fullStr Effect of sodium fluoride or sodium monofluorphosphate treatment in an alveolar bone healing experimental model
title_full_unstemmed Effect of sodium fluoride or sodium monofluorphosphate treatment in an alveolar bone healing experimental model
title_sort effect of sodium fluoride or sodium monofluorphosphate treatment in an alveolar bone healing experimental model
publishDate 2023
url http://hdl.handle.net/11086/548375
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