Activation of erk1/2 and axogenesis induced by estradiol depend on different calcium pools in male rat hypothalamic neurons in vitro

Fil: Cabrera Zapata, Lucas Ezequiel. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina.

Detalles Bibliográficos
Autores principales: Cabrera Zapata, Lucas Ezequiel, Cambiasso, María Julia
Formato: conferenceObject
Lenguaje:Inglés
Publicado: 2023
Materias:
Estradiol
Calcium
Hypothalamic Diseases
Acceso en línea:http://hdl.handle.net/11086/547807
Aporte de:
Repositorio Digital Universitario (UNC) de Universidad Nacional de Córdoba
id I10-R141-11086-547807
record_format dspace
spelling I10-R141-11086-5478072024-07-02T18:28:12Z Activation of erk1/2 and axogenesis induced by estradiol depend on different calcium pools in male rat hypothalamic neurons in vitro Cabrera Zapata, Lucas Ezequiel Cambiasso, María Julia Estradiol Calcium Hypothalamic Diseases Fil: Cabrera Zapata, Lucas Ezequiel. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina. Fil: Cabrera Zapata, Lucas Ezequiel. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales; Argentina. Fil: Cambiasso, María Julia. Universidad Nacional de Córdoba. Facultad de Odontología. Cátedra de Biología Celular B; Argentina. Fil: Cambiasso, María Julia. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina. Estrogens generate a wide diversity of rapid “non-classical” effects which occur in a range from some seconds to few minutes (Arevalo et al., 2012), including the triggering of Ca2+ signals (Wong et al., 2012) and the activation of several signaling pathways such as the protein kinase C (PKC) and the extracellular signal-regulated kinase 1 and 2 (ERK1/2) cascades (Wu et al., 2005). Previous studies from our laboratory have shown that 17β-estradiol (E2) induces axonal growth through ERK1/2 activation in hypothalamic neurons of male embryos of 16 days of gestation (E16; Gorosito & Cambiasso, 2008). Both axogenesis and ERK1/2 activation mediated by the hormone depend on Ca2+ and Ca2+- dependent PKC isoforms (Gorosito & Cambiasso, 2008).In the present study we investigate the Ca2+ pools that participate in the activation of ERK1/2 and axogenesis by E2. http://falan-ibrolarc.org/drupal/es/content/scientific-programme Fil: Cabrera Zapata, Lucas Ezequiel. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina. Fil: Cabrera Zapata, Lucas Ezequiel. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales; Argentina. Fil: Cambiasso, María Julia. Universidad Nacional de Córdoba. Facultad de Odontología. Cátedra de Biología Celular B; Argentina. Fil: Cambiasso, María Julia. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina. Bioquímica y Biología Molecular (ídem 3.1.10) 2023-06-16T12:15:21Z 2023-06-16T12:15:21Z 2016 conferenceObject http://hdl.handle.net/11086/547807 eng Attribution-NonCommercial-ShareAlike 4.0 International http://creativecommons.org/licenses/by-nc-sa/4.0/ Impreso; Electrónico y/o Digital
institution Universidad Nacional de Córdoba
institution_str I-10
repository_str R-141
collection Repositorio Digital Universitario (UNC)
language Inglés
topic Estradiol
Calcium
Hypothalamic Diseases
spellingShingle Estradiol
Calcium
Hypothalamic Diseases
Cabrera Zapata, Lucas Ezequiel
Cambiasso, María Julia
Activation of erk1/2 and axogenesis induced by estradiol depend on different calcium pools in male rat hypothalamic neurons in vitro
topic_facet Estradiol
Calcium
Hypothalamic Diseases
description Fil: Cabrera Zapata, Lucas Ezequiel. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina.
format conferenceObject
author Cabrera Zapata, Lucas Ezequiel
Cambiasso, María Julia
author_facet Cabrera Zapata, Lucas Ezequiel
Cambiasso, María Julia
author_sort Cabrera Zapata, Lucas Ezequiel
title Activation of erk1/2 and axogenesis induced by estradiol depend on different calcium pools in male rat hypothalamic neurons in vitro
title_short Activation of erk1/2 and axogenesis induced by estradiol depend on different calcium pools in male rat hypothalamic neurons in vitro
title_full Activation of erk1/2 and axogenesis induced by estradiol depend on different calcium pools in male rat hypothalamic neurons in vitro
title_fullStr Activation of erk1/2 and axogenesis induced by estradiol depend on different calcium pools in male rat hypothalamic neurons in vitro
title_full_unstemmed Activation of erk1/2 and axogenesis induced by estradiol depend on different calcium pools in male rat hypothalamic neurons in vitro
title_sort activation of erk1/2 and axogenesis induced by estradiol depend on different calcium pools in male rat hypothalamic neurons in vitro
publishDate 2023
url http://hdl.handle.net/11086/547807
work_keys_str_mv AT cabrerazapatalucasezequiel activationoferk12andaxogenesisinducedbyestradioldependondifferentcalciumpoolsinmalerathypothalamicneuronsinvitro
AT cambiassomariajulia activationoferk12andaxogenesisinducedbyestradioldependondifferentcalciumpoolsinmalerathypothalamicneuronsinvitro
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