Update on mechanisms of pituitary tumorigenesis

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Pituitary adenomas are intracranial neoplasms that originate from the adeno-pituitary cells, are mostly benign and slow growing. However, a small percentage can be aggressive and spread locally and / or remotely as malignancies. In recent years, progress has been made in understanding the biology of...

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Detalles Bibliográficos
Autores principales: Cecenarro, Laura Anahi, Moyano Crespo, Gabriela Deisi, Mukdsi, Jorge Humberto
Formato: Artículo revista
Lenguaje:Español
Publicado: Universidad Nacional Cba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2021
Materias:
pituitary
adenoma
carcinogenesis
hipófisis
carcinogénesis
hipófise
carcinogênese
Acceso en línea:https://revistas.unc.edu.ar/index.php/med/article/view/29189
Aporte de:
Revistas de la UNC de Universidad Nacional de Córdoba
id I10-R10article-29189
record_format ojs
institution Universidad Nacional de Córdoba
institution_str I-10
repository_str R-10
container_title_str Revistas de la UNC
language Español
format Artículo revista
topic pituitary
adenoma
carcinogenesis
hipófisis
adenoma
carcinogénesis
hipófise
adenoma
carcinogênese
spellingShingle pituitary
adenoma
carcinogenesis
hipófisis
adenoma
carcinogénesis
hipófise
adenoma
carcinogênese
Cecenarro, Laura Anahi
Moyano Crespo, Gabriela Deisi
Mukdsi, Jorge Humberto
Update on mechanisms of pituitary tumorigenesis
topic_facet pituitary
adenoma
carcinogenesis
hipófisis
adenoma
carcinogénesis
hipófise
adenoma
carcinogênese
author Cecenarro, Laura Anahi
Moyano Crespo, Gabriela Deisi
Mukdsi, Jorge Humberto
author_facet Cecenarro, Laura Anahi
Moyano Crespo, Gabriela Deisi
Mukdsi, Jorge Humberto
author_sort Cecenarro, Laura Anahi
title Update on mechanisms of pituitary tumorigenesis
title_short Update on mechanisms of pituitary tumorigenesis
title_full Update on mechanisms of pituitary tumorigenesis
title_fullStr Update on mechanisms of pituitary tumorigenesis
title_full_unstemmed Update on mechanisms of pituitary tumorigenesis
title_sort update on mechanisms of pituitary tumorigenesis
description Pituitary adenomas are intracranial neoplasms that originate from the adeno-pituitary cells, are mostly benign and slow growing. However, a small percentage can be aggressive and spread locally and / or remotely as malignancies. In recent years, progress has been made in understanding the biology of pituitary tumors, identifying mutations in the germline, somatic lines, and epigenetic mechanisms. Objective: review the updated bibliography on the mechanisms of pituitary tumorigenesis. Data source: bibliographic search was performed using the MEDLINE (PubMed), LILACS and Google Scholar databases since 2010 to April 2020. Conclusion: Knowledge and information on pituitary tumorogenesis mechanisms increased in recent decades, and new neoplastic pathways are recognized. However, there are currently few therapeutic approaches to act specifically on the underlying tumor genesis pathway identified in each case.
publisher Universidad Nacional Cba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
publishDate 2021
url https://revistas.unc.edu.ar/index.php/med/article/view/29189
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