Annual epidemiological study of Human Coronavirus on children interned in the Hospital Infantil Municipal of Córdoba
Human Coronavirus (CoVh) causes respiratory, enteric, cardiovascular diseases and neurological disorders in both humans and animals. In humans it causes cold, rinitis, wheezing, bronchial obstructive syndrome, bronchiolitis, pneumonia and asthma exacerbation in children, adults and immunocompromised...
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| Formato: | Artículo revista |
| Lenguaje: | Español |
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Universidad Nacional Cba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
2019
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| Acceso en línea: | https://revistas.unc.edu.ar/index.php/med/article/view/25774 |
| Aporte de: |
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I10-R10article-25774 |
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ojs |
| institution |
Universidad Nacional de Córdoba |
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I-10 |
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R-10 |
| container_title_str |
Revistas de la UNC |
| language |
Español |
| format |
Artículo revista |
| topic |
human coronavirus epidemiology molecular biology pediatrics córdoba coronavirus humano epidemiologia biología molecular pediatría córdoba |
| spellingShingle |
human coronavirus epidemiology molecular biology pediatrics córdoba coronavirus humano epidemiologia biología molecular pediatría córdoba Liendo, ME Rodríguez, PE Herrera Simó, C Frutos, MC Cuffini, CG Cámara, JA García Oro , MC Cámara, A Annual epidemiological study of Human Coronavirus on children interned in the Hospital Infantil Municipal of Córdoba |
| topic_facet |
human coronavirus epidemiology molecular biology pediatrics córdoba coronavirus humano epidemiologia biología molecular pediatría córdoba |
| author |
Liendo, ME Rodríguez, PE Herrera Simó, C Frutos, MC Cuffini, CG Cámara, JA García Oro , MC Cámara, A |
| author_facet |
Liendo, ME Rodríguez, PE Herrera Simó, C Frutos, MC Cuffini, CG Cámara, JA García Oro , MC Cámara, A |
| author_sort |
Liendo, ME |
| title |
Annual epidemiological study of Human Coronavirus on children interned in the Hospital Infantil Municipal of Córdoba |
| title_short |
Annual epidemiological study of Human Coronavirus on children interned in the Hospital Infantil Municipal of Córdoba |
| title_full |
Annual epidemiological study of Human Coronavirus on children interned in the Hospital Infantil Municipal of Córdoba |
| title_fullStr |
Annual epidemiological study of Human Coronavirus on children interned in the Hospital Infantil Municipal of Córdoba |
| title_full_unstemmed |
Annual epidemiological study of Human Coronavirus on children interned in the Hospital Infantil Municipal of Córdoba |
| title_sort |
annual epidemiological study of human coronavirus on children interned in the hospital infantil municipal of córdoba |
| description |
Human Coronavirus (CoVh) causes respiratory, enteric, cardiovascular diseases and neurological disorders in both humans and animals. In humans it causes cold, rinitis, wheezing, bronchial obstructive syndrome, bronchiolitis, pneumonia and asthma exacerbation in children, adults and immunocompromised. Respiratory CoVhs have gained importance in 2002 and 2012 respectively because of the SARS- CoVh and MERS-CoVh epidemic. In Argentina Maffey (2008) detected prevalence of 2% in patients with respiratory infection. Studies carried out at the Institute of Virology-FCM-UNCórdoba during 2012-2013 reported prevalence of 2 to 3% in the general population, being higher in in-house children. Mano J. in 2018 reported an outbreak of human respiratory infection with Coronavirus, of which 3 out of 20 patients died. This unusual severe viral pathogenesis makes it necessary to continue with your epidemiological surveillance.
The purpose of this study was to detect the annual circulation of CoVh in patients with acute respiratory infection (IRA) by molecular techniques, at the Municipal Children's Hospital (HIM) in Córdoba.
An annual prospective study was conducted from July 2018 to July 2019 . 1,127 samples of nasopharyngeal aspirate and swab from newborn to 14 years old children hospitalized with IRA were analyzed. The technique was molecular biology: one-step RT-PCR. The inclusion criteria was the pediatric IRA-compliant clinic.
Forty-nine of the 1,127 samples tested were positive, giving a prevalence of 4.34% (49/1,127). Prevalences for 30% Respiratory Syncicial Virus, Parainfluenza I 2% Virus, Parainfluenza III Virus 4%, Human Metapneumovirus 4%, Influenza to 4% and bacterial infections enabled a framework of co-infections.
The results highlight the need to continue research on CoVh, as it circulates in the paediatric population of the HIM of Córdoba. The prevalence of 4.34% obtained is in accordance with the one described by several authors and in Cordoba by our group. Clinical diagnosis is insufficient, it is necessary to implement fast and sensitive laboratory molecular diagnosis. This differential viral diagnosis provides knowledge of the epidemiological situation of the region and circulating viral strains, which can influence the severity of cases as reported by Mano J. in 2018 |
| publisher |
Universidad Nacional Cba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología |
| publishDate |
2019 |
| url |
https://revistas.unc.edu.ar/index.php/med/article/view/25774 |
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