Bilateral single sesion whole lung lavage under venous-venous ECMO in a case of severe pulmonary alveolar proteinosis: five years follow up

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Introduction: Pulmonary alveolar proteinosis (PAP) is a rare disease caused by accumulation of proteinaceous material in the alveolar spaces. The most common mechanism implied is the development of antibodies directed to granulocyte macrophage colony stimulating factor (GM-CSF). which inhibits activ...

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Autores principales: Wainstein, Esteban Javier, Las Heras, Marcos, Sinner, Jorge, Kotowicz, Vadim, Precerutti, Juan, San Román, Juan, Svetliza, Graciela
Formato: Artículo revista
Lenguaje:Español
Publicado: Universidad Nacional Cba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2019
Materias:
extracorporeal membrane oxygenation
lung diseases
interstitial
respiratory insufficiency
oxigenación por membrana extracorporea
enfermedades pulmonares intersticiales
insuficiencia respiratoria
Acceso en línea:https://revistas.unc.edu.ar/index.php/med/article/view/22595
Aporte de:
Revistas de la UNC de Universidad Nacional de Córdoba
id I10-R10article-22595
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institution Universidad Nacional de Córdoba
institution_str I-10
repository_str R-10
container_title_str Revistas de la UNC
language Español
format Artículo revista
topic extracorporeal membrane oxygenation
lung diseases
interstitial
respiratory insufficiency
oxigenación por membrana extracorporea
enfermedades pulmonares intersticiales
insuficiencia respiratoria
spellingShingle extracorporeal membrane oxygenation
lung diseases
interstitial
respiratory insufficiency
oxigenación por membrana extracorporea
enfermedades pulmonares intersticiales
insuficiencia respiratoria
Wainstein, Esteban Javier
Las Heras, Marcos
Sinner, Jorge
Kotowicz, Vadim
Precerutti, Juan
San Román, Juan
Svetliza, Graciela
Bilateral single sesion whole lung lavage under venous-venous ECMO in a case of severe pulmonary alveolar proteinosis: five years follow up
topic_facet extracorporeal membrane oxygenation
lung diseases
interstitial
respiratory insufficiency
oxigenación por membrana extracorporea
enfermedades pulmonares intersticiales
insuficiencia respiratoria
author Wainstein, Esteban Javier
Las Heras, Marcos
Sinner, Jorge
Kotowicz, Vadim
Precerutti, Juan
San Román, Juan
Svetliza, Graciela
author_facet Wainstein, Esteban Javier
Las Heras, Marcos
Sinner, Jorge
Kotowicz, Vadim
Precerutti, Juan
San Román, Juan
Svetliza, Graciela
author_sort Wainstein, Esteban Javier
title Bilateral single sesion whole lung lavage under venous-venous ECMO in a case of severe pulmonary alveolar proteinosis: five years follow up
title_short Bilateral single sesion whole lung lavage under venous-venous ECMO in a case of severe pulmonary alveolar proteinosis: five years follow up
title_full Bilateral single sesion whole lung lavage under venous-venous ECMO in a case of severe pulmonary alveolar proteinosis: five years follow up
title_fullStr Bilateral single sesion whole lung lavage under venous-venous ECMO in a case of severe pulmonary alveolar proteinosis: five years follow up
title_full_unstemmed Bilateral single sesion whole lung lavage under venous-venous ECMO in a case of severe pulmonary alveolar proteinosis: five years follow up
title_sort bilateral single sesion whole lung lavage under venous-venous ecmo in a case of severe pulmonary alveolar proteinosis: five years follow up
description Introduction: Pulmonary alveolar proteinosis (PAP) is a rare disease caused by accumulation of proteinaceous material in the alveolar spaces. The most common mechanism implied is the development of antibodies directed to granulocyte macrophage colony stimulating factor (GM-CSF). which inhibits activation of alveolar macrophage, thereby causing accumulation of surfactant. Standard treatment is considered to be whole lung lavage (WLL). Object: We present the case of a 47 years old woman referred for lung transplantation because of combined lung fibrosis and emphysema. Diagnose was change to respiratory failure secondary to PAP. We performed a single cession bilateral WLL under venous-venous ECMO. After  a 5 years follow up, the patients remains asymptomatic and with normal pulmonary physiology.Conclusions: The case highlights the importance of careful examination of previous diagnoses, in particular of cases referred for lung transplantation and provides factibility of performing single session bilateral WLL without causing right heart failure. 
publisher Universidad Nacional Cba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
publishDate 2019
url https://revistas.unc.edu.ar/index.php/med/article/view/22595
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