Utility of mycophenolate mycophenolate mofetil in lupus nephritis

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Mofetil mycophenolate (MM) is an immunosuppressive agent that was initially used to prevent rejection in solid organ transplantation, and was later used to treat systemic autoimmune diseases. In Systemic Lupus Erythematosus (SLE) it was initially used for the treatment of Lupus Nephropathy (LN) and...

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Autores principales: Savio, Veronica, Alba, Paula, Babini, Alejandra M.
Formato: Artículo revista
Lenguaje:Español
Publicado: Universidad Nacional Cba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2012
Acceso en línea:https://revistas.unc.edu.ar/index.php/med/article/view/20885
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Revistas de la UNC de Universidad Nacional de Córdoba
id I10-R10article-20885
record_format ojs
institution Universidad Nacional de Córdoba
institution_str I-10
repository_str R-10
container_title_str Revistas de la UNC
language Español
format Artículo revista
author Savio, Veronica
Alba, Paula
Babini, Alejandra M.
spellingShingle Savio, Veronica
Alba, Paula
Babini, Alejandra M.
Utility of mycophenolate mycophenolate mofetil in lupus nephritis
author_facet Savio, Veronica
Alba, Paula
Babini, Alejandra M.
author_sort Savio, Veronica
title Utility of mycophenolate mycophenolate mofetil in lupus nephritis
title_short Utility of mycophenolate mycophenolate mofetil in lupus nephritis
title_full Utility of mycophenolate mycophenolate mofetil in lupus nephritis
title_fullStr Utility of mycophenolate mycophenolate mofetil in lupus nephritis
title_full_unstemmed Utility of mycophenolate mycophenolate mofetil in lupus nephritis
title_sort utility of mycophenolate mycophenolate mofetil in lupus nephritis
description Mofetil mycophenolate (MM) is an immunosuppressive agent that was initially used to prevent rejection in solid organ transplantation, and was later used to treat systemic autoimmune diseases. In Systemic Lupus Erythematosus (SLE) it was initially used for the treatment of Lupus Nephropathy (LN) and is now considered an important alternative agent for LN refractory to other drugs as well as in induction therapy with promising results and lower toxicity1-3. The first studies were limited to describing series with small numbers of patients where MM was used to treat patients with Cyclophosphamide (CF) and Azathioprine (AZA) resistant disease with favorable results. Subsequently several randomised studies have shown satisfactory results in the treatment of LN in both induction of remission and maintenance compared to the use of CF and AZA6-9.The good results obtained in the treatment of NL led to the MM being used for the treatment of other manifestations of the disease, such as vasculitis, neurological, skin, haematological and signs or symptoms of disease activity in general.
publisher Universidad Nacional Cba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
publishDate 2012
url https://revistas.unc.edu.ar/index.php/med/article/view/20885
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