Surveillance of Sensitivity to Penicillin in streptococcus Agalactiae recovered from pregnant women between 35-37 weeks of gestation.

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Streptococcus agalactiae (GBS) cause severe infections in newborns under three months. Meningitis, pneumonia and sepsis are the main infectious diseases in these children. These infections are among the most serious that an individual can suffer in his first twelve hours of life. The child acquires...

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Autores principales: Müller Velázquez, Lucía, Bobadilla, Fernando, Novosak, Marina, Cortese, Iliana, Laczeski, Margarita
Formato: Artículo revista
Lenguaje:Español
Publicado: Universidad Nacional Cba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2017
Materias:
streptococcus agalactiae
GBS
antimicrobial
penicillin
intrapartum prophylaxis
Streptococcus agalactiae
SGB
antimicrobiano
penicilina
profilaxis intraparto
Acceso en línea:https://revistas.unc.edu.ar/index.php/med/article/view/16395
Aporte de:
Revistas de la UNC de Universidad Nacional de Córdoba
id I10-R10article-16395
record_format ojs
institution Universidad Nacional de Córdoba
institution_str I-10
repository_str R-10
container_title_str Revistas de la UNC
language Español
format Artículo revista
topic streptococcus agalactiae
GBS
antimicrobial
penicillin
intrapartum prophylaxis
Streptococcus agalactiae
SGB
antimicrobiano
penicilina
profilaxis intraparto
spellingShingle streptococcus agalactiae
GBS
antimicrobial
penicillin
intrapartum prophylaxis
Streptococcus agalactiae
SGB
antimicrobiano
penicilina
profilaxis intraparto
Müller Velázquez, Lucía
Bobadilla, Fernando
Novosak, Marina
Cortese, Iliana
Laczeski, Margarita
Surveillance of Sensitivity to Penicillin in streptococcus Agalactiae recovered from pregnant women between 35-37 weeks of gestation.
topic_facet streptococcus agalactiae
GBS
antimicrobial
penicillin
intrapartum prophylaxis
Streptococcus agalactiae
SGB
antimicrobiano
penicilina
profilaxis intraparto
author Müller Velázquez, Lucía
Bobadilla, Fernando
Novosak, Marina
Cortese, Iliana
Laczeski, Margarita
author_facet Müller Velázquez, Lucía
Bobadilla, Fernando
Novosak, Marina
Cortese, Iliana
Laczeski, Margarita
author_sort Müller Velázquez, Lucía
title Surveillance of Sensitivity to Penicillin in streptococcus Agalactiae recovered from pregnant women between 35-37 weeks of gestation.
title_short Surveillance of Sensitivity to Penicillin in streptococcus Agalactiae recovered from pregnant women between 35-37 weeks of gestation.
title_full Surveillance of Sensitivity to Penicillin in streptococcus Agalactiae recovered from pregnant women between 35-37 weeks of gestation.
title_fullStr Surveillance of Sensitivity to Penicillin in streptococcus Agalactiae recovered from pregnant women between 35-37 weeks of gestation.
title_full_unstemmed Surveillance of Sensitivity to Penicillin in streptococcus Agalactiae recovered from pregnant women between 35-37 weeks of gestation.
title_sort surveillance of sensitivity to penicillin in streptococcus agalactiae recovered from pregnant women between 35-37 weeks of gestation.
description Streptococcus agalactiae (GBS) cause severe infections in newborns under three months. Meningitis, pneumonia and sepsis are the main infectious diseases in these children. These infections are among the most serious that an individual can suffer in his first twelve hours of life. The child acquires the infection by vertical transmission of the colonized mother. To prevent neonatal disease, penicillin is recommended as the drug of choice for intrapartum prophylaxis (PIP) in pregnant women colonized. However, strains with decreased susceptibility to penicillin have been detected so it is important to monitor the susceptibility to penicillin to ensure its usefulness during prophylaxis. The aim of this study was to determine the sensitivity to penicillin in GBS strains recovered from pregnant women with 35-37 weeks of gestation. Ninety-six isolates were studied and sensitivity was determined by the epsilometric method Etest® (LIOFILCHEM, Italy), following the recommendations of the Clinical Laboratory Standards Institute (CLSI). Minimum Inhibitory Concentration (MIC) was obtained for each bacterial isolation. 100% (96) of the strains studied were sensitive to penicillin with MIC values between 0.012 and 0.094 ?g mL-1. These results indicate that penicillin remains the antimicrobial of choice during intrapartum prophylaxis, for the prevention of neonatal disease caused by GBS in our region. The importance of epidemiological surveillance of sensitivity to penicillin and other antimicrobials is highlighted in order to alert new resistance mechanisms and to adapt treatment strategies.
publisher Universidad Nacional Cba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
publishDate 2017
url https://revistas.unc.edu.ar/index.php/med/article/view/16395
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