Memoria de trabajo, control inhibitorio y flexibilidad cognitiva en pacientes con diferentes grados de severidad en la Enfermedad de Alzheimer

Executive Functions (EF) are a series of processes of high cognitive hierarchy that mediate behavior for problem solving. Alzheimer`s Disease (AD) is a neurodegenerative disease that produces executive impairment in the components of Working Memory (WM), inhibitory control and cognitive flexibility....

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Autores principales: Cañas Lucendo, Manuel, Perea Bartolomé, María Victoria, Ladera Fernandez, Valentina
Formato: Artículo revista
Lenguaje:Español
Publicado: Universidad Nacional de Córdoba 2022
Materias:
Enfermedad de Alzheimer
control inhibitorio
flexibilidad cognitiva
funcion ejecutiva
memoria de trabajo
Acceso en línea:https://revistas.unc.edu.ar/index.php/racc/article/view/30675
Aporte de:
Revistas de la UNC de Universidad Nacional de Córdoba
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spelling I10-R10-article-306752022-08-31T13:25:44Z Memoria de trabajo, control inhibitorio y flexibilidad cognitiva en pacientes con diferentes grados de severidad en la Enfermedad de Alzheimer Cañas Lucendo, Manuel Perea Bartolomé, María Victoria Ladera Fernandez, Valentina Enfermedad de Alzheimer control inhibitorio flexibilidad cognitiva funcion ejecutiva memoria de trabajo Executive Functions (EF) are a series of processes of high cognitive hierarchy that mediate behavior for problem solving. Alzheimer`s Disease (AD) is a neurodegenerative disease that produces executive impairment in the components of Working Memory (WM), inhibitory control and cognitive flexibility. The objective of the study was to investigate the executive components affected in patients with AD according to the degree of severity, in comparison with Subjects without cognitive impairment (SWCI). 50 patients with AD and 60 SWCI were studied in a non-experimental-cross-sectional study with non-probabilistic sampling based on a series of inclusion criteria. After the application of the digit subtest (WAIS-III), Stroop test, abbreviated Wisconsin classification card test, Trail making test, part B, the results showed that the WM did not differentiate between patients with mild AD and those with SWCI, inhibitory control makes it possible to differentiate between patients with AD in a moderate and severe phase, in contrast to those in a mild state, and with regard to cognitive flexibility, there are no inconsistent differences between the different degrees of severity, with the exception of those found among those with mild and moderate AD and among the moderately severe with SWCI. In conclusion, patients with AD have greater impairment in WM, inhibitory control and cognitive flexibility, regardless of the degree of severity and age, compared to SWCI. El objetivo del estudio consistió en investigar las Funciones Ejecutivas (FE) en pacientes con Enfermedad de Alzheimer (EA) en función del grado de severidad. Se estudiaron 50 pacientes con EA y 60 Sujetos sin deterioro cognitivo (SSDC) en un estudio no experimental- transversal con un muestreo no probabilístico. Los resultados demostraron que: la ejecución del test de dígitos que valora memoria de trabajo, no diferencia entre los pacientes con EA leve y los SSDC; el control inhibitorio, evaluado mediante el test de Stroop, permite diferenciar a los pacientes con EA en fase moderada y grave; y en la flexibilidad cognitiva, medida a través de diferentes variables, existen diferencias inconsistentes. Los pacientes con EA tienen mayor afectación en tareas que evalúan memoria de trabajo, control inhibitorio y la flexibilidad cognitiva, con independencia del grado de severidad y de la edad, en comparación con SSDC. Universidad Nacional de Córdoba 2022-08-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://revistas.unc.edu.ar/index.php/racc/article/view/30675 Argentinean Journal of Behavioral Sciences; Vol. 14 No. 2 (2022): Revista Argentina de Ciencias del Comportamiento; 49-63 Revista Argentina de Ciencias del Comportamiento; Vol. 14 Núm. 2 (2022): Revista Argentina de Ciencias del Comportamiento; 49-63 1852-4206 10.32348/1852.4206.v14.n2 spa https://revistas.unc.edu.ar/index.php/racc/article/view/30675/38684 https://revistas.unc.edu.ar/index.php/racc/article/view/30675/37735 Derechos de autor 2022 Manuel Cañas Lucendo, María Victoria Perea Bartolomé, Valentina Ladera Fernandez http://creativecommons.org/licenses/by/4.0
institution Universidad Nacional de Córdoba
institution_str I-10
repository_str R-10
container_title_str Revistas de la UNC
language Español
format Artículo revista
topic Enfermedad de Alzheimer
control inhibitorio
flexibilidad cognitiva
funcion ejecutiva
memoria de trabajo
spellingShingle Enfermedad de Alzheimer
control inhibitorio
flexibilidad cognitiva
funcion ejecutiva
memoria de trabajo
Cañas Lucendo, Manuel
Perea Bartolomé, María Victoria
Ladera Fernandez, Valentina
Memoria de trabajo, control inhibitorio y flexibilidad cognitiva en pacientes con diferentes grados de severidad en la Enfermedad de Alzheimer
topic_facet Enfermedad de Alzheimer
control inhibitorio
flexibilidad cognitiva
funcion ejecutiva
memoria de trabajo
author Cañas Lucendo, Manuel
Perea Bartolomé, María Victoria
Ladera Fernandez, Valentina
author_facet Cañas Lucendo, Manuel
Perea Bartolomé, María Victoria
Ladera Fernandez, Valentina
author_sort Cañas Lucendo, Manuel
title Memoria de trabajo, control inhibitorio y flexibilidad cognitiva en pacientes con diferentes grados de severidad en la Enfermedad de Alzheimer
title_short Memoria de trabajo, control inhibitorio y flexibilidad cognitiva en pacientes con diferentes grados de severidad en la Enfermedad de Alzheimer
title_full Memoria de trabajo, control inhibitorio y flexibilidad cognitiva en pacientes con diferentes grados de severidad en la Enfermedad de Alzheimer
title_fullStr Memoria de trabajo, control inhibitorio y flexibilidad cognitiva en pacientes con diferentes grados de severidad en la Enfermedad de Alzheimer
title_full_unstemmed Memoria de trabajo, control inhibitorio y flexibilidad cognitiva en pacientes con diferentes grados de severidad en la Enfermedad de Alzheimer
title_sort memoria de trabajo, control inhibitorio y flexibilidad cognitiva en pacientes con diferentes grados de severidad en la enfermedad de alzheimer
description Executive Functions (EF) are a series of processes of high cognitive hierarchy that mediate behavior for problem solving. Alzheimer`s Disease (AD) is a neurodegenerative disease that produces executive impairment in the components of Working Memory (WM), inhibitory control and cognitive flexibility. The objective of the study was to investigate the executive components affected in patients with AD according to the degree of severity, in comparison with Subjects without cognitive impairment (SWCI). 50 patients with AD and 60 SWCI were studied in a non-experimental-cross-sectional study with non-probabilistic sampling based on a series of inclusion criteria. After the application of the digit subtest (WAIS-III), Stroop test, abbreviated Wisconsin classification card test, Trail making test, part B, the results showed that the WM did not differentiate between patients with mild AD and those with SWCI, inhibitory control makes it possible to differentiate between patients with AD in a moderate and severe phase, in contrast to those in a mild state, and with regard to cognitive flexibility, there are no inconsistent differences between the different degrees of severity, with the exception of those found among those with mild and moderate AD and among the moderately severe with SWCI. In conclusion, patients with AD have greater impairment in WM, inhibitory control and cognitive flexibility, regardless of the degree of severity and age, compared to SWCI.
publisher Universidad Nacional de Córdoba
publishDate 2022
url https://revistas.unc.edu.ar/index.php/racc/article/view/30675
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AT pereabartolomemariavictoria memoriadetrabajocontrolinhibitorioyflexibilidadcognitivaenpacientescondiferentesgradosdeseveridadenlaenfermedaddealzheimer
AT laderafernandezvalentina memoriadetrabajocontrolinhibitorioyflexibilidadcognitivaenpacientescondiferentesgradosdeseveridadenlaenfermedaddealzheimer
first_indexed 2022-10-04T12:16:28Z
last_indexed 2022-10-04T12:16:28Z
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