Genital and extragenital infection by Chlamydia trachomatis: Holistic study of patients from Córdoba, Argentina
Chlamydia trachomatis (C. trachomatis) is the most prevalent bacterial sexually transmitted infection in the world. Taking into account the different sexual habits of people and the morphological similarity that exists between the oral and cervical epithelium, the objective of this work was...
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| Formato: | Artículo revista |
| Lenguaje: | Español |
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Universidad Nacional Cba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
2019
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| Acceso en línea: | https://revistas.unc.edu.ar/index.php/med/article/view/25835 |
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I10-R10-article-25835 |
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ojs |
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Universidad Nacional de Córdoba |
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I-10 |
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R-10 |
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Revistas de la UNC |
| language |
Español |
| format |
Artículo revista |
| topic |
chlamydia trachomatis. chlamydia trachomatis |
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chlamydia trachomatis. chlamydia trachomatis Kiguen, AX Mosmann, JP Sanguino, S Pizarro, P López de Blanc, S Talavera, A Venezuela, RF Cuffini, CG Genital and extragenital infection by Chlamydia trachomatis: Holistic study of patients from Córdoba, Argentina |
| topic_facet |
chlamydia trachomatis. chlamydia trachomatis |
| author |
Kiguen, AX Mosmann, JP Sanguino, S Pizarro, P López de Blanc, S Talavera, A Venezuela, RF Cuffini, CG |
| author_facet |
Kiguen, AX Mosmann, JP Sanguino, S Pizarro, P López de Blanc, S Talavera, A Venezuela, RF Cuffini, CG |
| author_sort |
Kiguen, AX |
| title |
Genital and extragenital infection by Chlamydia trachomatis: Holistic study of patients from Córdoba, Argentina |
| title_short |
Genital and extragenital infection by Chlamydia trachomatis: Holistic study of patients from Córdoba, Argentina |
| title_full |
Genital and extragenital infection by Chlamydia trachomatis: Holistic study of patients from Córdoba, Argentina |
| title_fullStr |
Genital and extragenital infection by Chlamydia trachomatis: Holistic study of patients from Córdoba, Argentina |
| title_full_unstemmed |
Genital and extragenital infection by Chlamydia trachomatis: Holistic study of patients from Córdoba, Argentina |
| title_sort |
genital and extragenital infection by chlamydia trachomatis: holistic study of patients from córdoba, argentina |
| description |
Chlamydia trachomatis (C. trachomatis) is the most prevalent bacterial sexually transmitted infection in the world. Taking into account the different sexual habits of people and the morphological similarity that exists between the oral and cervical epithelium, the objective of this work was to determine the presence of C. trachomatis in oral and genital mucosa of patients from the city of Córdoba, Argentina.
An observational, cross-sectional study was carried out with an interdisciplinary team formed by phisicians (microbiologist, gynecologist, proctologist, infectologist) dentists, biochemists and geneticist. Oral and anogenital 133 samples in 53 patients (31 female and 22 male patients) were obtained in the period of one year (May 2018 / May 2019). Patients included in this study had any injury to any of the mucous studied. Those who did not have injuries or did not want to participate in the study were excluded. The samples underwent DNA extraction. The samples were subsequently analyzed by PCR with primers CTP1 / CTP2 for the detection of the OmpA gene of C. trachomatis.
The age range of the 53 patients studied was 19 to 78 years, with a median of 41 years. Oral and anogenital samples were taken from all of them, after signing the consent approved by the Ethics Committee belonging to the Facultad de Odontología, UNC. Presence of C. trachomatis was found in 16 (30%) patients; 12 (75%) women and 4 (25%) men. Out of the 133 samples studied, 26 (19.5%) were positive; 73% (19/26) in anogenital mucosa and the remaining 27% (7/26) in oral mucosa. Importantly, the presence of C. trachomatis in both mucosae was determined in 8 patients.
It is the first study in Argentina where the patient is studied integrally (oral and anogenital mucous membranes). High prevalence of C. trachomatis infection was detected with a greater tendency in women. These results demonstrate the importance of studying this bacterium in extragenital sites and for this, the interdisciplinary work of the health team is essential to achieve a holistic study of the patient and thus arrive at a good diagnosis and subsequent treatment of the same. |
| publisher |
Universidad Nacional Cba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología |
| publishDate |
2019 |
| url |
https://revistas.unc.edu.ar/index.php/med/article/view/25835 |
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I10-R10-article-258352019-11-11T21:18:27Z Genital and extragenital infection by Chlamydia trachomatis: Holistic study of patients from Córdoba, Argentina Infección genital y extragenital por Chlamydia trachomatis: Estudio holístico de pacientes de Córdoba, Argentina Kiguen, AX Mosmann, JP Sanguino, S Pizarro, P López de Blanc, S Talavera, A Venezuela, RF Cuffini, CG chlamydia trachomatis. chlamydia trachomatis Chlamydia trachomatis (C. trachomatis) is the most prevalent bacterial sexually transmitted infection in the world. Taking into account the different sexual habits of people and the morphological similarity that exists between the oral and cervical epithelium, the objective of this work was to determine the presence of C. trachomatis in oral and genital mucosa of patients from the city of Córdoba, Argentina. An observational, cross-sectional study was carried out with an interdisciplinary team formed by phisicians (microbiologist, gynecologist, proctologist, infectologist) dentists, biochemists and geneticist. Oral and anogenital 133 samples in 53 patients (31 female and 22 male patients) were obtained in the period of one year (May 2018 / May 2019). Patients included in this study had any injury to any of the mucous studied. Those who did not have injuries or did not want to participate in the study were excluded. The samples underwent DNA extraction. The samples were subsequently analyzed by PCR with primers CTP1 / CTP2 for the detection of the OmpA gene of C. trachomatis. The age range of the 53 patients studied was 19 to 78 years, with a median of 41 years. Oral and anogenital samples were taken from all of them, after signing the consent approved by the Ethics Committee belonging to the Facultad de Odontología, UNC. Presence of C. trachomatis was found in 16 (30%) patients; 12 (75%) women and 4 (25%) men. Out of the 133 samples studied, 26 (19.5%) were positive; 73% (19/26) in anogenital mucosa and the remaining 27% (7/26) in oral mucosa. Importantly, the presence of C. trachomatis in both mucosae was determined in 8 patients. It is the first study in Argentina where the patient is studied integrally (oral and anogenital mucous membranes). High prevalence of C. trachomatis infection was detected with a greater tendency in women. These results demonstrate the importance of studying this bacterium in extragenital sites and for this, the interdisciplinary work of the health team is essential to achieve a holistic study of the patient and thus arrive at a good diagnosis and subsequent treatment of the same. Chlamydia trachomatis (C. trachomatis) es la Infección de Transmisión Sexual bacteriana mas prevalente en el mundo. Teniendo en cuenta los diferentes hábitos sexuales de las personas y la semejanza morfológica que existe entre el epitelio oral y cervical, el objetivo de este trabajo fue determinar la presencia de C. trachomatis en mucosa oral y genital de pacientes de la ciudad de Córdoba, Argentina. Se realizó un estudio observacional, transversal, con un equipo interdisciplinario formado por Médicos (microbiólogo, ginecólogo, proctólogo, infectólogo) odontólogos, bioquímicos y Lic. en Genética. Se obtuvieron 133 muestras orales y anogenitales pertenecientes a 53 pacientes (31 pacientes femeninas y 22 masculinos) en el período de un año (mayo 2018/mayo 2019). Los pacientes incluidos en este estudio tenían alguna lesión en alguna de las mucosas estudiadas. Quedaron excluidos quienes no tenían lesiones o no querían participar del estudio. A las muestras se les realizó una extracción de ADN. Posteriormente se analizaron las muestras mediante PCR con los cebadores CTP1/CTP2 para la detección del gen OmpA de C. trachomatis. Se estudiaron 53 pacientes de 19 a 78 años, con una media de 41 años de edad. A todos se les tomaron muestras orales y anogenitales, luego de firmar el consentimiento aprobado por el Comité de Ética perteneciente a la Facultad de Odontología de UNC. En 16 (30%) pacientes se encontró la presencia de C. trachomatis; 12 (75%) mujeres y 4 (25%) hombres. De las 133 muestras estudiadas 26 (19,5%) resultaron positivas; el 73% (19/26) en mucosa anogenital y el 27% restante (7/26) en mucosa oral. Es importante destacar que en 8 pacientes se determinó la presencia de C. trachomatis en ambas mucosas. Es el primer estudio en Argentina en donde el paciente es estudiado integralmente (mucosas orales y anogenitales). Se detectó alta prevalencia de infección por C. trachomatis con mayor tendencia en mujeres. Estos resultados demuestran la importancia de estudiar a esta bacteria en sitios extragenitales y para esto es esencial el trabajo interdisciplinario del equipo de salud para lograr un estudio holístico del paciente y llegar, de esta manera, a un buen diagnóstico y posterior tratamiento del mismo Universidad Nacional Cba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2019-10-18 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://revistas.unc.edu.ar/index.php/med/article/view/25835 Revista de la Facultad de Ciencias Médicas de Córdoba.; 2019: Suplemento JIC XX Revista de la Facultad de Ciencias Médicas de Córdoba; 2019: Suplemento JIC XX Revista da Faculdade de Ciências Médicas de Córdoba; 2019: Suplemento JIC XX 1853-0605 0014-6722 spa https://revistas.unc.edu.ar/index.php/med/article/view/25835/27673 Derechos de autor 2019 Universidad Nacional de Córdoba |