Intraepithelial cervical lesions: relationship between cytology and biopsy.

Mostrar todas las versiones(2)

The International Agency for Research on Cancer estimated for Argentina in 2018 that cervical cancer would take the third place in female cancer, after breast carcinoma and colorrectal cancer. Pap test is the main instrument for early detection. Multiple factors favor the development of this ne...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Alcain, WL, Matínez, EA, Rodríguez, NH, Saavedra, NA, Imahorn, J, Negri, I, Moreno, SE, Cremonezzi, DC
Formato: Artículo revista
Lenguaje:Español
Publicado: Universidad Nacional Cba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2019
Materias:
citology
cervical cancer
SIL
HPV
citología
cáncer de cuello uterino
Acceso en línea:https://revistas.unc.edu.ar/index.php/med/article/view/25707
Aporte de:
Revistas de la UNC de Universidad Nacional de Córdoba
id I10-R10-article-25707
record_format ojs
institution Universidad Nacional de Córdoba
institution_str I-10
repository_str R-10
container_title_str Revistas de la UNC
language Español
format Artículo revista
topic citology
cervical cancer
SIL
HPV
citología
cáncer de cuello uterino
SIL
HPV
spellingShingle citology
cervical cancer
SIL
HPV
citología
cáncer de cuello uterino
SIL
HPV
Alcain, WL
Matínez, EA
Rodríguez, NH
Saavedra, NA
Imahorn, J
Negri, I
Moreno, SE
Cremonezzi, DC
Intraepithelial cervical lesions: relationship between cytology and biopsy.
topic_facet citology
cervical cancer
SIL
HPV
citología
cáncer de cuello uterino
SIL
HPV
author Alcain, WL
Matínez, EA
Rodríguez, NH
Saavedra, NA
Imahorn, J
Negri, I
Moreno, SE
Cremonezzi, DC
author_facet Alcain, WL
Matínez, EA
Rodríguez, NH
Saavedra, NA
Imahorn, J
Negri, I
Moreno, SE
Cremonezzi, DC
author_sort Alcain, WL
title Intraepithelial cervical lesions: relationship between cytology and biopsy.
title_short Intraepithelial cervical lesions: relationship between cytology and biopsy.
title_full Intraepithelial cervical lesions: relationship between cytology and biopsy.
title_fullStr Intraepithelial cervical lesions: relationship between cytology and biopsy.
title_full_unstemmed Intraepithelial cervical lesions: relationship between cytology and biopsy.
title_sort intraepithelial cervical lesions: relationship between cytology and biopsy.
description The International Agency for Research on Cancer estimated for Argentina in 2018 that cervical cancer would take the third place in female cancer, after breast carcinoma and colorrectal cancer. Pap test is the main instrument for early detection. Multiple factors favor the development of this neoplasia, being VPH one of them. The aim of this study is to state the findings of cervical cytology with diagnosis of low (L-SIL) and high grade (H-SIL) intraepithelial cervical lesion with the corresponding histopathology, and determine age frequency. A study was carried out of cervix incisional (partial) biopsies and cervical citologies of reports of 5 years (June 2013 to November 2018) carried out in Hospital Nacional de Clínicas. 324 pap smears with diagnosis of intraepithelial cervix lesion (199 L-SIL and 125 H-SIL) were gathered. 81 included a further histopathologic study, being these ones subject of analysis (n=81). 48 out of these were L-SIL (59%) and 33 H-SIL (41%). Regarding the distribution of age frequency, in groups of 20-39 and 40-59 years old L-SIL were predominant, and H-SIL in older than 60 years old. Consistency between the cytologic and histological diagnosis was 53%. In L-SIL was 46% and in H-SIL 64%. These data were analyzed with the Chi-square association test (Pearson Test) and it was considered a level of significance p<0,05. An association was found among the percentage of patients with consistent and inconsistent diagnoses with the type of lesion (<0,001). No significant differences between consistencies and inconsistencies in low-grade lesions (p=0,4) were found, but there were differences among high-grade lesions, with a greater number of matches/consistencies (p<0,01). The results obtained in our study reveal that cervical citology remains a quick, simple and cheap screening method. In spite of the cito-histological inconsitencies in a great number of cases, it should be noted that in high-grade lesions, where a prompt treatment is required, cytology has a high performance.
publisher Universidad Nacional Cba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
publishDate 2019
url https://revistas.unc.edu.ar/index.php/med/article/view/25707
work_keys_str_mv AT alcainwl intraepithelialcervicallesionsrelationshipbetweencytologyandbiopsy
AT matinezea intraepithelialcervicallesionsrelationshipbetweencytologyandbiopsy
AT rodrigueznh intraepithelialcervicallesionsrelationshipbetweencytologyandbiopsy
AT saavedrana intraepithelialcervicallesionsrelationshipbetweencytologyandbiopsy
AT imahornj intraepithelialcervicallesionsrelationshipbetweencytologyandbiopsy
AT negrii intraepithelialcervicallesionsrelationshipbetweencytologyandbiopsy
AT morenose intraepithelialcervicallesionsrelationshipbetweencytologyandbiopsy
AT cremonezzidc intraepithelialcervicallesionsrelationshipbetweencytologyandbiopsy
AT alcainwl lesionesintraepitelialesescamosasdecuellouterinorelacionentrecitologiaybiopsia
AT matinezea lesionesintraepitelialesescamosasdecuellouterinorelacionentrecitologiaybiopsia
AT rodrigueznh lesionesintraepitelialesescamosasdecuellouterinorelacionentrecitologiaybiopsia
AT saavedrana lesionesintraepitelialesescamosasdecuellouterinorelacionentrecitologiaybiopsia
AT imahornj lesionesintraepitelialesescamosasdecuellouterinorelacionentrecitologiaybiopsia
AT negrii lesionesintraepitelialesescamosasdecuellouterinorelacionentrecitologiaybiopsia
AT morenose lesionesintraepitelialesescamosasdecuellouterinorelacionentrecitologiaybiopsia
AT cremonezzidc lesionesintraepitelialesescamosasdecuellouterinorelacionentrecitologiaybiopsia
first_indexed 2022-08-20T01:26:38Z
last_indexed 2022-08-20T01:26:38Z
_version_ 1770719009966129152
spelling I10-R10-article-257072019-11-11T21:18:27Z Intraepithelial cervical lesions: relationship between cytology and biopsy. Lesiones intraepiteliales escamosas de cuello uterino: relación entre citología y biopsia. Alcain, WL Matínez, EA Rodríguez, NH Saavedra, NA Imahorn, J Negri, I Moreno, SE Cremonezzi, DC citology cervical cancer SIL HPV citología cáncer de cuello uterino SIL HPV The International Agency for Research on Cancer estimated for Argentina in 2018 that cervical cancer would take the third place in female cancer, after breast carcinoma and colorrectal cancer. Pap test is the main instrument for early detection. Multiple factors favor the development of this neoplasia, being VPH one of them. The aim of this study is to state the findings of cervical cytology with diagnosis of low (L-SIL) and high grade (H-SIL) intraepithelial cervical lesion with the corresponding histopathology, and determine age frequency. A study was carried out of cervix incisional (partial) biopsies and cervical citologies of reports of 5 years (June 2013 to November 2018) carried out in Hospital Nacional de Clínicas. 324 pap smears with diagnosis of intraepithelial cervix lesion (199 L-SIL and 125 H-SIL) were gathered. 81 included a further histopathologic study, being these ones subject of analysis (n=81). 48 out of these were L-SIL (59%) and 33 H-SIL (41%). Regarding the distribution of age frequency, in groups of 20-39 and 40-59 years old L-SIL were predominant, and H-SIL in older than 60 years old. Consistency between the cytologic and histological diagnosis was 53%. In L-SIL was 46% and in H-SIL 64%. These data were analyzed with the Chi-square association test (Pearson Test) and it was considered a level of significance p<0,05. An association was found among the percentage of patients with consistent and inconsistent diagnoses with the type of lesion (<0,001). No significant differences between consistencies and inconsistencies in low-grade lesions (p=0,4) were found, but there were differences among high-grade lesions, with a greater number of matches/consistencies (p<0,01). The results obtained in our study reveal that cervical citology remains a quick, simple and cheap screening method. In spite of the cito-histological inconsitencies in a great number of cases, it should be noted that in high-grade lesions, where a prompt treatment is required, cytology has a high performance. La Agencia de Investigación Internacional de Investigación sobre cáncer (IARC) estimó para Argentina en 2018, el cáncer cervicouterino ocuparía el tercer lugar de cáncer femenino, después del carcinoma de mama y colorrectal. El examen de Papanicolaou constituye la principal herramienta de detección temprana. Existen múltiples factores que favorecen el desarrollo de esta neoplasia, siendo el VPH uno de ellos. El objetivo del presente trabajo es relacionar los hallazgos de citologías con diagnóstico de lesión intraepitelial cervical de bajo (L-SIL) y alto grado (H-SIL) con la histopatología correspondiente, y determinar la frecuencia por edades. Se realizó un estudio con informes de citologías y biopsias incisionales (parciales) de cérvix realizadas en el Hospital Nacional de Clínicas en 5 años (junio de 2013 a noviembre de 2018). Se obtuvieron 324 citologías con diagnóstico de lesión intraepitelial cervical (199  L-SIL  y 125 H-SIL). 81 contaban con un estudio histopatológico posterior, siendo éstas las que se analizaron (n=81). De este total 48 fueron L-SIL (59%) y 33 fueron H-SIL (41%). Con respecto a la distribución de frecuencias por edades, en los grupos de 20-39 y de 40-59 años predominaron L-SIL, y en mayores de 60 años H-SIL. La coincidencia entre el diagnóstico citológico e histológico fue de un 53%. En cuanto a los L-SIL fue de 46% y, en los H-SIL de 64%. Estos datos fueron analizados con el test de asociación Chi Cuadrado (Test de Pearson) y se consideró un nivel de significación de p <0,05. Existió asociación entre los porcentajes de pacientes con diagnósticos coincidentes y no coincidentes con el tipo de lesión (<0,001). No se encontraron diferencias significativas entre coincidencias y no coincidencias en las lesiones de bajo grado (p=0,4), pero sí entre las de alto grado, con un mayor número de coincidencias (p<0,01) Los resultados obtenidos en nuestro estudio ponen de manifiesto que la citología cervical sigue siendo un método de screening rápido, sencillo y de bajo costo. A pesar de la falta de coincidencia cito-histológica en un importante número de casos se debe destacar que en las lesiones de alto grado, donde es necesario un tratamiento oportuno, la citología tiene un alto rendimiento. Universidad Nacional Cba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2019-10-10 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://revistas.unc.edu.ar/index.php/med/article/view/25707 Revista de la Facultad de Ciencias Médicas de Córdoba.; 2019: Suplemento JIC XX Revista de la Facultad de Ciencias Médicas de Córdoba; 2019: Suplemento JIC XX Revista da Faculdade de Ciências Médicas de Córdoba; 2019: Suplemento JIC XX 1853-0605 0014-6722 spa https://revistas.unc.edu.ar/index.php/med/article/view/25707/27404 Derechos de autor 2019 Universidad Nacional de Córdoba

Ejemplares similares