Analysis of the decrease in deaths due to coronary disease between 1995 and 2010. IMPACT CHD Argentina Study

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Objective: To quantify the contribution of risk factors and treatments in the reduction of mortality due to coronary heart disease in Argentina between 1995 and 2010.Methods: We used the validated IMPACTCHD model integrating data on effectiveness, use of treatments and changes in the risk factors be...

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Autores principales: Vicens, Jimena, Perman, Gastón, Aliperti, Valeria, Masson, Walter, Schargrodsky, Herman, Pramparo, Palmira, Ferrante, Daniel, Figar, Silvana, Capewell, Simon, O’Flaherty, Martín
Formato: Artículo revista
Lenguaje:Español
Publicado: Universidad Nacional Cba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2019
Materias:
coronary disease
risk factors
therapeutics
mortality
epidemiology
enfermedad coronaria
factores de riesgo
terapéutica
mortalidad
epidemiología.
Acceso en línea:https://revistas.unc.edu.ar/index.php/med/article/view/22915
Aporte de:
Revistas de la UNC de Universidad Nacional de Córdoba
id I10-R10-article-22915
record_format ojs
institution Universidad Nacional de Córdoba
institution_str I-10
repository_str R-10
container_title_str Revistas de la UNC
language Español
format Artículo revista
topic coronary disease
risk factors
therapeutics
mortality
epidemiology
enfermedad coronaria
factores de riesgo
terapéutica
mortalidad
epidemiología.
spellingShingle coronary disease
risk factors
therapeutics
mortality
epidemiology
enfermedad coronaria
factores de riesgo
terapéutica
mortalidad
epidemiología.
Vicens, Jimena
Perman, Gastón
Aliperti, Valeria
Masson, Walter
Schargrodsky, Herman
Pramparo, Palmira
Ferrante, Daniel
Figar, Silvana
Capewell, Simon
O’Flaherty, Martín
Analysis of the decrease in deaths due to coronary disease between 1995 and 2010. IMPACT CHD Argentina Study
topic_facet coronary disease
risk factors
therapeutics
mortality
epidemiology
enfermedad coronaria
factores de riesgo
terapéutica
mortalidad
epidemiología.
author Vicens, Jimena
Perman, Gastón
Aliperti, Valeria
Masson, Walter
Schargrodsky, Herman
Pramparo, Palmira
Ferrante, Daniel
Figar, Silvana
Capewell, Simon
O’Flaherty, Martín
author_facet Vicens, Jimena
Perman, Gastón
Aliperti, Valeria
Masson, Walter
Schargrodsky, Herman
Pramparo, Palmira
Ferrante, Daniel
Figar, Silvana
Capewell, Simon
O’Flaherty, Martín
author_sort Vicens, Jimena
title Analysis of the decrease in deaths due to coronary disease between 1995 and 2010. IMPACT CHD Argentina Study
title_short Analysis of the decrease in deaths due to coronary disease between 1995 and 2010. IMPACT CHD Argentina Study
title_full Analysis of the decrease in deaths due to coronary disease between 1995 and 2010. IMPACT CHD Argentina Study
title_fullStr Analysis of the decrease in deaths due to coronary disease between 1995 and 2010. IMPACT CHD Argentina Study
title_full_unstemmed Analysis of the decrease in deaths due to coronary disease between 1995 and 2010. IMPACT CHD Argentina Study
title_sort analysis of the decrease in deaths due to coronary disease between 1995 and 2010. impact chd argentina study
description Objective: To quantify the contribution of risk factors and treatments in the reduction of mortality due to coronary heart disease in Argentina between 1995 and 2010.Methods: We used the validated IMPACTCHD model integrating data on effectiveness, use of treatments and changes in the risk factors between 1995 and 2010 in people older than 25 years in Argentina. The difference between the coronary deaths observed and expected in 2010 was distributed between treatments and risk factors.Results: Between 1995 and 2010, adjusted mortality rates for coronary heart disease decreased 29.8% (8,500 deaths prevented or postponed - MPP). Improvements in treatments accounted for 49.9%, mostly secondary prevention of acute myocardial infarction (8.2%); antihypertensive treatment (11.9%) and treatment of heart failure (13.2%). Improvements in risk factors accounted for 32.9% of MPPs: systolic blood pressure 34.6%; total cholesterol 12.8%; smoking 6.8%. An excess of deaths was found due to the increase in diabetes (9.4%), obesity (6.9%) and sedentary lifestyle (5%). The 17.2% of the MPPs were not explained by the model.Conclusion: One out of every two MPP due to coronary heart disease in Argentina between 1995 and 2010 was due to treatments and one third to the improvement of risk factors. The decrease in blood pressure, cholesterol and smoking was limited by increases in the prevalence of obesity, sedentary lifestyle and diabetes. This study was possible thanks to the collaborative work to the cardiovascular epidemiology.
publisher Universidad Nacional Cba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
publishDate 2019
url https://revistas.unc.edu.ar/index.php/med/article/view/22915
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first_indexed 2022-08-20T01:26:15Z
last_indexed 2022-08-20T01:26:15Z
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spelling I10-R10-article-229152019-06-19T13:15:46Z Analysis of the decrease in deaths due to coronary disease between 1995 and 2010. IMPACT CHD Argentina Study Análisis del descenso de muertes por enfermedad coronaria entre 1995 y 2010. Estudio IMPACT CHD Argentina Vicens, Jimena Perman, Gastón Aliperti, Valeria Masson, Walter Schargrodsky, Herman Pramparo, Palmira Ferrante, Daniel Figar, Silvana Capewell, Simon O’Flaherty, Martín coronary disease risk factors therapeutics mortality epidemiology enfermedad coronaria factores de riesgo terapéutica mortalidad epidemiología. Objective: To quantify the contribution of risk factors and treatments in the reduction of mortality due to coronary heart disease in Argentina between 1995 and 2010.Methods: We used the validated IMPACTCHD model integrating data on effectiveness, use of treatments and changes in the risk factors between 1995 and 2010 in people older than 25 years in Argentina. The difference between the coronary deaths observed and expected in 2010 was distributed between treatments and risk factors.Results: Between 1995 and 2010, adjusted mortality rates for coronary heart disease decreased 29.8% (8,500 deaths prevented or postponed - MPP). Improvements in treatments accounted for 49.9%, mostly secondary prevention of acute myocardial infarction (8.2%); antihypertensive treatment (11.9%) and treatment of heart failure (13.2%). Improvements in risk factors accounted for 32.9% of MPPs: systolic blood pressure 34.6%; total cholesterol 12.8%; smoking 6.8%. An excess of deaths was found due to the increase in diabetes (9.4%), obesity (6.9%) and sedentary lifestyle (5%). The 17.2% of the MPPs were not explained by the model.Conclusion: One out of every two MPP due to coronary heart disease in Argentina between 1995 and 2010 was due to treatments and one third to the improvement of risk factors. The decrease in blood pressure, cholesterol and smoking was limited by increases in the prevalence of obesity, sedentary lifestyle and diabetes. This study was possible thanks to the collaborative work to the cardiovascular epidemiology. Objetivo: Cuantificar la contribución de los factores de riesgo (FR) y de los tratamientos en el descenso de mortalidad por enfermedad coronaria en Argentina entre 1995 y 2010.Métodos: Utilizamos el modelo validado IMPACTCHD integrando datos de efectividad y utilización de tratamientos y cambios en los FR en 1995 y 2010 en mayores de 25 años en Argentina. La diferencia entre las muertes coronarias observadas y esperadas en el 2010 se distribuyó entre los tratamientos y los FR.Resultados: Entre 1995 y 2010 las tasas ajustadas de mortalidad por enfermedad coronaria descendieron 29,8% (8 500 muertes prevenidas o pospuestas - MPP). Las mejoras en los tratamientos explicaron un 49,9%, en su mayoría por prevención secundaria del infarto agudo de miocardio (8,2%); tratamiento antihipertensivo (11,9%) y para insuficiencia cardíaca (13,2%). Las mejoras en los FR explicaron 32,9% de las MPP: presión arterial sistólica 34,6%; colesterol total 12,8%; tabaquismo 6,8%. Se encontró un exceso de muertes debido al aumento de diabetes (9,4%), obesidad (6,9%) y sedentarismo (5%). Un 17,2% de las MPP no fue explicado por el modelo.Conclusiones: Una de cada dos MPP por enfermedad coronaria en Argentina entre 1995 y 2010 se debió a los tratamientos y un tercio a la mejora de los FR. El descenso de la presión arterial, colesterol y tabaquismo fue limitado por aumentos en la prevalencia de obesidad, sedentarismo y diabetes. Este trabajo fue posible gracias al trabajo colaborativo en pos de la epidemiología cardiovascular. Universidad Nacional Cba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2019-06-19 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Modelo IMPACT CHD application/pdf text/html application/vnd.openxmlformats-officedocument.wordprocessingml.document application/vnd.openxmlformats-officedocument.wordprocessingml.document application/vnd.openxmlformats-officedocument.spreadsheetml.sheet application/vnd.openxmlformats-officedocument.spreadsheetml.sheet application/vnd.openxmlformats-officedocument.spreadsheetml.sheet application/vnd.openxmlformats-officedocument.spreadsheetml.sheet image/png https://revistas.unc.edu.ar/index.php/med/article/view/22915 Revista de la Facultad de Ciencias Médicas de Córdoba.; Vol. 76 No. 2 (2019); 92-100 Revista de la Facultad de Ciencias Médicas de Córdoba; Vol. 76 Núm. 2 (2019); 92-100 Revista da Faculdade de Ciências Médicas de Córdoba; v. 76 n. 2 (2019); 92-100 1853-0605 0014-6722 10.31053/1853.0605.v76.n2 spa https://revistas.unc.edu.ar/index.php/med/article/view/22915/23478 https://revistas.unc.edu.ar/index.php/med/article/view/22915/23662 https://revistas.unc.edu.ar/index.php/med/article/view/22915/27205 https://revistas.unc.edu.ar/index.php/med/article/view/22915/27206 https://revistas.unc.edu.ar/index.php/med/article/view/22915/27207 https://revistas.unc.edu.ar/index.php/med/article/view/22915/27208 https://revistas.unc.edu.ar/index.php/med/article/view/22915/27209 https://revistas.unc.edu.ar/index.php/med/article/view/22915/27210 https://revistas.unc.edu.ar/index.php/med/article/view/22915/27211 Derechos de autor 2019 Universidad Nacional de Córdoba

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