Incidence of hospital-acquired venous thromboembolic disease.

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Background: There is limited knowledge of the incidence of venous thromboembolic disease (VTE) during hospitalization, since most of these are community-based data.Purpose: To estimate the incidence rate (IR) of VTE developed during hospitalization.Methods: Prospective cohort of all inpatients admit...

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Autores principales: Grande Ratti, María Florencia, Posadas-Martínez, María Lourdes, Vicens, Jimena, González Bernaldo de Quirós, Fernán, Vázquez, Fernando Javier, Giunta, Diego Hernán
Formato: Artículo revista
Lenguaje:Inglés
Publicado: Universidad Nacional Cba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2018
Materias:
epidemiología
medicina hospitalaria
tromboembolismo venoso
epidemiology
hospital medicine
venous thromboembolism
Acceso en línea:https://revistas.unc.edu.ar/index.php/med/article/view/17243
Aporte de:
Revistas de la UNC de Universidad Nacional de Córdoba
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institution Universidad Nacional de Córdoba
institution_str I-10
repository_str R-10
container_title_str Revistas de la UNC
language Inglés
format Artículo revista
topic epidemiología
medicina hospitalaria
tromboembolismo venoso
epidemiology
hospital medicine
venous thromboembolism
spellingShingle epidemiología
medicina hospitalaria
tromboembolismo venoso
epidemiology
hospital medicine
venous thromboembolism
Grande Ratti, María Florencia
Posadas-Martínez, María Lourdes
Vicens, Jimena
González Bernaldo de Quirós, Fernán
Vázquez, Fernando Javier
Giunta, Diego Hernán
Incidence of hospital-acquired venous thromboembolic disease.
topic_facet epidemiología
medicina hospitalaria
tromboembolismo venoso
epidemiology
hospital medicine
venous thromboembolism
author Grande Ratti, María Florencia
Posadas-Martínez, María Lourdes
Vicens, Jimena
González Bernaldo de Quirós, Fernán
Vázquez, Fernando Javier
Giunta, Diego Hernán
author_facet Grande Ratti, María Florencia
Posadas-Martínez, María Lourdes
Vicens, Jimena
González Bernaldo de Quirós, Fernán
Vázquez, Fernando Javier
Giunta, Diego Hernán
author_sort Grande Ratti, María Florencia
title Incidence of hospital-acquired venous thromboembolic disease.
title_short Incidence of hospital-acquired venous thromboembolic disease.
title_full Incidence of hospital-acquired venous thromboembolic disease.
title_fullStr Incidence of hospital-acquired venous thromboembolic disease.
title_full_unstemmed Incidence of hospital-acquired venous thromboembolic disease.
title_sort incidence of hospital-acquired venous thromboembolic disease.
description Background: There is limited knowledge of the incidence of venous thromboembolic disease (VTE) during hospitalization, since most of these are community-based data.Purpose: To estimate the incidence rate (IR) of VTE developed during hospitalization.Methods: Prospective cohort of all inpatients admitted in a university tertiary hospital, in Argentina. The inclusion criteria were defined as: adult patients consecutively admitted from July/2006 to August/2013, for any cause. Patients admitted for VTE were excluded; all patients at the time of admission were free of event. Each person was followed contributing time at risk, from admission to event, discharge or death. VTE incident cases were captured from the Institutional Registry of Thromboembolic Disease (ClinicalTrials.gov Identifier NCT01372514). Incidence rate was calculated with 95% confidence intervals.Results: The crude incidence rate of VTE for clinical patients was 0.49 (95%CI 0.45-0.55) per 1,000 cases person-days, and IR adjusted for WHO was 0.23 (95%CI 0.19-0.26). The crude IR of VTE for surgical patients was 0.25 (95%CI 0.23-0.27), and IR adjusted for WHO was 0.13 (95%CI 0.10-0.17). The incidence rate ratio (IRR) for VTE shows that surgical admission reduces the IRR and age categories increases the thrombosis rate risk, after adjustment for age category, sex and surgical admission.Conclusions: This study suggests that there is a high risk of VTE in hospitalized patients and is still a frequent problem.
publisher Universidad Nacional Cba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología
publishDate 2018
url https://revistas.unc.edu.ar/index.php/med/article/view/17243
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spelling I10-R10-article-172432019-08-20T11:39:08Z Incidence of hospital-acquired venous thromboembolic disease. Incidencia de la enfermedad tromboembolica venosa adquirida en la internación Grande Ratti, María Florencia Posadas-Martínez, María Lourdes Vicens, Jimena González Bernaldo de Quirós, Fernán Vázquez, Fernando Javier Giunta, Diego Hernán epidemiología medicina hospitalaria tromboembolismo venoso epidemiology hospital medicine venous thromboembolism Background: There is limited knowledge of the incidence of venous thromboembolic disease (VTE) during hospitalization, since most of these are community-based data.Purpose: To estimate the incidence rate (IR) of VTE developed during hospitalization.Methods: Prospective cohort of all inpatients admitted in a university tertiary hospital, in Argentina. The inclusion criteria were defined as: adult patients consecutively admitted from July/2006 to August/2013, for any cause. Patients admitted for VTE were excluded; all patients at the time of admission were free of event. Each person was followed contributing time at risk, from admission to event, discharge or death. VTE incident cases were captured from the Institutional Registry of Thromboembolic Disease (ClinicalTrials.gov Identifier NCT01372514). Incidence rate was calculated with 95% confidence intervals.Results: The crude incidence rate of VTE for clinical patients was 0.49 (95%CI 0.45-0.55) per 1,000 cases person-days, and IR adjusted for WHO was 0.23 (95%CI 0.19-0.26). The crude IR of VTE for surgical patients was 0.25 (95%CI 0.23-0.27), and IR adjusted for WHO was 0.13 (95%CI 0.10-0.17). The incidence rate ratio (IRR) for VTE shows that surgical admission reduces the IRR and age categories increases the thrombosis rate risk, after adjustment for age category, sex and surgical admission.Conclusions: This study suggests that there is a high risk of VTE in hospitalized patients and is still a frequent problem. Antecedentes: Existe limitado conocimiento sobre la incidencia de enfermedad tromboembólica venosa (ETV) durante la hospitalización, dado que la mayoría de los son datos basados en la comunidad. Objetivos: Estimar la tasa de incidencia de ETV incidente durante la hospitalización. Material y métodos: Cohorte restrospectiva de todos los pacientes internados en un hospital de alta complejidad, en Argentina. Los criterios de inclusión fueron definidos como: pacientes adultos consecutivamente admitidos entre Julio 2006 y Agosto 2013, por cualquier causa (clínica o quirúrgica). Se excluyeron los pacientes ingresados por ETV, todos los pacientes al momento de la admisión estaban libres del evento. A cada paciente se lo siguió en tiempo de contribución de riesgo, desde la admisión hasta el evento, el alta o la muerte intrahospitalaria. Los casos incidentes de ETV fueron capturados desde el Registro Institucional de Enfermedad Tromboembólica (ClinicalTrials.gov Identifier NCT01372514). La tasa de incidencia se calculó con intervalos de confianza del 95%. Resultados: La tasa de incidencia (TI) cruda de ETV para los pacientes clínicos fue de 0,49 (IC95% 0,45-0,55) por 1.000 pacientes persona-día, y la TI ajustada para la OMS fue de 0,23 (IC95% 0,19-0,26). La TI cruda de ETV para pacientes quirúrgicos fue de 0,25 (IC95% 0,23-0,27), y la TI ajustada para la OMS fue 0,13 (IC95% 0,10-0,17). La razón de tasas de incidencias muestra que la admisión quirúrgica reduce y la edad aumenta el riesgo de trombosis. Conclusiones: Este estudio sugiere que existe un alto riesgo de ETV en pacientes hospitalizados y sigue siendo un problema frecuente. Universidad Nacional Cba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2018-07-27 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf application/vnd.openxmlformats-officedocument.wordprocessingml.document https://revistas.unc.edu.ar/index.php/med/article/view/17243 Revista de la Facultad de Ciencias Médicas de Córdoba.; Vol. 75 No. 2 (2018); 82-87 Revista de la Facultad de Ciencias Médicas de Córdoba; Vol. 75 Núm. 2 (2018); 82-87 Revista da Faculdade de Ciências Médicas de Córdoba; v. 75 n. 2 (2018); 82-87 1853-0605 0014-6722 10.31053/1853.0605.v75.n2 eng https://revistas.unc.edu.ar/index.php/med/article/view/17243/20277 https://revistas.unc.edu.ar/index.php/med/article/view/17243/26545 Derechos de autor 2018 Universidad Nacional de Córdoba

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