Cellular and molecular specificity of pituitary gland physiology

The anterior pituitary gland has the ability to respond to complex signals derived from central and peripheral systems. Perception of these signals and their integration are mediated by cell interactions and cross-talk of multiple signaling transduction pathways and transcriptional regulatory networ...

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Autor principal: Perez-Castro, C.
Otros Autores: Renner, U., Haedo, M.R, Stalla, G.K, Arzt, E.
Formato: Capítulo de libro
Lenguaje:Inglés
Publicado: American Physiological Society 2012
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Acceso en línea:Registro en Scopus
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024 7 |2 cas  |a activin, 114949-22-3; epidermal growth factor receptor, 79079-06-4; estradiol, 50-28-2; gonadotropin, 63231-54-9; prolactin, 12585-34-1, 50647-00-2, 9002-62-4 
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100 1 |a Perez-Castro, C. 
245 1 0 |a Cellular and molecular specificity of pituitary gland physiology 
260 |b American Physiological Society  |c 2012 
270 1 0 |m Arzt, E.; Laboratorio de Fisiología y Biología Molecular, FCEN, UBA, Ciudad Universitaria, 1428 Buenos Aires, Argentina; email: earzt@fbmc.fcen.uba.ar 
506 |2 openaire  |e Política editorial 
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520 3 |a The anterior pituitary gland has the ability to respond to complex signals derived from central and peripheral systems. Perception of these signals and their integration are mediated by cell interactions and cross-talk of multiple signaling transduction pathways and transcriptional regulatory networks that cooperate for hormone secretion, cell plasticity, and ultimately specific pituitary responses that are essential for an appropriate physiological response. We discuss the physiopathological and molecular mechanisms related to this integrative regulatory system of the anterior pituitary gland and how it contributes to modulate the gland functions and impacts on body homeostasis. © 2012 by the American Physiological Society.  |l eng 
593 |a Laboratorio de Regulación de la Expresión Génica en el Crecimiento, Departamento de Quimica Biologica, Departamento de Fisiologia y Biologia Molecular y Celular, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Argentina 
593 |a Max Planck Institute of Psychiatry, Department of Endocrinology, Munich, Germany 
593 |a Instituto de Investigación Biomedicina de Buenos Aires (IBioBA), CONICET, Partner Institute of the Max Planck Society, Buenos Aires, Argentina 
690 1 0 |a ACTIVIN 
690 1 0 |a BONE MORPHOGENETIC PROTEIN 
690 1 0 |a DOPAMINE RECEPTOR STIMULATING AGENT 
690 1 0 |a EPIDERMAL GROWTH FACTOR RECEPTOR 
690 1 0 |a ESTRADIOL 
690 1 0 |a GONADOTROPIN 
690 1 0 |a NOTCH RECEPTOR 
690 1 0 |a PROLACTIN 
690 1 0 |a RETINOID 
690 1 0 |a TRANSCRIPTION FACTOR SOX 
690 1 0 |a TRANSFORMING GROWTH FACTOR BETA 
690 1 0 |a ACTH SECRETING CELL 
690 1 0 |a ADENOHYPOPHYSIS 
690 1 0 |a ADENOMA 
690 1 0 |a ARTICLE 
690 1 0 |a BREAST CANCER 
690 1 0 |a CELL COMMUNICATION 
690 1 0 |a CELL GROWTH 
690 1 0 |a CELL INTERACTION 
690 1 0 |a CELL SPECIFICITY 
690 1 0 |a CELL TYPE 
690 1 0 |a ENDOCRINE CELL 
690 1 0 |a ENDOTHELIUM CELL 
690 1 0 |a GROWTH REGULATION 
690 1 0 |a HORMONE RELEASE 
690 1 0 |a HUMAN 
690 1 0 |a HYPOPHYSIS 
690 1 0 |a HYPOPHYSIS CELL 
690 1 0 |a HYPOPHYSIS TUMOR 
690 1 0 |a LUNG CANCER 
690 1 0 |a MICROGLIA 
690 1 0 |a MOLECULAR BIOLOGY 
690 1 0 |a NEGATIVE FEEDBACK 
690 1 0 |a NEOVASCULARIZATION (PATHOLOGY) 
690 1 0 |a NEUROHYPOPHYSIS 
690 1 0 |a NONHUMAN 
690 1 0 |a ONCOGENE 
690 1 0 |a PARACRINE SIGNALING 
690 1 0 |a PERCEPTION 
690 1 0 |a PERIPHERAL NERVOUS SYSTEM 
690 1 0 |a PLASMACYTOID DENDRITIC CELL 
690 1 0 |a POSITIVE FEEDBACK 
690 1 0 |a PRIORITY JOURNAL 
690 1 0 |a PROLACTIN SECRETING CELL 
690 1 0 |a PROLACTINOMA 
690 1 0 |a PROTEIN EXPRESSION 
690 1 0 |a REGULATORY MECHANISM 
690 1 0 |a SENESCENCE 
690 1 0 |a TSH SECRETING CELL 
650 1 7 |2 spines  |a HOMEOSTASIS 
700 1 |a Renner, U. 
700 1 |a Haedo, M.R. 
700 1 |a Stalla, G.K. 
700 1 |a Arzt, E. 
773 0 |d American Physiological Society, 2012  |g v. 92  |h pp. 1-38  |k n. 1  |p Physiol. Rev.  |x 00319333  |w (AR-BaUEN)CENRE-791  |t Physiological Reviews 
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856 4 0 |u https://doi.org/10.1152/physrev.00003.2011  |y DOI 
856 4 0 |u https://hdl.handle.net/20.500.12110/paper_00319333_v92_n1_p1_PerezCastro  |y Handle 
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