Pesticides used in South American GMO-based agriculture. A review of their effects on humans and animal models

In South America, the incorporation of genetically modified organisms (GMO) engineered to be resistant to pesticides changed the agricultural model into one dependent on the massive use of agrochemicals. Different pesticides are used in response to the demands of the global consuming market to contr...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autor principal: López, S.L
Otros Autores: Aiassa, D., Benítez-Leite, S., Lajmanovich, R., Mañas, F., Poletta, G., Sánchez, N., Simoniello, M.F, Carrasco, A.E
Formato: Capítulo de libro
Lenguaje:Inglés
Publicado: 2012
Materias:
Acceso en línea:Registro en Scopus
DOI
Handle
Registro en la Biblioteca Digital
Aporte de:Registro referencial: Solicitar el recurso aquí
LEADER 45975caa a22032297a 4500
001 PAPER-9396
003 AR-BaUEN
005 20230518203919.0
008 190411s2012 xx ||||fo|||| 00| 0 eng|d
024 7 |2 scopus  |a 2-s2.0-84865377038 
024 7 |2 cas  |a acetylcholinesterase, 9000-81-1; cholinesterase, 9001-08-5; cipermethrin, 52315-07-8; endosulfan, 115-29-7; glyphosate, 1071-83-6; malonaldehyde, 542-78-9; retinoic acid, 302-79-4 
040 |a Scopus  |b spa  |c AR-BaUEN  |d AR-BaUEN 
100 1 |a López, S.L. 
245 1 0 |a Pesticides used in South American GMO-based agriculture. A review of their effects on humans and animal models 
260 |c 2012 
270 1 0 |m Carrasco, A.E.; Laboratorio de Embriología Molecular, Instituto de Biología Celular y Neurociencias, Facultad de Medicina, Universidad de Buenos Aires, Paraguay 2155, 3 piso (1121), Ciudad Autónoma de Buenos Aires, Argentina; email: acarrasco@fmed.uba.ar 
506 |2 openaire  |e Política editorial 
504 |a Teubal, M., Domínguez, D., Sabatino, P., Transformaciones agrarias en la Argentina. Agricultura industrial y sistema agroalimentario (2005) El campo argentino en la encrucijada. Estrategias y resistencias sociales, Ecos en la ciudad, pp. 37-78. , Alianza Editorial, Buenos Aires, N. Giarracca, M. Teubal (Eds.) 
504 |a Teubal, M., Expansión del modelo sojero en la Argentina. De la producción de alimentos a los commodities (2009) La persistencia del campesinado en América Latina, pp. 161-197. , Comunidad de Estudios JAINA, Tarija, P. Lizarraga, C. Vacaflores (Eds.) 
504 |a Palau-Viladesau, T., Cabello, D., Maeyens, A., Rulli, J., Segovia, D., (2007) Los refugiados del modelo agroexportador: impactos del monocultivo de soja en las comunidades campesinas, , BASE IS, Asunción, Paraguay 
504 |a Palau-Viladesau, T., El agronegocio de la soja en Paraguay. Antecedentes e impactos sociales y económicos (2008) Campesinato E Agronegócio Na America Latina: A Questâo Agraria Atual, pp. 18-19. , Expressâo Popular, Sâo Paulo, B. Maņano Fernandez (Ed.) 
504 |a Rojas-Villagra, L., (2009) Actores del agronegocio en Paraguay, , Baseis-Diakonia, Asunción, Paraguay 
504 |a Fogel, R., Efectos ambientales del enclave sojero (2005) Enclave sojero: merma de soberanía y pobreza, pp. 69-70. , Centro de Estudios Rurales Interdisciplinarios, Asunción, Paraguay, R. Fogel, M. Riquelme (Eds.) 
504 |a Walsh, L.P., McCormick, C., Martin, C., Stocco, D.M., Roundup inhibits steroidogenesis by disrupting steroidogenic acute regulatory (StAR) protein expression (2000) Environ. Health Perspect., 108, pp. 769-776 
504 |a Richard, S., Moslemi, S., Sipahutar, H., Benachour, N., Séralini, G.-E., Differential effects of glyphosate and roundup on human placental cells and aromatase (2005) Environ. Health Perspect., 113, pp. 716-720 
504 |a Haefs, R., Schmitz-Eiberger, M., Mainx, H.-G., Mittelstaedt, W., Noga, G., Studies on a new group of biodegradable surfactants for glyphosate (2002) Pest Manag. Sci., 58, pp. 825-833 
504 |a Marc, J., Mulner-Lorillon, O., Boulben, S., Hureau, D., Durand, G., Bellé, R., Pesticide Roundup provokes cell division dysfunction at the level of CDK1/cyclin B activation (2002) Chem. Res. Toxicol., 15, pp. 326-331 
504 |a Benachour, N., Séralini, G.-E., Glyphosate formulations induce apoptosis and necrosis in human umbilical, embryonic, and placental cells (2009) Chem. Res. Toxicol., 22, pp. 97-105 
504 |a Gasnier, C., Dumont, C., Benachour, N., Clair, E., Chagnon, M.C., Séralini, G.-E., Glyphosate-based herbicides are toxic and endocrine disruptors in human cell lines (2009) Toxicology, 262, pp. 184-191 
504 |a Marc, J., Mulner-Lorillon, O., Bellé, R., Glyphosate-based pesticides affect cell cycle regulation (2004) Biol. Cell, 96, pp. 245-249 
504 |a Bellé, R., Le Bouffant, R., Morales, J., Cosson, B., Cormier, P., Mulner-Lorillon, O., Sea urchin embryo, DNA-damaged cell cycle checkpoint and the mechanisms initiating cancer development (2007) J. Soc. Biol., 201, pp. 317-327 
504 |a Marc, J., Bellé, R., Morales, J., Cormier, P., Mulner-Lorillon, O., Formulated glyphosate activates the DNA-response checkpoint of the cell cycle leading to the prevention of G2/M transition (2004) Toxicol. Sci., 82, pp. 436-442 
504 |a Collins, A.R., Dusinska, M., Applications of the comet assay in human biomonitoring (2009) The Comet Assay in Toxicology, pp. 201-227. , RSC Publishing, Cambridge, UK, A. Dhawan, D. Anderson (Eds.) 
504 |a Gollapudi, B.B., Krishna, G., Practical aspects of mutagenicity testing strategy: an industrial perspective (2000) Mutat. Res., 455, pp. 21-28 
504 |a Sarasin, A., An overview of the mechanisms of mutagenesis and carcinogenesis (2003) Mutat. Res., 544, pp. 99-106 
504 |a Schmid, W., The micronucleus test (1975) Mutat. Res., 31, pp. 9-15 
504 |a (1997) Genetic Toxicology: Mammalian Erythrocyte Micronucleus Test, , OECD, Paris, Organisation for Economic Cooperation and Development (OECD) 
504 |a Rojas, E., Lopez, M.C., Valverde, M., Single cell gel electrophoresis assay: methodology and applications (1999) J. Chromatogr. B Biomed. Sci. Appl., 722, pp. 225-254 
504 |a Rahman, M.F., Mahboob, M., Danadevi, K., Saleha Banu, B., Grover, P., Assessment of genotoxic effects of chloropyriphos and acephate by the comet assay in mice leucocytes (2002) Mutat. Res., 516, pp. 139-147 
504 |a Sasaki, Y.F., Sekihashi, K., Izumiyama, F., Nishidate, E., Saga, A., Ishida, K., The comet assay with multiple mouse organs: comparison of comet assay results and carcinogenicity with 208 chemicals selected from the IARC monographs and U.S. NTP Carcinogenicity Database (2000) Crit. Rev. Toxicol., 30, pp. 629-799 
504 |a Garaj-Vrhovac, V., Zeljezic, D., Evaluation of DNA damage in workers occupationally exposed to pesticides using single-cell gel electrophoresis (SCGE) assay. Pesticide genotoxicity revealed by comet assay (2000) Mutat. Res., 469, pp. 279-285 
504 |a Shadnia, S., Azizi, E., Hosseini, R., Khoei, S., Fouladdel, S., Pajoumand, A., Evaluation of oxidative stress and genotoxicity in organophosphorus insecticide formulators (2005) Hum. Exp. Toxicol., 24, pp. 439-445 
504 |a Remor, A.P., Totti, C.C., Moreira, D.A., Dutra, G.P., Heuser, V.D., Boeira, J.M., Occupational exposure of farm workers to pesticides: biochemical parameters and evaluation of genotoxicity (2009) Environ. Int., 35, pp. 273-278 
504 |a U.S.Environmental Protection Agency (EPA) (1993) Office of Prevention, Pesticides and Toxic Substances. Re-registration Eligibility Decision (RED): Glyphosate, , USEPA, Washington, DC 
504 |a Environmental Health Criteria (1994) The Internal Programme on Chemical Safety (IPCS), 159, pp. 84-86. , World Health Organization (WHO), Glyphosate 
504 |a Williams, G.M., Kroes, R., Munro, I.C., Safety evaluation and risk assessment of the herbicide Roundup and its active ingredient, glyphosate, for humans (2000) Regul. Toxicol. Pharmacol., 31, pp. 117-165 
504 |a Mañas, F., Peralta, L., Raviolo, J., García Ovando, H., Weyers, A., Ugnia, L., Genotoxicity of AMPA, the environmental metabolite of glyphosate, assessed by the comet assay and cytogenetic tests (2009) Ecotoxicol. Environ. Saf., 72, pp. 834-837 
504 |a Van de Waart, I., (1995) , Evaluation of the ability of glyphosate to induce chromosome aberrations in cultured peripheral human lymphocytes., , Unpublished report, NOTOX, The Netherlands 
504 |a Lioi, M.B., Scarfi, M.R., Santoro, A., Barbieri, R., Zeni, O., Salvemini, F., Cytogenetic damage and induction of pro-oxidant state in human lymphocytes exposed in vitro to gliphosate, vinclozolin, atrazine, and DPX-E9636 (1998) Environ. Mol. Mutagen., 32, pp. 39-46 
504 |a Monroy, C.M., Cortés, A.C., Sicard, D.M., Groot de Restrepo, H., Citotoxicidad y genotoxicidad en células humanas expuestas in vitro a glifosato/cytotoxicity and genotoxicity of human cells exposed in vitro to glyphosate (2005) Biomedica, 25, pp. 335-345 
504 |a Mañas, F., Peralta, L., Raviolo, J., Ovando, H.G., Weyers, A., Ugnia, L., Genotoxicity of glyphosate assessed by the comet assay and cytogenetic tests (2009) Environ. Toxicol. Pharmacol., 28, pp. 37-41 
504 |a Bolognesi, C., Genotoxicity of pesticides: a review of human biomonitoring studies (2003) Mutat. Res., 543, pp. 251-272 
504 |a Mañas Torres, F., Gonźlez Cid Uroz, M.B., García Ovando, H., Weyers Anchordoqui, I., Ugnia Vera, L., Larripa Hand, I.B., Evaluation of genotoxicity of the herbicide glyphosate quantitatively measured by the comet assay and micronucleus formation in treated mice (2006) Theoria, 15, pp. 53-60 
504 |a IARC Monographs on the Evaluation of the Carcinogenic Risks to Humans Supplement 7 (1987) Overall Evaluations of Carcinogenicity: An Updating of IARC Monographs Volumes 1 to 42., , Lyon, IARC, International Agency for Research on Cancer, WHO, WHO 
504 |a Dearfield, K.L., McCarroll, N.E., Protzel, A., Stack, H.F., Jackson, M.A., Waters, M.D., A survey of EPA/OPP and open literature on selected pesticide chemicals. II. Mutagenicity and carcinogenicity of selected chloroacetanilides and related compounds (1999) Mutat. Res., 443, pp. 183-221 
504 |a Alavanja, M.C., Sandler, D.P., McMaster, S.B., Zahm, S.H., McDonnell, C.J., Lynch, C.F., The agricultural health study (1996) Environ. Health Perspect., 104, pp. 362-369 
504 |a Kohen, R., Nyska, A., Oxidation of biological systems: oxidative stress phenomena, antioxidants, redox reactions, and methods for their quantification (2002) Toxicol. Pathol., 30, pp. 620-650 
504 |a Pastor Benito, S., (2002) Biomonitorización citogenética de cuatro poblaciones agrícolas europeas, expuestas a agroquímicos, mediante el ensayo de micronúcleos. Tesis doctoral., Departament de Genética i de Microbiología. Grup de mutagenei, , Universitat Autónoma de Barcelona, Facultat de Ciencias 
504 |a Ergene, S., Celik, A., Cavaş, T., Kaya, F., Genotoxic biomonitoring study of population residing in pesticide contaminated regions in G̈ksu Delta: micronucleus, chromosomal aberrations and sister chromatid exchanges (2007) Environ. Int., 33, pp. 877-885 
504 |a Gómez-Arroyo, S., Díaz-Śnchez, Y., Meneses-Pérez, M.A., Villalobos-Pietrini, R., De León-Rodríguez, J., Cytogenetic biomonitoring in a Mexican floriculture worker group exposed to pesticides (2000) Mutat. Res., 466, pp. 117-124 
504 |a Ascarrunz, M.E., Tirado, N., Gonźles, A.R., Cuti, M., Cervantes, R., Huici, O., Evaluación de riesgo genotóxico: biomonitorización de trabajadores agrícolas de Caranavi, Guainay, Palca, Mecapaca expuestos a agroquímicos (2006) Cuadernos Del Hospital De Clínicas., 51, pp. 7-18 
504 |a Paz-y-Miño, C., Arévalo, M., Sanchez, M.E., Leone, P.E., Chromosome and DNA damage analysis in individuals occupationally exposed to pesticides with relation to genetic polymorphism for CYP 1A1 gene in Ecuador (2004) Mutat. Res., 562, pp. 77-89 
504 |a Mañas, F., Peralta, L., Gorla, N., Bosh, B., Aiassa, D., Chromosomal aberrations in workers occupationally exposed to pesticides in Córdoba (2009) J. Basis Appl. Genet., 20, pp. 9-13 
504 |a Simoniello, M.F., Kleinsorge, E.C., Scagnetti, J.A., Grigolato, R.A., Poletta, G.L., Carballo, M.A., DNA damage in workers occupationally exposed to pesticide mixtures (2008) J. Appl. Toxicol., 28, pp. 957-965 
504 |a Simoniello, M.F., Kleinsorge, E.C., Scagnetti, J.A., Mastandrea, C., Grigolato, R.A., Paonessa, A.M., Biomarkers of cellular reaction to pesticide exposure in a rural population (2010) Biomarkers, 15, pp. 52-60 
504 |a McCauley, L.A., Anger, W.K., Keifer, M., Langley, R., Robson, M.G., Rohlman, D., Studying health outcomes in farmworker populations exposed to pesticides (2006) Environ. Health Perspect., 114, pp. 953-960 
504 |a Ranjbar, A., Pasalar, P., Abdollahi, M., Induction of oxidative stress and acetylcholinesterase inhibition in organophosphorous pesticide manufacturing workers (2002) Hum. Exp. Toxicol., 21, pp. 179-182 
504 |a Singh, V.K., Jyoti, M.M.K., Reddy, C., Kesavachandran, S.K., Rastogi, M.K.J., Siddiqui, Biomonitoring of organochlorines, glutathione, lipid peroxidation and cholinesterase activity among pesticide sprayers in mango orchards (2007) Clin. Chim. Acta, 377, pp. 268-272 
504 |a Banerjee, B.D., Seth, V., Bhattacharya, A., Pasha, S.T., Chakraborty, A.K., Biochemical effects of some pesticides on lipid peroxidation and free-radical scavengers (1999) Toxicol. Lett., 107, pp. 33-47 
504 |a Prakasam, A., Sethupathy, S., Lalitha, S., Plasma and RBCs antioxidant status in occupational male pesticide sprayers (2001) Clin. Chim. Acta, 310, pp. 107-112 
504 |a Kale, M., Rathore, N., John, S., Bhatnagar, D., Lipid peroxidative damage on pyrethroid exposure and alterations in antioxidant status in rat erythrocytes: a possible involvement of reactive oxygen species (1999) Toxicol. Lett., 105, pp. 197-205 
504 |a Gultekin, F., Ozturk, M., Akdogan, M., The effect of organophosphate insecticide chlorpyrifos-ethyl on lipid peroxidation and antioxidant enzymes (in vitro) (2000) Arch. Toxicol., 74, pp. 533-538 
504 |a Gabbianelli, R., Falcioni, G., Nasuti, C., Cantalamessa, F., Cypermethrin-induced plasma membrane perturbation on erythrocytes from rats: reduction of fluidity in the hydrophobic core and in glutathione peroxidase activity (2002) Toxicology, 175, pp. 91-101 
504 |a Altuntas, I., Delibas, N., Doguc, D.K., Ozmen, S., Gultekin, F., Role of reactive oxygen species in organophosphate insecticide phosalone toxicity in erythrocytes in vitro (2003) Toxicolol. In Vitro, 17, pp. 153-157 
504 |a Nasuti, C., Cantalamessa, F., Falcioni, G., Gabbianelli, R., Different effects of Type I and Type II pyrethroids on erythrocyte plasma membrane properties and enzymatic activity in rats (2003) Toxicology, 191, pp. 233-244 
504 |a Karademir Catalgol, B., Ozden, S., Alpertunga, B., Effects of trichlorfon on malondialdehyde and antioxidant system in human erythrocytes (2007) Toxicol. In Vitro, 21, pp. 1538-1544 
504 |a Akhgari, M., Abdollahi, M., Kebryaeezadeh, A., Hosseini, R., Sabzevari, O., Biochemical evidence for free radical-induced lipid peroxidation as a mechanism for subchronic toxicity of malathion in blood and liver of rats (2003) Hum. Exp. Toxicol., 22, pp. 205-211 
504 |a Cicchetti, R., Argentin, G., The role of oxidative stress in the in vitro induction of micronuclei by pesticides in mouse lung fibroblasts (2003) Mutagenesis, 18, pp. 127-132 
504 |a Collins, A.R., Oxidative DNA damage, antioxidants, and cancer (1999) Bioessays, 21, pp. 238-246 
504 |a De Marco, A., De Salvia, R., Polani, S., Ricordy, R., Sorrenti, F., Perticone, P., Evaluation of genotoxic and cytotoxic properties of pesticides employed in Italian agricultural practices (2000) Environ. Res., 83, pp. 311-321 
504 |a Castillo-Cadena, J., Tenorio-Vieyra, L.E., Quintana-Carabia, A.I., García-Fabila, M.M., Juan, E.R.-S., Madrigal-Bujaidar, E., Determination of DNA damage in floriculturists exposed to mixtures of pesticides (2006) J. Biomed. Biotechnol., 2006, p. 97896 
504 |a Benítez-leite, S., Macchi, M.L., Acosta, M., Malformaciones congénitas asociadas a agrotóxicos (2009) Arch. Pediatr. Urug., 80, pp. 237-247 
504 |a Regidor, E., Ronda, E., García, A.M., Domínguez, V., Paternal exposure to agricultural pesticides and cause specific fetal death (2004) Occup. Environ. Med., 61, pp. 334-339 
504 |a Pastore, L.M., Hertz-Picciotto, I., Beaumont, J.J., Risk of stillbirth from occupational and residential exposures (1997) Occup. Environ. Med., 54, pp. 511-518 
504 |a Bell, E.M., Hertz-Picciotto, I., Beaumont, J.J., A case-control study of pesticides and fetal death due to congenital anomalies (2001) Epidemiology, 12, pp. 148-156 
504 |a Winchester, P.D., Huskins, J., Ying, J., Agrichemicals in surface water and birth defects in the United States (2009) Acta Paediatr., 98, pp. 664-669 
504 |a Ministerio de Salud Pública y Bienestar social. Secretaria del Ambiente de Paraguay. OPS/OMS, Informe de la inspección de la F́brica " Chemtec SAE," (2009) Asunción 
504 |a Benítez-Leite, S., Macchi, M.L., Ferńndez, V., Franco, D., Ea, F., Mojoli, A., Daño celular en una población infantil potencialmente expuesta a pesticidas/cell damage in a pediatric population potentially exposed to pesticides (2010) Pediatría (Asunción), 37, pp. 97-106 
504 |a Bull, S., Fletcher, K., Boobis, A.R., Battershill, J.M., Evidence for genotoxicity of pesticides in pesticide applicators: a review (2006) Mutagenesis, 21, pp. 93-103 
504 |a Hughes, I., Woods, H.F., (2002) Risk Assessment of Mixtures of Pesticides and Similar Substances. Committee on Toxicity of Chemicals in Food, Consumer Products and the Environment, , Food Standards Agency, UK 
504 |a Lorenzatti, E., Maitre, M., Lenardón, A., Lajmanovich, R., Peltzer, P., Anglada, M., Pesticide residues in immature soybean in Argentina croplands (2004) Fresen. Environ. Bull., 13, pp. 675-678 
504 |a Peltzer, P.M., Lajmanovich, R.C., Amphibians (2007) The Middle Parana River: Limnology of a Subtropical Wetland, pp. 327-340. , Springer, Berlin, Heidelberg, New York, M.H. Iriondo, J.C. Paggi, M.J. Parma (Eds.) 
504 |a Jergentz, S., Mugni, H., Bonetto, C., Schulz, R., Assessment of insecticide contamination in runoff and stream water of small agricultural streams in the main soybean area of Argentina (2005) Chemosphere, 61, pp. 817-826 
504 |a Peruzzo, P.J., Porta, A.A., Ronco, A.E., Levels of glyphosate in surface waters, sediments and soils associated with direct sowing soybean cultivation in north pampasic region of Argentina (2008) Environmental Pollution (Barking Essex: 1987), 156, pp. 61-66 
504 |a Peltzer, P.M., Lajmanovich, R.C., Śnchez-Hernandez, J.C., Cabagna, M.C., Attademo, A.M., Bassó, A., Effects of agricultural pond eutrophication on survival and health status of Scinax nasicus tadpoles (2008) Ecotoxicol. Environ. Saf., 70, pp. 185-197 
504 |a Lajmanovich, R.C., Śnchez-Herńndez, J.C., Stringhini, G., Peltzer, P.M., Levels of serum cholinesterase activity in the rococo toad (Bufo paracnemis) in agrosystems of Argentina (2004) Bull. Environ. Contam. Toxicol., 72, pp. 586-591 
504 |a Lajmanovich, R.C., Śnchez-Herńndez, J.C., Peltzer, P.M., Attademo, A.M., Fiorenza, G.S., Cabagna, M.C., Levels of plasma B-esterases and glutathione-S-transferase activities in three South American toad species (2008) Toxicol. Environ. Chem., 90, pp. 1145-1161 
504 |a Attademo, A.M., Peltzer, P.M., Lajmanovich, R.C., Cabagna, M., Fiorenza, G., Plasma B-esterase and glutathione S-transferase activity in the toad Chaunus schneideri (Amphibia, Anura) inhabiting rice agroecosystems of Argentina (2007) Ecotoxicology, 16, pp. 533-539 
504 |a Attademo, A.M., Cabagna-Zenklusen, M., Lajmanovich, R.C., Peltzer, P.M., Junges, C., Bassó, A., B-esterase activities and blood cell morphology in the frog Leptodactylus chaquensis (Amphibia: Leptodactylidae) on rice agroecosystems from Santa Fe Province (Argentina) (2011) Ecotoxicology, 20, pp. 274-282 
504 |a Śnchez, L.C., (2011) Alterations of the dynamics and reproductive biology of anurans (Amphibia, Anura) produced by the advance of the agricultural border in natural environments of the upper delta of the Parań River. Doctoral thesis, , Universidad Nacional del Litoral, Facultad de Bioquímica y Ciencias Biológicas 
504 |a Peltzer, P.M., Lajmanovich, R.C., Beltzer, A.H., The effects of habitat fragmentation on amphibian species richness in the floodplain of the middle Parań River (2003) Herpetol. J., 13, pp. 95-98 
504 |a Peltzer, P.M., Lajmanovich, R.C., Attademo, A.M., Beltzer, A.H., Diversity of anurans across agricultural ponds in argentina (2006) Biodivers. Conserv., 15, pp. 3499-3513 
504 |a Peltzer, P.M., Lajmanovich, R.C., Śnchez, L.C., Attademo, A.M., Junges, C.M., Bionda, C.L., Morphological abnormalities in amphibian populations from the mid-eastern region of Argentina (2011) Herpetol. Conserv. Biol., 6, pp. 432-442 
504 |a Izaguirre, M.F., Lajmanovich, R.C., Peltzer, P.M., Peralta Soler, A., Casco, V.H., Cypermethrin-induced apoptosis in the telencephalon of Physalaemus biligonigerus tadpoles (Anura: Leptodactylidae) (2000) Bull. Environ. Contam. Toxicol., 65, pp. 501-507 
504 |a Izaguirre, F., Lajmanovich, R., Peltzer, P., Peralta-Soler, A., Casco, V., Induction of cell death by the sintethic pyrethroid insecticide cypermethrin in the developing brain of Physalaemus biligonigerus tadpoles from Argentina (2001) FROGLOG, 43, p. 2 
504 |a Casco, V.H., Izaguirre, M.F., Marín, L., Vergara, M.N., Lajmanovich, R.C., Peltzer, P., Apoptotic cell death in the central nervous system of Bufo arenarum tadpoles induced by cypermethrin (2006) Cell Biol. Toxicol., 22, pp. 199-211 
504 |a The European Agency for the Evaluation of Medicinal Products, EMEA/MRL/876/03-FINAL Veterinary Medicines and Inspections (2003) Cypermethrin Summary Report 3 
504 |a Cabagna, M.C., Lajmanovich, R.C., Peltzer, P.M., Attademo, A.M., Ale, E., Induction of micronuclei in tadpoles of Odontophrynus americanus (Amphibia: Leptodactylidae) by the pyrethroid insecticide cypermethrin (2006) Toxicol. Environ. Chem., 88, pp. 729-737 
504 |a Lajmanovich, R., Lorenzatti, E., De la Sierra, P., Marino, F., Stringhini, G., Peltzer, P., Reduction in the mortality of tadpoles (Physalaemus biligonigerus, Amphibia: Leptodactylidae) exposed to cypermethrin: uptake by aquatic ferns (2003) Fresen. Environ. Bull., 12, pp. 1558-1561 
504 |a (2010) Stockholm Convention on Persistent Organic Pollutants-Conference of the Parties of the Stockholm Convention on Persistent Organic Pollutants, , Geneva, United Nations Environment Programme (UNEP) 
504 |a Lenardón, A., Maitre de Hevia, M.I., Enrique de Carbone, S., Organochlorine pesticides in Argentinian butter (1994) Sci. Total Environ., 144, pp. 273-277 
504 |a Maitre, M.I., de la Sierra, P., Lenardon, A., Enrique, S., Marino, F., Pesticide residue levels in Argentinian pasteurised milk (1994) Sci. Total Environ., 155, pp. 105-108 
504 |a Lajmanovich, R.C., Lorenzatti, E., De la Sierra, P., Marino, F., Peltzer, P.M., First Registrations of Organochlorines Pesticides Residues in Amphibians of the Mesopotamic Region, Argentina (2002) FROGLOG, 54, p. 4 
504 |a Lajmanovich, R., De la sierra, P., Marino, F., Peltzer, P., Lenardón, A., Lorenzatti, E., Determinación de residuos de organoclorados en vertebrados silvestres del litoral fluvial de Argentina (2005) Temas de la biodiversidad del litoral fluvial argentino II. Misceĺnea, pp. 255-262. , INSUGEO, Tucuḿn 
504 |a Stoker, C., Repetti, M.R., García, S.R., Zayas, M.A., Galoppo, G.H., Beldoménico, H.R., Organochlorine compound residues in the eggs of broad-snouted caimans (Caiman latirostris) and correlation with measures of reproductive performance (2011) Chemosphere, 84, pp. 311-317 
504 |a Subsecretaria de Recursos Hídricos de la Nación. República Argentina, Niveles Guía Nacionales de Calidad de Agua Ambiente Correspondiente a Endosulf́n (2004) NGNCA, p. 18 
504 |a Lajmanovich, R.C., Cabagna, M., Peltzer, P.M., Stringhini, G.A., Attademo, A.M., Micronucleus induction in erythrocytes of the Hyla pulchella tadpoles (Amphibia: Hylidae) exposed to insecticide endosulfan (2005) Mutat. Res., 587, pp. 67-72 
504 |a Govindarajulu, P.P., (2008) Literature review of impacts of glyphosate herbicide on amphibians: what risks can the silvicultural use of this herbicide pose for amphibians in B. C.?, , B. C. Ministry of Environment, Victoria, BC., Wildlife Report. No. R-28 
504 |a Lajmanovich, R.C., Sandoval, M.T., Peltzer, P.M., Induction of mortality and malformation in Scinax nasicus tadpoles exposed to glyphosate formulations (2003) Bull. Environ. Contam. Toxicol., 70, pp. 612-618 
504 |a Lajmanovich, R., Lorenzatti, E., Maitre, M.I., Enrique, S., Peltzer, P., Comparative acute toxicity of the commercial herbicides glyphosate to neotropical tadpoles Scinax nasicus (Anura: Hylidae) (2003) Fresen. Environ. Bull., 12, pp. 364-367 
504 |a Lajmanovich, R.C., Attademo, A.M., Peltzer, P.M., Junges, C.M., Cabagna, M.C., Toxicity of four herbicide formulations with glyphosate on Rhinella arenarum (anura: bufonidae) tadpoles: B-esterases and glutathione S-transferase inhibitors (2011) Arch. Environ. Contam. Toxicol., 60, pp. 681-689 
504 |a Mann, R.M., Bidwell, J.R., The toxicity of glyphosate and several glyphosate formulations to four species of southwestern Australian frogs (1999) Arch. Environ. Contam. Toxicol., 36, pp. 193-199 
504 |a Paganelli, A., Gnazzo, V., Acosta, H., Loópez, S.L., Carrasco, A.E., Glyphosate-based herbicides produce teratogenic effects on vertebrates by impairing retinoic acid signaling (2010) Chem. Res. Toxicol., 23, pp. 1586-1595 
504 |a Sulik, K.K., Cook, C.S., Webster, W.S., Teratogens and craniofacial malformations: relationships to cell death (1988) Development, 103 (SUPPL.), pp. 213-231 
504 |a Clotman, F., van Maele-Fabry, G., Chu-Wu, L., Picard, J.J., Structural and gene expression abnormalities induced by retinoic acid in the forebrain (1998) Reprod. Toxicol., 12, pp. 169-176 
504 |a Franco, P.G., Paganelli, A.R., López, S.L., Carrasco, A.E., Functional association of retinoic acid and hedgehog signaling in Xenopus primary neurogenesis (1999) Development, 126, pp. 4257-4265 
504 |a Sharpe, C., Goldstone, K., Retinoid signalling acts during the gastrula stages to promote primary neurogenesis (2000) Int. J. Dev. Biol., 44, pp. 463-470 
504 |a Chiang, C., Litingtung, Y., Lee, E., Young, K.E., Corden, J.L., Westphal, H., Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function (1996) Nature, 383, pp. 407-413 
504 |a Roessler, E., Belloni, E., Gaudenz, K., Jay, P., Berta, P., Scherer, S.W., Mutations in the human Sonic Hedgehog gene cause holoprosencephaly (1996) Nat. Genet., 14, pp. 357-360 
504 |a Jeong, J., Mao, J., Tenzen, T., Kottmann, A.H., McMahon, A.P., Hedgehog signaling in the neural crest cells regulates the patterning and growth of facial primordia (2004) Genes Dev., 18, pp. 937-951 
504 |a Le Douarin, N.M., Halpern, M.E., Discussion point. Origin and specification of the neural tube floor plate: insights from the chick and zebrafish (2000) Curr. Opin. Neurobiol., 10, pp. 23-30 
504 |a Charrier, J.B., Lapointe, F., Le Douarin, N.M., Teillet, M.A., Anti-apoptotic role of Sonic hedgehog protein at the early stages of nervous system organogenesis (2001) Development, 128, pp. 4011-4020 
504 |a Britto, J., Tannahill, D., Keynes, R., A critical role for sonic hedgehog signaling in the early expansion of the developing brain (2002) Nat. Neurosci., 5, pp. 103-110 
504 |a Matsuo, I., Kuratani, S., Kimura, C., Takeda, N., Aizawa, S., Mouse Otx2 functions in the formation and patterning of rostral head (1995) Genes Dev., 9, pp. 2646-2658 
504 |a Kimura, C., Takeda, N., Suzuki, M., Oshimura, M., Aizawa, S., Matsuo, I., Cis-acting elements conserved between mouse and pufferfish Otx2 genes govern the expression in mesencephalic neural crest cells (1997) Development, 124, pp. 3929-3941 
504 |a Erlich, M.S., Cunningham, M.L., Hudgins, L., Transmission of the dysgnathia complex from mother to daughter (2000) Am. J. Med. Genet., 95, pp. 269-274 
504 |a Geng, X., Oliver, G., Pathogenesis of holoprosencephaly (2009) J. Clin. Invest., 119, pp. 1403-1413 
504 |a Lipinski, R.J., Godvin, A., O'leary-Moore, S.K., Parnell, S.E., Sulik, K.K., Genesis of teratogen-induced holoprosencephaly in mice (2010) Am. J. Med. Genet. C Semin. Med. Genet, 154 C, pp. 29-42 
504 |a Lammer, E.J., Chen, D.T., Hoar, R.M., Agnish, N.D., Benke, P.J., Braun, J.T., Retinoic acid embryopathy (1985) N. Engl. J. Med., 313, pp. 837-841 
504 |a Durston, A.J., Timmermans, J.P., Hage, W.J., Hendriks, H.F., de Vries, N.J., Heideveld, M., Retinoic acid causes an anteroposterior transformation in the developing central nervous system (1989) Nature, 340, pp. 140-144 
504 |a López, S.L., Carrasco, A.E., Retinoic acid induces changes in the localization of homeobox proteins in the antero-posterior axis of Xenopus laevis embryos (1992) Mech. Dev., 36, pp. 153-164 
504 |a López, S.L., Dono, R., Zeller, R., Carrasco, A.E., Differential effects of retinoic acid and a retinoid antagonist on the spatial distribution of the homeoprotein Hoxb-7 in vertebrate embryos (1995) Dev. Dyn., 204, pp. 457-471 
504 |a Clotman, F., Van Maele-Fabry, G., Picard, J.J., Retinoic acid induces a tissue-specific deletion in the expression domain of Otx2 (1997) Neurotoxicol. Teratol., 19, pp. 163-169 
504 |a Padmanabhan, R., Retinoic acid-induced caudal regression syndrome in the mouse fetus (1998) Reprod. Toxicol., 12, pp. 139-151 
504 |a Chen, Y., Huang, L., Solursh, M., A concentration gradient of retinoids in the early Xenopus laevis embryo (1994) Dev. Biol., 161, pp. 70-76 
504 |a Godsave, S.F., Koster, C.H., Getahun, A., Mathu, M., Hooiveld, M., van der Wees, J., Graded retinoid responses in the developing hindbrain (1998) Dev. Dyn., 213, pp. 39-49 
504 |a Marsh-Armstrong, N., McCaffery, P., Hyatt, G., Alonso, L., Dowling, J.E., Gilbert, W., Retinoic acid in the anteroposterior patterning of the zebrafish trunk (1995) Roux's Arch. Dev. Biol., 205, pp. 103-113 
504 |a Grandel, H., Lun, K., Rauch, G.-J., Rhinn, M., Piotrowski, T., Houart, C., Retinoic acid signalling in the zebrafish embryo is necessary during pre-segmentation stages to pattern the anterior-posterior axis of the CNS and to induce a pectoral fin bud (2002) Development, 129, pp. 2851-2865 
504 |a Dobbs-McAuliffe, B., Zhao, Q., Linney, E., Feedback mechanisms regulate retinoic acid production and degradation in the zebrafish embryo (2004) Mech. Dev., 121, pp. 339-350 
504 |a Maden, M., The role of retinoic acid in embryonic and post-embryonic development (2000) Proc. Nutr. Soc., 59, pp. 65-73 
504 |a Berggren, K., McCaffery, P., Dräger, U., Forehand, C.J., Differential distribution of retinoic acid synthesis in the chicken embryo as determined by immunolocalization of the retinoic acid synthetic enzyme, RALDH-2 (1999) Dev. Biol., 210, pp. 288-304 
504 |a Chen, Y., Huang, L., Russo, A.F., Solursh, M., Retinoic acid is enriched in Hensen's node and is developmentally regulated in the early chicken embryo (1992) Proc. Natl. Acad. Sci. U.S.A., 89, pp. 10056-10059 
504 |a Ang, H.L., Deltour, L., Hayamizu, T.F., Zgombić-Knight, M., Duester, G., Retinoic acid synthesis in mouse embryos during gastrulation and craniofacial development linked to class IV alcohol dehydrogenase gene expression (1996) J. Biol. Chem., 271, pp. 9526-9534 
504 |a de Roos, K., Sonneveld, E., Compaan, B., ten Berge, D., Durston, A.J., van der Saag, P.T., Expression of retinoic acid 4-hydroxylase (CYP26) during mouse and Xenopus laevis embryogenesis (1999) Mech. Dev., 82, pp. 205-211 
504 |a Maden, M., Sonneveld, E., van der Saag, P.T., Gale, E., The distribution of endogenous retinoic acid in the chick embryo: implications for developmental mechanisms (1998) Development, 125, pp. 4133-4144 
504 |a Sakai, Y., Meno, C., Fujii, H., Nishino, J., Shiratori, H., Saijoh, Y., The retinoic acid-inactivating enzyme CYP26 is essential for establishing an uneven distribution of retinoic acid along the anterio-posterior axis within the mouse embryo (2001) Genes Dev., 15, pp. 213-225 
504 |a Gongal, P.A., Waskiewicz, A.J., Zebrafish model of holoprosencephaly demonstrates a key role for TGIF in regulating retinoic acid metabolism (2008) Hum. Mol. Genet., 17, pp. 525-538 
504 |a Hernandez, R.E., Putzke, A.P., Myers, J.P., Margaretha, L., Moens, C.B., Cyp26 enzymes generate the retinoic acid response pattern necessary for hindbrain development (2007) Development, 134, pp. 177-187 
504 |a Reijntjes, S., Rodaway, A., Maden, M., The retinoic acid metabolising gene, CYP26B1, patterns the cartilaginous cranial neural crest in zebrafish (2007) Int. J. Dev. Biol., 51, pp. 351-360 
504 |a Duester, G., Retinoic acid synthesis and signaling during early organogenesis (2008) Cell, 134, pp. 921-931 
504 |a Niederreither, K., Dollé, P., Retinoic acid in development: towards an integrated view (2008) Nat. Rev. Genet., 9, pp. 541-553 
504 |a Dallegrave, E., Mantese, F.D., Coelho, R.S., Pereira, J.D., Dalsenter, P.R., Langeloh, A., The teratogenic potential of the herbicide glyphosate-Roundup in Wistar rats (2003) Toxicol. Lett., 142, pp. 45-52 
504 |a Alappat, S., Zhang, Z.Y., Chen, Y.P., Msx homeobox gene family and craniofacial development (2003) Cell Res., 13, pp. 429-442 
504 |a Kessel, M., Respecification of vertebral identities by retinoic acid (1992) Development, 115, pp. 487-501 
504 |a Campaña, H., Pawluk, M.S., López Camelo, J.S., Grupo de Estudio ECLAMC, Births prevalence of 27 selected congenital anomalies in 7 geographic regions of Argentina (2010) Arch. Argent. Pediatr., 108, pp. 409-417 
504 |a Comisión Investigadora de contaminantes del agua de la Provincia del Chaco (2010) Informe de la Comisión Investigadora de contaminantes del agua de la Provincia del Chaco, , Resistencia, Chaco., Argentina 
504 |a Saldarriaga, W., Epidemiological surveillance of cyclopia in the Hospital Universitario del Valle, Cali, Colombia 2004-2008 (2010) Revista Colombiana De Obstetricia Y Ginecología, 61, pp. 12-17 
504 |a Gilbert, S., (2010) Developmental Biology, , Sinauer Associates, Inc., Sunderland, MA 
504 |a Poulsen, M.S., Rytting, E., Mose, T., Knudsen, L.E., Modeling placental transport: correlation of in vitro BeWo cell permeability and ex vivo human placental perfusion (2009) Toxicol. In Vitro, 23, pp. 1380-1386 
504 |a Anadón, A., Martínez-Larrañaga, M.R., Martínez, M.A., Castellano, V.J., Martínez, M., Martin, M.T., Toxicokinetics of glyphosate and its metabolite aminomethyl phosphonic acid in rats (2009) Toxicol. Lett., 190, pp. 91-95 
504 |a Larriera, A., Imhof, A., Siroski, P., Estado actual de los programas de conservación y manejo del género Caiman en Argentina (2008) Contribución al conocimiento del género Caiman de Suramérica, pp. 139-179. , Public. Asoc. Amigos de Doña Ana 18, Sevilla, España, J. Castroviejo, J. Ayarzaguena, A. Velasco (Eds.) 
504 |a Poletta, G.L., Larriera, A., Siroski, P., Kleinsorge, E., Mudry, M.D., Integral approach of Glyphosate-induced alterations in a South American caiman species (2011) Herbicides: Properties, Crop Protection and Environmental Hazards, , Nova Science Publishers, Inc., New York, USA, K.D. Piotrowski (Ed.) 
504 |a Poletta, G.L., Larriera, A., Kleinsorge, E., Mudry, M.D., Caiman latirostris (broad-snouted caiman) as a sentinel organism for genotoxic monitoring: basal values determination of micronucleus and comet assay (2008) Mutat. Res., 650, pp. 202-209 
504 |a Poletta, G.L., Larriera, A., Kleinsorge, E., Mudry, M.D., Genotoxicity of the herbicide formulation Roundup (glyphosate) in broad-snouted caiman (Caiman latirostris) evidenced by the Comet assay and the Micronucleus test (2009) Mutat. Res., 672, pp. 95-102 
504 |a Poletta, G.L., Kleinsorge, E., Paonessa, A., Mudry, M.D., Larriera, A., Siroski, P.A., Genetic, enzymatic and developmental alterations observed in Caiman latirostris exposed in ovo to pesticide formulations and mixtures in an experiment simulating environmental exposure (2011) Ecotoxicol. Environ. Saf., 74, pp. 852-859 
504 |a Pickett, S.T.A., White, P.S., (1985) The ecology of natural disturbance and patch dynamics, , Academic Press, San Diego, CA 
504 |a De Bach, P., Rosen, D., (1974) Biological control by natural enemies, , Cambridge University Press, Cambridge, UK 
504 |a Levins, R., Perspectives in integrated pest management: from an industrial to ecological model of pest management (1986) Ecological Theory and Integrated Pest Management Practice, , Wiley & Sons, USA, M. Kogan, P. Jepson (Eds.) 
504 |a Minervino, E.V., (1996) Estudio biológico y bioecológico de arañas depredadoras de plagas de la soja., , Doctoral thesis, Universidad Nacional de La Plata 
504 |a Liljesthröm, G.G., Selectividad del parasitoide Trichopoda giacomellii (Blanchard) (Diptera: Tachinidae) hacia individuos de Nezara viridula (L.) (Hemiptera: Pentatomidae) que difieren en el estado de desarrollo, sexo, edad y patrones de coloración (1991) Ecología Austral, 1, pp. 41-49 
504 |a Luna, M.G., Śnchez, N.E., Parasitoid assemblages of soybean defoliator Lepidoptera in north-western Buenos Aires province, Argentina (1999) Agric. Forest Entomol., 1, pp. 255-260 
504 |a Liljesthröm, G.G., Bernstein, C., Density dependence and regulation in the system: Nezara viridula (L.) (Hemiptera: Pentatomidae), host and Trichopoda giacomellii (Blanchard) (Diptera: Tachinidae), parasitoid (1990) Oecologia, 84, pp. 45-52 
504 |a Liljesthröm, G.G., Rabinovich, J., Modeling biological control: the population regulation of Nezara viridula by the parasitoid Trichopoda giacomellii (2004) Ecol. Appl., 14, pp. 254-267 
504 |a Schneider, M.I., Śnchez, N., Pineda, S., Chi, H., Ronco, A., Impact of glyphosate on the development, fertility and demography of Chrysoperla externa (Neuroptera: Chrysopidae): ecological approach (2009) Chemosphere, 76, pp. 1451-1455 
504 |a Benamú, M.A., Schneider, M.I., Śnchez, N.E., Effects of the herbicide glyphosate on biological attributes of Alpaida veniliae (Araneae, Araneidae), in laboratory (2010) Chemosphere, 78, pp. 871-876 
504 |a Letourneau, D.K., Conservation biology: lessons for conservation natural enemies (1998) Conservation Biological Control, , Academic Press, USA, P. Barbosa (Ed.) 
504 |a Papis, E., Bernardini, G., Gornati, R., Menegola, E., Prati, M., Gene expression in Xenopus laevis embryos after Triadimefon exposure (2007) Gene Expr. Patterns, 7, pp. 137-142 
504 |a Davey, J.C., Nomikos, A.P., Wungjiranirun, M., Sherman, J.R., Ingram, L., Batki, C., Arsenic as an endocrine disruptor: arsenic disrupts retinoic acid receptor-and thyroid hormone receptor-mediated gene regulation and thyroid hormone-mediated amphibian tail metamorphosis (2008) Environ. Health Perspect., 116, pp. 165-172 
504 |a Lenkowski, J.R., Reed, J.M., Deininger, L., McLaughlin, K.A., Perturbation of organogenesis by the herbicide atrazine in the amphibian Xenopus laevis (2008) Environ. Health Perspect., 116, pp. 223-230 
504 |a Lenkowski, J.R., McLaughlin, K.A., Acute atrazine exposure disrupts matrix metalloproteinases and retinoid signaling during organ morphogenesis in Xenopus laevis (2010) J. Appl. Toxicol., 30, pp. 582-589 
504 |a (2004) Gastrulation: From Cells to Embryo, , Cold Spring Harbor Laboratory Press, New York, C.D. Stern (Ed.) 
504 |a Aris, A., Leblanc, S., Maternal and fetal exposure to pesticides associated to genetically modified foods in Eastern Townships of Quebec, Canada (2011) Reprod. Toxicol., 31, pp. 528-533 
504 |a Spiroux de Vendômois, J., Roullier, F., Cellier, D., Séralini, G.-E., A comparison of the effects of three GM corn varieties on mammalian health (2009) Int. J. Biol. Sci., 5, pp. 706-726 
504 |a vom Saal, F.S., Hughes, C., An extensive new literature concerning low-dose effects of bisphenol A shows the need for a new risk assessment (2005) Environ. Health Perspect., 113, pp. 926-933 
504 |a Vomsaal, F.S., Akingbemi, B.T., Belcher, S.M., Birnbaum, L.S., Crain, D.A., Eriksen, M., Chapel Hill bisphenol A expert panel consensus statement: integration of mechanisms, effects in animals and potential to impact human health at current levels of exposure (2007) Reprod. Toxicol., 24, pp. 131-138 
504 |a Antoniou, M., Habib, M.E.E.-D.M., Howard, C.V., Jennings, R.C., Leifert, C., Nodari, R.O., Roundup and birth defects. Is the public being kept in the dark? (2011) Earth Open Source Org, , http://www.earthopensource.org/index.php/reports/17-roundup-and-birth-defects-is-the-public-being-kept-in-the-dark 
520 3 |a In South America, the incorporation of genetically modified organisms (GMO) engineered to be resistant to pesticides changed the agricultural model into one dependent on the massive use of agrochemicals. Different pesticides are used in response to the demands of the global consuming market to control weeds, herbivorous arthropods, and crop diseases. Here, we review their effects on humans and animal models, in terms of genotoxicity, teratogenicity, and cell damage. We also stress the importance of biomarkers for medical surveillance of populations at risk and propose the use of biosensors as sensitive resources to detect undesirable effects of new molecules and environmental pollutants. The compatibility of glyphosate, the most intensively used herbicide associated to GMO crops, with an integrated pest management for soybean crops, is also discussed. © 2012 Elsevier B.V.  |l eng 
593 |a Laboratorio de Embriología Molecular, Instituto de Biología Celular y Neurociencias, Facultad de Medicina, Universidad de Buenos Aires, Paraguay 2155, 3 piso (1121), Ciudad Autónoma de Buenos Aires, Argentina 
593 |a GeMA -Genética y Mutagénesis Ambiental- Departamento de Ciencias Naturales, Facultad de Ciencias Exactas, Universidad Nacional de Río Cuarto, Ruta Nac. 36 - Km. 601. (X5804BYA), Río Cuarto, Córdoba, Argentina 
593 |a Ćtedra de Pediatría, Centro Materno Infantil (CMI), Facultad de Ciencias Médicas, Universidad Nacional de Asunción-Paraguay, Paraguay 
593 |a Ćtedra de Ecotoxicología, CONICET, Facultad de Bioquímica y Ciencias Biológicas, Universidad Nacional del Litoral, Paraje El Pozo s/n (3000), Santa Fe, Argentina 
593 |a Ćtedra de Toxicología, Farmacología y Bioquímica Legal, Facultad de Bioquímica y Ciencias Biológicas, Universidad Nacional del Litoral, Ciudad Universitaria, Pje. El Pozo (3000), Santa Fe, Argentina 
593 |a Laboratorio de Zoología Aplicada, Anexo Vertebrados (FHUC-UNL/MASPyMA), Aristóbulo del Valle 8700 (3000), Santa Fe, Argentina 
593 |a IEGEBA (CONICET-UBA), Buenos Aires, Argentina 
593 |a Centro de Estudios Parasitológicos y de Vectores (CEPAVE) (CCT La Plata CONICET - UNLP), Calle 2 N 584 (1900), La Plata, Argentina 
690 1 0 |a BIOMARKERS 
690 1 0 |a BIOSENSORS 
690 1 0 |a CYPERMETHRIN 
690 1 0 |a ENDOSULFAN 
690 1 0 |a GENETICALLY MODIFIED ORGANISMS 
690 1 0 |a GENOTOXICITY 
690 1 0 |a GLYPHOSATE 
690 1 0 |a GLYPHOSATE-BASED HERBICIDES 
690 1 0 |a PESTICIDES 
690 1 0 |a PRECAUTIONARY PRINCIPLE 
690 1 0 |a TERATOGENECITY 
690 1 0 |a ACETYLCHOLINESTERASE 
690 1 0 |a AGRICULTURAL CHEMICAL 
690 1 0 |a CHOLINESTERASE 
690 1 0 |a CIPERMETHRIN 
690 1 0 |a ENDOSULFAN 
690 1 0 |a GLYPHOSATE 
690 1 0 |a MALONALDEHYDE 
690 1 0 |a PESTICIDE 
690 1 0 |a RETINOIC ACID 
690 1 0 |a AGRICULTURE 
690 1 0 |a AMPHIBIA 
690 1 0 |a ARTHROPOD DISEASE 
690 1 0 |a ARTICLE 
690 1 0 |a BIOENGINEERING 
690 1 0 |a BIOSENSOR 
690 1 0 |a CAIMAN 
690 1 0 |a CELL DAMAGE 
690 1 0 |a CONGENITAL MALFORMATION 
690 1 0 |a DISEASE MODEL 
690 1 0 |a DNA DAMAGE 
690 1 0 |a ECOTOXICOLOGY 
690 1 0 |a GENOTOXICITY 
690 1 0 |a HEALTH SURVEY 
690 1 0 |a HUMAN 
690 1 0 |a INTEGRATED PEST MANAGEMENT 
690 1 0 |a LIPID PEROXIDATION 
690 1 0 |a MODEL 
690 1 0 |a NONHUMAN 
690 1 0 |a PERIODIC MEDICAL EXAMINATION 
690 1 0 |a PLANT DISEASE 
690 1 0 |a PLANT DISEASE CONTROL 
690 1 0 |a POLLUTANT 
690 1 0 |a PRIORITY JOURNAL 
690 1 0 |a SOYBEAN 
690 1 0 |a TERATOGENESIS 
690 1 0 |a TERATOGENICITY 
690 1 0 |a TRANSGENIC ORGANISM 
690 1 0 |a WEED 
651 4 |a ARGENTINA 
651 4 |a PARAGUAY 
700 1 |a Aiassa, D. 
700 1 |a Benítez-Leite, S. 
700 1 |a Lajmanovich, R. 
700 1 |a Mañas, F. 
700 1 |a Poletta, G. 
700 1 |a Sánchez, N. 
700 1 |a Simoniello, M.F. 
700 1 |a Carrasco, A.E. 
773 0 |d 2012  |g v. 6  |h pp. 41-75  |p Adv. Mol. Toxicol.  |x 18720854  |t Advances in Molecular Toxicology 
856 4 1 |u https://www.scopus.com/inward/record.uri?eid=2-s2.0-84865377038&doi=10.1016%2fB978-0-444-59389-4.00002-1&partnerID=40&md5=7f4d87bca73fb41a05dbcfdd18852b8d  |y Registro en Scopus 
856 4 0 |u https://doi.org/10.1016/B978-0-444-59389-4.00002-1  |y DOI 
856 4 0 |u https://hdl.handle.net/20.500.12110/paper_18720854_v6_n_p41_Lopez  |y Handle 
856 4 0 |u https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_18720854_v6_n_p41_Lopez  |y Registro en la Biblioteca Digital 
961 |a paper_18720854_v6_n_p41_Lopez  |b paper  |c PE 
962 |a info:eu-repo/semantics/article  |a info:ar-repo/semantics/artículo  |b info:eu-repo/semantics/publishedVersion 
999 |c 70349