13-cis-Retinal stimulates proliferation and induces intranuclear protein accumulation in the human mammary tumor cells MCF-7
The human mammary tumor cells MCF-7 show enhanced proliferation when treated with low dosis (10-8 - 10-7 M) of 13-cis Retinal (a vitamin A derivative). These results are independent of the growth medium used. We describe a novel effect of 13-cis Retinal: the increased synthesis and accumulation of n...
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| Formato: | Capítulo de libro |
| Lenguaje: | Inglés |
| Publicado: |
1987
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| Acceso en línea: | Registro en Scopus DOI Handle Registro en la Biblioteca Digital |
| Aporte de: | Registro referencial: Solicitar el recurso aquí |
| LEADER | 05468caa a22008897a 4500 | ||
|---|---|---|---|
| 001 | PAPER-913 | ||
| 003 | AR-BaUEN | ||
| 005 | 20230518203015.0 | ||
| 008 | 190411s1987 xx ||||fo|||| 00| 0 eng|d | ||
| 024 | 7 | |2 scopus |a 2-s2.0-0023151004 | |
| 024 | 7 | |2 cas |a Neoplasm Proteins; Nucleoproteins; Retinaldehyde, 116-31-4; Retinoids | |
| 040 | |a Scopus |b spa |c AR-BaUEN |d AR-BaUEN | ||
| 030 | |a BBRCA | ||
| 100 | 1 | |a Resnicoff, M. | |
| 245 | 1 | 0 | |a 13-cis-Retinal stimulates proliferation and induces intranuclear protein accumulation in the human mammary tumor cells MCF-7 |
| 260 | |c 1987 | ||
| 270 | 1 | 0 | |m Medrano, E.E.; Instituto de Investigaciones Bioquimicas Fundacion Campomar, A. Machado 151, 1405 Buenos Aires, Argentina |
| 506 | |2 openaire |e Política editorial | ||
| 504 | |a Jetten, (1984) Federation Proc, 43, p. 143 | ||
| 504 | |a Gold, Metelsman, Moore, Clarckson, (1981) Blood, 58, p. 139 | ||
| 504 | |a Kerr, Lippman, Jenkins, Myers, (1982) Cancer Res, 42, pp. 2069-2073 | ||
| 504 | |a Clamon, Chabot, Valeriote, Davilla, Vogel, Gorowski, Birch, (1985) Cancer Res, 45, pp. 1875-1878 | ||
| 504 | |a Boning, Kakunaga, Emura, Mohr, (1986) Exp. Cell. Res, 163, pp. 255-260 | ||
| 504 | |a Hiragun, Sato, Mitsui, (1983) Exp. Cell. Res, 145, pp. 71-78 | ||
| 504 | |a Jetten, Gilmer, Barrett, (1985) Proceedings of AACR, 26, p. 60 | ||
| 504 | |a Lotan, (1979) Cancer Res, 39, pp. 1014-1019 | ||
| 504 | |a Lacroix, Lippman, Binding of Retinoids to Human Breast Cancer Cell Lines and their Effects on Cell Growth (1981) Journal of Clinical Investigation, 65, pp. 586-591 | ||
| 504 | |a Cassidy, Lippman, Lacroix, Peck, Ozols, (1981) Am. Soc. Clin. Oncol, 22, p. 424 | ||
| 504 | |a Medrano, E.E., Larcher, F., Resnicoff, M. and Cafferata, E.G.A. (1986). Submitted for publication; Lowry, Rosenbrough, Farr, Randall, (1951) J. Biol. Chem, 193, pp. 265-275 | ||
| 504 | |a Mori, Kurabe, Furukawa, Kubo, Hayashi, (1986) Biochem. Biophys. Res. Commun, 136, pp. 300-305 | ||
| 504 | |a Salomon, Zwiebel, Bano, Lsonczy, Fehnnel, Kidwell, (1984) Cancer Res, 44, pp. 4069-4077 | ||
| 504 | |a Keydar, Chen, Karby, Weiss, Delarea, Radu, Chaitcick, Brenner, (1979) Eur. J. Cancer, 15, pp. 659-670 | ||
| 504 | |a Hackett, Smith, Springer, Owens, Nelson-Rees, Riggs, Gardner, (1977) J. Natl. Cancer Inst, 58, pp. 1795-1806 | ||
| 504 | |a Kellermayer, Prestayko, Hazlewood, (1984) Exp. Cell. Res, 152, pp. 255-259 | ||
| 504 | |a Sporn, Roberts, (1983) Cancer Res, 43, pp. 3034-3040 | ||
| 504 | |a Resnicoff, M. and Medrano, E.E. (1986). Manuscript in preparation | ||
| 520 | 3 | |a The human mammary tumor cells MCF-7 show enhanced proliferation when treated with low dosis (10-8 - 10-7 M) of 13-cis Retinal (a vitamin A derivative). These results are independent of the growth medium used. We describe a novel effect of 13-cis Retinal: the increased synthesis and accumulation of nuclear proteins in cronically treated cells. The cytoplasmic proteins and proteins released to the culture medium are transiently and oppositly modified. Moreover, cronic treated cells have growth advantages over the untreated counterparts in a clonogenic soft agar assay. © 1987. |l eng | |
| 536 | |a Detalles de la financiación: Consejo Nacional de Investigaciones Científicas y Técnicas | ||
| 536 | |a Detalles de la financiación: the excellent technical assistance of E.G.A. Cafferatta. for this work was from the Consejo National de Investigaciones .y Tecnicas de Argentina at which E.E.M. is a career researcher. the recipient of a fellowship from M.C. de la Barca Foundation. | ||
| 593 | |a Instituto de Investigaciones Bioquimicas Fundacion Campomar, A. Machado 151, 1405 Buenos Aires, Argentina | ||
| 593 | |a Facultad de Ciencias Exactas y Naturales (UBA), A. Machado 151, 1405 Buenos Aires, Argentina | ||
| 690 | 1 | 0 | |a GROWTH FACTOR |
| 690 | 1 | 0 | |a 13 CIS RETINAL |
| 690 | 1 | 0 | |a BREAST |
| 690 | 1 | 0 | |a BREAST TUMOR |
| 690 | 1 | 0 | |a CELL STRAIN MCF 7 |
| 690 | 1 | 0 | |a DOSE RESPONSE |
| 690 | 1 | 0 | |a DRUG MECHANISM |
| 690 | 1 | 0 | |a DRUG RESPONSE |
| 690 | 1 | 0 | |a GROWTH STIMULATION |
| 690 | 1 | 0 | |a HUMAN |
| 690 | 1 | 0 | |a HUMAN CELL |
| 690 | 1 | 0 | |a PHARMACOKINETICS |
| 690 | 1 | 0 | |a PRIORITY JOURNAL |
| 690 | 1 | 0 | |a PROTEIN SYNTHESIS |
| 690 | 1 | 0 | |a BREAST NEOPLASMS |
| 690 | 1 | 0 | |a CELL DIVISION |
| 690 | 1 | 0 | |a CELL LINE |
| 690 | 1 | 0 | |a CELL NUCLEUS |
| 690 | 1 | 0 | |a FEMALE |
| 690 | 1 | 0 | |a HUMAN |
| 690 | 1 | 0 | |a KINETICS |
| 690 | 1 | 0 | |a NEOPLASM PROTEINS |
| 690 | 1 | 0 | |a NUCLEOPROTEINS |
| 690 | 1 | 0 | |a RETINALDEHYDE |
| 690 | 1 | 0 | |a RETINOIDS |
| 690 | 1 | 0 | |a SUPPORT, NON-U.S. GOV'T |
| 700 | 1 | |a Medrano, E.E. | |
| 773 | 0 | |d 1987 |g v. 143 |h pp. 309-315 |k n. 1 |p Biochem. Biophys. Res. Commun. |x 0006291X |w (AR-BaUEN)CENRE-905 |t Biochemical and Biophysical Research Communications | |
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| 856 | 4 | 0 | |u https://doi.org/10.1016/0006-291X(87)90666-8 |y DOI |
| 856 | 4 | 0 | |u https://hdl.handle.net/20.500.12110/paper_0006291X_v143_n1_p309_Resnicoff |y Handle |
| 856 | 4 | 0 | |u https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0006291X_v143_n1_p309_Resnicoff |y Registro en la Biblioteca Digital |
| 961 | |a paper_0006291X_v143_n1_p309_Resnicoff |b paper |c PE | ||
| 962 | |a info:eu-repo/semantics/article |a info:ar-repo/semantics/artículo |b info:eu-repo/semantics/publishedVersion | ||
| 963 | |a VARI | ||
| 999 | |c 61866 | ||