Lipase-catalysed preparation of acyl derivatives of the germacranolide cnicin
Several acyl derivatives of cnicin were obtained through lipase-catalysed acylation and alcoholysis reactions. In most reactions lipases showed a regioselective behaviour affording only one product. Longer chain acyl derivatives were prepared at lower temperature than the used in lipase-catalysed re...
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2009
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| Acceso en línea: | Registro en Scopus DOI Handle Registro en la Biblioteca Digital |
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| LEADER | 08068caa a22012617a 4500 | ||
|---|---|---|---|
| 001 | PAPER-8800 | ||
| 003 | AR-BaUEN | ||
| 005 | 20230518203838.0 | ||
| 008 | 190411s2009 xx ||||fo|||| 00| 0 eng|d | ||
| 024 | 7 | |2 scopus |a 2-s2.0-68949122671 | |
| 024 | 7 | |2 cas |a cnicin, 24394-09-0; triacylglycerol lipase, 9001-62-1 | |
| 040 | |a Scopus |b spa |c AR-BaUEN |d AR-BaUEN | ||
| 030 | |a JMCEF | ||
| 100 | 1 | |a Monsalve, L.N. | |
| 245 | 1 | 0 | |a Lipase-catalysed preparation of acyl derivatives of the germacranolide cnicin |
| 260 | |c 2009 | ||
| 270 | 1 | 0 | |m Baldessari, A.; Laboratorio de Biocatálisis, Departamento de Química Orgánica y UMYMFOR, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Pabellón 2, C1428EGA Buenos Aires, Argentina; email: alib@qo.fcen.uba.ar |
| 506 | |2 openaire |e Política editorial | ||
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| 520 | 3 | |a Several acyl derivatives of cnicin were obtained through lipase-catalysed acylation and alcoholysis reactions. In most reactions lipases showed a regioselective behaviour affording only one product. Longer chain acyl derivatives were prepared at lower temperature than the used in lipase-catalysed reactions, to preclude side products formation. The enzymatic approach let to prepare a family of novel acetyl and fatty acid derivatives of cnicin which are not obtainable following traditional organic synthetic procedures. © 2008 Elsevier B.V. All rights reserved. |l eng | |
| 536 | |a Detalles de la financiación: Agencia Nacional de Promoción Científica y Tecnológica, PICT 2005, 32735 | ||
| 536 | |a Detalles de la financiación: We thank UBA (project X089), ANPCyT (project PICT 2005, 32735) (Argentina) and Italian Government project PRIN for partial financial support. AB is a Research Member of CONICET. | ||
| 593 | |a Laboratorio de Biocatálisis, Departamento de Química Orgánica y UMYMFOR, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Pabellón 2, C1428EGA Buenos Aires, Argentina | ||
| 593 | |a Dipartimento di Chimica Organica, Università di Palermo, Viale delle Scienze, 90128 Palermo, Italy | ||
| 690 | 1 | 0 | |a ACYLATION |
| 690 | 1 | 0 | |a ALCOHOLYSIS |
| 690 | 1 | 0 | |a CNICIN |
| 690 | 1 | 0 | |a ENZYME CATALYSIS |
| 690 | 1 | 0 | |a SESQUITERPENOIDS |
| 690 | 1 | 0 | |a ACYL DERIVATIVES |
| 690 | 1 | 0 | |a ALCOHOLYSIS |
| 690 | 1 | 0 | |a ALCOHOLYSIS REACTIONS |
| 690 | 1 | 0 | |a CNICIN |
| 690 | 1 | 0 | |a ENZYME CATALYSIS |
| 690 | 1 | 0 | |a FATTY ACID DERIVATIVES |
| 690 | 1 | 0 | |a GERMACRANOLIDE |
| 690 | 1 | 0 | |a REGIO-SELECTIVE |
| 690 | 1 | 0 | |a SESQUITERPENOIDS |
| 690 | 1 | 0 | |a SIDE PRODUCTS |
| 690 | 1 | 0 | |a SYNTHETIC PROCEDURES |
| 690 | 1 | 0 | |a ACYLATION |
| 690 | 1 | 0 | |a ENZYMES |
| 690 | 1 | 0 | |a FATTY ACIDS |
| 690 | 1 | 0 | |a LIPASES |
| 690 | 1 | 0 | |a CATALYSIS |
| 690 | 1 | 0 | |a ACETIC ACID DERIVATIVE |
| 690 | 1 | 0 | |a CNICIN |
| 690 | 1 | 0 | |a FATTY ACID DERIVATIVE |
| 690 | 1 | 0 | |a GERMACRANOLIDE DERIVATIVE |
| 690 | 1 | 0 | |a SESQUITERPENE LACTONE |
| 690 | 1 | 0 | |a TRIACYLGLYCEROL LIPASE |
| 690 | 1 | 0 | |a UNCLASSIFIED DRUG |
| 690 | 1 | 0 | |a ACYLATION |
| 690 | 1 | 0 | |a ALCOHOLYSIS |
| 690 | 1 | 0 | |a ARTICLE |
| 690 | 1 | 0 | |a CATALYSIS |
| 690 | 1 | 0 | |a CHEMICAL REACTION KINETICS |
| 690 | 1 | 0 | |a CHEMICAL STRUCTURE |
| 690 | 1 | 0 | |a CONTROLLED STUDY |
| 690 | 1 | 0 | |a ENANTIOSELECTIVITY |
| 690 | 1 | 0 | |a ENZYME ACTIVITY |
| 690 | 1 | 0 | |a LOW TEMPERATURE |
| 690 | 1 | 0 | |a NONHUMAN |
| 690 | 1 | 0 | |a SYNTHESIS |
| 700 | 1 | |a Rosselli, S. | |
| 700 | 1 | |a Bruno, M. | |
| 700 | 1 | |a Baldessari, A. | |
| 773 | 0 | |d 2009 |g v. 57 |h pp. 40-47 |k n. 1-4 |p J. Mol. Catal. B Enzym. |x 13811177 |w (AR-BaUEN)CENRE-5687 |t Journal of Molecular Catalysis B: Enzymatic | |
| 856 | 4 | 1 | |u https://www.scopus.com/inward/record.uri?eid=2-s2.0-68949122671&doi=10.1016%2fj.molcatb.2008.06.019&partnerID=40&md5=dde08295715678423ce433c61463e8a4 |y Registro en Scopus |
| 856 | 4 | 0 | |u https://doi.org/10.1016/j.molcatb.2008.06.019 |y DOI |
| 856 | 4 | 0 | |u https://hdl.handle.net/20.500.12110/paper_13811177_v57_n1-4_p40_Monsalve |y Handle |
| 856 | 4 | 0 | |u https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_13811177_v57_n1-4_p40_Monsalve |y Registro en la Biblioteca Digital |
| 961 | |a paper_13811177_v57_n1-4_p40_Monsalve |b paper |c PE | ||
| 962 | |a info:eu-repo/semantics/article |a info:ar-repo/semantics/artículo |b info:eu-repo/semantics/publishedVersion | ||
| 999 | |c 69753 | ||