Chapter 7 Glycobiology of Trypanosoma cruzi
The glycobiology of Trypanosoma cruzi, the causative agent of Chagas' disease, has contributed significantly to the identification of target enzymes responsible for the construction of unique cell-surface molecules. The authors discuss the structure of glycoinositolphospholipids, both free and...
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| Formato: | Capítulo de libro |
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2009
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| Acceso en línea: | Registro en Scopus DOI Handle Registro en la Biblioteca Digital |
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| 100 | 1 | |a de Lederkremer, R.M. | |
| 245 | 1 | 0 | |a Chapter 7 Glycobiology of Trypanosoma cruzi |
| 260 | |c 2009 | ||
| 270 | 1 | 0 | |m de Lederkremer, R.M.; CHIDECAR, Departamento de Química Orgánica, Facultad de Ciencias Exactas y Naturales, Pabellon II, Ciudad Universitaria, 1428 Buenos Aires, Argentina |
| 506 | |2 openaire |e Política editorial | ||
| 504 | |a Brener, Z., Biology of Trypanosoma cruzi (1973) Ann. Rev. Microbiol., 27, pp. 347-382 | ||
| 504 | |a Moncayo, A., Chagas Disease: Current epidemiological trends after the interruption of vectorial and transfusional transmission in the southern cone countries (2003) Mem. Inst. Oswaldo Cruz, 98, pp. 577-591 | ||
| 504 | |a El-Sayed, N.M., The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease (2005) Science, 309, pp. 409-415 | ||
| 504 | |a Zingales, B., Souto, R.P., Mangia, R.H., Lkboa, C.V., Campbell, D.A., Coura, J.R., Jansen, A., Fernandes, O., Molecular epidemiology of American trypanosomiasis in Brazil based on dimorphisms of r&WA and mini-exon gene sequences (1998) Int. J. Parasitol., 28, pp. 105-112 | ||
| 504 | |a Briones, M.R.S., Souto, R.P., Stolf, B.S., Zingales, B., The evolution of two Trypanosoma cruzi subgroups inferred from rRNA genes can be correlated with the interchange of American mammalian faunas in the Cenozoic and has implications to pathogenicity and host specificity (1999) Mol. Biochem. Parasitol., 104, pp. 219-232 | ||
| 504 | |a Bértoli, M., Andó, M.H., De Ornelas Toledo, M.J., De Araújo, S.M., Gomes, M.L., Infectivity for mice of Trypanosoma cruzi I and II strains isolated from different hosts (2006) Parasitol Res., 99, pp. 7-13 | ||
| 504 | |a Toledo, M.J.d.O., de Lana, M., Carneiro, C.M., Bahia, M.T., Machado-Coelho, G.L.L., Veloso, V.M., Barnabé, C., Tafuri, W.L., Impact of Trypanosoma cruzi clonal evolution on its biological properties in mice (2002) Exp. Parasitol., 100, pp. 161-172 | ||
| 504 | |a Fernandes, A.B., Mortara, R.A., Invasion of MDCK epithelial cells with altered expression of Rho GTPases by Trypanosoma cruzi amastigotes and metacyclic trypomastigotes of strains from the two major phylogenetic lineages (2004) Microbes Infect., 6, pp. 460-467 | ||
| 504 | |a De Souza, W., Basic cell biology of Trypanosoma cruzi (2002) Curr. Pharm. Des., 8, pp. 269-285 | ||
| 504 | |a de Lederkremer, R.M., Bertello, L.E., Glycoinositolphospholipids free and as anchors of proteins, in Trypanosoma cruzi (2001) Curr. Pharm. Des., 7, pp. 1165-1179 | ||
| 504 | |a Previato, J.O., Wait, R., Jones, C., Todeschini, A.R., Heise, N., Previato, L.M., Glycoinositolphospholipid from Trypanosoma cruzi: structure, biosynthesis and immunobiology (2004) Adv. Parasitol, 56, pp. 1-41 | ||
| 504 | |a de Lederkremer, R.M., Lima, C., Ramirez, M.I., Ferguson, M.A.J., Homans, S.W., Thomas-Oates, J., Complete structure of the glycan of lipopeptidophosphoglycan from Trypanosoma cruzi epimastigotes (1991) J. Biol. Chem., 266, pp. 23670-23675 | ||
| 504 | |a MacRae, J.L., Ferguson, M.A.J., A robust and selective method for the quantification of glycosylphosphatidylinositols in biological samples (2005) Glycobiology, 15, pp. 131-138 | ||
| 504 | |a de Lederkremer, R.M., Alves, M.J.M., Fonseca, G.C., Colli, W., A lipopeptidophosphoglycan from Trypanosoma cruzi (epimastigota). Isolation, purification and carbohydrate composition (1976) Biochim. Biophys. Acta., 444, pp. 85-96 | ||
| 504 | |a de Lederkremer, R.M., Casal, O.L., Tanaka, C.T., Colli, W., Ceramide and inositol content of the lipopeptidophosphoglycan from Trypanosoma cruzi (1978) Biochem. Biophys. Res. Commun., 85, pp. 1268-1274 | ||
| 504 | |a de Lederkremer, R.M., Casal, O.L., Alves, M.J.M., Colli, W., Trypanosoma cruzi: Aminoacid and phosphorus linkages in the lipopeptidophosphoglycan (1985) Biochem. Internat., 10, pp. 89-96 | ||
| 504 | |a de Lederkremer, R.M., Lima, C., Ramirez, M.I., Casal, O.L., Structural features of the lipopeptidophosphoglycan (LPPG) from Trypanosoma cruzi common with the glycophosphatidylinositol anchors (1990) Eur. J. Biochem., 192, pp. 337-345 | ||
| 504 | |a de Lederkremer, R.M., Lima, C., Vila, M.C., Ceramide 1-phosphate is released from a glycoinositol-phosphoceramide of Trypanosoma cruzi by rat blood plasma (1996) Mol. Biochem. Parasitol., 79, pp. 219-223 | ||
| 504 | |a Previato, J.O., Gorin, P.A., Mazurek, M., Xavier, M.T., Fournet, B., Wieruszesk, J.M., Mendonça-Previato, L., Primary structure of the oligosaccharide chain of lipopeptidophosphoglycan of epimastigote forms of Trypanosoma cruzi (1990) J. Biol. Chem., 265, pp. 2518-2526 | ||
| 504 | |a Ferguson, M.A.J., The structure, biosynthesis and functions of glycosylphosphatidylinositol anchors, and the contributions of trypanosome research (1999) J. Cell Sci., 112, pp. 2799-2809 | ||
| 504 | |a Carreira, J.C., Jones, C., Wait, R., Previato, J.O., Mendonça-Previato, L., Structural variation in the glycoinositolphospholipids of different strains of Trypanosoma cruzi (1996) Glycoconj. J., 13, pp. 955-966 | ||
| 504 | |a de Lederkremer, R.M., Lima, C., Ramirez, M.I., Gonçalvez, M.F., Colli, W., Hexadecylpalmitoylglycerol or ceramide is linked to similar glycophosphoinositol anchor-like structures in Trypanosoma cruzi (1993) Eur. J. Biochem., 218, pp. 929-936 | ||
| 504 | |a MacRae, J.I., Acosta-Serrano, A., Morrice, N.A., Mehlert, A., Ferguson, M.A.J., Structural Characterization of NETNES, a Novel Glycoconjugate in Trypanosoma cruzi Epimastigotes (2005) J. Biol. Chem., 280, pp. 12201-12211 | ||
| 504 | |a Golgher, D.B., Colli, W., Souto-Padron, T., Zingales, B., Galactofuranose-containing glycoconjugates of epimastigote and trypomastigote forms of Trypanosoma cruzi (1993) Mol. Biochem. Parasitol., 60, pp. 249-264 | ||
| 504 | |a Pereira-Chioccola, V.L., Acosta-Serrano, A., Correira de Almeida, I., Ferguson, M.A.J., Souto-Padron, T., Rodrigues, M.M., Travassos, L.R., Schenkman, S., Mucin-like molecules form a negatively charged coat that protects Trypanosoma cruzi trypomastigotes from killing by human anti-alpha-galactosyl antibodies (2000) J. Cell Sci., 113, pp. 1299-1307 | ||
| 504 | |a Ferguson, M.A.J., Homans, S.W., Dwek, R.A., Rademacher, T.W., Glycosyl-phosphatidylinositol moiety that anchors Trypanosoma brucei variant surface glycoprotein to the membrane (1988) Science, 239, pp. 753-759 | ||
| 504 | |a Roberts, W.L., Kim, B.H., Rosenberry, T.L., Differences in the glycolipid membrane anchors of bovine and human erythrocyte acetylcholinesterases (1987) Proc. Natl. Acad. Sci. USA, 84, pp. 7817-7821 | ||
| 504 | |a Armesto, J., Hannappel, E., Leopold, K., Fischer, W., Bublitz, R., Langer, L., Cumme, G.A., Horn, A., Microheterogeneity of the hydrophobic and hydrophilic part of the glycosylphosphatidylinositol anchor of alkaline phosphatase from calf intestine (1996) Eur. J. Biochem., 238, pp. 259-269 | ||
| 504 | |a Reggiori, F., Conzelmann, A., Biosynthesis of inositol phosphoceramides and remodeling of glycosylphosphatidylinositol anchors in Saccharomyces cerevisiae are mediated by different enzymes (1998) J. Biol. Chem., 273, pp. 30550-30559. , and references therein | ||
| 504 | |a Pollevick, G.D., Di Noia, J.M., Salto, M.L., Lima, C., Leguizamon, M.S., de Lederkremer, R.M., Frasch, A.C.C., Trypanosoma cruzi surface mucins with exposed variant epitopes (2000) J. Biol. Chem., 275, pp. 27671-27680 | ||
| 504 | |a Previato, J.O., Jones, C., Gonçalves, L.P.B., Wait, R., Travassos, L.R., Parodi, A.J., Mendonça-Previato, L., Structural characterization of the major glycosylphosphatidylinositol membrane-anchored glycoprotein from epimastigote forms of Trypanosoma cruzi Y-strain (1995) J. Biol. Chem., 270, pp. 7241-7250 | ||
| 504 | |a Acosta-Serrano, A., Schenkman, S., Yoshida, N., Mehlert, A., Richardson, J., Ferguson, M.A.J., The lipid structure of the glycosylphosphatidylinositol-anchored mucin-like sialic acid acceptors of Trypanosoma cruzi changes during parasite differentiation from epimastigotes to infective metacyclic trypomastigote froms (1995) J. Biol. Chem., 270, pp. 27244-27253 | ||
| 504 | |a Almeida, I.C., Camargo, M.M., Procopio, D.O., Silva, L.S., Mehlert, A., Travassos, L.R., Gazzinelli, R.T., Ferguson, M.A.J., Highly purified glycosylphosphatidylinositols from Trypanosoma cruzi are potent proinflammatory agents (2000) EMBO J., 19, pp. 1476-1485 | ||
| 504 | |a Camargo, M.M., Almeida, I.C., Pereira, M.E.S., Ferguson, M.A.J., Souto-Padrón, T., Rodrigues, M.M., Travassos, L.R., Schenkman, S., Glycoconjugates isolated from Trypanosoma cruzi but not from Leishmania species membranes trigger nitric oxide synthesis as well as microbicidal activity in IFN-gamma-primed macrophages (1997) J. Immunol., 158, pp. 5890-5901 | ||
| 504 | |a Agusti, R., Couto, A.S., Campetella, O.E., Frasch, A.C.C., De Lederkremer, R.M., The trans-sialidase of Trypanosoma cruzi is anchored by two different lipids (1997) Glycobiology., 7, pp. 731-735 | ||
| 504 | |a Agusti, R., Couto, A.S., Campetella, O., Frasch, A.C.C., de Lederkremer, R.M., Structure of the glycosylphosphatidylinositol-anchor of the trans-sialidase from Trypanosoma cruzi metacyclic trypomastigote forms (1998) Mol. Biochem. Parasitol., 97, pp. 123-131 | ||
| 504 | |a Alves, M.J.M., Colli, W., Role of the gp85/trans-sialidase superfamily of glycoproteins in the interaction of Trypanosoma cruzi with host structures (2008) Molecular Mechanisms of Parasite Invasion, 47, pp. 58-96. , Burleigh B.A., and Soldati-Favre D. (Eds) | ||
| 504 | |a Katzin, A.M., Colli, W., Lectin receptors in Trypanosoma cruzi. An N-acetyl-D-glucosamine-containing surface glycoprotein specific for the trypomastigote stage (1983) Biochim. Biophys. Acta., 727, pp. 403-411 | ||
| 504 | |a Couto, A.S., de Lederkremer, R.M., Colli, W., Alves, M.J.M., The glycosylphosphatidylinositol anchor of the trypomastigote specific Tc 85 glycoprotein from Trypanosoma cruzi. Metabolic labeling and structural studies (1993) Eur. J. Biochem., 217, pp. 597-602 | ||
| 504 | |a Abuin, G., Couto, A.S., Lederkremer, R.M., Casal, O.L., Galli, C., Colli, W., Alves, M.J.M., Trypanosoma cruzi: the Tc-85 surface glycoprotein shed by trypomastigotes bears a modified glycosylphosphatidylinositol anchor (1996) Exp. Parasitol., 72, pp. 290-297 | ||
| 504 | |a Guther, M.L., de Almeida, M.L., Yoshida, N., Ferguson, M.A.J., Structural studies on the glycosylphosphatidylinositol membrane anchor of Trypanosoma cruzi 1G7-antigen. The structure of the glycan core (1992) J. Biol. Chem., 267, pp. 6820-6828 | ||
| 504 | |a Heise, N., Cardoso de Almeida, M.L., Ferguson, M.A.J., Characterization of the lipid moiety of the glycosylphosphatidylinositol anchor of Trypanosoma cruzi 1G7-antigen (1995) Mol. Biochem. Parasitol., 70, pp. 71-84 | ||
| 504 | |a Bertello, L.E., Andrews, N.W., Lederkremer, R.M., Developmentally regulated expression of ceramide in Trypanosoma cruzi (1996) Mol. Biochem. Parasitol., 79, pp. 143-151 | ||
| 504 | |a Nogueira, N.F., Gonzalez, M.S., Gomes, J.E., de Souza, W., Garcia, E.S., Azambuja, P., Nohara, L.L., Colli, W., Trypanosoma cruzi: involvement of glycoinositolphospholipids in the attachment to the luminal midgut surface of Rhodnius prolixus (2007) Exp. Parasitol., 116, pp. 120-128 | ||
| 504 | |a Garg, N., Tarleton, R.L., Mensa-Wilmot, K., Proteins with glycosylphosphatidylinositol (GPI) signal sequences have divergent fates during a GPI deficiency. GPIs are essential for nuclear division in Trypanosoma cruzi (1997) J. Biol. Chem., 272, pp. 12482-12491 | ||
| 504 | |a Garg, N., Postan, M., Mensa-Wilmot, K., Tarleton, R.L., Glycosylphosphatidylinositols are required for the development of Trypanosoma cruzi amastigotes (1997) Infect. Immun., 65, pp. 4055-4060 | ||
| 504 | |a Mortara, R.A., Minelli, L.M., Vandekerckhove, F., Nussenzwieg, V., Ramalho-Pinto, F.J., Phosphatidylinositol-specific phospholipase C (PI-PLC) cleavage of GPI-anchored surface molecules of Trypanosoma cruzi triggers in vitro morphological reorganization of trypomastigotes (2002) J. Eukaryot. Microbiol., 48, pp. 27-37 | ||
| 504 | |a Salto, M.L., Bertello, L.E., Vieira, M., Docampo, R., Moreno, S.N., de Lederkremer, R.M., Formation and remodeling of inositolphosphoceramide during differentiation of Trypanosoma cruzi from trypomastigote to amastigote (2003) Eukaryot. Cell., 2, pp. 756-768 | ||
| 504 | |a Gomes, N.A., Previato, J.O., Zingales, B., Mendonça-Previato, L., DosReis, G.A., Down-regulation of T lymphocyte activation in vitro and in vivo induced by glycoinositolphospholipids from Trypanosoma cruzi. Assignment of the T cell-suppressive determinant to the ceramide domain (1996) J. Immunol., 156, pp. 628-635 | ||
| 504 | |a Bento, C.A., Melo, M.B., Previato, J.O., Mendonça-Previato, L., Peçanha, L.M., Glycoinositolphospholipids purified from Trypanosoma cruzi stimulate Ig production in vitro (1996) J. Immunol., 157, pp. 4996-5001 | ||
| 504 | |a Freire de Lima, C.G., Nunes, M.P., Corte-Real, S., Soares, M.P., Previato, J.O., Mendonça-Previato, L., DosReis, G.A., Proapoptotic activity of a Trypanosoma cruzi ceramide-containing glycolipid turned on in host macrophages by IFN-gamma (1998) J. Immunol., 161, pp. 4909-4916 | ||
| 504 | |a DosReis, G.A., Peçanha, L.M., Bellio, M., Previato, J.O., Mendonça-Previato, L., Glycoinositol phospholipids from Trypanosoma cruzi transmit signals to the cells of the host immune system through both ceramide and glycan chains (2002) Microbes Infect., 4, pp. 1007-1013 | ||
| 504 | |a Almeida, I.C., Gazzinelli, R.T., Proinflammatory activity of glycosylphosphatidylinositol anchors derived from Trypanosoma cruzi: structural and functional analyses (2001) J. Leukoc. Biol., 70, pp. 467-477 | ||
| 504 | |a Masterson, W.J., Doering, T.L., Hart, G.W., Englund, P.T., A novel pathway for glycan assembly: biosynthesis of the glycosyl-phosphatidylinositol anchor of the trypanosome variant surface glycoprotein (1989) Cell., 56, pp. 793-800 | ||
| 504 | |a Ferguson, M.A.J., Brimacombe, J.S., Brown, J.R., Crossman, A., Dix, A., Field, R.A., Güther, M.L., Smith, T.K., The GPI biosynthetic pathway as a therapeutic target for African sleeping sickness (1999) Biochim. Biophys. Acta., 1455, pp. 327-340 | ||
| 504 | |a Morita, Y.S., Englund, P.T., Fatty acid remodeling of glycosyl phosphatidylinositol anchors in Trypanosoma brucei: incorporation of fatty acids other than myristate (2001) Mol. Biochem. Parasitol., 115, pp. 157-164 | ||
| 504 | |a Guther, M.L., Ferguson, M.A.J., The role of inositol acylation and inositol deacylation in GPI biosynthesis in Trypanosoma brucei (1995) EMBO J., 14, pp. 3080-3093 | ||
| 504 | |a Roberts, W.L., Santikarn, S., Reinhold, V.N., Rosenberry, T.L., Structural characterization of the glycoinositol phospholipid membrane anchor of human erythrocyte acetylcholinesterase by fast atom bombardment mass spectrometry (1988) J. Biol. Chem., 263, pp. 18776-18784 | ||
| 504 | |a Guther, M.L., Leal, S., Morrice, N.A., Cross, G.A., Ferguson, M.A.J., Purification, cloning and characterization of a GPI inositol deacylase from Trypanosoma brucei (2001) EMBO J., 20, pp. 4923-4934 | ||
| 504 | |a Orlean, P., Menon, A.K., Thematic review series: lipid posttranslational modifications. GPI anchoring of protein in yeast and mammalian cells, or: how we learned to stop worrying and love glycophospholipids (2007) J. Lipid Res., 48, pp. 993-1011 | ||
| 504 | |a Sipos, G., Puoti, A., Conzelmann, A., Glycosylphosphatidylinositol membrane anchors in Saccharomyces cerevisiae: absence of ceramides from complete precursor glycolipids (1994) EMBO J., 13, pp. 2789-2796 | ||
| 504 | |a Sipos, G., Reggiori, F., Vionnet, C., Conzelmann, A., Alternative lipid remodelling pathways for glycosylphosphatidylinositol membrane anchors in Saccharomyces cerevisiae (1997) EMBO J., 16, pp. 3494-3505 | ||
| 504 | |a Reggiori, F., Canivenc-Gansel, E., Conzelmann, A., Lipid remodeling leads to the introduction and exchange of defined ceramides on GPI proteins in the ER and Golgi of Saccharomyces cerevisiae (1997) EMBO J., 16, pp. 3506-3518 | ||
| 504 | |a Pittet, M., Conzelmann, A., Biosynthesis and function of GPI proteins in the yeast Saccharomyces cerevisiae (2007) Biochim. Biophys Acta., 1771, pp. 405-420 | ||
| 504 | |a Bertello, L.E., Alves, M.J.M., Colli, W., de Lederkremer, R.M., Inositolphosphoceramide is not a substrate for the first steps in the biosynthesis of glycoinositolphospholipids in Trypanosoma cruzi (2004) Mol. Biochem. Parasitol., 133, pp. 71-80 | ||
| 504 | |a Heise, N., Raper, J., Buxbaum, L.U., Peranovich, T.M., de Almeida, M.L., Identification of complete precursors for the glycosylphosphatidylinositol protein anchors of Trypanosoma cruzi (1996) J. Biol. Chem., 271, pp. 16877-16887 | ||
| 504 | |a Bertello, L.E., Goncalvez, M.F., Colli, W., de Lederkremer, R.M., Structural analysis of inositol phospholipids from Trypanosoma cruzi epimastigote forms (1995) Biochem. J., 310, pp. 255-261 | ||
| 504 | |a Bertello, L.E., Alves, M.J.M., Colli, W., de Lederkremer, R.M., Evidence for phospholipases from Trypanosoma cruzi active on phosphatidylinositol and inositolphosphoceramide (2000) Biochem. J., 345, pp. 77-84 | ||
| 504 | |a Zhu, Y., Vionnet, C., Conzelmann, A., Ethanolaminephosphate side chain added to glycosylphosphatidylinositol (GPI) anchor by mcd4p is required for ceramide remodeling and forward transport of GPI proteins from endoplasmic reticulum to Golgi (2006) J. Biol. Chem., 281, pp. 19830-19839 | ||
| 504 | |a Uhrig, M.L., Couto, A.S., Colli, W., de Lederkremer, R.M., Characterization of inositolphospholipids in Trypanosoma cruzi trypomastigote forms (1996) Biochim. Biophys. Acta., 1300, pp. 233-239 | ||
| 504 | |a Figueiredo, J.M., Dias, W.B., Mendonça-Previato, L., Previato, J.O., Heise, N., Characterization of the inositol phosphorylceramide synthase activity from Trypanosoma cruzi (2005) Biochem. J., 387, pp. 519-529 | ||
| 504 | |a Undenfriend, S., Kodukula, K., How glycosylphosphatidylinositol-anchored membrane proteins are made (1995) Annu. Rev. Biochem., 64, pp. 563-591 | ||
| 504 | |a Eisenhaber, B., Bork, P., Eisenhaber, F., Sequence properties of GPI-anchored proteins near the omega-site: constraints for the polypeptide binding site of the putative transamidase (1998) Protein Eng., 11, pp. 1155-1161 | ||
| 504 | |a Nagamune, K., Ohishi, K., Ashida, H., Hong, Y., Hino, J., Kangawa, K., Inoue, N., Kinoshita, T., GPI transamidase of Trypanosoma brucei has two previously uncharacterized (trypanosomatid transamidase 1 and 2) and three common subunits (2003) Proc. Natl. Acad. Sci. USA, 100, pp. 10682-10687 | ||
| 504 | |a Hong, Y., Nagamune, K., Ohishi, K., Morita, Y.S., Ashida, H., Maeda, Y., Kinoshita, T., TbGPI16 is an essential component of GPI transamidase in Trypanosoma brucei (2006) FEBS Lett, 580, pp. 603-606 | ||
| 504 | |a Hederos, M., Konradsson, P., Synthesis of the Trypanosoma cruzi LPPG heptasaccharyl myo-inositol (2006) J. Am. Chem. Soc., 128, pp. 3414-3419 | ||
| 504 | |a Hederos, M., Konradsson, P., Synthesis of the core tetrasaccharide of Trypanosoma cruzi glycoinositolphospholipids: Manp(α1→6)-Manp(α1→4)-6-(2-aminoethylphosphonic acid)-GlcNp(α1→6)-myo-Ins-1-PO4 (2005) J. Org. Chem., 70, pp. 196-207 | ||
| 504 | |a Randell, K.D., Johnston, B.D., Browin, P.N., Pinto, B.M., Synthesis of galactofuranosyl-containing oligosaccharides corresponding to the glycosylinositolphospholipid of Trypanosoma cruzi (2000) Carbohydr. Res., 325, pp. 253-264 | ||
| 504 | |a Yashunsky, D.V., Borodkin, V.S., Ferguson, M.A.J., Nikolaev, A.V., The chemical synthesis of bioactive glycosylphosphatidylinositols from Trypanosoma cruzi containing an unsaturated fatty acid in the lipid (2006) Angew. Chem. Int. Ed. Engl., 45, pp. 468-474 | ||
| 504 | |a Schenkman, S., Ferguson, M.A.J., Heise, N., de Almeida, M.L., Mortara, R.A., Yoshida, N., Mucin-like glycoproteins linked to the membrane by glycosylphosphatidylinositol anchor are the major acceptors of sialic acid in a reaction catalyzed by trans-sialidase in metacyclic forms of Trypanosoma cruzi (1993) Mol. Biochem. Parasitol., 59, pp. 293-303 | ||
| 504 | |a Acosta-Serrano, A., Almeida, I.C., Freitas-Junior, L.H.G., Yoshida, N., Schenkman, S., The mucin-like glycoprotein super-family of Trypanosoma cruzi: structure and biological roles (2001) Mol. Biochem. Parasitol., 114, pp. 143-150 | ||
| 504 | |a Alves, M.J.M., Colli, W., Glycoproteins from Trypanosoma cruzi: partial purification by gel chromatography (1975) FEBS Lett., 52, pp. 188-190 | ||
| 504 | |a Zingales, B., Martin, N.F., de Lederkremer, R.M., Colli, W., Endogenous and surface labeling of glycoconjugates from the three differentiation stages of Trypanosoma cruzi (1982) FEBS Lett., 142, pp. 238-242 | ||
| 504 | |a Buscaglia, C.A., Campo, V.A., Frasch, A.C.C., Di Noia, J.M., Trypanosoma cruzi surface mucins: host-dependent coat diversity (2006) Nat. Rev. Microbiol, 4, pp. 229-236 | ||
| 504 | |a Frasch, A.C.C., Functional diversity in the trans-sialidase and mucin families in Trypanosoma cruzi (2000) Parasitol. Today, 16, pp. 282-286 | ||
| 504 | |a Di Noia, J.M., D'Orso, I., Sanchez, D.O., Frasch, A.C.C., AU-rich elements in the 3′-untranslated region of a new mucin-type family of Trypanosoma cruzi confers mRNA instability and modulates translation efficiency (2000) J. Biol. Chem., 275, pp. 10218-10227 | ||
| 504 | |a Di Noia, J.M., Sanchez, D.O., Frasch, A.C.C., The protozoan Trypanosoma cruzi has a family of genes resembling the mucin genes of mammalian cells (1995) J. Biol. Chem., 270, pp. 24146-24149 | ||
| 504 | |a Di Noia, J.M., D'Orso, I., Aslund, L., Sanchez, D.O., Frasch, A.C.C., The Trypanosoma cruzi mucin family is transcribed from hundreds of genes having hypervariable regions (1998) J. Biol. Chem., 273, pp. 10843-10850 | ||
| 504 | |a Freitas-Junior, L.H.G., Briones, M.R.S., Schenkman, S., Two distinct groups of mucin-like genes are differentially expressed in the developmental stages of Trypanosoma cruzi (1998) Mol. Biochem. Parasitol., 93, pp. 101-114 | ||
| 504 | |a Buscaglia, C.A., Campo, V.A., Di Noia, J.M., Torrecillas, A.C.T., De Marchi, C.R., Ferguson, M.A.J., Frasch, A.C.C., Almeida, I.C., The surface coat of the mammal-dwelling infective trypomastigote stage of Trypanosoma cruzi is formed by highly diverse immunogenic mucins (2004) J. Biol. Chem., 279, pp. 15860-15869 | ||
| 504 | |a Schenkman, S., Jiang, M., Hart, G.W., Nussenzweig, V., A novel cell surface trans-sialidase of Trypanosoma cruzi generates a stage-specific epitope required for invasion of mammalian cells (1991) Cell, 65, pp. 1117-1125 | ||
| 504 | |a Di Noia, J.M., Buscaglia, C.A., De Marchi, C.R., Almeida, I.C., Frasch, A.C.C., A Trypanosoma cruzi small surface molecule provides the first immunological evidence that Chagas' Disease is due to a single parasite lineage (2002) J. Exp. Med., 195, pp. 401-413 | ||
| 504 | |a Souto, R.P., Fernandes, O., Macedo, A.M., Campbell, D.A., Zingales, B., DNA markers define two phylogenetic lineages of Trypanosoma cruzi (1996) Mol. Biochem. Parasitol., 83, pp. 141-152 | ||
| 504 | |a Zingales, B., Stolf, B.S., Souto, R.P., Fernandes, O., Briones, M.R.S., Epidemiology, biochemistry and evolution of Trypanosoma cruzi lineages based on ribosomal RNA sequences (1999) Mem. Inst. Oswaldo Cruz., 94 (SUPPL. 1), pp. 159-164 | ||
| 504 | |a Atwood III, J.A., The Trypanosoma cruzi proteome (2005) Science, 309, pp. 473-476 | ||
| 504 | |a Atwood III, J.A., Glycoproteomics of Trypanosoma cruzi trypomastigotes using subcellular fractionation, lectin affinity, and stable isotope labeling (2006) J. Proteome Res., 5, pp. 3376-3384 | ||
| 504 | |a Allen, C.L., Kelly, J.M., Trypanosoma cruzi: mucin pseudogenes organized in a tandem array (2001) Exp. Parasitol., 97, pp. 173-177 | ||
| 504 | |a Campo, V.A., Di Noia, J.M., Buscaglia, C.A., Aguero, F., Sanchez, D.O., Frasch, A.C.C., Differential accumulation of mutations localized in particular domains of the mucin genes expressed in the vertebrate host stage of Trypanosoma cruzi (2004) Mol. Biochem. Parasitol., 133, pp. 81-91 | ||
| 504 | |a Tetaud, E., Barret, M.P., Bringaud, F., Baltz, T., Kinetoplastid glucose transporters (1997) Biochem. J., 325, pp. 569-580 | ||
| 504 | |a Roper, J.R., Ferguson, M.A.J., Cloning and characterisation of the UDP-glucose 4′-epimerase of Trypanosoma cruzi (2003) Mol. Biochem. Parasitol., 132, pp. 47-53 | ||
| 504 | |a Beverley, S.M., Owens, K.L., Showalter, M., Griffith, C.L., Doering, T.L., Jones, V.C., McNeil, M.R., Eukaryotic UDP-galactopyranose mutase (GLF gene) in microbial and metazoal pathogens (2005) Eukaryot. Cell, 4, pp. 1147-1154 | ||
| 504 | |a Bakker, H., Kleczka, B., Gerardy-Schahn, R., Routier, F.H., Identification and partial characterization of two eukaryotic UDP-galactopyranose mutases (2005) Biol. Chem., 386, pp. 657-661 | ||
| 504 | |a MacRae, J.I., Obado, S.O., Turnock, D.C., Roper, J.R., Kierans, M., Kelly, J.M., Ferguson, M.A.J., The suppression of galactose metabolism in Trypanosoma cruzi epimastigotes causes changes in cell surface molecular architecture and cell morphology (2006) Mol. Biochem. Parasitol., 147, pp. 126-136 | ||
| 504 | |a Salto, M.L., Gallo-Rodriguez, C., Lima, C., de Lederkremer, R.M., Separation of Galfβ1-XGlcNAc and Galpβ-XGlcNAc (X = 3, 4, and 6) as the alditols by high-pH anion-exchange chromatography and thin-layer chromatography: characterization of mucins from Trypanosoma cruzi (2000) Anal. Biochem., 279, pp. 79-84 | ||
| 504 | |a Previato, J.O., Sola-Penna, M., Agrellos, O.A., Jones, C., Oekmann, T., Travassos, L.R., Mendonça-Previato, L., Biosynthesis of O-N-acetylglucosamine-linked glycans in Trypanosoma cruzi. Characterization of the novel uridine diphospho-N-acetylglucosamine:polypeptide N-acetylglucosaminyltransferase-catalyzing formation of N-acetylglucosamine α1-O-threonine (1998) J. Biol. Chem., 273, pp. 14982-14988 | ||
| 504 | |a de Lederkremer, R.M., Confalonieri, A.N., Different pattern of glycoproteins with unusual O-linked oligosaccharides in two strains of Trypanosoma cruzi epimastigotes (1994) Ciencia e cultura., 46, pp. 286-289 | ||
| 504 | |a Previato, J.O., Jones, C., Goncalves, L.B.P., Wait, R., Travassos, L.R., Mendonça-Previato, L., O-Glycosidically linked N-acetylglucosamine-bound oligosaccharides from glycoproteins of Trypanosoma cruzi (1994) Biochem. J., 301, pp. 151-159 | ||
| 504 | |a Agrellos, O.A., Jones, C., Todeschini, A.R., Previato, J.O., Mendonça-Previato, L., A novel sialylated and galactofuranose-containing O-linked glycan, Neu5Acα-3Galpβ-6(Galfβ-4)GlcNAc, is expressed on the sialoglycoprotein of Trypanosoma cruzi Dm28c (2003) Mol. Biochem. Parasitol., 126, pp. 93-96 | ||
| 504 | |a Jones, C., Todeschini, A.R., Agrellos, O.A., Previato, J.O., Mendonça-Previato, L., Heterogeneity in the biosynthesis of mucin O-glycans from Trypanosoma cruzi tulahuen strain with the expression of novel galactofuranosyl-containing oligosaccharides (2004) Biochemistry, 43, pp. 11889-11897 | ||
| 504 | |a Todeschini, A.R., da Silveira, E.X., Jones, C., Wait, R., Previato, J.O., Mendonça-Previato, L., Structure of O-glycosidically linked oligosaccharides from glycoproteins of Trypanosoma cruzi CL-Brener strain: evidence for the presence of O-linked sialyl-oligosaccharides (2001) Glycobiology, 11, pp. 47-55 | ||
| 504 | |a de Arruda, M.V., Colli, W., Zingales, B., Terminal β-d-galactofuranosyl epitopes recognized by antibodies that inhibit Trypanosoma cruzi internalization into mammalian cells (1989) Eur. J. Biochem., 182, pp. 413-421 | ||
| 504 | |a Gallo-Rodriguez, C., Varela, O., de Lederkremer, R.M., First Synthesis of β-d-Galf(1-4)GlcNAc, a Structural Unit Attached O-Glycosidically in Glycoproteins of Trypanosoma cruzi (1996) J. Org. Chem., 61, pp. 1886-1889 | ||
| 504 | |a Gallo-Rodriguez, C., Varela, O., de Lederkremer, R.M., One-pot synthesis of β-d-Galf(1-4)[β-d-Galp(1-6)]-d-GlcNAc, a 'core' trisaccharide linked O-glycosidically in glycoproteins of Trypanosoma cruzi (1998) Carbohydr. Res., 305, pp. 163-170 | ||
| 504 | |a Gallo-Rodriguez, C., Gandolfi, L., de Lederkremer, R.M., Synthesis of β-d-Galf-(1-3)-d-GlcNAc by the trichloroacetamidate method and of β-d-Galf-(1-6)-D-GlcNAc by SnCl4-promoted glycosylation (1999) Org. Lett., 1, pp. 245-247 | ||
| 504 | |a Gallo-Rodriguez, C., Gil-Libarona, M.A., Mendoza, V.M., de Lederkremer, R.M., Synthesis of β-d-Galp-(1-3)- β-d-Galp(1-6)-[ β-d-Galf(1-4)]-d-GlcNAc, a tetrasaccharide component of mucins of Trypanosoma cruzi (2002) Tetrahedron, 58, pp. 9373-9380 | ||
| 504 | |a Gandolfi-Donadio, L., Gallo-Rodriguez, C., de Lederkremer, R.M., Synthesis of α-d-Galp(1-3)- β-d-Galf(1-3)-d-Man, a terminal trisaccharide of Leishmania type-2 glycoinositolphospholipids (2002) J. Org. Chem., 67, pp. 4430-4435 | ||
| 504 | |a Mendoza, V.M., Gallo-Rodriguez, C., de Lederkremer, R.M., Syntheses of 2,3-di-O-(β-d-Galp)-d-Galp, a synthon for the mucin oligosaccharides of Trypanosoma cruzi (2003) Arkivoc, pp. 82-94 | ||
| 504 | |a Schmidt, R.R., Jung, K.H., Oligosaccharide synthesis with trichloroacetimidates (1997) Preparative Carbohydrate Chemistry, , Hanessian S. (Ed), Marcel Dekker, Inc, New York | ||
| 504 | |a Mendoza, V.M., Agusti, R., Gallo-Rodriguez, C., de Lederkremer, R.M., Synthesis of the O-linked pentasaccharide in glycoproteins of Trypanosoma cruzi and selective sialylation by recombinant trans-sialidase (2006) Carbohydr. Res., 341, pp. 1488-1497 | ||
| 504 | |a Campo, V.A., Carvalho, I., Allman, S., Davis, B.G., Field, R.A., Chemical and chemoenzymatic synthesis of glycosyl-amino acids and glycopeptides related to Trypanosoma cruzi mucins (2007) Org. Biomol. Chem., 5, pp. 2645-2657 | ||
| 504 | |a Agusti, R., Giorgi, M.E., Mendoza, V.M., Gallo-Rodriguez, C., de Lederkremer, R.M., Comparative rates of sialylation by recombinant trans-sialidase and inhibitor properties of synthetic oligosaccharides from Trypanosoma cruzi mucins-containing galactofuranose and galactopyranose (2007) Bioorg. Med. Chem., 15, pp. 2611-2617 | ||
| 504 | |a Almeida, I.C., Ferguson, M.A.J., Schenkman, S., Travassos, L.R., Lytic anti- α-galactosyl antibodies from patients with chronic Chagas' disease recognize novel O-linked oligosaccharides on mucin-like glycosylphosphatidylinositol-anchored glycoproteins of Trypanosoma cruzi (1994) Biochem J., 304, pp. 793-802 | ||
| 504 | |a Mortara, R.A., da Silva, S., Araguth, M.F., Blanco, S.A., Yoshida, N., Polymorphism of the 35- and 50-kilodalton surface glycoconjugates of Trypanosoma cruzi metacyclic trypomastigotes (1992) Infect. Immun., 60, pp. 4673-4678 | ||
| 504 | |a Yoshida, N., Mortara, R.A., Araguth, M.F., Gonzalez, J.C., Russo, M., Metacyclic neutralizing effect of monoclonal antibody 10D8 directed to the 35- and 50-kilodalton surface glycoconjugates of Trypanosoma cruzi (1989) Infect. Immun., 57, pp. 1663-1667 | ||
| 504 | |a de C Ruiz, R., Rigoni, V.L., Gonzalez, J., Yoshida, N., The 35/50 kDa surface antigen of Trypanosoma cruzi metacyclic trypomastigotes, an adhesion molecule involved in host cell invasion (1993) Parasite Immunol., 15, pp. 121-125 | ||
| 504 | |a Ruiz, R.C., Favoreto Jr., S., Dorta, M.L., Oshiro, M.E., Ferreira, A.T., Manque, P.M., Yoshida, N., Infectivity of Trypanosoma cruzi strains is associated with differential expression of surface glycoproteins with differential Ca2+ signalling activity (1998) Biochem. J., 330, pp. 505-511 | ||
| 504 | |a Moreno, S.N., Silva, J., Vercesi, A.E., Docampo, R., Cytosolic-free calcium elevation in Trypanosoma cruzi is required for cell invasion (1994) J. Exp. Med., 180, pp. 1535-1540 | ||
| 504 | |a Turner, C.W., Lima, M.F., Villalta, F., Trypanosoma cruzi uses a 45-KDa mucin for adhesion to mammalian cells (2002) Biochem. Biophys. Res. Commun., 290, pp. 29-34 | ||
| 504 | |a Chuenkova, M., Pereira, M.E.S., Trypanosoma cruzi trans-sialidase: enhancement of virulence in a murine model of Chagas' disease (1995) J. Exp. Med., 181, pp. 1693-1703 | ||
| 504 | |a Tomlinson, S., Raper, J., Natural human immunity to trypanosomes (1998) Parasitol. Today, 14, pp. 354-359 | ||
| 504 | |a Previato, J.O., Andrade, A.F., Pessolani, M.C., Mendonça-Previato, L., Incorporation of sialic acid into Trypanosoma cruzi macromolecules. A proposal for a new metabolic route (1985) Mol. Biochem. Parasitol., 16, pp. 85-96 | ||
| 504 | |a Zingales, B., Carniol, C., de Lederkremer, R.M., Colli, W., Direct sialic acid transfer from a protein donor to glycolipids of trypomastigote forms of Trypanosoma cruzi (1987) Mol. Biochem. Parasitol., 26, pp. 135-144 | ||
| 504 | |a Colli, W., Trans-sialidase: a unique enzyme activity discovered in the protozoan Trypanosoma cruzi (1993) FASEB J., 7, pp. 1257-1264 | ||
| 504 | |a Cross, G.A., Takle, G.B., The surface trans-sialidase family of Trypanosoma cruzi (1993) Annu. Rev. Microbiol., 47, pp. 385-411 | ||
| 504 | |a Schenkman, S., Eichinger, D., Pereira, M.E.S., Nussenzweig, V., Structural and functional properties of Trypanosoma trans-sialidase (1994) Annu. Rev. Microbiol., 48, pp. 499-523 | ||
| 504 | |a Vandekerckhove, F., Schenkman, S., Pontes de Carvalho, L., Tomlinson, S., Kiso, M., Yoshida, M., Hasegawa, A., Nussenzweig, V., Substrate specificity of the Trypanosoma cruzi trans-sialidase (1992) Glycobiology, 2, pp. 541-548 | ||
| 504 | |a Ferrero-Garcia, M.A., Trombetta, S.E., Sanchez, D.O., Reglero, A., Frasch, A.C.C., Parodi, A.J., The action of Trypanosoma cruzi trans-sialidase on glycolipids and glycoproteins (1993) Eur. J. Biochem., 213, pp. 765-771 | ||
| 504 | |a Agusti, R., Giorgi, M.E., de Lederkremer, R.M., The trans-sialidase from Trypanosoma cruzi efficiently transfers alpha-(2-->3)-linked N-glycolylneuraminic acid to terminal beta-galactosyl units (2007) Carbohydr. Res., 342, pp. 2465-2569 | ||
| 504 | |a Schroven, A., Meinke, S., Ziegelmuller, P., Thiem, J., Transsialidase from Trypanosoma cruzi for regio- and stereoselective synthesis of N-acyl-modified sialylated oligosaccharides and measurement of transfer rates (2007) Chem. Eur. J., 13, pp. 9012-9021 | ||
| 504 | |a Parodi, A.J., Pollevick, G.D., Mautner, M., Buschiazzo, A., Sanchez, D.O., Frasch, A.C.C., Identification of the gene(s) coding for the trans-sialidase of Trypanosoma cruzi (1992) EMBO J., 11, pp. 1705-1710 | ||
| 504 | |a Affranchino, J.L., Ibañez, C.F., Luquetti, A.O., Rassi, A., Reyes, M.B., Macina, R.A., Aslund, L., Frasch, A.C.C., Identification of a Trypanosoma cruzi antigen that is shed during the acute phase of Chagas' disease (1989) Mol. Biochem. Parasitol., 34, pp. 221-228 | ||
| 504 | |a Reyes, M.B., Lorca, M., Muñoz, P., Frasch, A.C.C., Fetal IgG specificities against Trypanosoma cruzi antigens in infected newborns (1990) Proc. Natl. Acad. Sci. USA, 87, pp. 2846-2850 | ||
| 504 | |a Cremona, M.L., Campetella, O., Sanchez, D.O., Frasch, A.C.C., Enzymically inactive members of the trans-sialidase family from Trypanosoma cruzi display beta-galactose binding activity (1999) Glycobiology, 9, pp. 581-587 | ||
| 504 | |a Buschiazzo, A., Tavares, G.A., Campetella, O., Spinelli, S., Cremona, M.L., Paris, G., Amaya, M.F., Alzari, P.M., Structural basis of sialyltransferase activity in trypanosomal sialidases (2000) EMBO J., 19, pp. 16-24 | ||
| 504 | |a Campetella, O.E., Uttaro, A.K., Parodi, A.J., Frasch, A.C.C., A recombinant Trypanosoma cruzi trans-sialidase lacking the amino acid repeats retains the enzymatic activity (1994) Mol. Biochem. Parasitol., 64, pp. 337-340 | ||
| 504 | |a Couto, A.S., Goncalves, M.F., Colli, W., de Lederkremer, R.M., The N-linked carbohydrate chain of the 85-kilodalton glycoprotein from Trypanosoma cruzi trypomastigotes contains sialyl, fucosyl and galactosyl (alpha 1-3)galactose units (1990) Mol. Biochem. Parasitol., 39, pp. 101-107 | ||
| 504 | |a Buschiazzo, A., Amaya, M.F., Cremona, M.L., Frasch, A.C.C., Alzari, P.M., The crystal structure and mode of action of trans-sialidase, a key enzyme in Trypanosoma cruzi pathogenesis (2002) Mol. Cell, 10, pp. 757-768 | ||
| 504 | |a Amaya, M.F., Buschiazzo, A., Nguyen, T., Alzari, P.M., The high resolution structures of free and inhibitor-bound Trypanosoma rangeli sialidase and its comparison with T. cruzi trans-sialidase (2003) J. Mol. Biol., 325, pp. 773-784 | ||
| 504 | |a Amaya, M.F., Watts, A.G., Damager, I., Wehenkel, A., Nguyen, T., Buschiazzo, A., Paris, G., Alzari, P.M., Structural insights into the catalytic mechanism of Trypanosoma cruzi trans-sialidase (2004) Structure, 12, pp. 775-784 | ||
| 504 | |a Watts, A.G., Damager, I., Amaya, M.F., Buschiazzo, A., Alzari, P., Frasch, A.C.C., Withers, S.G., Trypanosoma cruzi Trans-sialidase operates through a covalent sialyl-enzyme intermediate: Tyrosine is the catalytic nucleophile (2003) J. Am. Chem. Soc., 125, pp. 7532-7533 | ||
| 504 | |a Buchini, S., Buschiazzo, A., Withers, S.G., A new generation of specific Trypanosoma cruzi trans-sialidase inhibitors (2008) Angew. Chem. Int. Ed., 47, pp. 2700-2703 | ||
| 504 | |a Yang, J., Schenkman, S., Horenstein, B.A., Primary 13C and beta-secondary 2H KIEs for trans-sialidase. A snapshot of nucleophilic participation during catálisis (2000) Biochemistry, 39, pp. 5902-5910 | ||
| 504 | |a Cremona, M.L., Sanchez, D.O., Frasch, A.C.C., Campetella, O., A single tyrosine differentiates active and inactive Trypanosoma cruzi trans-sialidases (1995) Gene, 160, pp. 123-128 | ||
| 504 | |a Todeschini, A.R., Dias, W.B., Girard, M.F., Wieruszeski, J.M., Mendonça-Previato, L., Previato, J.O., Enzymatically inactive trans-sialidase from Trypanosoma cruzi binds sialyl and beta-galactopyranosyl residues in a sequential ordered mechanism (2004) J. Biol. Chem., 279, pp. 5323-5328 | ||
| 504 | |a Agusti, R., Mendoza, V.M., Gallo-Rodriguez, C., de Lederkremer, R.M., Selective sialylation of 2,3-di-O-( β-d-galactopyranosyl)-d-galactose catalyzed by Trypanosoma cruzi trans-sialidase (2005) Tetrahedron: Asymmetry, 16, pp. 541-551 | ||
| 504 | |a Lee, S., Kim, B.H., trans-Sialidase catalyzed sialylation of beta-galactosyldisaccharide with an introduction of beta-galactosidase (2001) Enzyme Microb. Technol., 28, pp. 161-167 | ||
| 504 | |a Scudder, P., Doom, J.P., Chenkova, M., Manger, I.D., Pereira, M.E.S., Enzymatic characterization of beta-D-galactoside alpha 2,3-trans-sialidase from Trypanosoma cruzi (1993) J. Biol. Chem., 268, pp. 9886-9891 | ||
| 504 | |a Ribeirao, M., Pereira-Chioccola, V.L., Eichinger, D., Rodrigues, M.M., Schenkman, S., Temperature differences for trans-glycosylation and hydrolysis reaction reveal an acceptor binding site in the catalytic mechanism of Trypanosoma cruzi trans-sialidase (1997) Glycobiology, 7, pp. 1237-1246 | ||
| 504 | |a Harrison, J.A., Kartha, K.P., Turnbull, W.B., Scheuerl, S.L., Naismith, J.H., Schenkman, S., Field, R.A., Hydrolase and sialyltransferase activities of trypanosoma cruzi trans-sialidase towards NeuAc-alpha-2,3-gal-Gal-beta-O-PNP (2001) Bioorg. Med. Chem. Lett., 11, pp. 141-144 | ||
| 504 | |a Vetere, A., Paoletti, S., Complete synthesis of 3′-sialyl-N-acetyllactosamine by regioselective transglycosylation (1996) FEBS Lett., 399, pp. 203-206 | ||
| 504 | |a Vetere, A., Miletich, M., Bosco, M., Paoletti, S., Regiospecific glycosidase-assisted synthesis of lacto-N-biose I (Galβ1-3GlcNAc) and 3′-sialyl-lacto-N-biose I (NeuAcα2-3Galβ1-3GlcNAc) (2000) Eur. J. Biochem., 267, pp. 942-949 | ||
| 504 | |a Singh, S., Scigelova, M., Hallberg, M.L., Howarth, O.W., Crout, D.H.G., Schenkman, S., Synthesis of sialyloligosaccharides using the trans-sialidase from Trypanosoma cruzi: novel branched and di-sialylated products from digalactoside acceptors (2000) Chem. Commun., 12, pp. 1013-1014 | ||
| 504 | |a Probert, M.A., Milton, M.J., Harris, R., Schenkman, S., Brown, J.M., Homans, S.W., Field, R.A., Chemoenzymatic synthesis of GM3, Lewis x and sialyl Lewis x oligosaccharides in 13C-enriched form (1997) Tetrahedron Lett., 38, pp. 5861-5864 | ||
| 504 | |a Nishimura, S.I., Lee, K.B., Matsuoka, K., Lee, Y.C., Chemoenzymic preparation of a glycoconjugate polymer having a sialyloligosaccharide: Neu5Acα(2-3)Galβ (1-4)GlcNAc (1994) Biochem. Biophys. Res. Commun., 199, pp. 249-254 | ||
| 504 | |a Neubacher, B., Schmidt, D., Ziegelmuller, P., Thiem, J., Preparation of sialylated oligosaccharides employing recombinant trans-sialidase from Trypanosoma cruzi (2005) Org. Biomol. Chem., 3, pp. 1551-1556 | ||
| 504 | |a Neubacher, B., Scheid, S., Kelm, S., Frasch, A.C.C., Meyer, B., Thiem, J., Synthesis of Neu5Ac oligosaccharides and analogues by transglycosylation and their binding properties as ligands to MAG (2006) Chem Bio Chem., 7, pp. 896-899 | ||
| 504 | |a Kroger, L., Scudlo, A., Thiem, J., Subsequent enzymatic galactosylation and sialylation towards sialylated Thomsen-Friedenreich antigen components (2006) Adv. Synth. Catal., 348, pp. 1217-1227 | ||
| 504 | |a Lee, K.B., Lee, Y.C., Transfer of modified sialic acids by Trypanosoma cruzi trans-sialidase for attachment of functional groups to oligosaccharide (1994) Anal. Biochem., 216, pp. 358-364 | ||
| 504 | |a Takahashi, N., Lee, K.B., Nakagawa, H., Tsukamoto, Y., Kawamura, Y., Lee, Y.C., Enzymatic sialylation of N-linked oligosaccharides using an alpha-(2,3)-specific trans-sialidase from Trypanosoma cruzi: structural identification using a three-dimensional elution mapping technique (1995) Anal. Biochem., 230, pp. 333-342 | ||
| 504 | |a Paris, G., Ratier, L., Amaya, M.F., Nguyen, T., Alzari, P.A., Frasch, A.C.C., A sialidase mutant displaying trans-sialidase activity (2005) J. Mol. Biol., 345, pp. 923-934 | ||
| 504 | |a Engstler, M., Schauer, R., Ferrero-Garcia, M.A., Parodi, A.J., Storz-Eckerlin, T., Vasella, A., Witzig, C., Zhu, X., N-(4-Nitrophenyl)oxamic Acid and Related N-Acylanilines Are Non-competitive Inhibitors of vibrio cholerae sialidase but do not inhibit trypanosoma cruzi or trypanosoma brucei trans-sialidases (1994) Helv. Chim. Acta., 77, pp. 1166-1174 | ||
| 504 | |a Streicher, H., Busse, H., Building a successful structural motif into sialylmimetics-cyclohexenephosphonate monoesters as pseudo-sialosides with promising inhibitory properties (2006) Bioorg. Med. Chem., 14, pp. 1047-1057 | ||
| 504 | |a Ferrero-Garcia, M.A., Sanchez, D.O., Frasch, A.C.C., Parodi, A.J., The effect of pyridoxal 5′-phosphate and related compounds on Trypanosoma cruzi trans-sialidase (1993) An. Asoc. Quim. Argent, 81, pp. 127-132 | ||
| 504 | |a Neres, J., Bonnet, P., Edwards, P.N., Kotian, P.L., Buschiazzo, A., Alzari, P.M., Bryce, R.A., Douglas, K.T., Benzoic acid and pyridine derivatives as inhibitors of Trypanosoma cruzi trans-sialidase (2007) Bioorg. Med. Chem., 15, pp. 2106-2119 | ||
| 504 | |a Neres, J., Bryce, R.A., Douglas, K.T., Racional drug design in parasitology: trans-sialidase as a case of study for Chagas disease (2008) Drug. Discov. Today, 13, pp. 110-117 | ||
| 504 | |a Agusti, R., Paris, G., Ratier, L., Frasch, A.C.C., de Lederkremer, R.M., Lactose derivatives are inhibitors of Trypanosoma cruzi trans-sialidase activity toward conventional substrates in vitro and in vivo (2004) Glycobiology, 14, pp. 659-670 | ||
| 504 | |a Risso, M.G., Garbarino, G.B., Mocetti, E., Campetella, O., Gonzalez Cappa, S.M., Buscaglia, C.A., Leguizamon, M.S., Differential expression of a virulence factor, the trans-sialidase, by the main Trypanosoma cruzi phylogenetic lineages (2004) J. Infect. Dis., 189, pp. 2250-2259 | ||
| 504 | |a Leguizamon, M.S., Mocetti, E., García Rivello, H., Argibay, P.F., Campetella, O., trans-sialidase from Trypanosoma cruzi induces apoptosis in cells from the immune system in vivo (1999) J. Infect. Dis., 180, pp. 1398-1402 | ||
| 504 | |a Mucci, J., Hidalgo, A., Mocetti, E., Argibay, P.F., Leguizamon, M.S., Campetella, O., Thymocyte depletion in Trypanosoma cruzi infection is mediated by trans-sialidase-induced apoptosis on nurse cells complex (2002) Proc. Natl. Acad. Sci. USA, 99, pp. 3896-3901 | ||
| 504 | |a Mucci, J., Risso, M.G., Leguizamon, M.S., Frasch, A.C.C., Campetella, O., The trans-sialidase from Trypanosoma cruzi triggers apoptosis by target cell sialylation (2006) Cell Microbiol., 8, pp. 1086-1095 | ||
| 504 | |a Leguizamon, M.S., Campetella, O.E., Gonzalez-Cappa, S.M., Frasch, A.C.C., Mice infected with Trypanosoma cruzi produce antibodies against the enzymatic domain of trans-sialidase that inhibit its activity (1994) Infect. Immun., 62, pp. 3441-3446 | ||
| 504 | |a Leguizamon, M.S., Campetella, O., Russomando, G., Almiron, M., Guillen, I., Gonzalez Cappa, S.M., Frasch, A.C.C., Antibodies inhibiting Trypanosoma cruzi trans-sialidase activity in sera from human infections (1994) J. Infect. Dis., 170, pp. 1570-1574 | ||
| 504 | |a Risso, M.G., Pitcovsky, T.A., Caccuri, R.L., Campetella, O., Leguizamon, M.S., Immune system pathogenesis is prevented by the neutralization of the systemic trans-sialidase from Trypanosoma cruzi during severe infections (2007) Parasitology, 134, pp. 503-510 | ||
| 504 | |a Todeschini, A.R., Nunes, M.P., Pires, R.S., Lopes, M.F., Previato, J.O., Mendonça-Previato, L., DosReis, G.A., Costimulation of host T lymphocytes by a trypanosomal trans-sialidase: involvement of CD43 signaling (2002) J. Immunol., 168, pp. 5192-5198 | ||
| 504 | |a Dias, W.B., Fajardo, F.D., Graça-Souza, A.V., Freire-de-lima, L., Vieira, F., Girard, M.F., Bouteille, B., Todeschini, A.R., Endothelial cell signalling induced by trans-sialidase from Trypanosoma cruzi (2008) Cell. Microbiol., 10, pp. 88-99 | ||
| 504 | |a Vercelli, C.A., Hidalgo, A.M., Hyon, S.H., Argibay, P.F., Trypanosoma cruzi trans-sialidase inhibits human lymphocyte proliferation by nonapoptotic mechanisms: implications in pathogenesis and transplant immunology (2005) Transplant. Proc., 37, pp. 4594-4597 | ||
| 504 | |a Snary, D., Ferguson, M.A.J., Scott, M.T., Allen, A.K., Cell surface antigens of Trypanosoma cruzi: use of monoclonal antibodies to identify and isolate an epimastigote specific glycoprotein (1981) Mol. Biochem. Parasitol., 3, pp. 343-356 | ||
| 504 | |a Kirchhoff, L.V., Sher, A., Modifications of a 72 k surface glycoprotein (GP-72) of Trypanosoma cruzi during development (1985) Fed. Proc., 44, p. 1332 | ||
| 504 | |a Haynes, P.A., Cross, G.A., Differential glycosylation of epitope-tagged glycoprotein Gp72 during the Trypanosoma cruzi life cycle (1996) Mol. Biochem. Parasitol., 83, pp. 253-256 | ||
| 504 | |a Haynes, P.A., Ferguson, M.A.J., Cross, G.A., Structural characterization of novel oligosaccharides of cell-surface glycoproteins of Trypanosoma cruzi (1996) Glycobiology, 6, pp. 869-878 | ||
| 504 | |a Miletti, L.C., Mariño, K., Marino, C., Colli, W., Alves, M.J.M., de Lederkremer, R.M., Evidence for exo beta-d-galactofuranosidase in Trypanosoma cruzi (2003) Mol. Biochem. Parasitol., 127, pp. 85-88 | ||
| 504 | |a Cooper, R., Inverso, J.A., Espinosa, M., Nogueira, N.F., Cross, G.A., Characterization of a candidate gene for GP72, an insect stage-specific antigen of Trypanosoma cruzi (1991) Mol. Biochem. Parasitol., 49, pp. 45-59 | ||
| 504 | |a Cooper, R., de Jesus, A.R., Cross, G.A., Deletion of an immunodominant Trypanosoma cruzi surface glycoprotein disrupts flagellum-cell adhesion (1993) J. Cell Biol., 122, pp. 149-156 | ||
| 504 | |a de Jesus, A.R., Cooper, R., Espinosa, M., Gomes, J.E., Garcia, E.S., Paul, S., Cross, G.A., Gene deletion suggests a role for Trypanosoma cruzi surface glycoprotein GP72 in the insect and mammalian stages of the life cycle (1993) J. Cell Sci., 106, pp. 1023-1033 | ||
| 520 | 3 | |a The glycobiology of Trypanosoma cruzi, the causative agent of Chagas' disease, has contributed significantly to the identification of target enzymes responsible for the construction of unique cell-surface molecules. The authors discuss the structure of glycoinositolphospholipids, both free and as protein anchors in T. cruzi. The presence is emphasized of structural motifs that are absent in mammals. These include galactofuranose, aminoethylphosphonic acid, and inositolphosphoceramide. The mucins and the trans-sialidase (TcTS), both of which are involved in the infection process, are reviewed in detail in this chapter. The chemical synthesis of the oligosaccharides containing Galf is presented, as well as the use of the TcTS for synthetic purposes. © 2009 Elsevier Inc. All rights reserved. |l eng | |
| 593 | |a CHIDECAR, Departamento de Química Orgánica, Facultad de Ciencias Exactas y Naturales, Pabellon II, Ciudad Universitaria, 1428 Buenos Aires, Argentina | ||
| 690 | 1 | 0 | |a CHAGAS' DISEASE |
| 690 | 1 | 0 | |a GALACTOFURANOSE |
| 690 | 1 | 0 | |a GLYCOINOSITOLPHOSPHOLIPIDS |
| 690 | 1 | 0 | |a GPI ANCHORS |
| 690 | 1 | 0 | |a INOSITOLPHOSPHOCERAMIDE |
| 690 | 1 | 0 | |a MUCINS |
| 690 | 1 | 0 | |a TRANS-SIALIDASE |
| 690 | 1 | 0 | |a TRYPANOSOMA CRUZI |
| 690 | 1 | 0 | |a ALDITOL |
| 690 | 1 | 0 | |a AMINO ACID |
| 690 | 1 | 0 | |a ANTIGEN |
| 690 | 1 | 0 | |a CARBOHYDRATE |
| 690 | 1 | 0 | |a GLYCOCONJUGATE |
| 690 | 1 | 0 | |a GLYCOPROTEIN |
| 690 | 1 | 0 | |a LACTOSE |
| 690 | 1 | 0 | |a MUCIN |
| 690 | 1 | 0 | |a PHOSPHOLIPID |
| 690 | 1 | 0 | |a PROTEIN |
| 690 | 1 | 0 | |a SIALIC ACID DERIVATIVE |
| 690 | 1 | 0 | |a SIALIDASE |
| 690 | 1 | 0 | |a MEMBRANE PROTEIN |
| 690 | 1 | 0 | |a BINDING SITE |
| 690 | 1 | 0 | |a CARBOHYDRATE ANALYSIS |
| 690 | 1 | 0 | |a CATALYSIS |
| 690 | 1 | 0 | |a CELL SURFACE |
| 690 | 1 | 0 | |a GENETIC VARIABILITY |
| 690 | 1 | 0 | |a GLYCOBIOLOGY |
| 690 | 1 | 0 | |a INSECT |
| 690 | 1 | 0 | |a LIFE CYCLE |
| 690 | 1 | 0 | |a NONHUMAN |
| 690 | 1 | 0 | |a PARASITE |
| 690 | 1 | 0 | |a PRIORITY JOURNAL |
| 690 | 1 | 0 | |a REVIEW |
| 690 | 1 | 0 | |a SIALYLATION |
| 690 | 1 | 0 | |a TRYPANOSOMA CRUZI |
| 690 | 1 | 0 | |a ANIMAL |
| 690 | 1 | 0 | |a BIOSYNTHESIS |
| 690 | 1 | 0 | |a CHEMISTRY |
| 690 | 1 | 0 | |a GROWTH, DEVELOPMENT AND AGING |
| 690 | 1 | 0 | |a IMMUNOLOGY |
| 690 | 1 | 0 | |a METABOLISM |
| 690 | 1 | 0 | |a MOLECULAR GENETICS |
| 690 | 1 | 0 | |a MAMMALIA |
| 690 | 1 | 0 | |a TRYPANOSOMA CRUZI |
| 690 | 1 | 0 | |a ANIMALS |
| 690 | 1 | 0 | |a CARBOHYDRATE SEQUENCE |
| 690 | 1 | 0 | |a GLYCOCONJUGATES |
| 690 | 1 | 0 | |a GLYCOMICS |
| 690 | 1 | 0 | |a LIFE CYCLE STAGES |
| 690 | 1 | 0 | |a MEMBRANE GLYCOPROTEINS |
| 690 | 1 | 0 | |a MOLECULAR SEQUENCE DATA |
| 690 | 1 | 0 | |a TRYPANOSOMA CRUZI |
| 700 | 1 | |a Agusti, R. | |
| 773 | 0 | |d 2009 |g v. 62 |h pp. 311-366 |p Adv. Carbohydr. Chem. Biochem. |x 00652318 |w (AR-BaUEN)CENRE-121 |z 9780123747433 |t Advances in Carbohydrate Chemistry and Biochemistry | |
| 856 | 4 | 1 | |u https://www.scopus.com/inward/record.uri?eid=2-s2.0-66249110345&doi=10.1016%2fS0065-2318%2809%2900007-9&partnerID=40&md5=4c98c455c719f844fc31d89e0cde32b5 |y Registro en Scopus |
| 856 | 4 | 0 | |u https://doi.org/10.1016/S0065-2318(09)00007-9 |y DOI |
| 856 | 4 | 0 | |u https://hdl.handle.net/20.500.12110/paper_00652318_v62_n_p311_deLederkremer |y Handle |
| 856 | 4 | 0 | |u https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00652318_v62_n_p311_deLederkremer |y Registro en la Biblioteca Digital |
| 961 | |a paper_00652318_v62_n_p311_deLederkremer |b paper |c PE | ||
| 962 | |a info:eu-repo/semantics/article |a info:ar-repo/semantics/artículo |b info:eu-repo/semantics/publishedVersion | ||
| 999 | |c 69679 | ||